JP2010500406A5 - - Google Patents
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- Publication number
- JP2010500406A5 JP2010500406A5 JP2009524638A JP2009524638A JP2010500406A5 JP 2010500406 A5 JP2010500406 A5 JP 2010500406A5 JP 2009524638 A JP2009524638 A JP 2009524638A JP 2009524638 A JP2009524638 A JP 2009524638A JP 2010500406 A5 JP2010500406 A5 JP 2010500406A5
- Authority
- JP
- Japan
- Prior art keywords
- crystalline
- formula
- salt
- compound
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 0 COc(cc1)c2nc(C(F)(F)F)ccc2c1-c1nc(C(NCc(ccc(F)c2)c2F)=O)c([C@](C=C*)N)[o]1 Chemical compound COc(cc1)c2nc(C(F)(F)F)ccc2c1-c1nc(C(NCc(ccc(F)c2)c2F)=O)c([C@](C=C*)N)[o]1 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83766106P | 2006-08-14 | 2006-08-14 | |
| PCT/US2007/017848 WO2008021271A1 (en) | 2006-08-14 | 2007-08-10 | Salts of 5 - ( l ( s ) -amino - 2 - hydroxyethyl ) -n- [ ( 2, 4 -difluorophenyl) -methyl] - 2 - [ 8 -methoxy - 2 - (trifluoromethyl) - 5 - quinoline] - 4 - oxazolecarboxamide |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012137788A Division JP2012176989A (ja) | 2006-08-14 | 2012-06-19 | ５−（１（ｓ）−アミノ−２−ヒドロキシエチル）−ｎ−［（２，４−ジフルオロフェニル）−メチル］−２−［８−メトキシ−２−（トリフルオロメチル）−５−キノリン］−４−オキサゾールカルボキサミドの塩 |
| JP2012247215A Division JP2013032394A (ja) | 2006-08-14 | 2012-11-09 | ５−（１（ｓ）−アミノ−２−ヒドロキシエチル）−ｎ−［（２，４−ジフルオロフェニル）−メチル］−２−［８−メトキシ−２−（トリフルオロメチル）−５−キノリン］−４−オキサゾールカルボキサミドの塩 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010500406A JP2010500406A (ja) | 2010-01-07 |
| JP2010500406A5 true JP2010500406A5 (enExample) | 2012-08-09 |
Family
ID=38895795
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009524638A Withdrawn JP2010500406A (ja) | 2006-08-14 | 2007-08-10 | ５−（１（ｓ）−アミノ−２−ヒドロキシエチル）−ｎ−［（２，４−ジフルオロフェニル）−メチル］−２−［８−メトキシ−２−（トリフルオロメチル）−５−キノリン］−４−オキサゾールカルボキサミドの塩 |
| JP2012137788A Withdrawn JP2012176989A (ja) | 2006-08-14 | 2012-06-19 | ５−（１（ｓ）−アミノ−２−ヒドロキシエチル）−ｎ−［（２，４−ジフルオロフェニル）−メチル］−２−［８−メトキシ−２−（トリフルオロメチル）−５−キノリン］−４−オキサゾールカルボキサミドの塩 |
| JP2012247215A Pending JP2013032394A (ja) | 2006-08-14 | 2012-11-09 | ５−（１（ｓ）−アミノ−２−ヒドロキシエチル）−ｎ−［（２，４−ジフルオロフェニル）−メチル］−２−［８−メトキシ−２−（トリフルオロメチル）−５−キノリン］−４−オキサゾールカルボキサミドの塩 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012137788A Withdrawn JP2012176989A (ja) | 2006-08-14 | 2012-06-19 | ５−（１（ｓ）−アミノ−２−ヒドロキシエチル）−ｎ−［（２，４−ジフルオロフェニル）−メチル］−２−［８−メトキシ−２−（トリフルオロメチル）−５−キノリン］−４−オキサゾールカルボキサミドの塩 |
| JP2012247215A Pending JP2013032394A (ja) | 2006-08-14 | 2012-11-09 | ５−（１（ｓ）−アミノ−２−ヒドロキシエチル）−ｎ−［（２，４−ジフルオロフェニル）−メチル］−２−［８−メトキシ−２−（トリフルオロメチル）−５−キノリン］−４−オキサゾールカルボキサミドの塩 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7956189B2 (enExample) |
| EP (1) | EP2069337A1 (enExample) |
| JP (3) | JP2010500406A (enExample) |
| CN (1) | CN101522671A (enExample) |
| AR (1) | AR062373A1 (enExample) |
