JP2010531694A - 多孔性芯と緻密な表面層から構成された外科用インプラント - Google Patents
多孔性芯と緻密な表面層から構成された外科用インプラント Download PDFInfo
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- JP2010531694A JP2010531694A JP2010513993A JP2010513993A JP2010531694A JP 2010531694 A JP2010531694 A JP 2010531694A JP 2010513993 A JP2010513993 A JP 2010513993A JP 2010513993 A JP2010513993 A JP 2010513993A JP 2010531694 A JP2010531694 A JP 2010531694A
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- Prior art keywords
- porous core
- porous
- surgical implant
- core
- biocompatible material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0003—Not used, see subgroups
- A61C8/0004—Consolidating natural teeth
- A61C8/0006—Periodontal tissue or bone regeneration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0018—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the shape
- A61C8/0027—Frames
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B22—CASTING; POWDER METALLURGY
- B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
- B22F7/00—Manufacture of composite layers, workpieces, or articles, comprising metallic powder, by sintering the powder, with or without compacting wherein at least one part is obtained by sintering or compression
- B22F7/002—Manufacture of composite layers, workpieces, or articles, comprising metallic powder, by sintering the powder, with or without compacting wherein at least one part is obtained by sintering or compression of porous nature
- B22F7/004—Manufacture of composite layers, workpieces, or articles, comprising metallic powder, by sintering the powder, with or without compacting wherein at least one part is obtained by sintering or compression of porous nature comprising at least one non-porous part
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- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22C—ALLOYS
- C22C1/00—Making non-ferrous alloys
- C22C1/08—Alloys with open or closed pores
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- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/30004—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
- A61F2002/30011—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis differing in porosity
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- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30576—Special structural features of bone or joint prostheses not otherwise provided for with extending fixation tabs
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- B22F2998/00—Supplementary information concerning processes or compositions relating to powder metallurgy
Abstract
【解決手段】 緻密シェルは多孔性芯部を軟組織の内部成長から遮蔽する。多孔性芯部は開放相互連結細孔を含む。本発明は外科用インプラントを製造する方法にも関係し、それは多孔性芯部を製造し、粘稠な懸濁液を多孔性芯部の表面の部分の上に付与し、熱処理を適用する工程を含む。
【選択図】 図2
Description
1. Garrett Ryan,Abhay Pandit,Dimitrios Panagiotis Apatsidis,“Fabrication methods of porous metals for use in orthopaedic applications”,Biomaterials 27(2006),pp. 2651−2670
2. P.Habibovic,J.Li,C.M.vanderValk,G.Meijer,P.Layrolle,C.A.Van Blitterswijk,K.de Groot,Biomaterials 26(2005),pp.23−36
50gのTi粉末(Cerac T−1147)、
14.83gのH2O、
0.03gのBenecel、
0.667gのゼラチン、
0.85gのtargon 1128、
0.15gの消泡剤。
この粘稠な懸濁液は多孔性芯部の表面の上に塗布され、噴霧されまたはブラシ塗りされ、表面細孔の閉鎖をもたらす。
Claims (13)
- 多孔性生物適合性材料から作られた多孔性芯部(11)と生物適合性材料から作られた緻密シェル(12)とを含む外科用インプラント(10)において、前記シェルが、前記生物軟組織の多孔性芯部中への内部成長を防ぐために、多孔性芯部と生物軟組織との間に界面を形成するように構成された多孔性芯部の表面の部分の上に設けられることを特徴とする外科用インプラント。
