|
DK2214701T3
(en)
*
|
2007-11-01 |
2016-12-12 |
Univ Arkansas |
CONFIGURATIONS AND METHODS FOR IMPROVING THE IMMUNE RESPONSES TO Eimeria
|
|
EP2540740B1
(en)
|
2008-06-17 |
2014-09-10 |
Apogenix GmbH |
Multimeric TNF receptors
|
|
DK2604693T3
(en)
*
|
2008-07-21 |
2016-05-30 |
Apogenix Gmbh |
Single-chain TNFSF molecules
|
|
WO2010068754A2
(en)
|
2008-12-10 |
2010-06-17 |
Paka Pulmonary Pharmaceuticals, Inc. |
Methods and compositions for delivery of medicaments to the lungs
|
|
JP5844158B2
(ja)
*
|
2009-01-09 |
2016-01-13 |
アポゲニクス ゲゼルシャフト ミット ベシュレンクテル ハフツングＡｐｏｇｅｎｉｘ ＧｍｂＨ |
三量体形成融合タンパク質
|
|
CN101698852B
(zh)
*
|
2009-10-23 |
2014-08-13 |
江苏先声药物研究有限公司 |
具有cd137l功能的蛋白或多肽及其基因和应用
|
|
JP4918627B2
(ja)
*
|
2010-02-26 |
2012-04-18 |
積水メディカル株式会社 |
偽陽性反応を抑制する検体抽出液
|
|
US8932575B2
(en)
|
2010-09-21 |
2015-01-13 |
University Of Miami |
Compositions and methods for inducing migration by dendritic cells and an immune response
|
|
WO2012040266A2
(en)
*
|
2010-09-24 |
2012-03-29 |
University Of Miami |
Gene-based adjuvants and compositions thereof to increase antibody production in response to gene-based vaccines
|
|
HRP20150664T1
(hr)
*
|
2010-12-03 |
2015-07-31 |
Adamed Sp. Z O.O. |
Antikancerogeni fuzijski protein
|
|
EP2586793A1
(en)
*
|
2011-10-27 |
2013-05-01 |
Centre National de la Recherche Scientifique |
Chimeric molecule involving oligomerized FasL extracellular domain
|
|
US20150191506A1
(en)
*
|
2012-06-29 |
2015-07-09 |
Asahi Kasei Medical Co., Ltd. |
Adsorbent consisting of carrier which bound with polypeptide comprising b-domain mutant derived from protein a
|
|
NO2776305T3
(https=)
|
2014-04-23 |
2018-01-27 |
|
|
|
WO2016079527A1
(en)
|
2014-11-19 |
2016-05-26 |
Tetralogic Birinapant Uk Ltd |
Combination therapy
|
|
WO2016097773A1
(en)
|
2014-12-19 |
2016-06-23 |
Children's Cancer Institute |
Therapeutic iap antagonists for treating proliferative disorders
|
|
MA41460A
(fr)
|
2015-02-03 |
2017-12-12 |
Oncomed Pharm Inc |
Agents de liaison à la tnfrsf et leurs utilisations
|
|
CN108289966A
(zh)
*
|
2015-09-24 |
2018-07-17 |
北卡罗来纳-查佩尔山大学 |
用于减少转移的方法和组合物
|
|
CA3002741A1
(en)
*
|
2015-10-23 |
2017-04-27 |
Apogenix Ag |
Single-chain gitr-receptor agonist proteins
|
|
EP3368558A1
(en)
|
2015-10-28 |
2018-09-05 |
Apogenix AG |
Single-chain tl1a receptor agonist proteins
|
|
TWI788307B
(zh)
|
2016-10-31 |
2023-01-01 |
美商艾歐凡斯生物治療公司 |
用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
|
|
CA3049165A1
(en)
|
2017-01-06 |
2018-07-12 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof
|
|
BR112019013940A2
(pt)
|
2017-01-06 |
2020-02-11 |
Iovance Biotherapeutics, Inc. |
Método de tratar um câncer com uma população de linfócitos infiltrantes de tumor, processo para preparação de uma população de linfócitos infiltrantes de tumor, população de linfócitos infiltrantes de tumor, e, composição farmacêutica.
