JP2010507392A5 - - Google Patents
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- JP2010507392A5 JP2010507392A5 JP2009534633A JP2009534633A JP2010507392A5 JP 2010507392 A5 JP2010507392 A5 JP 2010507392A5 JP 2009534633 A JP2009534633 A JP 2009534633A JP 2009534633 A JP2009534633 A JP 2009534633A JP 2010507392 A5 JP2010507392 A5 JP 2010507392A5
- Authority
- JP
- Japan
- Prior art keywords
- stem cells
- pharmaceutical composition
- composition according
- placental stem
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 claims 32
- 210000004991 placental stem cell Anatomy 0.000 claims 26
- 239000000203 mixture Substances 0.000 claims 15
- 210000000130 stem cell Anatomy 0.000 claims 13
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 claims 10
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 claims 10
- 206010028980 Neoplasm Diseases 0.000 claims 10
- 210000000988 bone and bone Anatomy 0.000 claims 10
- 201000011510 cancer Diseases 0.000 claims 10
- 239000011159 matrix material Substances 0.000 claims 10
- 230000007547 defect Effects 0.000 claims 8
- 208000034578 Multiple myelomas Diseases 0.000 claims 7
- 206010035226 Plasma cell myeloma Diseases 0.000 claims 7
- 230000001464 adherent effect Effects 0.000 claims 7
- 238000000034 method Methods 0.000 claims 7
- 239000000758 substrate Substances 0.000 claims 7
- 206010005949 Bone cancer Diseases 0.000 claims 5
- 208000018084 Bone neoplasm Diseases 0.000 claims 5
- 102100032912 CD44 antigen Human genes 0.000 claims 5
- 102100028967 HLA class I histocompatibility antigen, alpha chain G Human genes 0.000 claims 5
- 108010024164 HLA-G Antigens Proteins 0.000 claims 5
- 101000868273 Homo sapiens CD44 antigen Proteins 0.000 claims 5
- 102000003729 Neprilysin Human genes 0.000 claims 5
- 108090000028 Neprilysin Proteins 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 5
- 229920001436 collagen Polymers 0.000 claims 5
- 102100022464 5'-nucleotidase Human genes 0.000 claims 4
- 102000008186 Collagen Human genes 0.000 claims 4
- 108010035532 Collagen Proteins 0.000 claims 4
- 101000678236 Homo sapiens 5'-nucleotidase Proteins 0.000 claims 4
- 102000008100 Human Serum Albumin Human genes 0.000 claims 4
- 108091006905 Human Serum Albumin Proteins 0.000 claims 4
- 208000003076 Osteolysis Diseases 0.000 claims 4
- 208000029791 lytic metastatic bone lesion Diseases 0.000 claims 4
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 3
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 claims 3
- 102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 claims 3
- 229920002674 hyaluronan Polymers 0.000 claims 3
- 229960003160 hyaluronic acid Drugs 0.000 claims 3
- 208000037819 metastatic cancer Diseases 0.000 claims 3
- 208000011575 metastatic malignant neoplasm Diseases 0.000 claims 3
- 210000005009 osteogenic cell Anatomy 0.000 claims 3
- 102100031585 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Human genes 0.000 claims 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 2
- 208000005243 Chondrosarcoma Diseases 0.000 claims 2
- 201000009047 Chordoma Diseases 0.000 claims 2
- 208000006168 Ewing Sarcoma Diseases 0.000 claims 2
- 101000777636 Homo sapiens ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 Proteins 0.000 claims 2
- 206010029260 Neuroblastoma Diseases 0.000 claims 2
- 208000018420 bone fibrosarcoma Diseases 0.000 claims 2
- 238000002513 implantation Methods 0.000 claims 2
- 239000007972 injectable composition Substances 0.000 claims 2
- 238000001990 intravenous administration Methods 0.000 claims 2
- FZWBNHMXJMCXLU-BLAUPYHCSA-N isomaltotriose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)O1 FZWBNHMXJMCXLU-BLAUPYHCSA-N 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 201000008968 osteosarcoma Diseases 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- 238000007910 systemic administration Methods 0.000 claims 2
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- 229920002307 Dextran Polymers 0.000 claims 1
- 101000800116 Homo sapiens Thy-1 membrane glycoprotein Proteins 0.000 claims 1
- 208000006644 Malignant Fibrous Histiocytoma Diseases 0.000 claims 1
- 206010025557 Malignant fibrous histiocytoma of bone Diseases 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 102100033523 Thy-1 membrane glycoprotein Human genes 0.000 claims 1
- 208000015778 Undifferentiated pleomorphic sarcoma Diseases 0.000 claims 1
- 229960005070 ascorbic acid Drugs 0.000 claims 1
- 235000010323 ascorbic acid Nutrition 0.000 claims 1
- 239000011668 ascorbic acid Substances 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 229910000389 calcium phosphate Inorganic materials 0.000 claims 1
- 239000001506 calcium phosphate Substances 0.000 claims 1
