JP2010533178A5 - - Google Patents

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Publication number
JP2010533178A5
JP2010533178A5 JP2010516041A JP2010516041A JP2010533178A5 JP 2010533178 A5 JP2010533178 A5 JP 2010533178A5 JP 2010516041 A JP2010516041 A JP 2010516041A JP 2010516041 A JP2010516041 A JP 2010516041A JP 2010533178 A5 JP2010533178 A5 JP 2010533178A5
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JP
Japan
Prior art keywords
nucleic acid
ligand
acid molecules
molecules encoding
cationic liposome
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2010516041A
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English (en)
Japanese (ja)
Other versions
JP5890095B2 (ja
JP2010533178A (ja
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Publication date
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Priority claimed from PCT/US2008/008394 external-priority patent/WO2009009054A1/en
Publication of JP2010533178A publication Critical patent/JP2010533178A/ja
Publication of JP2010533178A5 publication Critical patent/JP2010533178A5/ja
Application granted granted Critical
Publication of JP5890095B2 publication Critical patent/JP5890095B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010516041A 2007-07-09 2008-07-09 カチオン性リポソーム媒介核酸送達を用いて免疫応答を引き起こす方法 Expired - Fee Related JP5890095B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92968507P 2007-07-09 2007-07-09
US60/929,685 2007-07-09
PCT/US2008/008394 WO2009009054A1 (en) 2007-07-09 2008-07-09 Methods for generating immune response using cationic-liposome-mediated nucleic acid delivery

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014089131A Division JP2014148533A (ja) 2007-07-09 2014-04-23 カチオン性リポソーム媒介核酸送達を用いて免疫応答を引き起こす方法

Publications (3)

Publication Number Publication Date
JP2010533178A JP2010533178A (ja) 2010-10-21
JP2010533178A5 true JP2010533178A5 (enExample) 2011-04-14
JP5890095B2 JP5890095B2 (ja) 2016-03-22

Family

ID=40228915

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2010516041A Expired - Fee Related JP5890095B2 (ja) 2007-07-09 2008-07-09 カチオン性リポソーム媒介核酸送達を用いて免疫応答を引き起こす方法
JP2014089131A Pending JP2014148533A (ja) 2007-07-09 2014-04-23 カチオン性リポソーム媒介核酸送達を用いて免疫応答を引き起こす方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014089131A Pending JP2014148533A (ja) 2007-07-09 2014-04-23 カチオン性リポソーム媒介核酸送達を用いて免疫応答を引き起こす方法

Country Status (15)

Country Link
US (1) US20090053299A1 (enExample)
EP (1) EP2175835B1 (enExample)
JP (2) JP5890095B2 (enExample)
KR (2) KR101570886B1 (enExample)
CN (2) CN106890142A (enExample)
AU (1) AU2008275713B2 (enExample)
BR (1) BRPI0814558A2 (enExample)
CA (1) CA2692546C (enExample)
EA (1) EA201070050A1 (enExample)
IL (1) IL203204B (enExample)
MX (1) MX2010000166A (enExample)
NZ (1) NZ582414A (enExample)
SG (1) SG182994A1 (enExample)
WO (1) WO2009009054A1 (enExample)
ZA (1) ZA201000038B (enExample)

