JP2010509315A5 - - Google Patents

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Publication number
JP2010509315A5
JP2010509315A5 JP2009535878A JP2009535878A JP2010509315A5 JP 2010509315 A5 JP2010509315 A5 JP 2010509315A5 JP 2009535878 A JP2009535878 A JP 2009535878A JP 2009535878 A JP2009535878 A JP 2009535878A JP 2010509315 A5 JP2010509315 A5 JP 2010509315A5
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JP
Japan
Prior art keywords
substituted
targeting agent
antibody
compound according
group
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JP2009535878A
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English (en)
Japanese (ja)
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JP4897050B2 (ja
JP2010509315A (ja
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Priority claimed from PCT/IE2007/000110 external-priority patent/WO2008056346A2/en
Publication of JP2010509315A publication Critical patent/JP2010509315A/ja
Publication of JP2010509315A5 publication Critical patent/JP2010509315A5/ja
Application granted granted Critical
Publication of JP4897050B2 publication Critical patent/JP4897050B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2009535878A 2006-11-10 2007-11-12 抗血管形成化合物 Expired - Fee Related JP4897050B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US86536006P 2006-11-10 2006-11-10
US60/865,360 2006-11-10
US93983007P 2007-05-23 2007-05-23
US60/939,830 2007-05-23
US94532907P 2007-06-20 2007-06-20
US60/945,329 2007-06-20
PCT/IE2007/000110 WO2008056346A2 (en) 2006-11-10 2007-11-12 Anti-angiogenic compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011283619A Division JP2012121886A (ja) 2006-11-10 2011-12-26 抗血管形成化合物

Publications (3)

Publication Number Publication Date
JP2010509315A JP2010509315A (ja) 2010-03-25
JP2010509315A5 true JP2010509315A5 (enExample) 2010-12-16
JP4897050B2 JP4897050B2 (ja) 2012-03-14

Family

ID=39364902

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009535878A Expired - Fee Related JP4897050B2 (ja) 2006-11-10 2007-11-12 抗血管形成化合物
JP2011283619A Ceased JP2012121886A (ja) 2006-11-10 2011-12-26 抗血管形成化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011283619A Ceased JP2012121886A (ja) 2006-11-10 2011-12-26 抗血管形成化合物

Country Status (18)

Country Link
US (3) US8288349B2 (enExample)
EP (2) EP2089425B1 (enExample)
JP (2) JP4897050B2 (enExample)
KR (2) KR101309948B1 (enExample)
CN (1) CN101611053B (enExample)
AT (1) ATE520712T1 (enExample)
AU (1) AU2007318912B2 (enExample)
BR (1) BRPI0718591A2 (enExample)
CA (1) CA2669207A1 (enExample)
DK (1) DK2089425T3 (enExample)
IL (1) IL198581A (enExample)
MX (1) MX2009005045A (enExample)
MY (1) MY146985A (enExample)
NO (1) NO20092203L (enExample)
NZ (1) NZ576751A (enExample)
PL (1) PL2089425T3 (enExample)
PT (1) PT2089425E (enExample)
WO (1) WO2008056346A2 (enExample)

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BRPI0718591A2 (pt) * 2006-11-10 2013-12-03 Covx Technologies Ireland Ltd Compostos antiangiogênicos.
US20090098130A1 (en) * 2007-01-05 2009-04-16 Bradshaw Curt W Glucagon-like protein-1 receptor (glp-1r) agonist compounds
US8293714B2 (en) 2008-05-05 2012-10-23 Covx Technology Ireland, Ltd. Anti-angiogenic compounds
WO2010036930A1 (en) * 2008-09-26 2010-04-01 Javad Parvizi Methods and kits for detecting joint infection
SG186451A1 (en) * 2010-07-12 2013-01-30 Covx Technologies Ireland Ltd Multifunctional antibody conjugates
SG190082A1 (en) 2010-11-05 2013-06-28 Covx Technologies Ireland Ltd Anti-diabetic compounds
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US20130323234A1 (en) * 2012-01-09 2013-12-05 Covx Technologies Ireland Limited Mutant antibodies and conjugation thereof
WO2013148877A1 (en) 2012-03-28 2013-10-03 Amgen Inc. Dr5 receptor agonist combinations
DK3007717T3 (da) 2013-06-12 2019-01-02 Pharis Biotec Gmbh Peptider med antagonistiske aktiviteter mod naturlig cxcr4
WO2015014376A1 (en) * 2013-07-31 2015-02-05 Biontech Ag Diagnosis and therapy of cancer involving cancer stem cells
PT3057585T (pt) * 2013-10-15 2020-10-21 Seagen Inc Fármaco-ligadores peguilados para farmacocinética melhorada de conjugados de fármaco-ligando
WO2016209972A1 (en) 2015-06-26 2016-12-29 Amgen Inc. Biomarker of survival in the treatment of renal cell carcinoma with a vegfr inhibitor and an ang2 inhibitor
US11793880B2 (en) 2015-12-04 2023-10-24 Seagen Inc. Conjugates of quaternized tubulysin compounds
US11229708B2 (en) 2015-12-04 2022-01-25 Seagen Inc. Conjugates of quaternized tubulysin compounds
EP3433278A4 (en) 2016-03-25 2019-11-06 Seattle Genetics, Inc. METHOD FOR THE PRODUCTION OF PEGYLATED ACTIVE LINKERS AND INTERMEDIATE PRODUCTS THEREOF
SG10201912034UA (en) 2017-02-08 2020-02-27 Bristol Myers Squibb Co Modified relaxin polypeptides comprising a pharmacokinetic enhancer and uses thereof
JP7527787B2 (ja) 2017-03-24 2024-08-05 シージェン インコーポレイテッド グルクロニド薬物－リンカーの調製のためのプロセスおよびその中間体
CA3061467A1 (en) 2017-04-28 2019-10-24 Ajinomoto Co., Inc. Compound having affinity substance to soluble protein, cleavable portionand reactive group, or salt thereof

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