- 235000011010 calcium phosphates Nutrition 0.000 claims 1
- 239000000919 ceramic Substances 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims 1
- 229960003957 dexamethasone Drugs 0.000 claims 1
- 229940119744 dextran 40 Drugs 0.000 claims 1
- 201000008825 fibrosarcoma of bone Diseases 0.000 claims 1
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000011707 mineral Substances 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 230000003169 placental effect Effects 0.000 claims 1
- 208000018417 undifferentiated high grade pleomorphic sarcoma of bone Diseases 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85397106P | 2006-10-23 | 2006-10-23 | |
| US85562906P | 2006-10-30 | 2006-10-30 | |
| US99702207P | 2007-09-28 | 2007-09-28 | |
| PCT/US2007/022545 WO2008051568A2 (en) | 2006-10-23 | 2007-10-23 | Methods and compositions for treatment of bone defects with placental cell populations |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013110672A Division JP2013216661A (ja) | 2006-10-23 | 2013-05-27 | 胎盤細胞集団で骨欠損を治療するための方法及び組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010507392A JP2010507392A (ja) | 2010-03-11 |
| JP2010507392A5 true JP2010507392A5 (cg-RX-API-DMAC7.html) | 2010-12-16 |
Family
ID=39325178
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009534633A Pending JP2010507392A (ja) | 2006-10-23 | 2007-10-23 | 胎盤細胞集団で骨欠損を治療するための方法及び組成物 |
| JP2013110672A Pending JP2013216661A (ja) | 2006-10-23 | 2013-05-27 | 胎盤細胞集団で骨欠損を治療するための方法及び組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013110672A Pending JP2013216661A (ja) | 2006-10-23 | 2013-05-27 | 胎盤細胞集団で骨欠損を治療するための方法及び組成物 |
Country Status (16)
| Country | Link |
|---|---|
| US (5) | US8562972B2 (cg-RX-API-DMAC7.html) |
| EP (5) | EP2418271A3 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2010507392A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20090076989A (cg-RX-API-DMAC7.html) |
| CN (3) | CN101631852A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007309447B2 (cg-RX-API-DMAC7.html) |
| CA (2) | CA2850793A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK2084268T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2709205T3 (cg-RX-API-DMAC7.html) |
| IL (1) | IL198008A (cg-RX-API-DMAC7.html) |
| MX (1) | MX2009004238A (cg-RX-API-DMAC7.html) |
| NZ (3) | NZ606814A (cg-RX-API-DMAC7.html) |
| PL (1) | PL2084268T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2084268T (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008051568A2 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA200902233B (cg-RX-API-DMAC7.html) |
Families Citing this family (85)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7700353B2 (en) * | 1998-07-22 | 2010-04-20 | E-P Therapeutics, Inc. | Compositions and methods for inducing apoptosis in tumor cells |
| KR100915482B1 (ko) | 2000-12-06 | 2009-09-03 | 하리리 로버트 제이 | 태반 줄기 세포의 회수 방법 |
| US7311905B2 (en) * | 2002-02-13 | 2007-12-25 | Anthrogenesis Corporation | Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells |
| ES2548591T3 (es) | 2001-02-14 | 2015-10-19 | Anthrogenesis Corporation | Placenta post-parto de mamífero, su uso y células madre placentarias de la misma |
| US7498171B2 (en) | 2002-04-12 | 2009-03-03 | Anthrogenesis Corporation | Modulation of stem and progenitor cell differentiation, assays, and uses thereof |
| BR0316695A (pt) * | 2002-11-26 | 2005-10-18 | Anthrogenesis Corp | Unidade citoterapêutica, kit para tratamento, método de tratamento de uma enfermidade, biblioteca de unidades citoterapêuticas e método de tratamento de um paciente |
| ITRM20030376A1 (it) | 2003-07-31 | 2005-02-01 | Univ Roma | Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia. |
| NZ550027A (en) * | 2004-03-26 | 2009-03-31 | Celgene Corp | Systems and methods for providing a stem cell bank |
| US11660317B2 (en) | 2004-11-08 | 2023-05-30 | The Johns Hopkins University | Compositions comprising cardiosphere-derived cells for use in cell therapy |
| MX343814B (es) | 2005-10-13 | 2016-11-24 | Anthrogenesis Corp | Inmunomodulación usando celulas madre de la placenta. |
| JP5203212B2 (ja) * | 2005-10-13 | 2013-06-05 | アントフロゲネシス コーポレーション | 胎盤由来幹細胞からのオリゴデンドロサイトの産生 |
| EP1976978A2 (en) * | 2005-12-29 | 2008-10-08 | Anthrogenesis Corporation | Co-culture of placental stem cells and stem cells from a second source |
| JP2009521931A (ja) | 2005-12-29 | 2009-06-11 | アントフロゲネシス コーポレーション | 胎盤幹細胞を収集及び保存するための改善された組成物、及び該組成物の使用方法 |
| EP2471903B1 (en) | 2005-12-29 | 2018-02-14 | Anthrogenesis Corporation | Placental stem cell populations |
| US20090318355A1 (en) * | 2006-02-15 | 2009-12-24 | Chen Thomas T | Compositions and methods for promoting tissue repair and wound healing |