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JP5573111B2 (ja) * 2009-11-06 2014-08-20 ライオン株式会社 イソプロピルメチルフェノール含有液体口腔用組成物
US20110182976A1 (en) * 2010-01-28 2011-07-28 National Taiwan Ocean University Lipoplex-patch based dna vaccine
WO2011105520A1 (ja) * 2010-02-26 2011-09-01 国立大学法人 長崎大学 抗原または薬物送達複合体
EP4043040B1 (en) * 2010-08-31 2023-01-11 GlaxoSmithKline Biologicals SA Small liposomes for delivery of immunogen-encoding rna
WO2012040101A1 (en) 2010-09-21 2012-03-29 University Of Miami Compositions and methods for inducing migration by dendritic cells and an immune response
WO2012040266A2 (en) * 2010-09-24 2012-03-29 University Of Miami Gene-based adjuvants and compositions thereof to increase antibody production in response to gene-based vaccines
KR20140038288A (ko) * 2012-09-19 2014-03-28 조지타운 유니버시티 표적화된 리포솜
US20140120157A1 (en) 2012-09-19 2014-05-01 Georgetown University Targeted liposomes
CN103405386B (zh) * 2012-09-21 2016-05-18 上海泽润生物科技有限公司 一种脂质体的制备方法及制作脂质体佐剂的方法
CA2901616A1 (en) * 2013-03-14 2014-10-02 Georgetown University Treatment for exposure to nerve agent
CN105726485B (zh) * 2016-03-24 2019-08-06 东华大学 一种半乳糖化壳聚糖修饰的免疫醇质体的制备方法
WO2020117715A1 (en) 2018-12-03 2020-06-11 Board Of Regents, The University Of Texas System Oligo-benzamide analogs and their use in cancer treatment
CN111840538A (zh) * 2020-05-29 2020-10-30 中山大学 一种水痘-带状疱疹病毒亚单位纳米疫苗的制备方法和应用
CN117883382B (zh) * 2023-11-27 2025-02-14 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） 高效递送疫苗的脂质体载体及脂质体疫苗的制备与用途

Family Cites Families (19)

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US4957735A (en) * 1984-06-12 1990-09-18 The University Of Tennessee Research Corporation Target-sensitive immunoliposomes- preparation and characterization
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5688488A (en) * 1989-04-03 1997-11-18 Purdue Research Foundation Composition and method for tumor imaging
US5753258A (en) * 1990-10-19 1998-05-19 University Of Florida Artificial viral envelopes
US6099842A (en) * 1990-12-03 2000-08-08 The United States Of America As Represented By The Department Of Health And Human Services Recombinant immunotoxin composed of a single chain antibody reacting with the human transferrin receptor and diptheria toxin
EP0671926B1 (en) * 1992-08-11 2002-11-13 President And Fellows Of Harvard College Immunomodulatory peptides
US5786214A (en) * 1994-12-15 1998-07-28 Spinal Cord Society pH-sensitive immunoliposomes and method of gene delivery to the mammalian central nervous system
FR2730637B1 (fr) * 1995-02-17 1997-03-28 Rhone Poulenc Rorer Sa Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
AU6113396A (en) * 1995-06-14 1997-01-15 Regents Of The University Of California, The Novel high affinity human antibodies to tumor antigens
US6210707B1 (en) * 1996-11-12 2001-04-03 The Regents Of The University Of California Methods of forming protein-linked lipidic microparticles, and compositions thereof
CA2271325A1 (en) * 1996-11-12 1998-05-22 The Regents Of The University Of California Preparation of stable formulations of lipid-nucleic acid complexes for efficient in vivo delivery
US6794128B2 (en) * 1998-04-24 2004-09-21 The Regents Of The University Of California Methods of selecting internalizing antibodies
US20030022854A1 (en) * 1998-06-25 2003-01-30 Dow Steven W. Vaccines using nucleic acid-lipid complexes
PT1811036E (pt) 1999-02-22 2011-07-11 Univ Georgetown Imunolipossomas dirigidos por fragmento de anticorpo para distribuição sistémica de genes
US9034329B2 (en) * 1999-02-22 2015-05-19 Georgetown University Preparation of antibody or an antibody fragment-targeted immunoliposomes for systemic administration of therapeutic or diagnostic agents and uses thereof
US7780882B2 (en) 1999-02-22 2010-08-24 Georgetown University Simplified and improved method for preparing an antibody or an antibody fragment targeted immunoliposome for systemic administration of a therapeutic or diagnostic agent
US20020103165A1 (en) * 2000-02-29 2002-08-01 Alliance Pharmaceutical Corp., Engineered spray-dried lipid-based microparticles for cellular targeting
CN1798545B (zh) 2003-06-04 2013-06-05 乔治敦大学 改良脂质体复合物的稳定性和保存期的方法
KR20080064169A (ko) * 2005-10-20 2008-07-08 조지타운 유니버시티 암의 초기 ｍｒｉ 검출을 개선하기 위한 종양-표적화나노전달 시스템

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