IL202768A0 - Pirenzepine and derivatives thereof as anti-amyloid agents - Google Patents

Pirenzepine and derivatives thereof as anti-amyloid agents

Info

Publication number
IL202768A0
IL202768A0 IL202768A IL20276809A IL202768A0 IL 202768 A0 IL202768 A0 IL 202768A0 IL 202768 A IL202768 A IL 202768A IL 20276809 A IL20276809 A IL 20276809A IL 202768 A0 IL202768 A0 IL 202768A0
Authority
IL
Israel
Prior art keywords
pirenzepine
derivatives
amyloid agents
amyloid
agents
Prior art date
Application number
IL202768A
Other languages
English (en)
Original Assignee
Ac Immune Sa
Proteosys Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ac Immune Sa, Proteosys Ag filed Critical Ac Immune Sa
Publication of IL202768A0 publication Critical patent/IL202768A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Obesity (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL202768A 2007-07-02 2009-12-16 Pirenzepine and derivatives thereof as anti-amyloid agents IL202768A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07111491 2007-07-02
PCT/EP2008/058527 WO2009004038A2 (en) 2007-07-02 2008-07-02 Therapeutic compound

Publications (1)

Publication Number Publication Date
IL202768A0 true IL202768A0 (en) 2010-06-30

Family

ID=40020257

Family Applications (1)

Application Number Title Priority Date Filing Date
IL202768A IL202768A0 (en) 2007-07-02 2009-12-16 Pirenzepine and derivatives thereof as anti-amyloid agents

Country Status (13)

Country Link
US (1) US20100247688A1 (enExample)
EP (1) EP2173355A2 (enExample)
JP (1) JP2010531854A (enExample)
KR (1) KR20100038424A (enExample)
CN (1) CN101778634A (enExample)
AU (1) AU2008270247A1 (enExample)
BR (1) BRPI0812849A2 (enExample)
CA (1) CA2691844A1 (enExample)
IL (1) IL202768A0 (enExample)
MX (1) MX2009014126A (enExample)
NZ (1) NZ582314A (enExample)
RU (1) RU2010103105A (enExample)
WO (1) WO2009004038A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2387405A2 (en) 2009-01-13 2011-11-23 ProteoSys AG Pirenzepine as an agent in cancer treatment
ES2693152T3 (es) * 2011-05-10 2018-12-07 Kyowa Hakko Kirin Co., Ltd. Compuesto de pirimido-diazepinona
WO2013068592A1 (en) * 2011-11-10 2013-05-16 Fondation Jerome Lejeune Inhibitors of cystathionine beta synthase to reduce the neurotoxic overproduction of endogenous hydrogen sulfide
CN116635034A (zh) * 2020-09-22 2023-08-22 K·E·克拉伦斯-史密斯 用于治疗人低胆碱能障碍的药物组合
CA3192987A1 (en) * 2020-09-22 2022-03-31 Kathleen E. Clarence-Smith Pharmaceutical combination for the treatment of human hypocholinergic disorders
WO2023137098A1 (en) * 2022-01-16 2023-07-20 Winsantor, Inc. Compositions and methods for improving sexual sensory disorders

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795183B1 (de) * 1968-08-20 1972-07-20 Thomae Gmbh Dr K 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel
DE3818299A1 (de) * 1988-05-30 1989-12-07 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE4112014A1 (de) * 1991-04-12 1992-10-15 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel zur behandlung von erkrankungen des zentralnervensystems und zur foerderung der cerebralen durchblutung
EP1781300A1 (en) * 2004-07-16 2007-05-09 ProteoSys AG Muscarinic antagonists with parp and sir modulatng activity as agents for inflammatory diseases
MX2008000461A (es) * 2005-07-12 2008-03-10 Abbott Gmbh & Co Kg Compuestos de piridazina como inhibidores de la glucogeno sintasa cinasa 3.

Also Published As

Publication number Publication date
US20100247688A1 (en) 2010-09-30
JP2010531854A (ja) 2010-09-30
KR20100038424A (ko) 2010-04-14
WO2009004038A2 (en) 2009-01-08
BRPI0812849A2 (pt) 2014-12-09
AU2008270247A1 (en) 2009-01-08
NZ582314A (en) 2012-04-27
MX2009014126A (es) 2010-03-29
CA2691844A1 (en) 2009-01-08
RU2010103105A (ru) 2011-08-10
WO2009004038A3 (en) 2009-11-26
AU2008270247A2 (en) 2010-01-28
EP2173355A2 (en) 2010-04-14
CN101778634A (zh) 2010-07-14
WO2009004038A8 (en) 2010-03-11

Similar Documents

Publication Publication Date Title
IL211042A0 (en) Imidazopyridin-2-one derivatives and uses thereof
PT2114900T (pt) Compostos à base de tiopirimidina e as suas utilizações
IL205571A0 (en) 4-pyrazolyl-n-arylpyrimidin-2-amines and 4-pyrazolyl-n-heteroarylpyrimidin
ZA201001300B (en) Antigen-asjuvant compositions and methods
ZA201103635B (en) Azaquinolinone derivatives and uses thereof
GB0701426D0 (en) Compounds and their use
IL207384A0 (en) Oligopeptidic compounds and uses thereof
SI2122095T1 (sl) Dušilnik
EP2207420A4 (en) ANTIGLIFERING METHOD AND COMPOSITIONS
GB0721291D0 (en) Methods and compositions
GB0719526D0 (en) Compositions and methods
EP2170874A4 (en) NEW COMPOUNDS AND THEIR USE
ZA201000357B (en) 2-Azetidinemethaneamines and 2-pyrrolidinemethaneamines as Taar-Ligands
IL208824A0 (en) Iminopyridine derivative and use thereof
IL205308A0 (en) Compounds and methods
EP2274294A4 (en) 5-DIMETHOXY FUMAGILLOL AND ITS DERIVATIVES
IL206951A0 (en) 3-alkyl-piperazine derivatives and uses thereof
GB0708445D0 (en) Compounds and uses thereof
GB0707069D0 (en) Methods and uses
EP2168951A4 (en) AZOLYLMETHYLIDENHYDRAZINE DERIVATIVE AND ITS USE
GB0703405D0 (en) Eco-hat
GB0711398D0 (en) Substituted organpolysiloxanes and uses thereof
IL206950A0 (en) Aminopiperidinyl derivatives and uses thereof
IL200459A0 (en) Alpha-halo-and alpha-alkyl-cyclopropylcarboxy compounds and uses thereof
HU0600910D0 (en) Torsion flagpole