JP2010533012A5 - - Google Patents
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- Publication number
- JP2010533012A5 JP2010533012A5 JP2010515495A JP2010515495A JP2010533012A5 JP 2010533012 A5 JP2010533012 A5 JP 2010533012A5 JP 2010515495 A JP2010515495 A JP 2010515495A JP 2010515495 A JP2010515495 A JP 2010515495A JP 2010533012 A5 JP2010533012 A5 JP 2010533012A5
- Authority
- JP
- Japan
- Prior art keywords
- implant
- oxide layer
- strontium
- ions
- deposit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007943 implant Substances 0.000 claims 41
- 238000000034 method Methods 0.000 claims 19
- 210000000988 bone and bone Anatomy 0.000 claims 10
- 229910001427 strontium ion Inorganic materials 0.000 claims 9
- 238000002513 implantation Methods 0.000 claims 6
- 150000002500 ions Chemical class 0.000 claims 5
- 229910044991 metal oxide Inorganic materials 0.000 claims 5
- 150000004706 metal oxides Chemical group 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
- 229910052712 strontium Inorganic materials 0.000 claims 5
- CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 claims 5
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 4
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 claims 4
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims 4
- 239000002269 analeptic agent Substances 0.000 claims 4
- 229910052791 calcium Inorganic materials 0.000 claims 4
- 239000011575 calcium Substances 0.000 claims 4
- 229910052744 lithium Inorganic materials 0.000 claims 4
- 229910052749 magnesium Inorganic materials 0.000 claims 4
- 239000011777 magnesium Substances 0.000 claims 4
- 229910052751 metal Inorganic materials 0.000 claims 4
- 239000002184 metal Substances 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- UUCCCPNEFXQJEL-UHFFFAOYSA-L strontium dihydroxide Chemical compound [OH-].[OH-].[Sr+2] UUCCCPNEFXQJEL-UHFFFAOYSA-L 0.000 claims 4
- 229910001866 strontium hydroxide Inorganic materials 0.000 claims 4
- 238000005422 blasting Methods 0.000 claims 3
- 239000000843 powder Substances 0.000 claims 3
- 238000005185 salting out Methods 0.000 claims 3
- 239000000243 solution Substances 0.000 claims 3
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 2
- 229910001069 Ti alloy Inorganic materials 0.000 claims 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical group O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims 2
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims 2
- 239000012670 alkaline solution Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 229910052731 fluorine Inorganic materials 0.000 claims 2
- 239000011737 fluorine Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000011164 ossification Effects 0.000 claims 2
- 238000001556 precipitation Methods 0.000 claims 2
- IATRAKWUXMZMIY-UHFFFAOYSA-N strontium oxide Chemical group [O-2].[Sr+2] IATRAKWUXMZMIY-UHFFFAOYSA-N 0.000 claims 2
- 239000010936 titanium Substances 0.000 claims 2
- 229910052719 titanium Inorganic materials 0.000 claims 2
- 229910000389 calcium phosphate Inorganic materials 0.000 claims 1
- 239000001506 calcium phosphate Substances 0.000 claims 1
- -1 calcium phosphate compound Chemical class 0.000 claims 1
- 235000011010 calcium phosphates Nutrition 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000002244 precipitate Substances 0.000 claims 1
- 230000001376 precipitating effect Effects 0.000 claims 1
- 239000004408 titanium dioxide Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07112078.6 | 2007-07-09 | ||
