JP2010518030A5 - - Google Patents
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- Publication number
- JP2010518030A5 JP2010518030A5 JP2009548553A JP2009548553A JP2010518030A5 JP 2010518030 A5 JP2010518030 A5 JP 2010518030A5 JP 2009548553 A JP2009548553 A JP 2009548553A JP 2009548553 A JP2009548553 A JP 2009548553A JP 2010518030 A5 JP2010518030 A5 JP 2010518030A5
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- composition
- ester
- dimethyl
- unbranched
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 25
- WTEVQBCEXWBHNA-JXMROGBWSA-N geranial Chemical compound CC(C)=CCC\C(C)=C\C=O WTEVQBCEXWBHNA-JXMROGBWSA-N 0.000 claims 16
- -1 terpene compound Chemical class 0.000 claims 16
- GLZPCOQZEFWAFX-UHFFFAOYSA-N Geraniol Chemical compound CC(C)=CCCC(C)=CCO GLZPCOQZEFWAFX-UHFFFAOYSA-N 0.000 claims 15
- 235000007586 terpenes Nutrition 0.000 claims 12
- 150000002148 esters Chemical class 0.000 claims 9
- 150000003839 salts Chemical class 0.000 claims 9
- WTEVQBCEXWBHNA-UHFFFAOYSA-N Citral Natural products CC(C)=CCCC(C)=CC=O WTEVQBCEXWBHNA-UHFFFAOYSA-N 0.000 claims 8
- 239000012453 solvate Substances 0.000 claims 8
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 claims 7
- 125000004423 acyloxy group Chemical group 0.000 claims 7
- 125000003545 alkoxy group Chemical group 0.000 claims 7
- 125000000217 alkyl group Chemical group 0.000 claims 7
- DZNVIZQPWLDQHI-UHFFFAOYSA-N Citronellyl formate Chemical compound O=COCCC(C)CCC=C(C)C DZNVIZQPWLDQHI-UHFFFAOYSA-N 0.000 claims 6
- QMVPMAAFGQKVCJ-UHFFFAOYSA-N citronellol Chemical compound OCCC(C)CCC=C(C)C QMVPMAAFGQKVCJ-UHFFFAOYSA-N 0.000 claims 6
- CZCBTSFUTPZVKJ-UHFFFAOYSA-N rose oxide Chemical compound CC1CCOC(C=C(C)C)C1 CZCBTSFUTPZVKJ-UHFFFAOYSA-N 0.000 claims 6
- 208000002193 Pain Diseases 0.000 claims 5
- NEHNMFOYXAPHSD-UHFFFAOYSA-N citronellal Chemical compound O=CCC(C)CCC=C(C)C NEHNMFOYXAPHSD-UHFFFAOYSA-N 0.000 claims 5
- 150000001875 compounds Chemical class 0.000 claims 5
- 150000003505 terpenes Chemical class 0.000 claims 5
- 241000134874 Geraniales Species 0.000 claims 4
- GLZPCOQZEFWAFX-YFHOEESVSA-N Geraniol Natural products CC(C)=CCC\C(C)=C/CO GLZPCOQZEFWAFX-YFHOEESVSA-N 0.000 claims 4
- 239000005792 Geraniol Substances 0.000 claims 4
- 206010028980 Neoplasm Diseases 0.000 claims 4
- GLZPCOQZEFWAFX-JXMROGBWSA-N Nerol Natural products CC(C)=CCC\C(C)=C\CO GLZPCOQZEFWAFX-JXMROGBWSA-N 0.000 claims 4
- ZSBOMYJPSRFZAL-JLHYYAGUSA-N [(2e)-3,7-dimethylocta-2,6-dienyl] butanoate Chemical compound CCCC(=O)OC\C=C(/C)CCC=C(C)C ZSBOMYJPSRFZAL-JLHYYAGUSA-N 0.000 claims 4
- 201000011510 cancer Diseases 0.000 claims 4
- 229940113087 geraniol Drugs 0.000 claims 4
- FQMZVFJYMPNUCT-UHFFFAOYSA-N geraniol formate Natural products CC(C)=CCCC(C)=CCOC=O FQMZVFJYMPNUCT-UHFFFAOYSA-N 0.000 claims 4
- 208000015181 infectious disease Diseases 0.000 claims 4
- 208000004296 neuralgia Diseases 0.000 claims 4