| US20090221072A1 (en) * | 2006-02-15 | 2009-09-03 | Chen Thomas T | Compositions and methods for modulating cell differentiation |
| US7993918B2 (en) | 2006-08-04 | 2011-08-09 | Anthrogenesis Corporation | Tumor suppression using placental stem cells |
| EP2418271A3 (en) | 2006-10-23 | 2015-09-30 | Anthrogenesis Corporation | Methods and compositions for treatment of bone defects with placental cell populations |
| CN101657206B (zh) | 2007-02-12 | 2013-07-03 | 人类起源公司 | 利用胎盘干细胞治疗炎性疾病 |
| JP2010518812A (ja) | 2007-02-12 | 2010-06-03 | アンスロジェネシス コーポレーション | 接着性胎盤幹細胞由来の肝細胞および軟骨細胞、ならびにｃｄ３４＋、ｃｄ４５−胎盤幹細胞の濃縮細胞集団 |
| US9200253B1 (en) | 2007-08-06 | 2015-12-01 | Anthrogenesis Corporation | Method of producing erythrocytes |
| EP2591789B2 (en) * | 2007-09-19 | 2022-07-20 | Pluristem Ltd. | Adherent cells from adipose or placenta tissues and use thereof in therapy |
| CN101978045A (zh) * | 2007-09-26 | 2011-02-16 | 细胞基因细胞疗法公司 | 来自人胎盘灌洗液的血管生成细胞 |
| CN101878034B (zh) | 2007-09-28 | 2013-11-20 | 细胞基因细胞疗法公司 | 使用人胎盘灌洗液和人来自胎盘的中间体自然杀伤细胞的肿瘤抑制 |
| JP5950577B2 (ja) | 2008-08-20 | 2016-07-13 | アンスロジェネシス コーポレーション | 単離胎盤細胞を使用した脳卒中の治療 |
| KR20240052847A (ko) | 2008-08-20 | 2024-04-23 | 셀룰래리티 인코포레이티드 | 개선된 세포 조성물 및 그의 제조 방법 |
| US8728805B2 (en) * | 2008-08-22 | 2014-05-20 | Anthrogenesis Corporation | Methods and compositions for treatment of bone defects with placental cell populations |
| WO2010040262A1 (zh) * | 2008-10-10 | 2010-04-15 | 深圳市嘉天源生物科技有限公司 | 分离动物胚胎间质性干细胞并提取其分泌物的方法 |
| NZ592726A (en) * | 2008-11-19 | 2012-12-21 | Anthrogenesis Corp | Amnion derived adherent cells |
| AR077369A1 (es) | 2009-07-02 | 2011-08-24 | Anthrogenesis Corp | Metodopara producir eritrocitos sin celulas alimentadoras |
| US8926552B2 (en) | 2009-08-12 | 2015-01-06 | Medtronic, Inc. | Particle delivery |
| WO2011029102A2 (en) * | 2009-09-07 | 2011-03-10 | The Regents Of The University Of Colorado, A Body Corporate | Cd117+cells and uses thereof |
| ES2646750T3 (es) * | 2010-01-26 | 2017-12-15 | Anthrogenesis Corporation | Tratamiento de cánceres relacionados con hueso utilizando células madre placentarias |
| CA3175739A1 (en) | 2010-02-18 | 2011-08-25 | Osiris Therapeutics, Inc. | Methods of manufacture of therapeutic products comprising vitalized placental dispersions |
| LT2556145T (lt) | 2010-04-07 | 2016-11-10 | Anthrogenesis Corporation | Angiogenezė naudojant placentos kamienines ląsteles |
| MX2012011543A (es) | 2010-04-08 | 2013-05-06 | Anthrogenesis Corp | Tratamiento de sarcoidosis empleando celulas madre placentarias. |
| US9845457B2 (en) | 2010-04-30 | 2017-12-19 | Cedars-Sinai Medical Center | Maintenance of genomic stability in cultured stem cells |
| US9249392B2 (en) * | 2010-04-30 | 2016-02-02 | Cedars-Sinai Medical Center | Methods and compositions for maintaining genomic stability in cultured stem cells |
| US10130736B1 (en) | 2010-05-14 | 2018-11-20 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US9352003B1 (en) | 2010-05-14 | 2016-05-31 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US8883210B1 (en) | 2010-05-14 | 2014-11-11 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| JP5996533B2 (ja) | 2010-07-13 | 2016-09-21 | アントフロゲネシス コーポレーション | ナチュラルキラー細胞を生成させる方法 |
| US8679474B2 (en) | 2010-08-04 | 2014-03-25 | StemBios Technologies, Inc. | Somatic stem cells |
| AU2011317203B2 (en) * | 2010-10-18 | 2016-10-20 | Sunshine Life Science & Technology Corp. | Human multipotent embryonic stem cell-like progenitor cells |
| WO2012068378A1 (en) * | 2010-11-17 | 2012-05-24 | Wake Forest University Health Sciences | Stem cell differentiation using keratin biomaterials |
| EP2640408B1 (en) * | 2010-11-17 | 2016-05-25 | Wake Forest University Health Sciences | Keratin compositions for treatment of bone deficiency or injury |
| FR2967579B1 (fr) * | 2010-11-23 | 2013-11-22 | Ets Francais Du Sang | Utilisation d'une isoforme d'hla-g comme agent anti-resorption osseuse |
| US8969315B2 (en) | 2010-12-31 | 2015-03-03 | Anthrogenesis Corporation | Enhancement of placental stem cell potency using modulatory RNA molecules |
| KR101395214B1 (ko) * | 2011-04-18 | 2014-05-16 | 고려대학교 산학협력단 | 태반유래세포에 조건화된 배양 배지, 및 이를 이용한 무동물 및 무지지세포 줄기세포 배양 방법 |
| WO2012149486A1 (en) | 2011-04-28 | 2012-11-01 | Tissuetech, Inc. | Methods of modulating bone remodeling |
| EP2714059B1 (en) | 2011-06-01 | 2018-10-03 | Celularity, Inc. | Treatment of pain using placental stem cells |
| CN103796659A (zh) * | 2011-07-13 | 2014-05-14 | 车比奥及戴奥斯泰有限公司 | 包含胶原、透明质酸衍生物和哺乳动物脐带来源干细胞的软骨细胞治疗物 |
| US9925221B2 (en) | 2011-09-09 | 2018-03-27 | Celularity, Inc. | Treatment of amyotrophic lateral sclerosis using placental stem cells |
| US20130309210A1 (en) * | 2012-05-18 | 2013-11-21 | Regen Biopharma, Inc | Acceleration of hematopoietic reconstitution by placental endothelial and endothelial progenitor cells |
