JP2010507590A5 - - Google Patents
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- Publication number
- JP2010507590A5 JP2010507590A5 JP2009533586A JP2009533586A JP2010507590A5 JP 2010507590 A5 JP2010507590 A5 JP 2010507590A5 JP 2009533586 A JP2009533586 A JP 2009533586A JP 2009533586 A JP2009533586 A JP 2009533586A JP 2010507590 A5 JP2010507590 A5 JP 2010507590A5
- Authority
- JP
- Japan
- Prior art keywords
- ocf
- cyclopropyl
- formula
- acceptable salt
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C*1C=CC(C(CC(C2=O)NC(*)(*)C3=CN=C*(*)C=C3)N2c2ccc(*)cc2)=CC=C1 Chemical compound C*1C=CC(C(CC(C2=O)NC(*)(*)C3=CN=C*(*)C=C3)N2c2ccc(*)cc2)=CC=C1 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86254006P | 2006-10-23 | 2006-10-23 | |
| US60/862,540 | 2006-10-23 | ||
| PCT/US2007/082042 WO2008070306A2 (en) | 2006-10-23 | 2007-10-22 | 1,5-diphenyl-3-benzylamin0-1,5-dihydr0pyrr0lidin-2-0ne as cb1 receptor modulators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010507590A JP2010507590A (ja) | 2010-03-11 |
| JP2010507590A5 true JP2010507590A5 (OSRAM) | 2010-11-25 |
| JP5331002B2 JP5331002B2 (ja) | 2013-10-30 |
Family
ID=39386481
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009533585A Expired - Fee Related JP5331001B2 (ja) | 2006-10-23 | 2007-10-22 | Ｃｂ１受容体モジュレーターとしての１，５−ジフェニル−３−ピリジニルアミノ−１，５−ジヒドロピロリジン−２−オン |
| JP2009533586A Expired - Fee Related JP5331002B2 (ja) | 2006-10-23 | 2007-10-22 | Ｃｂ１受容体モジュレーターとしての１，５−ジフェニル−３−ベンジルアミノ−１，５−ジヒドロピロリジン−２−オン |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009533585A Expired - Fee Related JP5331001B2 (ja) | 2006-10-23 | 2007-10-22 | Ｃｂ１受容体モジュレーターとしての１，５−ジフェニル−３−ピリジニルアミノ−１，５−ジヒドロピロリジン−２−オン |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US7998985B2 (OSRAM) |
| EP (2) | EP2094684B1 (OSRAM) |
| JP (2) | JP5331001B2 (OSRAM) |
| KR (2) | KR101088229B1 (OSRAM) |
| CN (2) | CN101528732B (OSRAM) |
| AR (1) | AR063497A1 (OSRAM) |
| AT (1) | ATE492543T1 (OSRAM) |
| AU (1) | AU2007329808B2 (OSRAM) |
| BR (1) | BRPI0717347A2 (OSRAM) |
| CA (2) | CA2667210C (OSRAM) |
| CL (1) | CL2007003002A1 (OSRAM) |
| CY (1) | CY1111140T1 (OSRAM) |
| DE (1) | DE602007011495D1 (OSRAM) |
| DK (2) | DK2099784T3 (OSRAM) |
| EA (2) | EA015745B1 (OSRAM) |
| ES (2) | ES2398388T3 (OSRAM) |
| MX (2) | MX2009004053A (OSRAM) |
| PE (1) | PE20080926A1 (OSRAM) |
| PL (2) | PL2099784T3 (OSRAM) |
| PT (2) | PT2099784E (OSRAM) |
| SI (2) | SI2094684T1 (OSRAM) |
| TW (1) | TW200825067A (OSRAM) |
| WO (2) | WO2008070305A2 (OSRAM) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR063497A1 (es) * | 2006-10-23 | 2009-01-28 | Lilly Co Eli | Compuesto de pirrodinil -2-ona, intermediario para la sintesis del mismo, composicion farmaceutica que lo comprende y su uso para preparar un medicamento |
| EP2280961B1 (en) * | 2008-04-22 | 2012-07-25 | Eli Lilly And Company | 1,5-diphenyl-pyrrolidin-2-one compounds as cb-1 ligands |
| BRPI0910537A2 (pt) * | 2008-04-22 | 2015-09-29 | Lilly Co Eli | composto de 1,5-difenil-pirrolidin-2-ona como ligantes de cb-1 |
| WO2010057000A2 (en) * | 2008-11-13 | 2010-05-20 | The Trustees Of Columbia University In The City Of New York | Neuraminidase inhibitors and uses thereof |
| EA029400B1 (ru) * | 2010-07-15 | 2018-03-30 | Олег Ильич ЭПШТЕЙН | Фармацевтическая композиция для лечения ожирения и сопутствующих метаболических расстройств и способ лечения |
| US10154988B2 (en) | 2012-11-14 | 2018-12-18 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| WO2022132803A1 (en) * | 2020-12-14 | 2022-06-23 | The Board Of Trustees Of The Leland Stanford Junior University | Cb2 receptor agonists |
| WO2023205180A1 (en) | 2022-04-19 | 2023-10-26 | Nurix Therapeutics, Inc. | Biomarkers for cbl, and compositions and methods for their use |