- 208000021722 neuropathic pain Diseases 0.000 claims 4
- 208000011580 syndromic disease Diseases 0.000 claims 4
- NFLGAXVYCFJBMK-RKDXNWHRSA-N (+)-isomenthone Natural products CC(C)[C@H]1CC[C@@H](C)CC1=O NFLGAXVYCFJBMK-RKDXNWHRSA-N 0.000 claims 3
- VVUMWAHNKOLVSN-UHFFFAOYSA-N 2-(4-ethoxyanilino)-n-propylpropanamide Chemical compound CCCNC(=O)C(C)NC1=CC=C(OCC)C=C1 VVUMWAHNKOLVSN-UHFFFAOYSA-N 0.000 claims 3
- IYYUJCKJSSPXQQ-UHFFFAOYSA-N 2-pyridin-4-yl-1,3-thiazolidin-3-ium-4-carboxylate Chemical compound N1C(C(=O)O)CSC1C1=CC=NC=C1 IYYUJCKJSSPXQQ-UHFFFAOYSA-N 0.000 claims 3
- UCFQYMKLDPWFHZ-MKMNVTDBSA-N 3,7-dimethyloct-6-enyl (e)-2-methylbut-2-enoate Chemical compound C\C=C(/C)C(=O)OCCC(C)CCC=C(C)C UCFQYMKLDPWFHZ-MKMNVTDBSA-N 0.000 claims 3
- OGHBUHJLMHQMHS-UHFFFAOYSA-N 3,7-dimethylocta-2,6-dienyl 2-methylbut-2-enoate Chemical compound CC=C(C)C(=O)OCC=C(C)CCC=C(C)C OGHBUHJLMHQMHS-UHFFFAOYSA-N 0.000 claims 3
- NFLGAXVYCFJBMK-UHFFFAOYSA-N Menthone Chemical compound CC(C)C1CCC(C)CC1=O NFLGAXVYCFJBMK-UHFFFAOYSA-N 0.000 claims 3
- WTEVQBCEXWBHNA-YFHOEESVSA-N citral B Natural products CC(C)=CCC\C(C)=C/C=O WTEVQBCEXWBHNA-YFHOEESVSA-N 0.000 claims 3
- 229930003633 citronellal Natural products 0.000 claims 3
- 235000000983 citronellal Nutrition 0.000 claims 3
- 235000000484 citronellol Nutrition 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- NHCQMVNKPJAQJZ-UHFFFAOYSA-N geranyl n-butyrate Natural products CCCCOCC=C(C)CCC=C(C)C NHCQMVNKPJAQJZ-UHFFFAOYSA-N 0.000 claims 3
- 229930007503 menthone Natural products 0.000 claims 3
- 125000000896 monocarboxylic acid group Chemical group 0.000 claims 3
- 229930007790 rose oxide Natural products 0.000 claims 3
- ONYJRUXYOCZIAW-BLWKUPHCSA-N (2e,6e)-octa-2,6-dien-1-ol Chemical compound C\C=C\CC\C=C\CO ONYJRUXYOCZIAW-BLWKUPHCSA-N 0.000 claims 2
- QMVPMAAFGQKVCJ-SNVBAGLBSA-N (R)-(+)-citronellol Natural products OCC[C@H](C)CCC=C(C)C QMVPMAAFGQKVCJ-SNVBAGLBSA-N 0.000 claims 2
- 208000023275 Autoimmune disease Diseases 0.000 claims 2
- 208000017667 Chronic Disease Diseases 0.000 claims 2
- 208000013586 Complex regional pain syndrome type 1 Diseases 0.000 claims 2
- 208000032131 Diabetic Neuropathies Diseases 0.000 claims 2
- 208000001640 Fibromyalgia Diseases 0.000 claims 2
- 208000007514 Herpes zoster Diseases 0.000 claims 2
- 208000004983 Phantom Limb Diseases 0.000 claims 2
- 206010036376 Postherpetic Neuralgia Diseases 0.000 claims 2
- 201000001947 Reflex Sympathetic Dystrophy Diseases 0.000 claims 2
- 239000000443 aerosol Substances 0.000 claims 2
- JGQFVRIQXUFPAH-UHFFFAOYSA-N beta-citronellol Natural products OCCC(C)CCCC(C)=C JGQFVRIQXUFPAH-UHFFFAOYSA-N 0.000 claims 2
- 231100000481 chemical toxicant Toxicity 0.000 claims 2
- 239000006071 cream Substances 0.000 claims 2
- 239000003085 diluting agent Substances 0.000 claims 2
- 208000016097 disease of metabolism Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000000499 gel Substances 0.000 claims 2
