JP2010531313A5 - - Google Patents

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Publication number
JP2010531313A5
JP2010531313A5 JP2010513710A JP2010513710A JP2010531313A5 JP 2010531313 A5 JP2010531313 A5 JP 2010531313A5 JP 2010513710 A JP2010513710 A JP 2010513710A JP 2010513710 A JP2010513710 A JP 2010513710A JP 2010531313 A5 JP2010531313 A5 JP 2010531313A5
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JP
Japan
Prior art keywords
phenyl
unsubstituted
independently
benzimidazole
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010513710A
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English (en)
Japanese (ja)
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JP2010531313A (ja
JP5492770B2 (ja
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Priority claimed from PCT/EP2008/004639 external-priority patent/WO2009000413A1/en
Publication of JP2010531313A publication Critical patent/JP2010531313A/ja
Publication of JP2010531313A5 publication Critical patent/JP2010531313A5/ja
Application granted granted Critical
Publication of JP5492770B2 publication Critical patent/JP5492770B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010513710A 2007-06-26 2008-06-11 ベンゾイミダゾール及びアザベンゾイミダゾールの位置選択的銅触媒合成 Expired - Fee Related JP5492770B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07290800 2007-06-26
EP07290800.7 2007-06-26
PCT/EP2008/004639 WO2009000413A1 (en) 2007-06-26 2008-06-11 A regioselective copper catalyzed synthesis of benzimidazoles and azabenzimidazoles

Publications (3)

Publication Number Publication Date
JP2010531313A JP2010531313A (ja) 2010-09-24
JP2010531313A5 true JP2010531313A5 (enExample) 2011-07-07
JP5492770B2 JP5492770B2 (ja) 2014-05-14

Family

ID=38646504

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010513710A Expired - Fee Related JP5492770B2 (ja) 2007-06-26 2008-06-11 ベンゾイミダゾール及びアザベンゾイミダゾールの位置選択的銅触媒合成

Country Status (12)

Country Link
US (1) US8735586B2 (enExample)
EP (1) EP2173721B1 (enExample)
JP (1) JP5492770B2 (enExample)
KR (1) KR20100023907A (enExample)
CN (1) CN101687815A (enExample)
AT (1) ATE539063T1 (enExample)
AU (1) AU2008267444A1 (enExample)
BR (1) BRPI0813271A2 (enExample)
CA (1) CA2691857A1 (enExample)
IL (1) IL202823A0 (enExample)
MX (1) MX2009013753A (enExample)
WO (1) WO2009000413A1 (enExample)

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WO2012026766A2 (ko) 2010-08-25 2012-03-01 (주)네오팜 신규한 헤테로고리 화합물 및 이를 이용한 염증성 질환 치료용 조성물
ES2616238T3 (es) 2010-10-06 2017-06-12 Glaxosmithkline Llc, Corporation Service Company Derivados de bencimidazol como inhibidores de PI3 quinasa
JP6001049B2 (ja) 2011-03-31 2016-10-05 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ Ｍｐｓ−１キナーゼ阻害剤としての置換ベンズイミダゾール類
WO2012177852A1 (en) 2011-06-24 2012-12-27 Arqule, Inc Substituted imidazopyridinyl compounds
EP2723741B8 (en) 2011-06-24 2016-09-21 ArQule, Inc. Substituted imidazopyridinyl-aminopyridine compounds
CN104395300A (zh) * 2012-06-22 2015-03-04 住友化学株式会社 稠合杂环化合物
CN102924460B (zh) * 2012-11-05 2015-12-16 南京师范大学 一种4H-吡咯并[1,2-a]苯并咪唑衍生物及其合成方法和应用
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
WO2014080291A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Biaryl derivatives as bromodomain inhibitors
US9271978B2 (en) 2012-12-21 2016-03-01 Zenith Epigenetics Corp. Heterocyclic compounds as bromodomain inhibitors
CN103130811B (zh) * 2013-03-11 2015-02-25 河南师范大学 一种5,6-二氢吡唑并[1,5-c]喹唑啉类化合物的合成方法
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WO2014151367A1 (en) 2013-03-15 2014-09-25 Janssen Pharmaceutica Nv 1,2,5-substituted benzimidazoles as flap modulators
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AU2014298051B2 (en) 2013-07-31 2018-11-15 Zenith Epigenetics Ltd. Novel quinazolinones as bromodomain inhibitors
CA2929858C (en) 2013-11-22 2022-03-29 CL BioSciences LLC Gastrin antagonists (eg yf476, netazepide) for treatment and prevention of osteoporosis
CN103965136B (zh) * 2014-05-07 2016-09-07 苏州波菲特新材料科技有限公司 一种制备n-甲基噻唑啉-2-酮类化合物的方法
WO2016087936A1 (en) 2014-12-01 2016-06-09 Zenith Epigenetics Corp. Substituted pyridinones as bromodomain inhibitors
WO2016087942A1 (en) 2014-12-01 2016-06-09 Zenith Epigenetics Corp. Substituted pyridines as bromodomain inhibitors
CN107207474B (zh) 2014-12-11 2021-05-07 恒翼生物医药科技(上海)有限公司 被取代的杂环作为溴结构域抑制剂
CA2966450A1 (en) 2014-12-17 2016-06-23 Olesya KHARENKO Inhibitors of bromodomains
EP3377493B1 (en) 2015-11-20 2020-04-08 Forma Therapeutics, Inc. Purinones as ubiquitin-specific protease 1 inhibitors
CN106519250A (zh) * 2016-09-29 2017-03-22 辽宁石油化工大学 含氮小分子有机配体调节荧光发射性质的一维链状铜配位聚合物的制备方法
GB201617630D0 (en) 2016-10-18 2016-11-30 Cellcentric Ltd Pharmaceutical compounds
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