| WO2013184527A1 (en) | 2012-06-05 | 2013-12-12 | Capricor, Inc. | Optimized methods for generation of cardiac stem cells from cardiac tissue and their use in cardiac therapy |
| US9828603B2 (en) | 2012-08-13 | 2017-11-28 | Cedars Sinai Medical Center | Exosomes and micro-ribonucleic acids for tissue regeneration |
| WO2014089268A2 (en) | 2012-12-06 | 2014-06-12 | StemBios Technologies, Inc. | Lgr5+ somatic stem cells |
| US9763983B2 (en) | 2013-02-05 | 2017-09-19 | Anthrogenesis Corporation | Natural killer cells from placenta |
| CN103173405B (zh) * | 2013-03-21 | 2017-11-07 | 北京京蒙高科干细胞技术有限公司 | 一种人胎盘成肌纤维母细胞的简易分离及鉴定方法 |
| JP6635505B2 (ja) * | 2013-11-01 | 2020-01-29 | 国立大学法人京都大学 | 新規軟骨細胞誘導方法 |
| RU2016123361A (ru) * | 2013-11-15 | 2017-12-20 | Антродженезис Корпорейшн | Композиции, включающие клетки плацентарного перфузата человека |
| JP6486948B2 (ja) | 2014-01-08 | 2019-03-20 | サムスン ライフ パブリック ウェルフェア ファウンデーション | 純粋栄養膜層から由来した幹細胞及びそれを含む細胞治療剤 |
| ES2858648T3 (es) | 2014-01-08 | 2021-09-30 | Samsung Life Public Welfare Foundation | Células madre derivadas de la porción basal de la capa de trofoblastos coriónicos y terapia celular que comprende las mismas |
| GB201406716D0 (en) * | 2014-04-15 | 2014-05-28 | Insphero Ag | Method of preparing cells for 3D tissue culture |
| WO2015175776A1 (en) * | 2014-05-14 | 2015-11-19 | NuTech Medical, Inc. | Placental membrane preparations and methods of making and using same for regenerating cartilage and spinal intervertebral discs |
| EP3200808B1 (en) | 2014-10-03 | 2024-07-31 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy |
| HK1232131A1 (zh) * | 2014-11-19 | 2018-01-05 | 干细胞生物科技公司 | 用於治疗骨骼缺损的体干细胞 |
| US20160159869A1 (en) * | 2014-12-09 | 2016-06-09 | Northwestern University | Bmp-2-binding peptide amphiphile nanofibers |
| WO2016187413A1 (en) | 2015-05-21 | 2016-11-24 | Musculoskeletal Transplant Foundation | Modified demineralized cortical bone fibers |
| BR112017025586A2 (pt) * | 2015-05-28 | 2018-08-07 | Celularity Inc | células tronco derivadas da placenta para restaurar o mecanismo regenerativo, corrigir defeitos proteômicos e prolongar a vida útil |
| US11253551B2 (en) | 2016-01-11 | 2022-02-22 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction |
| WO2017210652A1 (en) | 2016-06-03 | 2017-12-07 | Cedars-Sinai Medical Center | Cdc-derived exosomes for treatment of ventricular tachyarrythmias |
| US11541078B2 (en) | 2016-09-20 | 2023-01-03 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders |
| CA3059910A1 (en) | 2017-04-19 | 2018-10-25 | Cedars-Sinai Medical Center | Methods and compositions for treating skeletal muscular dystrophy |
| US12031136B2 (en) | 2017-10-24 | 2024-07-09 | Oklahoma Medical Research Foundation | Treatment for skeletal diseases caused by intracellular protein trafficking defects |
| CN111727238B (zh) * | 2017-10-27 | 2024-06-25 | 阿里斯制药有限公司 | 非人动物胎儿组织提取物、生产提取物的方法及其用途 |
| EP3727351A4 (en) | 2017-12-20 | 2021-10-06 | Cedars-Sinai Medical Center | MANIPULATED EXTRACELLULAR VESICLES FOR ENHANCED RELEASE INTO TISSUE |
| KR102413235B1 (ko) * | 2017-12-22 | 2022-06-24 | 고려대학교 산학협력단 | 체세포에서 전능성 줄기세포로의 역분화 유도용 태반유래세포 조건화 배지 및 이를 이용한 역분화 유도 방법 |
| CN108324993B (zh) * | 2018-01-15 | 2020-11-03 | 朱剑虹 | 一种诱导毛发再生的干细胞复合体、其制备方法及应用 |
| US12146137B2 (en) | 2018-02-05 | 2024-11-19 | Cedars-Sinai Medical Center | Methods for therapeutic use of exosomes and Y-RNAS |
| US20220160787A1 (en) * | 2019-03-15 | 2022-05-26 | Celularity Inc. | Placenta derived adherent cells for improved xenoplantation |
| CN114096289B (zh) * | 2019-10-30 | 2023-09-01 | 爱恩斯生物科技(昆山)有限公司 | 含有骨无机质成分的复合脱钙骨组合物及其制备方法 |
| CN115282339B (zh) * | 2022-07-28 | 2023-02-28 | 四川大学 | 一种交联透明质酸/羟基磷灰石可注射材料、制备方法及应用 |
| KR102739922B1 (ko) * | 2024-02-22 | 2024-12-11 | 유한회사 스템메디케어 | 면역관용화된 태아 줄기세포 유래 세포외소포의 골관절염 치료용 약학조성물로서의 용도, 세포외소포 제조방법 및 이를 이용한 골관절염 치료용 조성물 |
| CN118421565B (zh) * | 2024-03-21 | 2024-11-29 | 中国人民解放军军事科学院军事医学研究院 | 重组骨软骨干细胞及其制备方法与应用 |
Family Cites Families (135)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080A (en) * | 1858-04-27 | Improvement in harvesters | ||
| US4798824A (en) | 1985-10-03 | 1989-01-17 | Wisconsin Alumni Research Foundation | Perfusate for the preservation of organs |
| US5863531A (en) * | 1986-04-18 | 1999-01-26 | Advanced Tissue Sciences, Inc. | In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework |
| US5192553A (en) | 1987-11-12 | 1993-03-09 | Biocyte Corporation | Isolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood and methods of therapeutic use |
| US5004681B1 (en) | 1987-11-12 | 2000-04-11 | Biocyte Corp | Preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood |
| EP0747485B1 (en) | 1989-11-06 | 1998-12-02 | Cell Genesys, Inc. | Production of proteins using homologous recombination |
| US5197985A (en) * | 1990-11-16 | 1993-03-30 | Caplan Arnold I | Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells |
| US5226914A (en) * | 1990-11-16 | 1993-07-13 | Caplan Arnold I | Method for treating connective tissue disorders |
| US5733542A (en) * | 1990-11-16 | 1998-03-31 | Haynesworth; Stephen E. | Enhancing bone marrow engraftment using MSCS |
| US5486359A (en) | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
| US5811094A (en) | 1990-11-16 | 1998-09-22 | Osiris Therapeutics, Inc. | Connective tissue regeneration using human mesenchymal stem cell preparations |
| US5190556A (en) | 1991-03-19 | 1993-03-02 | O.B. Tech, Inc. | Cord cutter sampler |
| US5356373A (en) | 1991-11-15 | 1994-10-18 | Miles Inc. | Method and apparatus for autologous transfusions in premature infants |
| US5552267A (en) | 1992-04-03 | 1996-09-03 | The Trustees Of Columbia University In The City Of New York | Solution for prolonged organ preservation |
| US5372581A (en) | 1993-07-21 | 1994-12-13 | Minneapolis Children's Services Corporation | Method and apparatus for placental blood collection |
| IL107483A0 (en) | 1993-11-03 | 1994-02-27 | Yeda Res & Dev | Bone marrow transplantation |
| US6288030B1 (en) * | 1993-12-22 | 2001-09-11 | Amgen Inc. | Stem cell factor formulations and methods |
| US5942496A (en) | 1994-02-18 | 1999-08-24 | The Regent Of The University Of Michigan | Methods and compositions for multiple gene transfer into bone cells |
| US6174333B1 (en) * | 1994-06-06 | 2001-01-16 | Osiris Therapeutics, Inc. | Biomatrix for soft tissue regeneration using mesenchymal stem cells |
| EP0952792B1 (en) * | 1994-06-06 | 2003-08-27 | Case Western Reserve University | Biomatrix for tissue regeneration |
| US5516532A (en) * | 1994-08-05 | 1996-05-14 | Children's Medical Center Corporation | Injectable non-immunogenic cartilage and bone preparation |
| US5736396A (en) * | 1995-01-24 | 1998-04-07 | Case Western Reserve University | Lineage-directed induction of human mesenchymal stem cell differentiation |
| US5716616A (en) * | 1995-03-28 | 1998-02-10 | Thomas Jefferson University | Isolated stromal cells for treating diseases, disorders or conditions characterized by bone defects |
| US5830708A (en) | 1995-06-06 | 1998-11-03 | Advanced Tissue Sciences, Inc. | Methods for production of a naturally secreted extracellular matrix |
| US5800539A (en) | 1995-11-08 | 1998-09-01 | Emory University | Method of allogeneic hematopoietic stem cell transplantation without graft failure or graft vs. host disease |
| AU1119397A (en) * | 1995-11-14 | 1997-06-05 | Regents Of The University Of Minnesota | Ex vivo culture of stem cells |
| JP3781433B2 (ja) * | 1995-11-16 | 2006-05-31 | ケース ウエスターン リザーブ ユニバーシティ | ヒト間葉幹細胞の試験管内軟骨形成誘導 |
| JP2000508911A (ja) * | 1996-04-19 | 2000-07-18 | オシリス セラピューティクス，インコーポレイテッド | 間葉幹細胞を用いる骨の再生および増強 |
| US5827740A (en) | 1996-07-30 | 1998-10-27 | Osiris Therapeutics, Inc. | Adipogenic differentiation of human mesenchymal stem cells |
| US6358737B1 (en) * | 1996-07-31 | 2002-03-19 | Board Of Regents, The University Of Texas System | Osteocyte cell lines |
| US5919702A (en) * | 1996-10-23 | 1999-07-06 | Advanced Tissue Science, Inc. | Production of cartilage tissue using cells isolated from Wharton's jelly |
| AU749675B2 (en) * | 1998-03-13 | 2002-07-04 | Mesoblast International Sarl | Uses for human non-autologous mesenchymal stem cells |
| US6835377B2 (en) | 1998-05-13 | 2004-12-28 | Osiris Therapeutics, Inc. | Osteoarthritis cartilage regeneration |
| US6387367B1 (en) * | 1998-05-29 | 2002-05-14 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
| US6713245B2 (en) * | 1998-07-06 | 2004-03-30 | Diacrin, Inc. | Methods for storing neural cells such that they are suitable for transplantation |
| CA2370330C (en) | 1999-04-16 | 2009-01-20 | Wm. Marsh Rice University | Biodegradable poly(propylene fumarate) networks cross linked with poly(propylene fumarate)-diacrylate macromers |
| US6355699B1 (en) | 1999-06-30 | 2002-03-12 | Ethicon, Inc. | Process for manufacturing biomedical foams |
| US8147824B2 (en) | 1999-08-05 | 2012-04-03 | Athersys, Inc. | Immunomodulatory properties of multipotent adult progenitor cells and uses thereof |
| US8075881B2 (en) * | 1999-08-05 | 2011-12-13 | Regents Of The University Of Minnesota | Use of multipotent adult stem cells in treatment of myocardial infarction and congestive heart failure |
| US7015037B1 (en) | 1999-08-05 | 2006-03-21 | Regents Of The University Of Minnesota | Multiponent adult stem cells and methods for isolation |