| EP07112078A EP2014319A1 (en) | 2007-07-09 | 2007-07-09 | A bone tissue implant comprising strontium ions |
| PCT/EP2008/058859 WO2009007372A2 (en) | 2007-07-09 | 2008-07-08 | A bone tissue implant comprising strontium ions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010533012A JP2010533012A (ja) | 2010-10-21 |
| JP2010533012A5 true JP2010533012A5 (enExample) | 2011-08-11 |
| JP5487102B2 JP5487102B2 (ja) | 2014-05-07 |
Family
ID=38969811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010515495A Active JP5487102B2 (ja) | 2007-07-09 | 2008-07-08 | ストロンチウムイオンを含む骨組織インプラント |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9889227B2 (enExample) |
| EP (2) | EP2014319A1 (enExample) |
| JP (1) | JP5487102B2 (enExample) |
| KR (1) | KR20100057796A (enExample) |
| CN (1) | CN101687062B (enExample) |
| AU (1) | AU2008274302B2 (enExample) |
| BR (1) | BRPI0813563B1 (enExample) |
| CA (1) | CA2692388A1 (enExample) |
| WO (1) | WO2009007372A2 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0902705D0 (en) * | 2009-02-19 | 2009-04-01 | Neoss Ltd | Surface treatment process for implant |
| WO2012003502A2 (en) * | 2010-07-02 | 2012-01-05 | University Of Florida Research Foundation, Inc. | Bioresorbable metal alloy and implants made of same |
| US11491257B2 (en) | 2010-07-02 | 2022-11-08 | University Of Florida Research Foundation, Inc. | Bioresorbable metal alloy and implants |
| US20120195848A1 (en) * | 2011-01-27 | 2012-08-02 | The University Of Hong Kong | Strontium-containing bioactive bone cement |
| EP2522373A1 (en) * | 2011-05-11 | 2012-11-14 | Dentsply IH AB | Biocompatible component |
| EP2723410B1 (en) * | 2011-06-24 | 2018-04-18 | Straumann Holding AG | Body made of a ceramic material |
| KR101213355B1 (ko) * | 2011-12-27 | 2012-12-18 | 오스템임플란트 주식회사 | 초기 안정성이 증진된 치과용 임플란트 및 그 제조 방법 |
| CN102492974A (zh) * | 2011-12-30 | 2012-06-13 | 浙江大学 | 钛种植体表面制备可降解镁掺杂非晶态磷酸钙涂层的方法 |
| WO2013142480A1 (en) * | 2012-03-20 | 2013-09-26 | Titan Spine, Llc | Friction-fit spinal endplate and endplate-preserving method |
| EP2641621A1 (en) * | 2012-03-23 | 2013-09-25 | Elos Medtech Pinol A/S | Strontium based coating for body implants |
| WO2014027612A1 (ja) * | 2012-08-16 | 2014-02-20 | 学校法人中部大学 | 骨修復材料及びその製造方法 |
| EP2716261A1 (en) * | 2012-10-02 | 2014-04-09 | Titan Spine, LLC | Implants with self-deploying anchors |
| EP2716306A1 (en) * | 2012-10-05 | 2014-04-09 | Aarhus Universitet | Metal oxide functionalized by strontium |
| WO2015003112A1 (en) | 2013-07-03 | 2015-01-08 | University Of Florida Research Foundation, Inc. | Biodegradable magnesium alloys, methods of manufacture thereof and articles comprising the same |
| WO2015069724A1 (en) | 2013-11-05 | 2015-05-14 | University Of Florida Research Foundation, Inc. | Articles comprising reversibly attached screws comprising a biodegradable composition, methods of manufacture thereof and uses thereof |
| US10687956B2 (en) | 2014-06-17 | 2020-06-23 | Titan Spine, Inc. | Corpectomy implants with roughened bioactive lateral surfaces |
| US10188770B2 (en) | 2014-06-26 | 2019-01-29 | Osstemimplant Co., Ltd. | Dental implant having enhanced early stability and method for manufacturing same |
| WO2016118444A1 (en) | 2015-01-23 | 2016-07-28 | University Of Florida Research Foundation, Inc. | Radiation shielding and mitigating alloys, methods of manufacture thereof and articles comprising the same |
| FR3034678A1 (fr) * | 2015-04-07 | 2016-10-14 | Geocorail | Dispositif, procede et compose pour la reconstruction osseuse d'un vertebre. |