|
|
US11142558B2
(en)
|
2017-04-06 |
2021-10-12 |
Universität Stuttgart |
Tumor necrosis factor receptor (TNFR) binding protein complex with improved binding and bioactivity
|
|
US20200224161A1
(en)
|
2017-05-10 |
2020-07-16 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof
|
|
EP3635097A1
(en)
|
2017-06-05 |
2020-04-15 |
Iovance Biotherapeutics, Inc. |
Methods of using tumor infiltrating lymphocytes in double-refractory melanoma
|
|
EP3973973A1
(en)
|
2017-10-31 |
2022-03-30 |
KaliVir Immunotherapeutics, Inc. |
Platform oncolytic vector for systemic delivery
|
|
EP4501408A3
(en)
|
2017-11-17 |
2025-04-09 |
Iovance Biotherapeutics, Inc. |
Til expansion from fine needle aspirates and small biopsies
|
|
EP3714041A1
(en)
|
2017-11-22 |
2020-09-30 |
Iovance Biotherapeutics, Inc. |
Expansion of peripheral blood lymphocytes (pbls) from peripheral blood
|
|
EP3724885A2
(en)
|
2017-12-15 |
2020-10-21 |
Iovance Biotherapeutics, Inc. |
Systems and methods for determining the beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof and beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof
|
|
WO2019136459A1
(en)
|
2018-01-08 |
2019-07-11 |
Iovance Biotherapeutics, Inc. |
Processes for generating til products enriched for tumor antigen-specific t-cells
|
|
US11713446B2
(en)
|
2018-01-08 |
2023-08-01 |
Iovance Biotherapeutics, Inc. |
Processes for generating TIL products enriched for tumor antigen-specific T-cells
|
|
SG11202006541UA
(en)
|
2018-01-08 |
2020-08-28 |
Iovance Biotherapeutics Inc |
Processes for generating til products enriched for tumor antigen-specific t-cells
|
|
CA3090795A1
(en)
|
2018-02-13 |
2019-08-22 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes (tils) with adenosine a2a receptor antagonists and therapeutic combinations of tils and adenosine a2a receptor antagonists
|
|
MA52667B1
(fr)
|
2018-03-29 |
2024-07-31 |
Iovance Biotherapeutics, Inc. |
Procédés de production de lymphocytes infiltrant les tumeurs et leurs utilisations en immunothérapie
|
|
US20210130779A1
(en)
|
2018-04-27 |
2021-05-06 |
Iovance Biotherapeutics, Inc. |
Closed process for expansion and gene editing of tumor infiltrating lymphocytes and uses of same in immunotherapy
|
|
WO2019217753A1
(en)
|
2018-05-10 |
2019-11-14 |
Iovance Biotherapeutics, Inc. |
Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
|
|
CN112566926A
(zh)
*
|
2018-06-14 |
2021-03-26 |
南特生物公司 |
Tnf型受体-配体融合蛋白及方法
|
|
TW202031273A
(zh)
|
2018-08-31 |
2020-09-01 |
美商艾歐凡斯生物治療公司 |
抗ｐｄ－１抗體難治療性之非小細胞肺癌（ｎｓｃｌｃ）病患的治療
|
|
CA3112599A1
(en)
|
2018-09-20 |
2020-03-26 |
Iovance Biotherapeutics, Inc. |
Expansion of tils from cryopreserved tumor samples
|
|
TW202039831A
(zh)
|
2018-11-05 |
2020-11-01 |
美商艾歐凡斯生物治療公司 |
對抗ｐｄ－１抗體呈現難治性之非小細胞肺癌（ｎｓｃｌｃ）病患之治療
|
|
US20230039976A1
(en)
|
2018-11-05 |
2023-02-09 |
Iovance Biotherapeutics, Inc. |
Selection of improved tumor reactive t-cells
|
|
TW202039830A
(zh)
|
2018-11-05 |
2020-11-01 |
美商艾歐凡斯生物治療公司 |