| US6685936B2 (en) * | 1999-10-12 | 2004-02-03 | Osiris Therapeutics, Inc. | Suppressor cells induced by culture with mesenchymal stem cells for treatment of immune responses in transplantation |
| US6962789B2 (en) | 2000-01-12 | 2005-11-08 | Ventana Medical Systems, Inc. | Method for quantitating a protein by image analysis |
| WO2001075094A1 (en) | 2000-04-04 | 2001-10-11 | Thomas Jefferson University | Application of myeloid-origin cells to the nervous system |
| KR100915482B1 (ko) | 2000-12-06 | 2009-09-03 | 하리리 로버트 제이 | 태반 줄기 세포의 회수 방법 |
| US20080152629A1 (en) * | 2000-12-06 | 2008-06-26 | James Edinger | Placental stem cell populations |
| US7311905B2 (en) * | 2002-02-13 | 2007-12-25 | Anthrogenesis Corporation | Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells |
| EP1491093B1 (en) * | 2001-02-14 | 2013-07-31 | ABT Holding Company | Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof |
| EP2336299A1 (en) * | 2001-02-14 | 2011-06-22 | Anthrogenesis Corporation | Post-partum mammalian placenta, its use and placental stem cells therefrom |
| ES2548591T3 (es) | 2001-02-14 | 2015-10-19 | Anthrogenesis Corporation | Placenta post-parto de mamífero, su uso y células madre placentarias de la misma |
| CA2396536A1 (en) | 2001-08-10 | 2003-02-10 | Saiko Uchida | Human stem cells originated from human amniotic mesenchymal cell layer |
| WO2003018780A1 (en) * | 2001-08-27 | 2003-03-06 | Advanced Cell Technology, Inc. | De-differentiation and re-differentiation of somatic cells and production of cells for cell therapies |
| EP1288293A1 (en) | 2001-08-30 | 2003-03-05 | Norio Sakuragawa | Human neural stem cells originated from human amniotic mesenchymal cell layer |
| US9969980B2 (en) | 2001-09-21 | 2018-05-15 | Garnet Biotherapeutics | Cell populations which co-express CD49c and CD90 |
| US8021876B2 (en) | 2001-11-15 | 2011-09-20 | Children's Medical Center Corporation | Methods of isolation, expansion and differentiation of fetal stem cells from chorionic villus, amniotic fluid, and placenta and therapeutic uses thereof |
| US7799324B2 (en) | 2001-12-07 | 2010-09-21 | Geron Corporation | Using undifferentiated embryonic stem cells to control the immune system |
| JP3934539B2 (ja) | 2001-12-12 | 2007-06-20 | 独立行政法人科学技術振興機構 | 胎盤等由来の成体又は生後組織の前駆細胞 |
| EP1458854B1 (en) * | 2001-12-21 | 2010-04-14 | Mount Sinai Hospital | Cellular compositions and methods of making and using them |
| NZ534643A (en) * | 2002-02-13 | 2010-06-25 | Anthrogenesis Corp | Embryonic-like stem cells derived from post-partum mammalian placenta and uses and methods of treatment using said cells |
| US7736892B2 (en) * | 2002-02-25 | 2010-06-15 | Kansas State University Research Foundation | Cultures, products and methods using umbilical cord matrix cells |
| US20030161818A1 (en) * | 2002-02-25 | 2003-08-28 | Kansas State University Research Foundation | Cultures, products and methods using stem cells |
| US20030187515A1 (en) * | 2002-03-26 | 2003-10-02 | Hariri Robert J. | Collagen biofabric and methods of preparing and using the collagen biofabric |
| AU2003221173A1 (en) * | 2002-03-27 | 2003-10-08 | Asahi Kasei Kabushiki Kaisha | Placenta-origin mesenchymal cells and medicinal use thereof |
| US20050118715A1 (en) * | 2002-04-12 | 2005-06-02 | Hariri Robert J. | Modulation of stem and progenitor cell differentiation, assays, and uses thereof |
| US7498171B2 (en) | 2002-04-12 | 2009-03-03 | Anthrogenesis Corporation | Modulation of stem and progenitor cell differentiation, assays, and uses thereof |
| JP2005523328A (ja) | 2002-04-19 | 2005-08-04 | ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション | 胎盤由来の幹細胞及びその使用 |
| US20040161419A1 (en) * | 2002-04-19 | 2004-08-19 | Strom Stephen C. | Placental stem cells and uses thereof |
| KR20050008757A (ko) | 2002-05-30 | 2005-01-21 | 셀진 코포레이션 | 세포 분화를 조절하고 골수증식성 질환 및 골수형성이상증후군을 치료하기 위하여 ｊｎｋ 또는 ｍｋｋ 저해제를사용하는 방법 |
| US7422736B2 (en) | 2002-07-26 | 2008-09-09 | Food Industry Research And Development Institute | Somatic pluripotent cells |
| EP1527161B1 (fr) | 2002-07-31 | 2015-10-28 | Yves Saint-Laurent Parfums | Cellules souches issues de tissu adipeux et cellules differenciees issues de ces cellules |
| BR0316695A (pt) | 2002-11-26 | 2005-10-18 | Anthrogenesis Corp | Unidade citoterapêutica, kit para tratamento, método de tratamento de uma enfermidade, biblioteca de unidades citoterapêuticas e método de tratamento de um paciente |
| CA2515594A1 (en) * | 2003-02-13 | 2004-08-26 | Anthrogenesis Corporation | Use of umbilical cord blood to treat individuals having a disease, disorder or condition |
| WO2004087896A2 (en) | 2003-03-31 | 2004-10-14 | Pfizer Products Inc. | Hepatocyte differentiation of stem cells |
| US7875272B2 (en) | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