| TWI726940B (zh) | 2015-11-20 | 2021-05-11 | 美商泰坦脊柱股份有限公司 | 積層製造整形外科植入物之方法 |
| JP2019527591A (ja) | 2016-08-03 | 2019-10-03 | タイタン スパイン インコーポレイテッドTitan Spine,Inc. | 骨誘導を増強するインプラント表面 |
| CN106691609B (zh) * | 2016-11-24 | 2022-04-15 | 北京华钽生物科技开发有限公司 | 一种高亲组织耐腐蚀种植牙及其制造方法 |
| CN106492280B (zh) * | 2016-11-24 | 2022-03-01 | 北京华钽生物科技开发有限公司 | 一种抗感染、耐摩擦、生物相容性高人工关节制品及其制造方法 |
| CN110494098B (zh) * | 2017-03-21 | 2021-10-22 | 朝鲜大学校产学协力团 | 在等离子电解氧化工序中含有金属和硅的电解质组合物及牙科用植牙的制造方法 |
| CN111787928A (zh) * | 2017-07-31 | 2020-10-16 | 慧创骨科药品有限公司 | 提高骨密度的多矿物质补充剂 |
| CN108042846B (zh) * | 2018-01-15 | 2020-11-24 | 陕西科技大学 | 一种锶掺杂钽氧化物纳米棒结构生物活性涂层的制备方法 |
| CN110559477A (zh) * | 2018-11-01 | 2019-12-13 | 赵全明 | 一种医用钛合金表面含锰羟基磷灰石/二氧化钛生物陶瓷涂层及其制备方法 |
| CN110241453A (zh) * | 2019-04-25 | 2019-09-17 | 西南大学 | 一种缓释氟和铈的可降解锌合金骨钉及其制备方法 |
| CN110304939B (zh) * | 2019-07-15 | 2020-07-31 | 四川大学 | 用于牙槽骨缺损修复的掺锶磷酸钙陶瓷颗粒及其制备方法 |
| CN111467572B (zh) * | 2020-04-09 | 2022-07-29 | 上海交通大学医学院附属第九人民医院 | 一种种植体材料及其制备方法与应用 |
| CN111821506A (zh) * | 2020-06-16 | 2020-10-27 | 温州医科大学附属口腔医院 | 一种锶/银纳米涂层改性的骨仿生钛种植体的制备 |
| CN112545713A (zh) * | 2020-11-23 | 2021-03-26 | 天衍医疗器材有限公司 | 一种骨填充假体及其制备工艺 |
| CN112773931B (zh) * | 2021-01-04 | 2022-06-21 | 北京华钽生物科技开发有限公司 | 一种可吸收的增强骨植入物材料及其制备方法 |
| KR102585073B1 (ko) * | 2022-03-17 | 2023-10-06 | 구본준 | 플라즈마 용융 분사법을 이용한 임플란트 식립체의 표면 코팅 방법 |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
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| IT1007601B (it) | 1973-02-10 | 1976-10-30 | Friedrichsfeld Gmbh | Endoprotesi ortopedica special mente articolare |
| CH568067A5 (enExample) | 1973-05-17 | 1975-10-31 | Friedrichsfeld Gmbh | |
| US3919723A (en) | 1974-05-20 | 1975-11-18 | Friedrichsfeld Gmbh | Bone shaft or bone joint prosthesis and process |
| DE2546824C2 (de) * | 1975-10-18 | 1986-05-07 | Ernst Leitz Wetzlar Gmbh, 6330 Wetzlar | Beschichtete Endoprothese und Verfahren zu ihrer Herstellung |
| US4097935A (en) * | 1976-07-21 | 1978-07-04 | Sterling Drug Inc. | Hydroxylapatite ceramic |
| DE3433210C1 (de) * | 1984-09-10 | 1986-06-05 | Hans Dr.med. Dr.med.dent. 8000 München Scheicher | Mittel zur Fuellung von Knochen- und Zahndefekten,zum Knochenaufbau,fuer Knochenkontaktschichten und fuer Knochen- und Zahnwurzelersatz und Verwendung von Carbonatapatit fuer diesen Zweck |
| US4737411A (en) * | 1986-11-25 | 1988-04-12 | University Of Dayton | Controlled pore size ceramics particularly for orthopaedic and dental applications |
| JP3198125B2 (ja) * | 1991-06-18 | 2001-08-13 | 株式会社アドバンス | インプラントの製造方法 |
| US5578314A (en) * | 1992-05-29 | 1996-11-26 | The Regents Of The University Of California | Multiple layer alginate coatings of biological tissue for transplantation |
| NO924697D0 (no) | 1992-12-04 | 1992-12-04 | Jan Erik Ellingsen | Kirurgisk implantat og en fremgangsmaate for behandling avkirurgisk implantat |
| US5372660A (en) | 1993-08-26 | 1994-12-13 | Smith & Nephew Richards, Inc. | Surface and near surface hardened medical implants |
| ATE337032T1 (de) | 1993-12-20 | 2006-09-15 | Astra Tech Ab | Verfahren zur behandlung eines implantates aus titan oder titanlegierung |
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| US5705273A (en) * | 1995-03-08 | 1998-01-06 | The Ohio State University | Method for strengthening dental restorative materials |
| SE513556C2 (sv) * | 1997-11-11 | 2000-10-02 | Nobel Biocare Ab | Implantatelement med tunt ytskickt applicerat genom het isostatisk pressning |