- 208000014674 injury Diseases 0.000 claims 2
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 claims 2
- 208000030159 metabolic disease Diseases 0.000 claims 2
- 239000003921 oil Substances 0.000 claims 2
- 230000004768 organ dysfunction Effects 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 239000006187 pill Substances 0.000 claims 2
- 239000007921 spray Substances 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- 239000003440 toxic substance Substances 0.000 claims 2
- 230000008733 trauma Effects 0.000 claims 2
- 206010044652 trigeminal neuralgia Diseases 0.000 claims 2
- 208000019553 vascular disease Diseases 0.000 claims 2
- 239000001490 (3R)-3,7-dimethylocta-1,6-dien-3-ol Substances 0.000 claims 1
- FQMZVFJYMPNUCT-YRNVUSSQSA-N (E)-geranyl formate Chemical compound CC(C)=CCC\C(C)=C\COC=O FQMZVFJYMPNUCT-YRNVUSSQSA-N 0.000 claims 1
- CDOSHBSSFJOMGT-JTQLQIEISA-N (R)-linalool Natural products CC(C)=CCC[C@@](C)(O)C=C CDOSHBSSFJOMGT-JTQLQIEISA-N 0.000 claims 1
- WUOACPNHFRMFPN-SECBINFHSA-N (S)-(-)-alpha-terpineol Chemical compound CC1=CC[C@@H](C(C)(C)O)CC1 WUOACPNHFRMFPN-SECBINFHSA-N 0.000 claims 1
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Natural products CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 claims 1
- BXNJGRQTGXKMAO-IVSSQYLWSA-N C/C(/COC(C=CC)=O)=C(\CCC=C(C)C)/C Chemical compound C/C(/COC(C=CC)=O)=C(\CCC=C(C)C)/C BXNJGRQTGXKMAO-IVSSQYLWSA-N 0.000 claims 1
- ZVFUDSZAIQLCRN-UHFFFAOYSA-N CC(COC(C=CC)=O)C(CCC=C(C)C)C Chemical compound CC(COC(C=CC)=O)C(CCC=C(C)C)C ZVFUDSZAIQLCRN-UHFFFAOYSA-N 0.000 claims 1
- 208000004454 Hyperalgesia Diseases 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 206010053552 allodynia Diseases 0.000 claims 1
- OVKDFILSBMEKLT-UHFFFAOYSA-N alpha-Terpineol Natural products CC(=C)C1(O)CCC(C)=CC1 OVKDFILSBMEKLT-UHFFFAOYSA-N 0.000 claims 1
- 229940088601 alpha-terpineol Drugs 0.000 claims 1
- 150000001408 amides Chemical group 0.000 claims 1
- 150000001412 amines Chemical group 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 230000005284 excitation Effects 0.000 claims 1
- 150000004820 halides Chemical group 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 229930007744 linalool Natural products 0.000 claims 1
- SYSQUGFVNFXIIT-UHFFFAOYSA-N n-[4-(1,3-benzoxazol-2-yl)phenyl]-4-nitrobenzenesulfonamide Chemical class C1=CC([N+](=O)[O-])=CC=C1S(=O)(=O)NC1=CC=C(C=2OC3=CC=CC=C3N=2)C=C1 SYSQUGFVNFXIIT-UHFFFAOYSA-N 0.000 claims 1
- 230000001537 neural effect Effects 0.000 claims 1
- 201000001119 neuropathy Diseases 0.000 claims 1
- 230000007823 neuropathy Effects 0.000 claims 1
- 231100000862 numbness Toxicity 0.000 claims 1
- SHPVOXFREBUEHB-UHFFFAOYSA-N oct-6-en-1-ol Chemical compound CC=CCCCCCO SHPVOXFREBUEHB-UHFFFAOYSA-N 0.000 claims 1
- 208000033808 peripheral neuropathy Diseases 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical group [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000010452 phosphate Chemical group 0.000 claims 1