| US20230414598A1 (en) | 2022-06-22 | 2023-12-28 | Nurix Therapeutics, Inc. | Combination therapies with cbl-b inhibitor compounds and antiemetic agents |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200533657A (en) | 2004-02-17 | 2005-10-16 | Esteve Labor Dr | Substituted pyrazoline compounds, their preparation and use as medicaments |
| PT1725536E (pt) | 2004-02-19 | 2009-01-22 | Solvay Pharm Bv | Derivados de imidazolina apresentando actividade antagonista cb1 |
| US20060035245A1 (en) * | 2004-04-20 | 2006-02-16 | Ason Brandon L | Modulators of enzymatic nucleic acid elements mobilization |
| WO2007020502A2 (en) * | 2005-08-16 | 2007-02-22 | Pharmacia & Upjohn Company Llc | Cannabinoid receptor ligands and uses thereof |
| AR063497A1 (es) * | 2006-10-23 | 2009-01-28 | Lilly Co Eli | Compuesto de pirrodinil -2-ona, intermediario para la sintesis del mismo, composicion farmaceutica que lo comprende y su uso para preparar un medicamento |
-
2007
- 2007-10-18 AR ARP070104628A patent/AR063497A1/es unknown
- 2007-10-18 CL CL200703002A patent/CL2007003002A1/es unknown
- 2007-10-18 PE PE2007001418A patent/PE20080926A1/es not_active Application Discontinuation
- 2007-10-18 TW TW096139051A patent/TW200825067A/zh unknown
- 2007-10-22 KR KR1020097008216A patent/KR101088229B1/ko not_active Expired - Fee Related
- 2007-10-22 CN CN2007800394497A patent/CN101528732B/zh not_active Expired - Fee Related
- 2007-10-22 KR KR1020097008214A patent/KR101088236B1/ko not_active Expired - Fee Related
- 2007-10-22 EP EP07871197A patent/EP2094684B1/en not_active Not-in-force
- 2007-10-22 US US12/444,692 patent/US7998985B2/en not_active Expired - Fee Related
- 2007-10-22 SI SI200730538T patent/SI2094684T1/sl unknown
- 2007-10-22 WO PCT/US2007/082041 patent/WO2008070305A2/en not_active Ceased
- 2007-10-22 AT AT07871197T patent/ATE492543T1/de active
- 2007-10-22 ES ES07871196T patent/ES2398388T3/es active Active
- 2007-10-22 PL PL07871196T patent/PL2099784T3/pl unknown
- 2007-10-22 DE DE602007011495T patent/DE602007011495D1/de active Active
- 2007-10-22 EA EA200970404A patent/EA015745B1/ru not_active IP Right Cessation
- 2007-10-22 MX MX2009004053A patent/MX2009004053A/es active IP Right Grant
- 2007-10-22 ES ES07871197T patent/ES2356025T3/es active Active
- 2007-10-22 DK DK07871196.7T patent/DK2099784T3/da active
- 2007-10-22 PT PT78711967T patent/PT2099784E/pt unknown
- 2007-10-22 CN CN2007800394514A patent/CN101528733B/zh not_active Expired - Fee Related
- 2007-10-22 CA CA2667210A patent/CA2667210C/en not_active Expired - Fee Related
- 2007-10-22 DK DK07871197.5T patent/DK2094684T3/da active
- 2007-10-22 PT PT07871197T patent/PT2094684E/pt unknown
- 2007-10-22 MX MX2009004054A patent/MX2009004054A/es active IP Right Grant
- 2007-10-22 JP JP2009533585A patent/JP5331001B2/ja not_active Expired - Fee Related
- 2007-10-22 AU AU2007329808A patent/AU2007329808B2/en not_active Ceased
- 2007-10-22 CA CA2667372A patent/CA2667372C/en not_active Expired - Fee Related
- 2007-10-22 SI SI200731118T patent/SI2099784T1/sl unknown
- 2007-10-22 BR BRPI0717347-4A2A patent/BRPI0717347A2/pt not_active IP Right Cessation
- 2007-10-22 EA EA200970405A patent/EA015175B1/ru not_active IP Right Cessation
- 2007-10-22 PL PL07871197T patent/PL2094684T3/pl unknown
- 2007-10-22 JP JP2009533586A patent/JP5331002B2/ja not_active Expired - Fee Related
- 2007-10-22 WO PCT/US2007/082042 patent/WO2008070306A2/en not_active Ceased
- 2007-10-22 EP EP07871196A patent/EP2099784B1/en not_active Not-in-force
- 2007-10-22 US US12/441,570 patent/US8168659B2/en not_active Expired - Fee Related
-
2011
- 2011-01-27 CY CY20111100093T patent/CY1111140T1/el unknown