| PL1641916T3 (pl) * | 2003-06-27 | 2016-08-31 | Depuy Synthes Products Inc | Regeneracja i naprawa tkanki nerwowej z wykorzystaniem komórek poporodowych |
| CN1565643A (zh) * | 2003-07-03 | 2005-01-19 | 中国人民解放军军事医学科学院基础医学研究所 | 一种基于骨髓间充质干细胞的组织工程化软骨 |
| US7569385B2 (en) * | 2003-08-14 | 2009-08-04 | The Regents Of The University Of California | Multipotent amniotic fetal stem cells |
| US20050089513A1 (en) * | 2003-10-28 | 2005-04-28 | Norio Sakuragawa | Side population cells originated from human amnion and their uses |
| JP2005151907A (ja) | 2003-11-27 | 2005-06-16 | Shigeo Saito | 胎盤又は羊膜由来ヒト幹細胞及びその樹立方法並びに臓器への分化誘導方法 |
| EP1694328A4 (en) * | 2003-12-02 | 2010-02-17 | Celgene Corp | METHOD AND COMPOSITIONS FOR THE TREATMENT AND SUPPLY OF HEMOGLOBINOPATHY AND ANEMIA |
| US20050176139A1 (en) * | 2004-01-12 | 2005-08-11 | Yao-Chang Chen | Placental stem cell and methods thereof |
| US20050266391A1 (en) | 2004-01-15 | 2005-12-01 | Bennett Brydon L | Methods for preserving tissue |
| NZ550027A (en) | 2004-03-26 | 2009-03-31 | Celgene Corp | Systems and methods for providing a stem cell bank |
| WO2005105992A1 (en) | 2004-04-21 | 2005-11-10 | New York Eye & Ear Infirmary | Chondrocyte culture formulations |
| JP2006006249A (ja) * | 2004-06-28 | 2006-01-12 | Hiroshima Univ | 羊膜由来細胞の培養方法及びその利用 |
| US7244759B2 (en) * | 2004-07-28 | 2007-07-17 | Celgene Corporation | Isoindoline compounds and methods of making and using the same |
| WO2006015214A2 (en) | 2004-07-29 | 2006-02-09 | Steenblock Research Institute, Inc. | Umbilical cord stem cell composition & method of treating neurological diseases |
| US7909806B2 (en) | 2004-09-23 | 2011-03-22 | Anthrogenesis Corporation | Cord blood and placenta collection kit |
| US7147626B2 (en) * | 2004-09-23 | 2006-12-12 | Celgene Corporation | Cord blood and placenta collection kit |
| WO2006083394A2 (en) * | 2004-12-21 | 2006-08-10 | Ethicon, Inc. | Postpartum cells derived from placental tissue, and methods of making, culturing, and using the same |
| WO2006101548A2 (en) | 2004-12-21 | 2006-09-28 | Ethicon, Inc. | Postpartum cells derived from umbilical cord tissue, and methods of making, culturing, and using the same |
| WO2006071778A2 (en) | 2004-12-23 | 2006-07-06 | Ethicon Incorporated | Treatment of parkinson's disease and related disorders using postpartum derived cells |
| WO2006071773A2 (en) * | 2004-12-23 | 2006-07-06 | Ethicon Incoporated | Treatment of osteochondral diseases using postpartum-derived cells and products thereof |
| AU2006203990B2 (en) * | 2005-01-07 | 2011-08-11 | Wake Forest University Health Sciences | Regeneration of pancreatic islets by amniotic fluid stem cell therapy |
| AU2006202209B2 (en) * | 2005-05-27 | 2011-04-14 | Lifescan, Inc. | Amniotic fluid derived cells |
| EP1893249A2 (en) * | 2005-06-10 | 2008-03-05 | Celgene Corporation | Human placental collagen compositions, processes for their preparation, methods of their use and kits comprising the compositions |
| WO2007005807A2 (en) * | 2005-06-30 | 2007-01-11 | Anthrogenesis Corporation | Repair of tympanic membrane using placenta derived collagen biofabric |
| WO2007009062A2 (en) * | 2005-07-13 | 2007-01-18 | Anthrogenesis Corporation | Treatment of leg ulcers using placenta derived collagen biofabric |
| US20070021762A1 (en) * | 2005-07-13 | 2007-01-25 | Qing Liu | Ocular plug formed from placenta derived collagen biofabric |
| WO2007011693A2 (en) * | 2005-07-14 | 2007-01-25 | Medistem Laboratories, Inc. | Compositions of placentally-derived stem cells for the treatment of cancer |
| US20080226612A1 (en) | 2005-08-19 | 2008-09-18 | Bio Regenerate, Inc. | Compositions of Cells Enriched for Combinations of Various Stem and Progenitor Cell Populations, Methods of Use Thereof and Methods of Private Banking Thereof |
| JP5203212B2 (ja) | 2005-10-13 | 2013-06-05 | アントフロゲネシス コーポレーション | 胎盤由来幹細胞からのオリゴデンドロサイトの産生 |
| MX343814B (es) * | 2005-10-13 | 2016-11-24 | Anthrogenesis Corp | Inmunomodulación usando celulas madre de la placenta. |
| US9175261B2 (en) | 2005-12-16 | 2015-11-03 | DePuy Synthes Products, Inc. | Human umbilical cord tissue cells for inhibiting adverse immune response in histocompatibility-mismatched transplantation |
| JP5179376B2 (ja) * | 2005-12-19 | 2013-04-10 | エシコン・インコーポレイテッド | ローラーボトルでの分娩後取り出し細胞の体外増殖 |
| JP2009520466A (ja) | 2005-12-22 | 2009-05-28 | エニス，ジエーン | 凍結臍帯組織由来の生存可能な細胞 |
| JP5599568B2 (ja) * | 2005-12-28 | 2014-10-01 | エシコン・インコーポレイテッド | 分娩後由来細胞を用いた末梢血管疾患の治療 |
| JP2009521931A (ja) | 2005-12-29 | 2009-06-11 | アントフロゲネシス コーポレーション | 胎盤幹細胞を収集及び保存するための改善された組成物、及び該組成物の使用方法 |
| EP1976978A2 (en) | 2005-12-29 | 2008-10-08 | Anthrogenesis Corporation | Co-culture of placental stem cells and stem cells from a second source |