- 230000005062 synaptic transmission Effects 0.000 claims 1
- 150000003573 thiols Chemical group 0.000 claims 1
- 238000011200 topical administration Methods 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89964207P | 2007-02-06 | 2007-02-06 | |
| US60/899,642 | 2007-02-06 | ||
| PCT/CA2008/000236 WO2008095297A1 (en) | 2007-02-06 | 2008-02-06 | Composition comprising terpene compounds and methods for inhibiting nerve transmission |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016013591A Division JP6144785B2 (ja) | 2007-02-06 | 2016-01-27 | 神経障害性疼痛を治療するための組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010518030A JP2010518030A (ja) | 2010-05-27 |
| JP2010518030A5 true JP2010518030A5 (enExample) | 2011-03-17 |
| JP5933164B2 JP5933164B2 (ja) | 2016-06-08 |
Family
ID=39681217
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009548553A Expired - Fee Related JP5933164B2 (ja) | 2007-02-06 | 2008-02-06 | テルペン化合物を含む組成物及び神経伝達の抑制方法 |
| JP2016013591A Expired - Fee Related JP6144785B2 (ja) | 2007-02-06 | 2016-01-27 | 神経障害性疼痛を治療するための組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016013591A Expired - Fee Related JP6144785B2 (ja) | 2007-02-06 | 2016-01-27 | 神経障害性疼痛を治療するための組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9999601B2 (enExample) |
| EP (1) | EP2142182B1 (enExample) |
| JP (2) | JP5933164B2 (enExample) |
| KR (2) | KR20150046328A (enExample) |
| CN (2) | CN105581999A (enExample) |
| AU (1) | AU2008213772A1 (enExample) |
| CA (1) | CA2676139C (enExample) |
| HK (1) | HK1224231A1 (enExample) |
| WO (1) | WO2008095297A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105581999A (zh) | 2007-02-06 | 2016-05-18 | 安元有限公司 | 用于抑制神经传导的包括萜烯化合物的组合物以及方法 |
| WO2008112641A2 (en) | 2007-03-09 | 2008-09-18 | New York University | Methods and compositions for treating thalamocortical dysrhythmia |
| CA2732784C (en) * | 2008-08-13 | 2018-09-18 | Neuroquest Inc. | Compositions comprising terpene compounds for treating negative sensory phenomena |
| CA2811241A1 (en) * | 2010-09-14 | 2012-03-22 | Neuroquest Inc. | Terpenoid analogues and uses thereof for treating neurological conditions |
| WO2012053003A1 (en) * | 2010-10-18 | 2012-04-26 | Anil Kumar Gupta | A novel herbal oil for controlling blood sugar without risk of hypoglycemea |
| CA2841972A1 (en) * | 2011-07-14 | 2013-01-17 | Neuroquest Inc. | Terpene analogues and uses thereof for treating neurological conditions |
| US9228727B2 (en) | 2012-04-05 | 2016-01-05 | Michael W. May | Lighting assembly |
| WO2013168090A1 (en) | 2012-05-07 | 2013-11-14 | The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Researc Organization (Aro) (Volcanii Center). | Geranium oil and constituents thereof for treatment of neurodegenerative diseases |
| WO2014051113A1 (ja) | 2012-09-28 | 2014-04-03 | 株式会社資生堂 | Ｖｅｇｆｃ産生促進剤 |
