AU2007318912B2 - Anti-angiogenic compounds - Google Patents
Anti-angiogenic compounds Download PDFInfo
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- AU2007318912B2 AU2007318912B2 AU2007318912A AU2007318912A AU2007318912B2 AU 2007318912 B2 AU2007318912 B2 AU 2007318912B2 AU 2007318912 A AU2007318912 A AU 2007318912A AU 2007318912 A AU2007318912 A AU 2007318912A AU 2007318912 B2 AU2007318912 B2 AU 2007318912B2
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/515—Angiogenesic factors; Angiogenin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| AU2011202645A AU2011202645B2 (en) | 2006-11-10 | 2011-06-03 | Anti-angiogenic compounds |
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| US94532907P | 2007-06-20 | 2007-06-20 | |
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| PCT/IE2007/000110 WO2008056346A2 (en) | 2006-11-10 | 2007-11-12 | Anti-angiogenic compounds |
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| AU2011202645A Division AU2011202645B2 (en) | 2006-11-10 | 2011-06-03 | Anti-angiogenic compounds |
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| JP (2) | JP4897050B2 (enExample) |
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| PT (1) | PT2089425E (enExample) |
| WO (1) | WO2008056346A2 (enExample) |
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| KR20120043028A (ko) * | 2006-11-10 | 2012-05-03 | 씨오브이엑스 테크놀로지스 아일랜드 리미티드 | 혈관 신생 억제 화합물 |
| US20090098130A1 (en) * | 2007-01-05 | 2009-04-16 | Bradshaw Curt W | Glucagon-like protein-1 receptor (glp-1r) agonist compounds |
| US8293714B2 (en) * | 2008-05-05 | 2012-10-23 | Covx Technology Ireland, Ltd. | Anti-angiogenic compounds |
| WO2010036930A1 (en) * | 2008-09-26 | 2010-04-01 | Javad Parvizi | Methods and kits for detecting joint infection |
| EP2593142B8 (en) * | 2010-07-12 | 2018-12-26 | Pfizer Healthcare Ireland | Multifunctional antibody conjugates |
| RU2013118441A (ru) | 2010-11-05 | 2014-12-10 | КовЭкс Текнолоджиз Айэлэнд Лимитед | Антидиабетические соединения |
| JP6069312B2 (ja) | 2011-06-29 | 2017-02-01 | アムジェン インコーポレイテッド | 腎細胞癌の治療における生存の予測バイオマーカー |
| CA2860109C (en) * | 2011-12-20 | 2016-08-09 | Javier Magano | Improved processes for preparing peptide conjugates and linkers |
| TW201341401A (zh) * | 2012-01-09 | 2013-10-16 | Covx Technologies Ireland Ltd | 突變抗體及其共軛 |
| JP6219923B2 (ja) | 2012-03-28 | 2017-10-25 | アムジェン インコーポレイテッド | Ｄｒ５受容体アゴニストの組み合わせ |
| EP3007717B1 (en) | 2013-06-12 | 2018-08-29 | Pharis Biotec GmbH | Peptides with antagonistic activities against natural cxcr4 |
| WO2015014376A1 (en) * | 2013-07-31 | 2015-02-05 | Biontech Ag | Diagnosis and therapy of cancer involving cancer stem cells |
| BR112016007622A2 (pt) | 2013-10-15 | 2018-01-23 | Seattle Genetics, Inc. | composto, composição farmacêutica, conjugado de ligante-droga, e, método para tratar câncer |
| WO2016209972A1 (en) | 2015-06-26 | 2016-12-29 | Amgen Inc. | Biomarker of survival in the treatment of renal cell carcinoma with a vegfr inhibitor and an ang2 inhibitor |
| SG11201804268RA (en) | 2015-12-04 | 2018-06-28 | Seattle Genetics Inc | Conjugates of quaternized tubulysin compounds |
| US11793880B2 (en) | 2015-12-04 | 2023-10-24 | Seagen Inc. | Conjugates of quaternized tubulysin compounds |
| BR112018069273A2 (pt) | 2016-03-25 | 2019-01-22 | Seattle Genetics Inc | métodos para preparação de um composto e para tratamento de um indivíduo com uma malignidade hematológica, composto, composição, e, intermediário ligante de fármaco ou composto ligante de fármaco |
