JP2010514730A5 - - Google Patents
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- Publication number
- JP2010514730A5 JP2010514730A5 JP2009543465A JP2009543465A JP2010514730A5 JP 2010514730 A5 JP2010514730 A5 JP 2010514730A5 JP 2009543465 A JP2009543465 A JP 2009543465A JP 2009543465 A JP2009543465 A JP 2009543465A JP 2010514730 A5 JP2010514730 A5 JP 2010514730A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- azabicyclo
- ylmethyl
- oct
- phenothiazine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 11
- HOKDBMAJZXIPGC-MRXNPFEDSA-N 10-[[(3r)-1-azabicyclo[2.2.2]octan-3-yl]methyl]phenothiazine Chemical compound C12=CC=CC=C2SC2=CC=CC=C2N1C[C@@H]1C(CC2)CCN2C1 HOKDBMAJZXIPGC-MRXNPFEDSA-N 0.000 claims 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 5
- 206010021639 Incontinence Diseases 0.000 claims 4
- 239000013543 active substance Substances 0.000 claims 2
- 239000002552 dosage form Substances 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 230000000699 topical effect Effects 0.000 claims 2
- 208000035143 Bacterial infection Diseases 0.000 claims 1
- 208000008967 Enuresis Diseases 0.000 claims 1
- 206010017533 Fungal infection Diseases 0.000 claims 1
- 206010020853 Hypertonic bladder Diseases 0.000 claims 1
- 102000014415 Muscarinic acetylcholine receptor Human genes 0.000 claims 1
- 108050003473 Muscarinic acetylcholine receptor Proteins 0.000 claims 1
- 208000031888 Mycoses Diseases 0.000 claims 1
- 208000000693 Neurogenic Urinary Bladder Diseases 0.000 claims 1
- 206010029279 Neurogenic bladder Diseases 0.000 claims 1
- 206010037211 Psychomotor hyperactivity Diseases 0.000 claims 1
- 208000036071 Rhinorrhea Diseases 0.000 claims 1
- 206010039101 Rhinorrhoea Diseases 0.000 claims 1
- 206010066218 Stress Urinary Incontinence Diseases 0.000 claims 1
- 206010046543 Urinary incontinence Diseases 0.000 claims 1
- 230000002159 abnormal effect Effects 0.000 claims 1
- 230000003872 anastomosis Effects 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 208000022362 bacterial infectious disease Diseases 0.000 claims 1
- 230000008602 contraction Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 230000004064 dysfunction Effects 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 230000027939 micturition Effects 0.000 claims 1
- 210000004877 mucosa Anatomy 0.000 claims 1
- 239000006186 oral dosage form Substances 0.000 claims 1
- 230000001575 pathological effect Effects 0.000 claims 1
- CBHCDHNUZWWAPP-UHFFFAOYSA-N pecazine Chemical compound C1N(C)CCCC1CN1C2=CC=CC=C2SC2=CC=CC=C21 CBHCDHNUZWWAPP-UHFFFAOYSA-N 0.000 claims 1
- 229950007538 pecazine Drugs 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 210000005070 sphincter Anatomy 0.000 claims 1
- 239000000829 suppository Substances 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 230000008733 trauma Effects 0.000 claims 1
- 210000003708 urethra Anatomy 0.000 claims 1
- 230000002485 urinary effect Effects 0.000 claims 1
- 229940044953 vaginal ring Drugs 0.000 claims 1
- 239000006213 vaginal ring Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0656002 | 2006-12-28 | ||
| FR0656002A FR2910814B1 (fr) | 2006-12-28 | 2006-12-28 | Utilisation du 10-°(r3)-1-azabicyclo°2.2.2!oct-3-ylmethyl!-10h- phenothiazine pour la preparation d'un medicament exercant une inhibition selective des recepteurs muscariniques m1,2,3 |
| PCT/EP2007/064553 WO2008080924A1 (fr) | 2006-12-28 | 2007-12-26 | Utilisation du 10-[(3r)-1-azabicyclo[2.2.2]oct-3-ylméthyl]-10h-phénothiazine pour la préparation d'un médicament exerçant une inhibition sélective des récepteurs muscariniques m1, m2 et m3 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010514730A JP2010514730A (ja) | 2010-05-06 |