用於製造腫瘤浸潤性淋巴細胞之方法及其在免疫療法中之用途
|
|
CA3118493A1
(en)
|
2018-11-05 |
2020-05-14 |
Iovance Biotherapeutics, Inc. |
Expansion of tils utilizing akt pathway inhibitors
|
|
JP7710372B2
(ja)
|
2018-12-19 |
2025-07-18 |
アイオバンス バイオセラピューティクス，インコーポレイテッド |
操作されたサイトカイン受容体対を使用して腫瘍浸潤リンパ球を拡大培養する方法及びその使用
|
|
US20220135649A1
(en)
*
|
2019-02-06 |
2022-05-05 |
The Regents Of The University Of California |
Dominant negative cd40l polypeptides
|
|
CN113677712A
(zh)
*
|
2019-02-15 |
2021-11-19 |
爱披萨佛公司 |
染色质相关蛋白的定量作图
|
|
US20220133795A1
(en)
|
2019-03-01 |
2022-05-05 |
Iovance Biotherapeutics, Inc. |
Expansion of Tumor Infiltrating Lymphocytes From Liquid Tumors and Therapeutic Uses Thereof
|
|
WO2020180144A1
(ko)
*
|
2019-03-07 |
2020-09-10 |
경북대학교 산학협력단 |
트레일 트라이머와 암표적 펩타이드를 멀티디스플레이하는 페리틴 나노케이지 및 이의 항암제로서의 용도
|
|
CA3134144A1
(en)
|
2019-03-29 |
2020-10-08 |
Myst Therapeutics, Llc |
Ex vivo methods for producing a t cell therapeutic and related compositions and methods
|
|
US20220249559A1
(en)
|
2019-05-13 |
2022-08-11 |
Iovance Biotherapeutics, Inc. |
Methods and compositions for selecting tumor infiltrating lymphocytes and uses of the same in immunotherapy
|
|
EP4582442A3
(en)
|
2019-06-24 |
2025-10-29 |
Universität Stuttgart |
Tnfr2 agonists with improved stability
|
|
JP2022553389A
(ja)
|
2019-10-25 |
2022-12-22 |
アイオバンス バイオセラピューティクス，インコーポレイテッド |
腫瘍浸潤リンパ球の遺伝子編集及び免疫療法におけるその使用
|
|
CA3162703A1
(en)
|
2019-11-27 |
2021-06-03 |
Myst Therapeutics, Llc |
Method of producing tumor-reactive t cell composition using modulatory agents
|
|
US12516291B2
(en)
|
2019-12-11 |
2026-01-06 |
Iovance Biotherapeutics, Inc. |
Processes for the production of tumor infiltrating lymphocytes (TILs) and methods of using the same
|
|
JP7817937B2
(ja)
|
2020-02-27 |
2026-02-19 |
ターンストーン バイオロジクス コーポレイション |
腫瘍反応性ｔ細胞のエクスビボ富化および増大のための方法ならびに関連するその組成物
|
|
EP4146794A1
(en)
|
2020-05-04 |
2023-03-15 |
Iovance Biotherapeutics, Inc. |
Processes for production of tumor infiltrating lymphocytes and uses of the same in immunotherapy
|
|
TW202208616A
(zh)
|
2020-05-04 |
2022-03-01 |
美商艾歐凡斯生物治療公司 |
改良之腫瘤反應性ｔ細胞的選擇
|
|
WO2022076606A1
(en)
|
2020-10-06 |
2022-04-14 |
Iovance Biotherapeutics, Inc. |
Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
|
|
US20230372397A1
(en)
|
2020-10-06 |
2023-11-23 |
Iovance Biotherapeutics, Inc. |
Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
|
|
WO2022079308A1
(en)
*
|
2020-10-16 |
2022-04-21 |
Institut Pasteur |
Chimeric constructs useful in vaccination and cancer therapy
|
|
CA3197371A1
(en)
|
2020-11-19 |
2022-05-27 |
Kalivir Immunotherapeutics, Inc. |
Oncolytic immunotherapy by tumor micro-environment remodeling
|
|
TW202241468A
(zh)
|
2020-12-11 |
2022-11-01 |
美商艾歐凡斯生物治療公司 |
用腫瘤浸潤性淋巴球療法與ｂｒａｆ抑制劑及／或ｍｅｋ抑制劑組合治療癌症患者
|
|
CA3202483A1
(en)
|
2020-12-17 |
2022-06-23 |
Maria Fardis |
Treatment with tumor infiltrating lymphocyte therapies in combination with ctla-4 and pd-1 inhibitors
|
|
US20240123067A1
(en)
|
2020-12-17 |