| WO2014187946A1 (en) * | 2013-05-24 | 2014-11-27 | Nestec S.A. | Treatment or prevention of autism disorders using menthol, linalool and/or icilin |
| US10493042B2 (en) | 2013-08-01 | 2019-12-03 | University-Industry Cooperation Group Of Kyung Hee University | Method for preventing or treating diabetes mellitus, and method for screening for diabetes mellitus therapeutic agent |
| WO2015016682A1 (ko) | 2013-08-01 | 2015-02-05 | 경희대학교 산학협력단 | 당뇨병 예방 또는 치료용 약학적 조성물, 당뇨병 예방 또는 치료 방법, 및 당뇨병 치료제 스크리닝 방법 |
| KR102250582B1 (ko) | 2018-05-11 | 2021-05-12 | 고려대학교 산학협력단 | 별아교세포 특이적 수동전도도 억제약물의 스크리닝 시스템 및 이의 활용 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1555333A (en) | 1975-05-29 | 1979-11-07 | Bush Boake Allen Ltd | Perfumery compositions comprising hydroxy- or alkoxy-substituted c9 alkanals alkanols and esters |
| NZ190416A (en) | 1978-05-16 | 1981-05-29 | Unilever Ltd | Deodorant product |
| CH673931A5 (enExample) | 1986-05-08 | 1990-04-30 | R & C Products Pty Ltd | |
| DE3779500T2 (de) | 1986-06-10 | 1993-01-21 | Chiesi Farma Spa | Levodopa-methyl-ester enthaltende pharmazeutische zusammensetzungen, ihre herstellung und therapeutische verwendungen. |
| DE3725248A1 (de) | 1987-07-30 | 1989-02-09 | Henkel Kgaa | Antimikrobiell wirksame, aromatisierte zubereitungen |
| US5770738A (en) | 1992-03-05 | 1998-06-23 | Boehringer Ingelheim Kg | Esters of bi- and tricyclic amino alcohols, their preparation and their use in pharmaceutical compositions |
| US5260313A (en) * | 1992-03-12 | 1993-11-09 | National Pain Institute, Inc. | Diagnosis and treatment of various neuralgias |
| US6248307B1 (en) | 1999-04-14 | 2001-06-19 | Standard Homeopathic Company | Compositions and treatment for alleviation of symptoms associated with menopause |
| EP1424071B1 (en) | 2001-08-08 | 2008-08-20 | Shiseido Company Limited | Perfume compositions |
| US20030092636A1 (en) | 2001-11-06 | 2003-05-15 | Silberstein Stephen D. | Treatment and prevention of paresthesia comprising co-therapy with anticonvulsant derivatives and potassium |
| AU2002360517A1 (en) * | 2001-12-07 | 2003-06-23 | Ximed Group Plc | Respiratory infection prevention and treatment with terpene-containing compositions |
| US20030224072A1 (en) * | 2002-06-03 | 2003-12-04 | Frome Bruce Marshall | Topical and oral administration of a composition containing Pelargonium Graveolens for diagnosis and treatment of various neuralgias and other conditions |
| US7943166B2 (en) * | 2003-04-10 | 2011-05-17 | Neurogesx, Inc. | Methods and compositions for administration of TRPV1 agonists |
| US20050025823A1 (en) * | 2003-07-29 | 2005-02-03 | Fong Andy A.T. | Methods of use of herbal compositions |
| US20050112183A1 (en) | 2003-11-25 | 2005-05-26 | Galer Bradley S. | Compositions and methods for treating neuropathic sensory loss |
| US20060004050A1 (en) | 2004-07-02 | 2006-01-05 | Speicher Brian T | Compositions and methods for the prevention or treatment of pain and other nervous system disorders |