| JP2010514730A5 true JP2010514730A5 (enExample) | 2011-01-13 |
| JP5564263B2 JP5564263B2 (ja) | 2014-07-30 |
Family
ID=37951872
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009543465A Expired - Fee Related JP5564263B2 (ja) | 2006-12-28 | 2007-12-26 | ムスカリンｍ１、ｍ２およびｍ３受容体の選択的阻害を有する薬剤の製造のための１０−［（３ｒ）−１−アザビシクロ［２．２．２］オクト−３−イルメチル］−１０ｈ−フェノチアジンの使用 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8143245B2 (enExample) |
| EP (1) | EP2124956A1 (enExample) |
| JP (1) | JP5564263B2 (enExample) |
| KR (1) | KR101465277B1 (enExample) |
| CN (1) | CN101573120B (enExample) |
| AR (1) | AR064714A1 (enExample) |
| AU (1) | AU2007341274B2 (enExample) |
| BR (1) | BRPI0720591A2 (enExample) |
| CA (1) | CA2674162A1 (enExample) |
| FR (2) | FR2910814B1 (enExample) |
| IL (1) | IL199557A (enExample) |
| MA (1) | MA31026B1 (enExample) |
| MX (1) | MX2009006950A (enExample) |
| NO (1) | NO20092654L (enExample) |
| NZ (1) | NZ577915A (enExample) |
| RU (1) | RU2449794C2 (enExample) |
| TN (1) | TN2009000257A1 (enExample) |
| TW (1) | TWI423806B (enExample) |
| UA (1) | UA98131C2 (enExample) |
| WO (1) | WO2008080924A1 (enExample) |
| ZA (1) | ZA200904304B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015133989A (ja) * | 2015-04-28 | 2015-07-27 | 重泉 達志 | 健康食品 |
| KR101969263B1 (ko) | 2018-07-16 | 2019-04-15 | 이상호 | 산소 챔버용 산소 공급 장치 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1173445B (it) * | 1984-03-16 | 1987-06-24 | Guidotti & C Spa Labor | Agenti ad attivita' antibroncospastica e composizioni farmaceutiche che li contengono |
| IT1251161B (it) * | 1991-08-07 | 1995-05-04 | Derivati ammonio quaternari di (-) e (+)-3-(10 h-fenotiazin-10-ilmetil)-l-azabiciclo (2.2.2.)ottano e composizioni farmaceutiche che li contengono | |
| AU6686700A (en) | 1999-08-23 | 2001-03-19 | H. Lundbeck A/S | Treatment of urinary incontinence |
| AU2002366800B2 (en) * | 2001-12-20 | 2006-08-03 | Femmepharma Holding Company, Inc. | Vaginal delivery of drugs |
-
2006
- 2006-12-28 FR FR0656002A patent/FR2910814B1/fr not_active Expired - Fee Related
-
2007
- 2007-12-13 TW TW096147644A patent/TWI423806B/zh not_active IP Right Cessation
- 2007-12-26 NZ NZ577915A patent/NZ577915A/en not_active IP Right Cessation
- 2007-12-26 US US12/521,067 patent/US8143245B2/en not_active Expired - Fee Related
- 2007-12-26 RU RU2009128326/15A patent/RU2449794C2/ru not_active IP Right Cessation
- 2007-12-26 JP JP2009543465A patent/JP5564263B2/ja not_active Expired - Fee Related
- 2007-12-26 KR KR1020097013047A patent/KR101465277B1/ko not_active Expired - Fee Related
- 2007-12-26 WO PCT/EP2007/064553 patent/WO2008080924A1/fr not_active Ceased
- 2007-12-26 BR BRPI0720591-0A patent/BRPI0720591A2/pt not_active IP Right Cessation
- 2007-12-26 MX MX2009006950A patent/MX2009006950A/es active IP Right Grant
- 2007-12-26 AU AU2007341274A patent/AU2007341274B2/en not_active Ceased
- 2007-12-26 CN CN2007800467680A patent/CN101573120B/zh not_active Expired - Fee Related
- 2007-12-26 EP EP07858150A patent/EP2124956A1/fr not_active Withdrawn
- 2007-12-26 CA CA002674162A patent/CA2674162A1/fr not_active Abandoned
- 2007-12-26 UA UAA200907928A patent/UA98131C2/ru unknown
- 2007-12-28 AR ARP070105989A patent/AR064714A1/es unknown
-
2009
- 2009-01-01 ZA ZA200904304A patent/ZA200904304B/xx unknown
- 2009-06-23 TN TNP2009000257A patent/TN2009000257A1/fr unknown
- 2009-06-25 IL IL199557A patent/IL199557A/en not_active IP Right Cessation
- 2009-06-26 MA MA32046A patent/MA31026B1/fr unknown
- 2009-07-13 NO NO20092654A patent/NO20092654L/no not_active Application Discontinuation
-
2011
- 2011-03-17 FR FR1152199A patent/FR2953721A1/fr active Pending
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