JP2010507585A - 置換インドール - Google Patents
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- JP2010507585A JP2010507585A JP2009533572A JP2009533572A JP2010507585A JP 2010507585 A JP2010507585 A JP 2010507585A JP 2009533572 A JP2009533572 A JP 2009533572A JP 2009533572 A JP2009533572 A JP 2009533572A JP 2010507585 A JP2010507585 A JP 2010507585A
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- deuterium
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- MJCYPBSRKLJZTB-UHFFFAOYSA-N trifluoroborane;dihydrate Chemical compound O.O.FB(F)F MJCYPBSRKLJZTB-UHFFFAOYSA-N 0.000 description 1
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- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 description 1
- 229960001082 trimethoprim Drugs 0.000 description 1
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- LQCLVBQBTUVCEQ-QTFUVMRISA-N troleandomycin Chemical compound O1[C@@H](C)[C@H](OC(C)=O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](C)C(=O)O[C@H](C)[C@H](C)[C@H](OC(C)=O)[C@@H](C)C(=O)[C@@]2(OC2)C[C@H](C)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)OC(C)=O)[C@H]1C LQCLVBQBTUVCEQ-QTFUVMRISA-N 0.000 description 1
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- MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 description 1
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- 150000003751 zinc Chemical class 0.000 description 1
- UGZADUVQMDAIAO-UHFFFAOYSA-L zinc hydroxide Chemical compound [OH-].[OH-].[Zn+2] UGZADUVQMDAIAO-UHFFFAOYSA-L 0.000 description 1
- 229940007718 zinc hydroxide Drugs 0.000 description 1
- 229910021511 zinc hydroxide Inorganic materials 0.000 description 1
- XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1
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- 229960001763 zinc sulfate Drugs 0.000 description 1
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- ZMLPZCGHASSGEA-UHFFFAOYSA-M zinc trifluoromethanesulfonate Chemical compound [Zn+2].[O-]S(=O)(=O)C(F)(F)F ZMLPZCGHASSGEA-UHFFFAOYSA-M 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Liquid Crystal Substances (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85324306P | 2006-10-19 | 2006-10-19 | |
| PCT/US2007/081977 WO2008049116A2 (en) | 2006-10-19 | 2007-10-19 | Substituted indoles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010507585A true JP2010507585A (ja) | 2010-03-11 |
| JP2010507585A5 JP2010507585A5 (cg-RX-API-DMAC7.html) | 2010-12-09 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009533572A Pending JP2010507585A (ja) | 2006-10-19 | 2007-10-19 | 置換インドール |
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|---|---|
| US (1) | US20080103189A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2081893B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2010507585A (cg-RX-API-DMAC7.html) |
| CN (1) | CN101687788A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE502921T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007310949A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0715579A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2666149A1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE602007013440D1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008049116A2 (cg-RX-API-DMAC7.html) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010535187A (ja) * | 2007-08-02 | 2010-11-18 | ジェネリクス・（ユーケー）・リミテッド | 新規な方法 |
| JP2012502038A (ja) * | 2008-09-03 | 2012-01-26 | テバ ファーマシューティカル インダストリーズ リミティド | 免疫機能の２−オキソ−１，２−ジヒドロ−キノリンモジュレーター |
| JP2020503360A (ja) * | 2017-01-04 | 2020-01-30 | アクスサム セラピューティクス インコーポレイテッド | メロキシカムを含有する医薬組成物 |
