JP2010529950A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010529950A5 JP2010529950A5 JP2010507772A JP2010507772A JP2010529950A5 JP 2010529950 A5 JP2010529950 A5 JP 2010529950A5 JP 2010507772 A JP2010507772 A JP 2010507772A JP 2010507772 A JP2010507772 A JP 2010507772A JP 2010529950 A5 JP2010529950 A5 JP 2010529950A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- subject
- immunoreactive
- molecule
- monoclonal antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims description 34
- 206010028980 Neoplasm Diseases 0.000 claims description 17
- 239000000203 mixture Substances 0.000 claims description 17
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 10
- 201000011510 cancer Diseases 0.000 claims description 8
- 239000002246 antineoplastic agent Substances 0.000 claims description 7
- 239000012634 fragment Substances 0.000 claims description 7
- 229940127089 cytotoxic agent Drugs 0.000 claims description 5
- 241001465754 Metazoa Species 0.000 claims description 4
- 238000001959 radiotherapy Methods 0.000 claims description 4
- 210000001124 body fluid Anatomy 0.000 claims description 3
- 239000010839 body fluid Substances 0.000 claims description 3
- 108060003951 Immunoglobulin Proteins 0.000 claims description 2
- 235000014633 carbohydrates Nutrition 0.000 claims description 2
- 238000003745 diagnosis Methods 0.000 claims description 2
- 238000003018 immunoassay Methods 0.000 claims description 2
- 102000018358 immunoglobulin Human genes 0.000 claims description 2
- 239000007787 solid Substances 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 230000028993 immune response Effects 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 2
- 125000000837 carbohydrate group Chemical group 0.000 claims 1
- 230000002942 anti-growth Effects 0.000 description 2
- 231100000599 cytotoxic agent Toxicity 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 239000003102 growth factor Substances 0.000 description 2
- 230000004807 localization Effects 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 101710112752 Cytotoxin Proteins 0.000 description 1
- 230000003302 anti-idiotype Effects 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000002254 cytotoxic agent Substances 0.000 description 1
- 239000002619 cytotoxin Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000002163 immunogen Effects 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91790607P | 2007-05-14 | 2007-05-14 | |
| US60/917,906 | 2007-05-14 | ||
| US4402808P | 2008-04-10 | 2008-04-10 | |
| US61/044,028 | 2008-04-10 | ||
| PCT/CA2008/000932 WO2008138139A1 (en) | 2007-05-14 | 2008-05-14 | Carbohydrate-containing pan cancer marker |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010529950A JP2010529950A (ja) | 2010-09-02 |
| JP2010529950A5 true JP2010529950A5 (enExample) | 2011-06-30 |
| JP5683948B2 JP5683948B2 (ja) | 2015-03-11 |
Family
ID=40001646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010507772A Active JP5683948B2 (ja) | 2007-05-14 | 2008-05-14 | 糖を含有する全ての（ｐａｎ）癌のマーカー |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8143373B2 (enExample) |
| EP (1) | EP2155250B1 (enExample) |
| JP (1) | JP5683948B2 (enExample) |
| CN (1) | CN102014955A (enExample) |
| AU (1) | AU2008250953B2 (enExample) |
| CA (1) | CA2687403A1 (enExample) |
| WO (1) | WO2008138139A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012006718A1 (en) * | 2010-07-14 | 2012-01-19 | Vancouver Biotech Ltd. | Carbohydrate hapten-based anti-cancer vaccines and antibody drugs |
| CN102901817A (zh) * | 2011-07-27 | 2013-01-30 | 北京大学 | Non-B Ig单抗RP215在细胞增殖、迁移及干细胞研究中的应用 |
| US8974786B2 (en) | 2012-06-13 | 2015-03-10 | Vancouver Biotech Ltd. | Humanized antibodies to CA215 |