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| US7291178B2 (en) * | 2001-05-29 | 2007-11-06 | Mediteam Dental Ab | Modified oxide |
| DE10128100A1 (de) | 2001-06-11 | 2002-12-19 | Hannover Med Hochschule | Medizinisches Implantat für den menschlichen und tierischen Körper |
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| GB0126467D0 (en) | 2001-11-03 | 2002-01-02 | Accentus Plc | Deposition of coatings on substrates |
| SE523288C2 (sv) * | 2002-07-19 | 2004-04-06 | Astra Tech Ab | Ett implantat och ett förfarande för behandling av en implantatyta |
| SE523236C2 (sv) | 2002-07-19 | 2004-04-06 | Astra Tech Ab | Ett implantat och ett förfarande för behandling av en implantatyta |
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| DE10243132B4 (de) * | 2002-09-17 | 2006-09-14 | Biocer Entwicklungs Gmbh | Antiinfektiöse, biokompatible Titanoxid-Beschichtungen für Implantate sowie Verfahren zu deren Herstellung |
| CN1313378C (zh) * | 2002-09-24 | 2007-05-02 | 北京化工大学 | 制备钛酸锶粉体的方法 |
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| WO2004098619A2 (en) | 2003-05-07 | 2004-11-18 | Osteologix A/S | Treating cartilage / bone conditions with water-soluble strontium salts |
| US6905723B2 (en) | 2003-05-30 | 2005-06-14 | Depuy Products, Inc. | Strontium-substituted apatite coating |
| US7223079B2 (en) * | 2003-07-28 | 2007-05-29 | The Coca-Cola Company | Quick loading peristaltic pump |
| JP4635177B2 (ja) * | 2003-09-02 | 2011-02-16 | 独立行政法人産業技術総合研究所 | 生体親和性インプラント材及びその製造方法 |
| DE10347347B4 (de) * | 2003-10-11 | 2006-02-16 | Daimlerchrysler Ag | Wählhebel und Verfahren zur Montage eines Wählhebels |
| CA2546238A1 (en) | 2003-11-13 | 2005-05-26 | Lifenova Biomedical, S.A. | Method of producing endosseous implants or medical prostheses by means of ion implantation, and endosseous implant or medical prosthesis thus obtained |
| BRPI0411404A (pt) | 2004-03-04 | 2006-07-25 | Young-Taek Sul | implante de titanato de magnésio osseoindutivo e processo de fabricação do mesmo |
| KR100714244B1 (ko) * | 2004-04-26 | 2007-05-02 | 한국기계연구원 | 생체용 골유도성 금속 임플란트 및 그 제조방법 |
| CA2574115A1 (en) | 2004-07-21 | 2006-01-26 | The University Of British Columbia | Method of electrolytically depositing a pharmaceutical coating onto a conductive osteal implant |
| JP4403549B2 (ja) | 2004-09-15 | 2010-01-27 | 日本ビクター株式会社 | 動画像符号化装置及び動画像符号化用プログラム |
| US20060286136A1 (en) * | 2005-06-15 | 2006-12-21 | Cabot Microelectronics Corporation | Surface treatment of biomedical implant for improved biomedical performance |
| WO2008109016A1 (en) * | 2007-03-05 | 2008-09-12 | Signal Medical Corporation | Metal/alloy coated ceramic |
-
2007
- 2007-07-09 EP EP07112078A patent/EP2014319A1/en not_active Withdrawn
-
2008
- 2008-07-08 CN CN200880024025.8A patent/CN101687062B/zh active Active
- 2008-07-08 US US12/299,010 patent/US9889227B2/en active Active
- 2008-07-08 BR BRPI0813563-0A patent/BRPI0813563B1/pt active IP Right Grant
- 2008-07-08 EP EP08774896.8A patent/EP2187982B1/en active Active
- 2008-07-08 WO PCT/EP2008/058859 patent/WO2009007372A2/en not_active Ceased
- 2008-07-08 KR KR1020107002822A patent/KR20100057796A/ko not_active Withdrawn
- 2008-07-08 JP JP2010515495A patent/JP5487102B2/ja active Active
- 2008-07-08 CA CA002692388A patent/CA2692388A1/en not_active Abandoned
- 2008-07-08 AU AU2008274302A patent/AU2008274302B2/en active Active
-
2012
- 2012-08-21 US US13/591,147 patent/US9744263B2/en active Active
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