JP2010529146A5 - - Google Patents

Info

Publication number

JP2010529146A5

JP2010529146A5 JP2010511401A JP2010511401A JP2010529146A5 JP 2010529146 A5 JP2010529146 A5 JP 2010529146A5 JP 2010511401 A JP2010511401 A JP 2010511401A JP 2010511401 A JP2010511401 A JP 2010511401A JP 2010529146 A5 JP2010529146 A5 JP 2010529146A5

Authority

JP

Japan

Prior art keywords

formula

composition

compound

human subject

salt

Prior art date

2008-06-09

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
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• 238000000034 method Methods 0.000 claims description 26
• 239000000203 mixture Substances 0.000 claims description 17
• 244000078703 ectoparasite Species 0.000 claims description 7
• 150000001875 compounds Chemical class 0.000 claims 13
• 150000003839 salts Chemical class 0.000 claims 12
• 238000011200 topical administration Methods 0.000 claims 6
• 239000002552 dosage form Substances 0.000 claims 4
• 239000007788 liquid Substances 0.000 claims 4
• 239000008194 pharmaceutical composition Substances 0.000 claims 4
• 239000007787 solid Substances 0.000 claims 4
• 241000254062 Scarabaeidae Species 0.000 claims 3
• LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims 3
• 241000238421 Arthropoda Species 0.000 claims 1
• 241000283690 Bos taurus Species 0.000 claims 1
• 241000282472 Canis lupus familiaris Species 0.000 claims 1
• 241000283707 Capra Species 0.000 claims 1
• 241000283086 Equidae Species 0.000 claims 1
• 241000282326 Felis catus Species 0.000 claims 1
• 241000257226 Muscidae Species 0.000 claims 1
• 241001494479 Pecora Species 0.000 claims 1
• 241000282887 Suidae Species 0.000 claims 1
• 238000007598 dipping method Methods 0.000 claims 1
• 239000000463 material Substances 0.000 claims 1
• 238000007911 parenteral administration Methods 0.000 claims 1
• 239000000843 powder Substances 0.000 claims 1
• 239000008247 solid mixture Substances 0.000 claims 1
• 241000894007 species Species 0.000 claims 1
• 238000005507 spraying Methods 0.000 claims 1
• 241001465754 Metazoa Species 0.000 description 2
• BNYCHCAYYYRJSH-UHFFFAOYSA-N 1h-pyrazole-5-carboxamide Chemical compound NC(=O)C1=CC=NN1 BNYCHCAYYYRJSH-UHFFFAOYSA-N 0.000 description 1
• -1 4-tert-butylphenyl Chemical group 0.000 description 1
• 241000238876 Acari Species 0.000 description 1
• 241000255925 Diptera Species 0.000 description 1
• BYSATPULTLVQIE-UHFFFAOYSA-N N-[[4-(4-methylphenoxy)phenyl]methyl]-1H-pyrazole-5-carboxamide Chemical compound Cc1ccc(Oc2ccc(CNC(=O)c3ccn[nH]3)cc2)cc1 BYSATPULTLVQIE-UHFFFAOYSA-N 0.000 description 1
• 241001674048 Phthiraptera Species 0.000 description 1
• 241000258242 Siphonaptera Species 0.000 description 1
• DMYHGDXADUDKCQ-UHFFFAOYSA-N fenazaquin Chemical compound C1=CC(C(C)(C)C)=CC=C1CCOC1=NC=NC2=CC=CC=C12 DMYHGDXADUDKCQ-UHFFFAOYSA-N 0.000 description 1
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
• ITKAIUGKVKDENI-UHFFFAOYSA-N pyrimidifen Chemical compound CC1=C(C)C(CCOCC)=CC=C1OCCNC1=NC=NC(CC)=C1Cl ITKAIUGKVKDENI-UHFFFAOYSA-N 0.000 description 1