| JP2024502041A (ja) * | 2020-12-31 | 2024-01-17 | アクスサム セラピューティクス インコーポレイテッド | メロキシカムを含む医薬組成物 |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0916769A2 (pt) | 2008-07-15 | 2017-09-26 | Theracos Inc | derivados de benzilbenzeno deuterados e métodos de uso |
| US20110053968A1 (en) | 2009-06-09 | 2011-03-03 | Auspex Pharmaceuticals, Inc. | Aminopyrimidine inhibitors of tyrosine kinase |
| WO2010144227A2 (en) | 2009-06-12 | 2010-12-16 | Saint-Gobain Ceramics & Plastics, Inc. | High aspect ratio scintillator detector for neutron detection |
| EP2483406A2 (en) | 2009-09-30 | 2012-08-08 | President and Fellows of Harvard College | Methods for modulation of autophagy through the modulation of autophagy-inhibiting gene products |
| CN104447555A (zh) * | 2009-10-26 | 2015-03-25 | 大塚制药株式会社 | 苯并氮杂*化合物 |
| WO2011059080A1 (ja) * | 2009-11-16 | 2011-05-19 | 第一三共株式会社 | 同位体置換されたジアミン誘導体 |
| CA2853729A1 (en) | 2011-10-28 | 2013-05-02 | Board Of Regents, The University Of Texas System | Novel compositions and methods for treating cancer |
| KR20160117596A (ko) | 2014-02-07 | 2016-10-10 | 오스펙스 파마슈티칼스, 인코포레이티드 | 신규 제약 제제 |
| UA123991C2 (uk) | 2015-01-22 | 2021-07-07 | Басф Агро Б.В. | Трикомпонентна гербіцидна комбінація, що включає сафлуфенацил |
| SI3319437T1 (sl) | 2015-07-10 | 2019-08-30 | BASF Agro B.V. | Herbicidni sestavek, ki vsebuje cinmetilin in piroksasulfon |
| EP3319435B1 (en) | 2015-07-10 | 2020-02-19 | BASF Agro B.V. | Herbicidal composition comprising cinmethylin and clomazone |
| US11219212B2 (en) | 2015-07-10 | 2022-01-11 | BASF Agro B.V. | Herbicidal composition comprising cinmethylin and imazamox |
| CN107846893B (zh) | 2015-07-10 | 2024-02-20 | 巴斯夫农业公司 | 包含环庚草醚和苯嘧磺草胺的除草组合物 |
| MY189197A (en) | 2015-07-10 | 2022-01-31 | Basf Agro Bv | Herbicidal composition comprising cinmethylin and acetochlor or pretilachlor |
| PL3319434T3 (pl) | 2015-07-10 | 2019-11-29 | Basf Agro Bv | Kompozycja chwastobójcza zawierająca cynmetylinę i petoksamid |
| CN107846892B (zh) | 2015-07-10 | 2024-02-20 | 巴斯夫农业公司 | 包含环庚草醚和特异性喹啉羧酸的除草组合物 |
| KR102737212B1 (ko) | 2015-07-10 | 2024-12-02 | 바스프 아그로 비.브이. | 제초제 저항성 또는 내성 잡초의 방제 방법 |
| US11219215B2 (en) | 2015-07-10 | 2022-01-11 | BASF Agro B.V. | Herbicidal composition comprising cinmethylin and specific inhibitors of protoporphyrinogen oxidase |
| US10813356B2 (en) | 2015-07-10 | 2020-10-27 | BASF Agro B.V. | Herbicidal composition comprising cinmethylin and dimethenamid |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010535187A (ja) * | 2007-08-02 | 2010-11-18 | ジェネリクス・（ユーケー）・リミテッド | 新規な方法 |
| JP2012502038A (ja) * | 2008-09-03 | 2012-01-26 | テバ ファーマシューティカル インダストリーズ リミティド | 免疫機能の２−オキソ−１，２−ジヒドロ−キノリンモジュレーター |
| JP2015007060A (ja) * | 2008-09-03 | 2015-01-15 | テバ ファーマシューティカル インダストリーズ リミティド | 免疫機能の２−オキソ−１，２−ジヒドロ−キノリンモジュレーター |
| JP2020503360A (ja) * | 2017-01-04 | 2020-01-30 | アクスサム セラピューティクス インコーポレイテッド | メロキシカムを含有する医薬組成物 |
| JP2023144095A (ja) * | 2017-01-04 | 2023-10-06 | アクスサム セラピューティクス インコーポレイテッド | メロキシカム及びリザトリプタンを含有する固体医薬組成物並びにメロキシカム及びリザトリプタンを含有する医薬の製造におけるメロキシカム及びリザトリプタンの使用 |
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| JP2024177375A (ja) * | 2017-01-04 | 2024-12-19 | アクスサム セラピューティクス インコーポレイテッド | メロキシカム及びリザトリプタンを含有する経口固体医薬組成物 |
| JP2024502041A (ja) * | 2020-12-31 | 2024-01-17 | アクスサム セラピューティクス インコーポレイテッド | メロキシカムを含む医薬組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008049116A2 (en) | 2008-04-24 |
| EP2081893A2 (en) | 2009-07-29 |
| EP2081893B1 (en) | 2011-03-23 |
| WO2008049116A3 (en) | 2008-06-05 |
| ATE502921T1 (de) | 2011-04-15 |
| CA2666149A1 (en) | 2008-04-24 |
| DE602007013440D1 (de) | 2011-05-05 |
| CN101687788A (zh) | 2010-03-31 |
| AU2007310949A1 (en) | 2008-04-24 |
| US20080103189A1 (en) | 2008-05-01 |
| BRPI0715579A2 (pt) | 2015-05-26 |
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