- 緻密シェルが200μm〜1000μm、好ましくは300μm〜500μmの範囲の厚さを持つことを特徴とする請求項1に記載の外科用インプラント。
- 多孔性芯部(11)が多孔性チタンまたは多孔性Ti合金から作られ、緻密シェル(12)がチタンまたはTi合金から作られることを特徴とする請求項1または2に記載の外科用インプラント。
- 多孔性芯部(11)が多孔性セラミック材料、特にリン酸カルシウムから作られ、緻密シェル(12)がセラミック材料、特にリン酸カルシウムから作られることを特徴とする請求項1または2に記載の外科用インプラント。
- 多孔性芯部(11)が開放相互連結細孔を含むことを特徴とする請求項1〜4のいずれか一つに記載の外科用インプラント。
- 多孔性芯が理論密度の25%〜95%、好ましくは理論密度の60%〜90%の範囲にある多孔度を持つことを特徴とする請求項1〜5のいずれか一つに記載の外科用インプラント。
- 外科用インプラントの骨への取り付けのための開口(42)を備えたプレートまたはストリップ(41)を含むことを特徴とする請求項1〜6のいずれか一つに記載の外科用インプラント。
- 一つまたはそれより多い歯冠を固定するための手段(32)を含むことを特徴とする請求項1〜7のいずれか一つに記載の外科用インプラント。
- 以下の工程を含むことを特徴とする外科用インプラントを製造する方法:
− 第一生物適合性材料の多孔性芯部(11)を製造する、
− 第一生物適合性材料または第二生物適合性材料の粉末を含む懸濁液を多孔性芯部の表面の少なくとも部分の上に付与して被覆された芯部を得る、そして
− この被覆された芯部に熱処理を適用する。 - 第一生物適合性材料がチタンまたはTi合金であり、第二生物適合性材料がチタンまたはTi合金であることを特徴とする請求項9に記載の方法。
- 多孔性芯部を製造する工程が、ゲル鋳造技術、3D繊維付着技術または迅速プロトタイピング技術を使用して多孔性芯部を製造することを含むことを特徴とする請求項9または10に記載の方法。
- 懸濁液を付与する工程の前に多孔性芯部の表面の前記部分を決定する工程をさらに含み、表面の前記部分が生物軟組織による侵入から遮蔽されるように構成されていることを特徴とする請求項9〜11のいずれか一つに記載の方法。
- 懸濁液を付与する工程が多孔性芯部の表面の部分の上に懸濁液を塗布し、噴霧し、ブラシ塗りし、またはテープ鋳造することを含むことを特徴とする請求項9〜12のいずれか一つに記載の方法。
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EP07111662 | 2007-07-03 | ||
PCT/EP2008/058625 WO2009004070A1 (en) | 2007-07-03 | 2008-07-03 | Surgical implant composed of a porous core and a dense surface layer |
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- 2008-07-03 JP JP2010513993A patent/JP5318864B2/ja not_active Expired - Fee Related
- 2008-07-03 EP EP08774737A patent/EP2173280A1/en not_active Withdrawn
- 2008-07-03 CA CA2692498A patent/CA2692498C/en not_active Expired - Fee Related
- 2008-07-03 WO PCT/EP2008/058625 patent/WO2009004070A1/en active Application Filing
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JP2015507491A (ja) * | 2011-12-22 | 2015-03-12 | アリ、 モハメド イクバルALI, Mohamed Ikbal | 骨成長を増進するためのデバイスおよび方法 |
JP2017536216A (ja) * | 2014-10-10 | 2017-12-07 | トゥロワデセラム | 骨欠損の補填用の合成ブロック及びその製造方法 |
JP2019155121A (ja) * | 2014-10-10 | 2019-09-19 | エス.ア.エス. スリーディーセラム − シントー | 骨欠損の補填用の合成ブロック及びその製造方法 |
US10639156B2 (en) | 2014-10-10 | 2020-05-05 | S.A.S. 3DCeram-Sinto | Synthetic block intended for filling in a bone defect and method for manufacturing same |
JP7059223B2 (ja) | 2014-10-10 | 2022-04-25 | エス.ア.エス. スリーディーセラム - シントー | 骨欠損の補填用の合成ブロック及びその製造方法 |
KR20190077778A (ko) * | 2017-12-26 | 2019-07-04 | 건양대학교산학협력단 | 솔리드 면이 형성된 다공성 오그먼트 |
KR20190077787A (ko) * | 2017-12-26 | 2019-07-04 | 건양대학교산학협력단 | 다공성 오그먼트 |
KR102014166B1 (ko) * | 2017-12-26 | 2019-08-27 | 건양대학교 산학협력단 | 솔리드 면이 형성된 다공성 오그먼트 |
KR102014195B1 (ko) * | 2017-12-26 | 2019-08-27 | 건양대학교 산학협력단 | 다공성 오그먼트 |
KR20210020316A (ko) * | 2019-08-14 | 2021-02-24 | 연세대학교 산학협력단 | 3d 프린터로 형성된 인공치아 제조틀로 제조된 섬유보강 인공치아 |
KR102247413B1 (ko) | 2019-08-14 | 2021-04-30 | 연세대학교 산학협력단 | 3d 프린터로 형성된 인공치아 제조틀로 제조된 섬유보강 인공치아 |
WO2022074951A1 (ja) * | 2020-10-07 | 2022-04-14 | 国立研究開発法人理化学研究所 | 三次元造形物と、その製造方法および制御プログラム |
Also Published As
Publication number | Publication date |
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CA2692498A1 (en) | 2009-01-08 |
WO2009004070A1 (en) | 2009-01-08 |
US20100256773A1 (en) | 2010-10-07 |
JP5318864B2 (ja) | 2013-10-16 |
EP2173280A1 (en) | 2010-04-14 |
CA2692498C (en) | 2015-09-01 |
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