| MX2019008449A (es) | 2017-02-08 | 2019-09-09 | Bristol Myers Squibb Co | Polipetidos de relaxina modificada que comprenden un mejorador farmacocinetico y sus usos. |
| US11730822B2 (en) | 2017-03-24 | 2023-08-22 | Seagen Inc. | Process for the preparation of glucuronide drug-linkers and intermediates thereof |
| EP3617235A4 (en) | 2017-04-28 | 2020-12-16 | Ajinomoto Co., Inc. | COMPOUND CONTAINING A SUBSTANCE HAVING AFFINITY FOR A SOLUBLE PROTEIN, CLIVABLE FRACTION, AND REACTIVE GROUP, OR SALT OF THE SAME |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004092215A2 (en) * | 2003-04-09 | 2004-10-28 | Amgen Inc. | Methods of treatment of inflammatory diseases using specific binding agents of human angiopoietin-2 |
| WO2006010057A2 (en) * | 2004-07-08 | 2006-01-26 | Amgen Inc. | Therapeutic peptides |
| WO2006036834A2 (en) * | 2004-09-24 | 2006-04-06 | Amgen Inc. | MODIFIED Fc MOLECULES |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US3719667A (en) | 1970-08-24 | 1973-03-06 | Lilly Co Eli | Epimerization of 6-acylamido and 6-imido penicillin sulfoxide esters |
| US3840556A (en) | 1971-05-28 | 1974-10-08 | Lilly Co Eli | Penicillin conversion by halogen electrophiles and anti-bacterials derived thereby |
| US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
| US5216132A (en) | 1990-01-12 | 1993-06-01 | Protein Design Labs, Inc. | Soluble t-cell antigen receptor chimeric antigens |
| DE69126871T2 (de) | 1990-04-06 | 1998-03-12 | Jolla Cancer Res Found | Verfahren und verbindung zur behandlung von thrombose |
| US5229275A (en) | 1990-04-26 | 1993-07-20 | Akzo N.V. | In-vitro method for producing antigen-specific human monoclonal antibodies |
| US5565332A (en) | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| US6080840A (en) | 1992-01-17 | 2000-06-27 | Slanetz; Alfred E. | Soluble T cell receptors |
| US5573905A (en) | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
| US5981478A (en) | 1993-11-24 | 1999-11-09 | La Jolla Cancer Research Foundation | Integrin-binding peptides |
| US5733757A (en) | 1995-12-15 | 1998-03-31 | The Scripps Research Institute | Aldolase catalytic antibody |
| US5739277A (en) | 1995-04-14 | 1998-04-14 | Genentech Inc. | Altered polypeptides with increased half-life |
| DE19544393A1 (de) | 1995-11-15 | 1997-05-22 | Hoechst Schering Agrevo Gmbh | Synergistische herbizide Mischungen |
| GB9722131D0 (en) | 1997-10-20 | 1997-12-17 | Medical Res Council | Method |
| US6326176B1 (en) | 1997-12-18 | 2001-12-04 | The Scripps Research Institute | Aldol condensations by catalytic antibodies |
| AU1190101A (en) | 1999-09-27 | 2001-04-30 | Regents Of The University Of California, The | Engineering antibodies that bind irreversibly |
| US6294374B1 (en) | 1999-10-08 | 2001-09-25 | The Scripps Research Institute | Use of catalytic antibodies for synthesizing epothilone |
| DE60237282D1 (de) | 2001-06-28 | 2010-09-23 | Domantis Ltd | Doppelspezifischer ligand und dessen verwendung |
| US20030045477A1 (en) | 2001-07-26 | 2003-03-06 | Fortuna Haviv | Peptides having antiangiogenic activity |
| US7138370B2 (en) | 2001-10-11 | 2006-11-21 | Amgen Inc. | Specific binding agents of human angiopoietin-2 |
| KR20040058229A (ko) * | 2001-10-22 | 2004-07-03 | 더 스크립스 리서치 인스티튜트 | 항체 표적화 화합물 |
| US6737524B2 (en) * | 2002-03-25 | 2004-05-18 | Paul K. Smith | Activated polyethylene glycol compounds |
| DK1517921T3 (da) | 2002-06-28 | 2006-10-09 | Domantis Ltd | Immunglobulin-enkeltvariable antigen-bindende domæner og dobbeltspecifikke konstruktioner deraf |