| WO2006105481A1 (en) * | 2005-03-30 | 2006-10-05 | Neurogesx, Inc. | Low-concentration capsaicin patch and methods for treating neuropathic pain |
| US20070203080A1 (en) | 2006-02-15 | 2007-08-30 | The Regents Of The University Of California | New Drug Delivery System for Crossing the Blood Brain Barrier |
| WO2008108825A2 (en) | 2006-10-10 | 2008-09-12 | Burnham Institute For Medical Research | Neuroprotective compositions and methods |
| KR20090082507A (ko) * | 2006-11-20 | 2009-07-30 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 통증 및 소양증 치료용 방법, 조성물 및 키트 |
| CN105581999A (zh) * | 2007-02-06 | 2016-05-18 | 安元有限公司 | 用于抑制神经传导的包括萜烯化合物的组合物以及方法 |
| US8236239B2 (en) | 2007-11-16 | 2012-08-07 | Bernstein Eric F | Sterilizing compositions comprising phosphors for converting electromagnetic radiation to UVC radiation and methods for using the same |
| GB2460214A (en) | 2008-03-20 | 2009-11-25 | Hexcel Composites Ltd | Prepregs for use in making laminates of reduced porosity |
| FR2934925B1 (fr) * | 2008-08-06 | 2011-02-25 | Soitec Silicon On Insulator | Procede de fabrication d'une structure comprernant une etape d'implantations d'ions pour stabiliser l'interface de collage. |
| CA2732784C (en) | 2008-08-13 | 2018-09-18 | Neuroquest Inc. | Compositions comprising terpene compounds for treating negative sensory phenomena |
| WO2010057295A1 (en) | 2008-11-18 | 2010-05-27 | Origin Biomed Inc. | Homeopathic composition comprising hypericum perforatum extract and essential oils for the treatment of neuropathic pain |
| CA2811241A1 (en) | 2010-09-14 | 2012-03-22 | Neuroquest Inc. | Terpenoid analogues and uses thereof for treating neurological conditions |
| CA2841972A1 (en) | 2011-07-14 | 2013-01-17 | Neuroquest Inc. | Terpene analogues and uses thereof for treating neurological conditions |
-
2008
- 2008-02-06 CN CN201511021134.2A patent/CN105581999A/zh active Pending
- 2008-02-06 JP JP2009548553A patent/JP5933164B2/ja not_active Expired - Fee Related
- 2008-02-06 CN CN200880006917A patent/CN101677973A/zh active Pending
- 2008-02-06 AU AU2008213772A patent/AU2008213772A1/en not_active Abandoned
- 2008-02-06 EP EP08714559.5A patent/EP2142182B1/en not_active Not-in-force
- 2008-02-06 CA CA2676139A patent/CA2676139C/en active Active
- 2008-02-06 WO PCT/CA2008/000236 patent/WO2008095297A1/en not_active Ceased
- 2008-02-06 KR KR20157008120A patent/KR20150046328A/ko not_active Withdrawn
- 2008-02-06 KR KR1020097018619A patent/KR101580857B1/ko not_active Expired - Fee Related
-
2009
- 2009-08-06 US US12/537,095 patent/US9999601B2/en not_active Expired - Fee Related
-
2016
- 2016-01-27 JP JP2016013591A patent/JP6144785B2/ja not_active Expired - Fee Related
- 2016-11-04 HK HK16112719.7A patent/HK1224231A1/zh unknown
-
2018
- 2018-01-19 US US15/875,060 patent/US20180207110A1/en not_active Abandoned
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