JP2010524952A5 - - Google Patents

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Publication number
JP2010524952A5
JP2010524952A5 JP2010504191A JP2010504191A JP2010524952A5 JP 2010524952 A5 JP2010524952 A5 JP 2010524952A5 JP 2010504191 A JP2010504191 A JP 2010504191A JP 2010504191 A JP2010504191 A JP 2010504191A JP 2010524952 A5 JP2010524952 A5 JP 2010524952A5
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JP
Japan
Prior art keywords
pharmaceutically acceptable
acceptable salt
compound
alkyl
heteroaryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010504191A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010524952A (ja
JP5635398B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/060366 external-priority patent/WO2008128231A1/en
Publication of JP2010524952A publication Critical patent/JP2010524952A/ja
Publication of JP2010524952A5 publication Critical patent/JP2010524952A5/ja
Application granted granted Critical
Publication of JP5635398B2 publication Critical patent/JP5635398B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010504191A 2007-04-16 2008-04-15 ピリミジン誘導体 Expired - Fee Related JP5635398B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91192107P 2007-04-16 2007-04-16
US60/911,921 2007-04-16
PCT/US2008/060366 WO2008128231A1 (en) 2007-04-16 2008-04-15 Pyrimidine derivatives

Publications (3)

Publication Number Publication Date
JP2010524952A JP2010524952A (ja) 2010-07-22
JP2010524952A5 true JP2010524952A5 (OSRAM) 2011-06-02
JP5635398B2 JP5635398B2 (ja) 2014-12-03

Family

ID=39854302

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010504191A Expired - Fee Related JP5635398B2 (ja) 2007-04-16 2008-04-15 ピリミジン誘導体

Country Status (17)

Country Link
US (2) US8349859B2 (OSRAM)
EP (1) EP2154967B9 (OSRAM)
JP (1) JP5635398B2 (OSRAM)
KR (1) KR101424847B1 (OSRAM)
BR (1) BRPI0809715A2 (OSRAM)
CA (1) CA2684470C (OSRAM)
DK (1) DK2154967T5 (OSRAM)
ES (1) ES2465673T3 (OSRAM)
HR (1) HRP20140377T2 (OSRAM)
MX (1) MX2009011199A (OSRAM)
NZ (1) NZ580671A (OSRAM)
PL (1) PL2154967T3 (OSRAM)
PT (1) PT2154967E (OSRAM)
RU (1) RU2455994C2 (OSRAM)
SI (1) SI2154967T1 (OSRAM)
TW (1) TWI484960B (OSRAM)
WO (1) WO2008128231A1 (OSRAM)

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AR074209A1 (es) 2008-11-24 2010-12-29 Boehringer Ingelheim Int Derivados de pirimidina utiles para el tratamiento del cancer
JP2012197231A (ja) * 2009-08-06 2012-10-18 Oncotherapy Science Ltd Ｔｔｋ阻害作用を有するピリジンおよびピリミジン誘導体
US8466155B2 (en) * 2009-10-02 2013-06-18 Boehringer Ingelheim International Gmbh Pyrimidines
CN102070618B (zh) 2009-11-23 2013-08-21 和记黄埔医药（上海）有限公司 一种化合物及其晶体
EP2395001A1 (en) 2010-05-21 2011-12-14 Chemilia AB Novel pyrimidine derivatives
WO2011144742A1 (en) 2010-05-21 2011-11-24 Chemilia Ab Novel pyrimidine derivatives
EP2433636A1 (en) * 2010-09-27 2012-03-28 Medizinische Universität Wien Treatment of Malignant Diseases
US8785467B2 (en) 2010-09-30 2014-07-22 Merck Sharp & Dohme Corp. Alkoxy pyrimidine PDE10 inhibitors
EP2502924A1 (en) 2011-03-24 2012-09-26 Chemilia AB Novel pyrimidine derivatives
EP2688883B1 (en) 2011-03-24 2016-05-18 Noviga Research AB Pyrimidine derivatives
WO2013054351A1 (en) * 2011-08-08 2013-04-18 Cadila Healthcare Limited Heterocyclic compounds
EP2711364A1 (en) 2012-09-21 2014-03-26 Chemilia AB 4-(Indolyl or benzimidazolyl)amino-2-(2-(indol-3-yl)ethyl)aminopyrimidines useful for the treatment of cancer
EP2711365A1 (en) 2012-09-21 2014-03-26 Chemilia AB 4-Indazolylamino-2-(2-(indol-3-yl)ethyl)aminopyrimidines useful for the treatment of cancer
WO2014071378A1 (en) * 2012-11-05 2014-05-08 Nant Holdings Ip, Llc Substituted indol-5-ol derivatives and their therapeutical applications
KR101871561B1 (ko) 2013-03-15 2018-06-27 난트바이오사이언스 인코포레이티드 치환된 인돌-5-올 유도체와 그들의 치료적 용도
CN105601573B (zh) 2014-11-24 2021-07-02 中国科学院上海药物研究所 2-氨基嘧啶类化合物及其药物组合物和应用
RU2701188C2 (ru) * 2015-02-27 2019-09-25 Нэнтбайосайенс, Инк. Производные пиримидина в качестве ингибиторов киназы и их терапевтические применения
US10981899B2 (en) 2016-04-28 2021-04-20 Cornell University Inhibitors of soluble adenylyl cyclase
CN112469713B (zh) * 2019-06-21 2023-09-01 江苏豪森药业集团有限公司 芳基磷氧化物类衍生物抑制剂、其制备方法和应用
CN111004221B (zh) * 2019-12-13 2021-02-02 长治学院 一种嘧啶/苯并咪唑杂合物、制备方法及医药用途
IL303237A (en) * 2020-11-27 2023-07-01 Anrui Biomedical Tech Guangzhou Co Ltd Aminoheteroaryl kinase inhibitors

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