| CA2511910A1 (en) | 2002-12-27 | 2004-07-15 | Domantis Limited | Dual specific single domain antibodies specific for a ligand and for the receptor of the ligand |
| KR20120043028A (ko) * | 2006-11-10 | 2012-05-03 | 씨오브이엑스 테크놀로지스 아일랜드 리미티드 | 혈관 신생 억제 화합물 |
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2007
- 2007-11-12 KR KR1020127005049A patent/KR20120043028A/ko not_active Ceased
- 2007-11-12 PL PL07827123T patent/PL2089425T3/pl unknown
- 2007-11-12 EP EP07827123A patent/EP2089425B1/en not_active Not-in-force
- 2007-11-12 EP EP20110170480 patent/EP2368908A3/en not_active Withdrawn
- 2007-11-12 NZ NZ576751A patent/NZ576751A/en not_active IP Right Cessation
- 2007-11-12 AU AU2007318912A patent/AU2007318912B2/en not_active Ceased
- 2007-11-12 MX MX2009005045A patent/MX2009005045A/es active IP Right Grant
- 2007-11-12 CN CN200780049649.0A patent/CN101611053B/zh not_active Expired - Fee Related
- 2007-11-12 PT PT07827123T patent/PT2089425E/pt unknown
- 2007-11-12 CA CA002669207A patent/CA2669207A1/en not_active Abandoned
- 2007-11-12 US US11/938,766 patent/US8288349B2/en not_active Expired - Fee Related
- 2007-11-12 KR KR1020097011924A patent/KR101309948B1/ko not_active Expired - Fee Related
- 2007-11-12 AT AT07827123T patent/ATE520712T1/de active
- 2007-11-12 WO PCT/IE2007/000110 patent/WO2008056346A2/en not_active Ceased
- 2007-11-12 MY MYPI20091889A patent/MY146985A/en unknown
- 2007-11-12 BR BRPI0718591-0A patent/BRPI0718591A2/pt not_active IP Right Cessation
- 2007-11-12 JP JP2009535878A patent/JP4897050B2/ja not_active Expired - Fee Related
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2009
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2011
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2012
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2014
- 2014-10-31 US US14/530,444 patent/US20150057431A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004092215A2 (en) * | 2003-04-09 | 2004-10-28 | Amgen Inc. | Methods of treatment of inflammatory diseases using specific binding agents of human angiopoietin-2 |
| WO2006010057A2 (en) * | 2004-07-08 | 2006-01-26 | Amgen Inc. | Therapeutic peptides |
| WO2006036834A2 (en) * | 2004-09-24 | 2006-04-06 | Amgen Inc. | MODIFIED Fc MOLECULES |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008056346A2 (en) | 2008-05-15 |
| KR20120043028A (ko) | 2012-05-03 |
| KR20090090331A (ko) | 2009-08-25 |
| US8912148B2 (en) | 2014-12-16 |
| AU2007318912A1 (en) | 2008-05-15 |
| WO2008056346A3 (en) | 2008-10-23 |
| CA2669207A1 (en) | 2008-05-15 |
| NZ576751A (en) | 2011-10-28 |
| EP2089425A2 (en) | 2009-08-19 |
| KR101309948B1 (ko) | 2013-09-23 |
| BRPI0718591A2 (pt) | 2013-12-03 |
| IL198581A (en) | 2015-10-29 |
| EP2089425B1 (en) | 2011-08-17 |
| PT2089425E (pt) | 2011-10-17 |
| DK2089425T3 (da) | 2011-10-10 |
| WO2008056346B1 (en) | 2008-12-04 |
| CN101611053A (zh) | 2009-12-23 |
| US20080166364A1 (en) | 2008-07-10 |
| JP2010509315A (ja) | 2010-03-25 |
| US8288349B2 (en) | 2012-10-16 |
| NO20092203L (no) | 2009-08-10 |
| MX2009005045A (es) | 2009-11-10 |
| EP2368908A3 (en) | 2011-10-12 |
| JP4897050B2 (ja) | 2012-03-14 |
| JP2012121886A (ja) | 2012-06-28 |
| US20120301431A1 (en) | 2012-11-29 |
| MY146985A (en) | 2012-10-15 |
| IL198581A0 (en) | 2011-08-01 |
| PL2089425T3 (pl) | 2012-02-29 |
| EP2368908A2 (en) | 2011-09-28 |
| CN101611053B (zh) | 2015-06-03 |
| US20150057431A1 (en) | 2015-02-26 |
| ATE520712T1 (de) | 2011-09-15 |
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| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |