CN105581999A - 用于抑制神经传导的包括萜烯化合物的组合物以及方法 - Google Patents

用于抑制神经传导的包括萜烯化合物的组合物以及方法 Download PDF

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Publication number
CN105581999A
CN105581999A CN201511021134.2A CN201511021134A CN105581999A CN 105581999 A CN105581999 A CN 105581999A CN 201511021134 A CN201511021134 A CN 201511021134A CN 105581999 A CN105581999 A CN 105581999A
Authority
CN
China
Prior art keywords
composition
terpene compound
geraniol
neuropathic pain
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201511021134.2A
Other languages
English (en)
Chinese (zh)
Inventor
亚历山大·麦克莱伦
弗兰克·格林韦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Luis Anna State University Monitoring Committee College Of Agriculture And Mechanical Engineering
Neuroquest Inc
Original Assignee
Luis Anna State University Monitoring Committee College Of Agriculture And Mechanical Engineering
Neuroquest Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Luis Anna State University Monitoring Committee College Of Agriculture And Mechanical Engineering, Neuroquest Inc filed Critical Luis Anna State University Monitoring Committee College Of Agriculture And Mechanical Engineering
Publication of CN105581999A publication Critical patent/CN105581999A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/11—Aldehydes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Neurosurgery (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dispersion Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
CN201511021134.2A 2007-02-06 2008-02-06 用于抑制神经传导的包括萜烯化合物的组合物以及方法 Pending CN105581999A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89964207P 2007-02-06 2007-02-06
US60/899,642 2007-02-06
CN200880006917A CN101677973A (zh) 2007-02-06 2008-02-06 用于抑制神经传导的包括萜烯化合物的组合物以及方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN200880006917A Division CN101677973A (zh) 2007-02-06 2008-02-06 用于抑制神经传导的包括萜烯化合物的组合物以及方法

Publications (1)

Publication Number Publication Date
CN105581999A true CN105581999A (zh) 2016-05-18

Family

ID=39681217

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201511021134.2A Pending CN105581999A (zh) 2007-02-06 2008-02-06 用于抑制神经传导的包括萜烯化合物的组合物以及方法
CN200880006917A Pending CN101677973A (zh) 2007-02-06 2008-02-06 用于抑制神经传导的包括萜烯化合物的组合物以及方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN200880006917A Pending CN101677973A (zh) 2007-02-06 2008-02-06 用于抑制神经传导的包括萜烯化合物的组合物以及方法

Country Status (9)

Country Link
US (2) US9999601B2 (enExample)
EP (1) EP2142182B1 (enExample)
JP (2) JP5933164B2 (enExample)
KR (2) KR20150046328A (enExample)
CN (2) CN105581999A (enExample)
AU (1) AU2008213772A1 (enExample)
CA (1) CA2676139C (enExample)
HK (1) HK1224231A1 (enExample)
WO (1) WO2008095297A1 (enExample)

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CN105581999A (zh) 2007-02-06 2016-05-18 安元有限公司 用于抑制神经传导的包括萜烯化合物的组合物以及方法
WO2008112641A2 (en) 2007-03-09 2008-09-18 New York University Methods and compositions for treating thalamocortical dysrhythmia
CA2732784C (en) * 2008-08-13 2018-09-18 Neuroquest Inc. Compositions comprising terpene compounds for treating negative sensory phenomena
CA2811241A1 (en) * 2010-09-14 2012-03-22 Neuroquest Inc. Terpenoid analogues and uses thereof for treating neurological conditions
WO2012053003A1 (en) * 2010-10-18 2012-04-26 Anil Kumar Gupta A novel herbal oil for controlling blood sugar without risk of hypoglycemea
CA2841972A1 (en) * 2011-07-14 2013-01-17 Neuroquest Inc. Terpene analogues and uses thereof for treating neurological conditions
US9228727B2 (en) 2012-04-05 2016-01-05 Michael W. May Lighting assembly
WO2013168090A1 (en) 2012-05-07 2013-11-14 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Researc Organization (Aro) (Volcanii Center). Geranium oil and constituents thereof for treatment of neurodegenerative diseases
WO2014051113A1 (ja) 2012-09-28 2014-04-03 株式会社資生堂 Ｖｅｇｆｃ産生促進剤
WO2014187946A1 (en) * 2013-05-24 2014-11-27 Nestec S.A. Treatment or prevention of autism disorders using menthol, linalool and/or icilin
US10493042B2 (en) 2013-08-01 2019-12-03 University-Industry Cooperation Group Of Kyung Hee University Method for preventing or treating diabetes mellitus, and method for screening for diabetes mellitus therapeutic agent
WO2015016682A1 (ko) 2013-08-01 2015-02-05 경희대학교 산학협력단 당뇨병 예방 또는 치료용 약학적 조성물, 당뇨병 예방 또는 치료 방법, 및 당뇨병 치료제 스크리닝 방법
KR102250582B1 (ko) 2018-05-11 2021-05-12 고려대학교 산학협력단 별아교세포 특이적 수동전도도 억제약물의 스크리닝 시스템 및 이의 활용

Citations (4)

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US5260313A (en) * 1992-03-12 1993-11-09 National Pain Institute, Inc. Diagnosis and treatment of various neuralgias
WO2003049726A1 (en) * 2001-12-07 2003-06-19 Eden Research Plc Respiratory infection prevention and treatment with terpene-containing compositions
CN1538840A (zh) * 2001-08-08 2004-10-20 ������������ʽ���� 香料组合物
WO2006014788A1 (en) * 2004-07-28 2006-02-09 Medigreen Biotechnology Corp. Methods of use of herbal compositions

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US20030224072A1 (en) * 2002-06-03 2003-12-04 Frome Bruce Marshall Topical and oral administration of a composition containing Pelargonium Graveolens for diagnosis and treatment of various neuralgias and other conditions
US7943166B2 (en) * 2003-04-10 2011-05-17 Neurogesx, Inc. Methods and compositions for administration of TRPV1 agonists
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CA2811241A1 (en) 2010-09-14 2012-03-22 Neuroquest Inc. Terpenoid analogues and uses thereof for treating neurological conditions
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US5260313A (en) * 1992-03-12 1993-11-09 National Pain Institute, Inc. Diagnosis and treatment of various neuralgias
CN1538840A (zh) * 2001-08-08 2004-10-20 ������������ʽ���� 香料组合物
WO2003049726A1 (en) * 2001-12-07 2003-06-19 Eden Research Plc Respiratory infection prevention and treatment with terpene-containing compositions
WO2006014788A1 (en) * 2004-07-28 2006-02-09 Medigreen Biotechnology Corp. Methods of use of herbal compositions

Also Published As

Publication number Publication date
WO2008095297A1 (en) 2008-08-14
HK1224231A1 (zh) 2017-08-18
JP2016121169A (ja) 2016-07-07
AU2008213772A1 (en) 2008-08-14
KR20100014922A (ko) 2010-02-11
US9999601B2 (en) 2018-06-19
JP2010518030A (ja) 2010-05-27
EP2142182A4 (en) 2010-03-03
CA2676139A1 (en) 2008-08-14
US20180207110A1 (en) 2018-07-26
JP6144785B2 (ja) 2017-06-07
EP2142182A1 (en) 2010-01-13
JP5933164B2 (ja) 2016-06-08
CN101677973A (zh) 2010-03-24
EP2142182B1 (en) 2017-09-27
KR20150046328A (ko) 2015-04-29
KR101580857B1 (ko) 2015-12-30
CA2676139C (en) 2016-04-26
US20110257255A1 (en) 2011-10-20

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