| EP2471903B1 (en) | 2005-12-29 | 2018-02-14 | Anthrogenesis Corporation | Placental stem cell populations |
| US20070253931A1 (en) | 2006-01-12 | 2007-11-01 | Osiris Therapeutics, Inc. | Use of mesenchymal stem cells for treating genetic diseases and disorders |
| NZ727755A (en) | 2006-01-23 | 2023-01-27 | Abt Holding Co | Mapc therapeutics without adjunctive immunosuppressive treatment |
| EP1845154A1 (en) | 2006-04-12 | 2007-10-17 | RNL Bio Co., Ltd. | Multipotent stem cells derived from placenta tissue and cellular therapeutic agents comprising the same |
| EP2035552A2 (en) * | 2006-06-09 | 2009-03-18 | Anthrogenesis Corporation | Placental niche and use thereof to culture stem cells |
| US20070287176A1 (en) | 2006-06-13 | 2007-12-13 | Alireza Rezania | Chorionic villus derived cells |
| US7993918B2 (en) | 2006-08-04 | 2011-08-09 | Anthrogenesis Corporation | Tumor suppression using placental stem cells |
| US8105634B2 (en) * | 2006-08-15 | 2012-01-31 | Anthrogenesis Corporation | Umbilical cord biomaterial for medical use |
| US8122763B2 (en) * | 2006-09-01 | 2012-02-28 | Avair, Llc | Breathing gas supply visual broadcast apparatus |
| US20080131522A1 (en) * | 2006-10-03 | 2008-06-05 | Qing Liu | Use of placental biomaterial for ocular surgery |
| WO2008060377A2 (en) * | 2006-10-04 | 2008-05-22 | Anthrogenesis Corporation | Placental or umbilical cord tissue compositions |
| CN104623642A (zh) * | 2006-10-06 | 2015-05-20 | 人类起源公司 | 天然(端肽)胎盘胶原组合物 |
| EP2418271A3 (en) | 2006-10-23 | 2015-09-30 | Anthrogenesis Corporation | Methods and compositions for treatment of bone defects with placental cell populations |
| JP2010518812A (ja) | 2007-02-12 | 2010-06-03 | アンスロジェネシス コーポレーション | 接着性胎盤幹細胞由来の肝細胞および軟骨細胞、ならびにｃｄ３４＋、ｃｄ４５−胎盤幹細胞の濃縮細胞集団 |
| CN101657206B (zh) | 2007-02-12 | 2013-07-03 | 人类起源公司 | 利用胎盘干细胞治疗炎性疾病 |
| US9200253B1 (en) | 2007-08-06 | 2015-12-01 | Anthrogenesis Corporation | Method of producing erythrocytes |
| CN101978045A (zh) * | 2007-09-26 | 2011-02-16 | 细胞基因细胞疗法公司 | 来自人胎盘灌洗液的血管生成细胞 |
| CN101878034B (zh) | 2007-09-28 | 2013-11-20 | 细胞基因细胞疗法公司 | 使用人胎盘灌洗液和人来自胎盘的中间体自然杀伤细胞的肿瘤抑制 |
| EP3345609A1 (en) * | 2007-11-07 | 2018-07-11 | Anthrogenesis Corporation | Use of umbilical cord blood in the treatment of premature birth complications |
| KR20240052847A (ko) * | 2008-08-20 | 2024-04-23 | 셀룰래리티 인코포레이티드 | 개선된 세포 조성물 및 그의 제조 방법 |
| JP5950577B2 (ja) * | 2008-08-20 | 2016-07-13 | アンスロジェネシス コーポレーション | 単離胎盤細胞を使用した脳卒中の治療 |
| US8728805B2 (en) * | 2008-08-22 | 2014-05-20 | Anthrogenesis Corporation | Methods and compositions for treatment of bone defects with placental cell populations |
| NZ592726A (en) * | 2008-11-19 | 2012-12-21 | Anthrogenesis Corp | Amnion derived adherent cells |
| MX2011005230A (es) * | 2008-11-21 | 2011-06-16 | Anthrogenesis Corp | Tratamiento de enfermedades, desordenes o condiciones del pulmon usando celulas de placenta. |
| JP5481177B2 (ja) | 2008-12-09 | 2014-04-23 | 富士フイルム株式会社 | アゾ顔料、アゾ顔料の製造方法、アゾ顔料を含む分散物、及び着色組成物 |
| AR077369A1 (es) | 2009-07-02 | 2011-08-24 | Anthrogenesis Corp | Metodopara producir eritrocitos sin celulas alimentadoras |
| JP5996533B2 (ja) | 2010-07-13 | 2016-09-21 | アントフロゲネシス コーポレーション | ナチュラルキラー細胞を生成させる方法 |
-
2007
- 2007-10-23 EP EP11178000.3A patent/EP2418271A3/en not_active Withdrawn
- 2007-10-23 US US11/877,475 patent/US8562972B2/en not_active Expired - Fee Related
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- 2007-10-23 NZ NZ606814A patent/NZ606814A/en not_active IP Right Cessation
- 2007-10-23 AU AU2007309447A patent/AU2007309447B2/en not_active Ceased
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- 2007-10-23 PL PL07867275T patent/PL2084268T3/pl unknown
- 2007-10-23 EP EP11177991.4A patent/EP2420568A3/en not_active Withdrawn
- 2007-10-23 CA CA2850793A patent/CA2850793A1/en not_active Abandoned
- 2007-10-23 KR KR1020097010688A patent/KR20090076989A/ko not_active Ceased
- 2007-10-23 CN CN200780047519A patent/CN101631852A/zh active Pending
- 2007-10-23 EP EP11177955.9A patent/EP2420567A3/en not_active Withdrawn
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- 2007-10-23 JP JP2009534633A patent/JP2010507392A/ja active Pending
- 2007-10-23 CN CN2012101503259A patent/CN103255098A/zh active Pending
- 2007-10-23 DK DK07867275.5T patent/DK2084268T3/en active
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- 2007-10-23 EP EP18193206.2A patent/EP3483263A1/en not_active Withdrawn
- 2007-10-23 PT PT07867275T patent/PT2084268T/pt unknown
- 2007-10-23 CN CN201410225195.XA patent/CN104099290A/zh active Pending
- 2007-10-23 ZA ZA200902233A patent/ZA200902233B/xx unknown
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2009
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