| CA (1) | CA2660703A1 (enExample) |
| CL (1) | CL2007002366A1 (enExample) |
| MX (1) | MX2009001770A (enExample) |
| PE (1) | PE20080424A1 (enExample) |
| TW (1) | TW200819446A (enExample) |
| WO (1) | WO2008021271A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2336117A1 (en) | 2005-05-26 | 2011-06-22 | Neuron Systems, Inc | Heterocyclic compounds for treating retinal diseases |
| WO2011072141A1 (en) | 2009-12-11 | 2011-06-16 | Neuron Systems, Inc. | Compositions and methods for the treatment of macular degeneration |
| EP2875020B1 (en) * | 2012-07-19 | 2017-09-06 | Boehringer Ingelheim International GmbH | Process for the preparation of a fumaric acid salt of 9-[4-(3-chloro-2-fluoro-phenylamino)-7-methoxy- chinazolin-6-yloxy]-1,4-diaza-spiro[5.5]undecan-5-one |
| CA2898631C (en) | 2013-01-23 | 2023-06-13 | Aldeyra Therapeutics, Inc. | Toxic aldehyde related diseases and treatment |
| CN108135907A (zh) | 2015-08-21 | 2018-06-08 | 奥尔德拉医疗公司 | 氘化化合物和其用途 |
| MX2020003425A (es) | 2017-10-10 | 2020-07-29 | Aldeyra Therapeutics Inc | Tratamiento de trastornos inflamatorios. |
| EP3833660A4 (en) * | 2018-08-06 | 2022-05-11 | Aldeyra Therapeutics, Inc. | POLYMORPHIC COMPOUNDS AND THEIR USES |
| US12098132B2 (en) | 2019-05-02 | 2024-09-24 | Aldeyra Therapeutics, Inc. | Process for preparation of aldehyde scavenger and intermediates |
| CA3137301A1 (en) | 2019-05-02 | 2020-11-05 | Aldeyra Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| WO2021231792A1 (en) | 2020-05-13 | 2021-11-18 | Aldeyra Therapeutics, Inc. | Pharmaceutical formulations and uses thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005247906B2 (en) * | 2004-05-18 | 2011-08-25 | Merck Sharp & Dohme Corp. | Substituted 2-quinolyl-oxazoles useful as PDE4 inhibitors |
-
2007
- 2007-08-10 EP EP07811264A patent/EP2069337A1/en not_active Withdrawn
- 2007-08-10 JP JP2009524638A patent/JP2010500406A/ja not_active Withdrawn
- 2007-08-10 CN CNA2007800382818A patent/CN101522671A/zh active Pending
- 2007-08-10 WO PCT/US2007/017848 patent/WO2008021271A1/en not_active Ceased
- 2007-08-10 MX MX2009001770A patent/MX2009001770A/es active IP Right Grant
- 2007-08-10 US US11/891,351 patent/US7956189B2/en not_active Expired - Fee Related
- 2007-08-10 CA CA002660703A patent/CA2660703A1/en not_active Abandoned
- 2007-08-14 CL CL200702366A patent/CL2007002366A1/es unknown
- 2007-08-14 TW TW096130026A patent/TW200819446A/zh unknown
- 2007-08-14 PE PE2007001088A patent/PE20080424A1/es not_active Application Discontinuation
- 2007-08-14 AR ARP070103601A patent/AR062373A1/es not_active Application Discontinuation
-
2012
- 2012-06-19 JP JP2012137788A patent/JP2012176989A/ja not_active Withdrawn
- 2012-11-09 JP JP2012247215A patent/JP2013032394A/ja active Pending
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