JP2010531854A - 抗アミロイド剤としてのピレンゼピンおよびその誘導体 - Google Patents
抗アミロイド剤としてのピレンゼピンおよびその誘導体 Download PDFInfo
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- JP2010531854A JP2010531854A JP2010513980A JP2010513980A JP2010531854A JP 2010531854 A JP2010531854 A JP 2010531854A JP 2010513980 A JP2010513980 A JP 2010513980A JP 2010513980 A JP2010513980 A JP 2010513980A JP 2010531854 A JP2010531854 A JP 2010531854A
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Classifications
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Hematology (AREA)
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- Communicable Diseases (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07111491 | 2007-07-02 | ||
| PCT/EP2008/058527 WO2009004038A2 (en) | 2007-07-02 | 2008-07-02 | Therapeutic compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010531854A true JP2010531854A (ja) | 2010-09-30 |
| JP2010531854A5 JP2010531854A5 (enExample) | 2010-11-11 |
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| JP2010513980A Withdrawn JP2010531854A (ja) | 2007-07-02 | 2008-07-02 | 抗アミロイド剤としてのピレンゼピンおよびその誘導体 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20100247688A1 (enExample) |
| EP (1) | EP2173355A2 (enExample) |
| JP (1) | JP2010531854A (enExample) |
| KR (1) | KR20100038424A (enExample) |
| CN (1) | CN101778634A (enExample) |
| AU (1) | AU2008270247A1 (enExample) |
| BR (1) | BRPI0812849A2 (enExample) |
| CA (1) | CA2691844A1 (enExample) |
| IL (1) | IL202768A0 (enExample) |
| MX (1) | MX2009014126A (enExample) |
| NZ (1) | NZ582314A (enExample) |
| RU (1) | RU2010103105A (enExample) |
| WO (1) | WO2009004038A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012153796A1 (ja) * | 2011-05-10 | 2012-11-15 | 協和発酵キリン株式会社 | ピリミドジアゼピノン化合物 |
| JP2023544224A (ja) * | 2020-09-22 | 2023-10-20 | キャスリーン、イー．クラレンス－スミス | ヒト低コリン作動性障害の処置のための医薬の組合せ |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2387405A2 (en) | 2009-01-13 | 2011-11-23 | ProteoSys AG | Pirenzepine as an agent in cancer treatment |
| WO2013068592A1 (en) * | 2011-11-10 | 2013-05-16 | Fondation Jerome Lejeune | Inhibitors of cystathionine beta synthase to reduce the neurotoxic overproduction of endogenous hydrogen sulfide |
| CN116635034A (zh) * | 2020-09-22 | 2023-08-22 | K·E·克拉伦斯-史密斯 | 用于治疗人低胆碱能障碍的药物组合 |
| WO2023137098A1 (en) * | 2022-01-16 | 2023-07-20 | Winsantor, Inc. | Compositions and methods for improving sexual sensory disorders |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1795183B1 (de) * | 1968-08-20 | 1972-07-20 | Thomae Gmbh Dr K | 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel |
| DE3818299A1 (de) * | 1988-05-30 | 1989-12-07 | Thomae Gmbh Dr K | Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE4112014A1 (de) * | 1991-04-12 | 1992-10-15 | Thomae Gmbh Dr K | Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel zur behandlung von erkrankungen des zentralnervensystems und zur foerderung der cerebralen durchblutung |
| KR20070033032A (ko) * | 2004-07-16 | 2007-03-23 | 프로테오시스 악티엔게젤샤프트 | 세포보호제로서 ｐａｒｐ 및 ｓｉｒ 조절 활성을 갖는무스카린 길항제 |
| JP2009501176A (ja) * | 2005-07-12 | 2009-01-15 | アボット ゲーエムベーハー ウント カンパニー カーゲー | グリコーゲンシンターゼキナーゼ３阻害薬としてのピリダジン化合物 |
-
2008
- 2008-07-02 WO PCT/EP2008/058527 patent/WO2009004038A2/en not_active Ceased
- 2008-07-02 EP EP08774661A patent/EP2173355A2/en not_active Withdrawn
- 2008-07-02 CA CA002691844A patent/CA2691844A1/en not_active Abandoned
- 2008-07-02 KR KR1020107002421A patent/KR20100038424A/ko not_active Withdrawn
- 2008-07-02 RU RU2010103105/15A patent/RU2010103105A/ru not_active Application Discontinuation
- 2008-07-02 JP JP2010513980A patent/JP2010531854A/ja not_active Withdrawn
- 2008-07-02 US US12/667,445 patent/US20100247688A1/en not_active Abandoned
- 2008-07-02 BR BRPI0812849-9A2A patent/BRPI0812849A2/pt not_active IP Right Cessation
- 2008-07-02 CN CN200880103247A patent/CN101778634A/zh active Pending
- 2008-07-02 MX MX2009014126A patent/MX2009014126A/es not_active Application Discontinuation
- 2008-07-02 NZ NZ582314A patent/NZ582314A/en not_active IP Right Cessation
- 2008-07-02 AU AU2008270247A patent/AU2008270247A1/en not_active Abandoned
-
2009
- 2009-12-16 IL IL202768A patent/IL202768A0/en unknown
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012153796A1 (ja) * | 2011-05-10 | 2012-11-15 | 協和発酵キリン株式会社 | ピリミドジアゼピノン化合物 |
| JPWO2012153796A1 (ja) * | 2011-05-10 | 2014-07-31 | 協和発酵キリン株式会社 | ピリミドジアゼピノン化合物 |
| US9453021B2 (en) | 2011-05-10 | 2016-09-27 | Kyowa Hakko Kirin Co., Ltd. | Pyrimidodiazepinone compound |
| JP2023544224A (ja) * | 2020-09-22 | 2023-10-20 | キャスリーン、イー．クラレンス－スミス | ヒト低コリン作動性障害の処置のための医薬の組合せ |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009004038A8 (en) | 2010-03-11 |
| WO2009004038A2 (en) | 2009-01-08 |
| BRPI0812849A2 (pt) | 2014-12-09 |
| RU2010103105A (ru) | 2011-08-10 |
| MX2009014126A (es) | 2010-03-29 |
| WO2009004038A3 (en) | 2009-11-26 |
| EP2173355A2 (en) | 2010-04-14 |
| CA2691844A1 (en) | 2009-01-08 |
| NZ582314A (en) | 2012-04-27 |
| KR20100038424A (ko) | 2010-04-14 |
| CN101778634A (zh) | 2010-07-14 |
| IL202768A0 (en) | 2010-06-30 |
| AU2008270247A1 (en) | 2009-01-08 |
| AU2008270247A2 (en) | 2010-01-28 |
| US20100247688A1 (en) | 2010-09-30 |
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