2024-04-18 |
Iovance Biotherapeutics, Inc. |
Treatment of cancers with tumor infiltrating lymphocyte therapies
|
|
CA3207359A1
(en)
|
2021-02-05 |
2022-08-11 |
Cecile Chartier-Courtaud |
Adjuvant therapy for cancer
|
|
WO2022187741A2
(en)
|
2021-03-05 |
2022-09-09 |
Iovance Biotherapeutics, Inc. |
Tumor storage and cell culture compositions
|
|
AU2022246174A1
(en)
|
2021-03-25 |
2023-09-14 |
Iovance Biotherapeutics, Inc. |
Methods and compositions for t-cell coculture potency assays and use with cell therapy products
|
|
EP4326287A2
(en)
|
2021-04-19 |
2024-02-28 |
Iovance Biotherapeutics, Inc. |
Chimeric costimulatory receptors, chemokine receptors, and the use of same in cellular immunotherapies
|
|
EP4329786A4
(en)
|
2021-04-30 |
2024-12-11 |
KaliVir Immunotherapeutics, Inc. |
Oncolytic viruses for modified mhc expression
|
|
WO2022245754A1
(en)
|
2021-05-17 |
2022-11-24 |
Iovance Biotherapeutics, Inc. |
Pd-1 gene-edited tumor infiltrating lymphocytes and uses of same in immunotherapy
|
|
IL309186A
(en)
*
|
2021-06-17 |
2024-02-01 |
Kalivir Immunotherapeutics Inc |
TNFSF-L fusion proteins and their uses
|
|
US20240342285A1
(en)
|
2021-07-28 |
2024-10-17 |
Iovance Biotherapeutics, Inc. |
Treatment of cancer patients with tumor infiltrating lymphocyte therapies in combination with kras inhibitors
|
|
EP4404969A1
(en)
|
2021-09-24 |
2024-07-31 |
Iovance Biotherapeutics, Inc. |
Expansion processes and agents for tumor infiltrating lymphocytes
|
|
WO2023077015A2
(en)
|
2021-10-27 |
2023-05-04 |
Iovance Biotherapeutics, Inc. |
Systems and methods for coordinating manufacturing of cells for patient-specific immunotherapy
|
|
EP4430167A1
(en)
|
2021-11-10 |
2024-09-18 |
Iovance Biotherapeutics, Inc. |
Methods of expansion treatment utilizing cd8 tumor infiltrating lymphocytes
|
|
WO2023088889A1
(en)
|
2021-11-16 |
2023-05-25 |
Apogenix Ag |
CD137 ligands
|
|
US20250101380A1
(en)
|
2022-01-28 |
2025-03-27 |
Iovance Biotherapeutics, Inc. |
Tumor infiltrating lymphocytes engineered to express payloads
|
|
CA3248034A1
(en)
|
2022-04-15 |
2023-10-19 |
Iovance Biotherapeutics, Inc. |
METHODS FOR EXPANSION OF TIL CELLS BY MEANS OF SPECIFIC CYTOKINE COMBINATIONS AND/OR AKT INHIBITOR TREATMENT
|
|
KR20250034101A
(ko)
|
2022-07-01 |
2025-03-10 |
트랜스진 |
계면활성제-단백질-d 및 tnfsf의 구성원을 포함하는 융합 단백질
|
|
EP4565683A1
(en)
|
2022-08-01 |
2025-06-11 |
Iovance Biotherapeutics, Inc. |
Chimeric costimulatory receptors, chemokine receptors, and the use of same in cellular immunotherapies
|
|
WO2024098024A1
(en)
|
2022-11-04 |
2024-05-10 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof
|
|
WO2024151885A1
(en)
|
2023-01-13 |
2024-07-18 |
Iovance Biotherapeutics, Inc. |
Use of til as maintenance therapy for nsclc patients who achieved pr/cr after prior therapy
|
|
WO2025101484A1
(en)
|
2023-11-06 |
2025-05-15 |
Iovance Biotherapeutics, Inc. |
Treatment of endometrial cancers with tumor infiltrating lymphocyte therapies
|