JP2012526844A5 - - Google Patents
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- JP2012526844A5 JP2012526844A5 JP2012511013A JP2012511013A JP2012526844A5 JP 2012526844 A5 JP2012526844 A5 JP 2012526844A5 JP 2012511013 A JP2012511013 A JP 2012511013A JP 2012511013 A JP2012511013 A JP 2012511013A JP 2012526844 A5 JP2012526844 A5 JP 2012526844A5
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- JP
- Japan
- Prior art keywords
- nifedipine
- composition
- item
- nitrosonifedipine
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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| WO2006021954A2 (en) | 2004-08-23 | 2006-03-02 | Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science | Peptide inhibitors for mediating stress responses |
| DK1937244T3 (en) | 2005-09-30 | 2018-10-29 | Io Therapeutics Llc | : CANCER TREATMENT WITH SPECIFIC RXR AGONISTS |
| WO2012160563A2 (en) * | 2011-05-23 | 2012-11-29 | Yeda Research And Development Co. Ltd. | Use of akt phosphorylation as a biomarker for prognosing neurodegenerative diseases and treating same |
| WO2013022953A2 (en) * | 2011-08-08 | 2013-02-14 | Eugenia Wang | Biomarker for alzheimer's disease and/or mild cognitively impairment, and use thereof |
| US10653650B2 (en) | 2011-12-13 | 2020-05-19 | Io Therapeutics, Inc. | Treatment of diseases by concurrently eliciting remyelination effects and immunomodulatory effects using selective RXR agonists |
| CN104114171A (zh) | 2011-12-13 | 2014-10-22 | Io治疗公司 | 使用rxr激动剂的自身免疫紊乱的治疗 |
| RU2015101100A (ru) * | 2012-06-15 | 2016-08-10 | Фаундейшн Фор Байомедикал Рисерч Энд Инновейшн | Профилактическое и/или терапевтическое средство для умеренного когнитивного нарушения |
| US8901305B2 (en) * | 2012-07-31 | 2014-12-02 | Bristol-Myers Squibb Company | Aryl lactam kinase inhibitors |
| US20150045353A1 (en) * | 2013-08-09 | 2015-02-12 | Neurogenetic Pharmaceuticals, Inc. | Formulations containing gamma secretase modulators, methods for preparation and delivery thereof |
| MX364892B (es) | 2015-10-31 | 2019-05-10 | Io Therapeutics Inc | Tratamiento de trastornos del sistema nervioso utilizando combinaciones de agonistas de rxr y hormonas tiroideas. |
| EP3426302B1 (en) | 2016-03-10 | 2022-12-14 | IO Therapeutics, Inc. | Treatment of autoimmune diseases with combinations of rxr agonists and thyroid hormones |
| DK3426303T3 (da) | 2016-03-10 | 2022-09-19 | Io Therapeutics Inc | Behandling af muskellidelser med kombinationer af rxr-agonister og thyroideahormoner |
| EP3684348A4 (en) * | 2017-09-20 | 2021-08-18 | IO Therapeutics, Inc. | TREATMENT OF DISEASE WITH SELECTIVE RXR AGONIST ESTERS |
| US10966950B2 (en) | 2019-06-11 | 2021-04-06 | Io Therapeutics, Inc. | Use of an RXR agonist in treating HER2+ cancers |
| JP2024543621A (ja) | 2021-12-07 | 2024-11-21 | アイオー セラピューティクス インコーポレイテッド | Ｈｅｒ２＋がんの治療におけるｒｘｒアゴニストおよびタキサンの使用 |
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| DE2126533A1 (de) * | 1971-05-28 | 1972-12-14 | Merck Patent Gmbh, 6100 Darmstadt | Verfahren zur Herstellung pharma zeutischer Zubereitungen |
| DE4342196A1 (de) * | 1993-12-10 | 1995-06-14 | Bayer Ag | Neue 4-Phenyl-substituierte 1,4-Dihydropyridine |
| IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US5073543A (en) * | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| IT1229203B (it) * | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
| US5120548A (en) * | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5733566A (en) * | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| US5580578A (en) * | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| IT1270594B (it) * | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| ATE548351T1 (de) * | 1996-01-29 | 2012-03-15 | Us Of America Represented By The Secretary Dept Of Health And Human Services | Dihydropyridin-pyridin-, benzopyranon- und triazolochinazolin-derivate, deren herstellung und verwendung als adenosinrezeptor-antagonisten |
| AU2794199A (en) * | 1998-02-26 | 1999-09-15 | Robertas Bunevicius | Thyroid hormone replacement using sustained release triiodothyronine |
| EP1069918A4 (en) * | 1998-04-08 | 2002-02-20 | Univ Oregon Health Sciences | ACTIVATION OF GALLIUM CELL FIXATION |
| ATE437641T1 (de) * | 2003-05-15 | 2009-08-15 | Roskamp Res Llc | Verfahren zur herstellung von medikamenten zur verringerung der amyloid-abscheidung, amyloid- neurotoxizität und mikrogliosis |
| EP1952824A1 (en) * | 2003-11-21 | 2008-08-06 | Memory Pharmaceuticals Corporation | Compositions and methods of treatment using L-type calcium channel blockers and cholinesterase inhibitors |
| BRPI0518151A2 (pt) * | 2004-10-13 | 2009-06-16 | Ablynx Nv | polipetìdeos contra amiloide-beta, ácido nucléico que codifica tal polipetìdeo, composição compreendendo tal polipetìdeo, método para produzir um polipetìdeo e uso do mesmo |
| EP1874311B1 (en) * | 2005-04-15 | 2011-10-05 | Research & Innovation S.p.A. | A method for preventing, delaying or reverting abnormal amyloid deposition |
| JP2008539255A (ja) * | 2005-04-26 | 2008-11-13 | マイクロビア インコーポレーテッド | 高コレステロール血症のための４−ビアリーリル−１−フェニルアゼチジン−２−オングルクロニド誘導体 |
| JP2007091664A (ja) * | 2005-09-29 | 2007-04-12 | Univ Of Tokushima | 細胞膜保護剤 |
| JP5043677B2 (ja) * | 2005-12-02 | 2012-10-10 | 持田製薬株式会社 | アルツハイマー型認知症予防・治療剤 |
| WO2007112288A2 (en) * | 2006-03-23 | 2007-10-04 | Mount Sinai School Of Medicine | Cardiovascular composition and use the same for the treatment of alzheimers disease |
| EP2018186A2 (en) * | 2006-04-11 | 2009-01-28 | Ordway Research Institute, Inc. | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof |
| JP2009073759A (ja) * | 2007-09-20 | 2009-04-09 | Univ Of Tokushima | Ｉｃａｍ−１発現抑制剤 |
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- 2010-05-13 AU AU2010249015A patent/AU2010249015A1/en not_active Abandoned
- 2010-05-13 CA CA2761298A patent/CA2761298A1/en not_active Abandoned
- 2010-05-13 EP EP10775535A patent/EP2429992A4/en not_active Withdrawn
- 2010-05-13 MX MX2011012015A patent/MX2011012015A/es not_active Application Discontinuation
- 2010-05-13 WO PCT/US2010/034721 patent/WO2010132671A1/en not_active Ceased
- 2010-05-13 JP JP2012511013A patent/JP2012526844A/ja active Pending
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