| CN105353132B (zh) * | 2015-11-13 | 2018-04-10 | 北京大学 | non B‑s IgG作为干/祖细胞标志物的应用 |
| US11447562B2 (en) | 2017-01-01 | 2022-09-20 | Chi-Yu Gregory Lee | RP215 chimeric antigen receptor construct and methods of making and using same |
| CN108484777B (zh) * | 2017-03-31 | 2022-07-12 | 李吉祐 | 人源化rp215单克隆抗体的嵌合抗原受体构建体及核酸分子与应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| AU6031090A (en) * | 1989-07-31 | 1991-03-11 | University Of British Columbia, The | Monoclonal antibodies against a tumor-associated antigen |
| US6312924B1 (en) * | 1999-03-18 | 2001-11-06 | Zymogenetics, Inc. | Murine interferon-α |
| US6908612B2 (en) * | 1999-10-08 | 2005-06-21 | University Of Maryland Biotechnology Institute | Virus coat protein/receptor chimeras and methods of use |
| CA2481829A1 (en) * | 2002-04-09 | 2003-10-16 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Anti-idiotype anti-cea antibody molecules and its use as cancer vaccine |
| US20080081045A1 (en) * | 2003-10-14 | 2008-04-03 | Biomira, Inc. | Combination Therapy for Cancer |
-
2008
- 2008-05-14 AU AU2008250953A patent/AU2008250953B2/en not_active Ceased
- 2008-05-14 WO PCT/CA2008/000932 patent/WO2008138139A1/en not_active Ceased
- 2008-05-14 US US12/599,284 patent/US8143373B2/en active Active - Reinstated
- 2008-05-14 EP EP08757092.5A patent/EP2155250B1/en active Active
- 2008-05-14 JP JP2010507772A patent/JP5683948B2/ja active Active
- 2008-05-14 CN CN200880001243XA patent/CN102014955A/zh active Pending
- 2008-05-14 CA CA002687403A patent/CA2687403A1/en not_active Abandoned
-
2012
- 2012-03-22 US US13/427,109 patent/US20120177636A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6622363B2 (ja) | 抗リポアラビノマンナン抗体及び当該抗体を用いた抗酸菌症のイムノアッセイ | |
| JP6539709B2 (ja) | 潜在的有害作用リスクのある患者にＣＤ１９ｘＣＤ３二特異性抗体を投与するための投薬レジメン | |
| US20230220073A1 (en) | Ror1 antibodies | |
| JP2024161509A5 (enExample) | ||
| US9758586B2 (en) | Chimeric rabbit/human ROR1 antibodies | |
| CN110891972B (zh) | 对ror1和cd3的双特异性抗体 | |
| JP2019523651A5 (enExample) | ||
| WO2013188864A4 (en) | Anti-cd22 anti-idiotypic antibodies and uses thereof | |
| JP2010529950A5 (enExample) | ||
| JP2014531409A5 (enExample) | ||
| Schuster et al. | Immunotherapy with the trifunctional anti‐CD 20 x anti‐CD 3 antibody FBTA 05 (Lymphomun) in paediatric high‐risk patients with recurrent CD 20‐positive B cell malignancies | |
| JP2014502253A5 (enExample) | ||
| JP2019520034A5 (enExample) | ||
| JP2008545145A5 (enExample) | ||
| RU2016135962A (ru) | Выделенное антитело, способ его получения, выделенная нуклеиновая кислота, экспрессионная кассета, клетка-хозяин, фармацевтический и диагностический препараты, способ лечения больного, подверженного риску или страдающего от инфекции E.COLI, и способ диагностики определения инфекций E.COLI | |
| JP2020534012A5 (enExample) | ||
| EP3519827A1 (en) | Methods for treating cancer with bavituximab based on levels of 2-glycoprotein 1, and assays therefor | |
| WO2023076881A1 (en) | Single domain antibodies targeting the s2 subunit of sars-cov-2 spike protein | |
| PT2432804E (pt) | Anticorpos ou seus fragmentos direcionados contra um epítopo de staphylococcus aureus de isaa ou isab | |
| JP5683948B2 (ja) | 糖を含有する全ての（ｐａｎ）癌のマーカー | |
| Siebert et al. | Validated detection of human anti-chimeric immune responses in serum of neuroblastoma patients treated with ch14. 18/CHO | |
| JP7366353B2 (ja) | 抗インドキシル硫酸の単離されたモノクローナル抗体及び／又はその抗原結合断片の組成物及びその用途 | |
| EP3423498A1 (en) | Clinical assessment of m-protein response in multiple myeloma | |
| JP2012503634A5 (enExample) | ||
| RU2774194C2 (ru) | Антитела, направленные на эпитопы, расположенные в области 160-200 аминокислотных оснований белка PRAME человека, и их применение |