JP2010143932A5 - - Google Patents

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Publication number
JP2010143932A5
JP2010143932A5 JP2010002870A JP2010002870A JP2010143932A5 JP 2010143932 A5 JP2010143932 A5 JP 2010143932A5 JP 2010002870 A JP2010002870 A JP 2010002870A JP 2010002870 A JP2010002870 A JP 2010002870A JP 2010143932 A5 JP2010143932 A5 JP 2010143932A5
Authority
JP
Japan
Prior art keywords
antibody
srage
fragment
peptide
domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010002870A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010143932A (ja
Filing date
Publication date
Priority claimed from US08/948,131 external-priority patent/US6555651B2/en
Application filed filed Critical
Publication of JP2010143932A publication Critical patent/JP2010143932A/ja
Publication of JP2010143932A5 publication Critical patent/JP2010143932A5/ja
Pending legal-status Critical Current

Links

JP2010002870A 1997-10-09 2010-01-08 Ｒａｇｅのリガンド結合部位及びその使用 Pending JP2010143932A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/948,131 US6555651B2 (en) 1997-10-09 1997-10-09 Ligand binding site of rage and uses thereof

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2000515619A Division JP2001519401A (ja) 1997-10-09 1998-10-09 Ｒａｇｅのリガンド結合部位及びその使用

Publications (2)

Publication Number Publication Date
JP2010143932A JP2010143932A (ja) 2010-07-01
JP2010143932A5 true JP2010143932A5 (enExample) 2010-11-18

Family

ID=25487337

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000515619A Withdrawn JP2001519401A (ja) 1997-10-09 1998-10-09 Ｒａｇｅのリガンド結合部位及びその使用
JP2010002870A Pending JP2010143932A (ja) 1997-10-09 2010-01-08 Ｒａｇｅのリガンド結合部位及びその使用

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2000515619A Withdrawn JP2001519401A (ja) 1997-10-09 1998-10-09 Ｒａｇｅのリガンド結合部位及びその使用

Country Status (11)

Country Link
US (1) US6555651B2 (enExample)
EP (2) EP1023080B1 (enExample)
JP (2) JP2001519401A (enExample)
AT (1) ATE476192T1 (enExample)
AU (1) AU9795898A (enExample)
CY (1) CY1110884T1 (enExample)
DE (1) DE69841806D1 (enExample)
DK (1) DK1023080T3 (enExample)
ES (1) ES2351876T3 (enExample)
PT (1) PT1023080E (enExample)
WO (1) WO1999018987A1 (enExample)

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US6555651B2 (en) * 1997-10-09 2003-04-29 The Trustees Of Columbia University In The City Of New York Ligand binding site of rage and uses thereof
US7101838B2 (en) * 1997-08-05 2006-09-05 The Trustees Of Columbia University In The City Of New York Method to prevent accelerated atherosclerosis using (sRAGE) soluble receptor for advanced glycation endproducts
US6465422B1 (en) * 1998-04-17 2002-10-15 The Trustees Of Columbia University In The City Of New York Method for inhibiting tumor invasion or spreading in a subject
AU765719B2 (en) * 1998-10-06 2003-09-25 Trustees Of Columbia University In The City Of New York, The Extracellular novel rage binding protein (EN-RAGE) and uses thereof
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US7199102B2 (en) 2000-08-24 2007-04-03 The Regents Of The University Of California Orally administered peptides synergize statin activity
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US8067371B2 (en) * 2003-05-09 2011-11-29 The Trustees Of Columbia University In The City Of New York RAGE G82S-related methods and compositions for treating inflammatory disorders
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SG161242A1 (en) * 2004-08-03 2010-05-27 Transtech Pharma Inc Rage fusion proteins and methods of use
GEP20105110B (en) * 2004-08-03 2010-11-10 Transtech Pharma Inc Rage fusion proteins and their use
AU2005287004B2 (en) * 2004-09-16 2011-03-17 The Regents Of The University Of California G-type peptides and other agents to ameliorate atherosclerosis and other pathologies
WO2006036922A2 (en) * 2004-09-27 2006-04-06 Centocor, Inc. Srage mimetibody, compositions, methods and uses
KR20070089996A (ko) 2004-12-06 2007-09-04 더 리전트 오브 더 유니버시티 오브 캘리포니아 세동맥의 구조 및 기능의 개선 방법
US9291621B2 (en) * 2005-01-18 2016-03-22 AbbVie Deutschland GmbH & Co. KG AGER-peptides and use thereof
WO2006077101A2 (de) * 2005-01-18 2006-07-27 Abbott Gmbh & Co. Kg Ager-peptide und deren verwendung
BRPI0608401A2 (pt) * 2005-03-17 2010-11-16 Columbia Univ New York polipeptìdeo, composição farmacêutica, ácido nucleico, vetor de expressão, célula, métodos para inibir a ligação entre diáfano e o domìnio citoplasmático de rage, para identificar um agente que inibe a ligação entre o diáfano e o domìnio citoplasmático de rage, e, uso de um agente que inibe a ligação entre diáfano e o domìnio citoplasmático de rage
MX2007013430A (es) * 2005-04-29 2008-03-19 Univ California Peptidos y peptidos mimeticos para tratar patologias caracterizadas por una respuesta inflamatoria.
US20080293639A1 (en) * 2005-04-29 2008-11-27 The Regents Of The University Of California Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response
US20080207499A1 (en) * 2005-06-29 2008-08-28 Gaetano Barile Rage-related methods for treating and preventing diabetic retinopathy
JP5314428B2 (ja) * 2005-12-23 2013-10-16 ジーコデール システムズ アクチボラゲット 測位用パターン
EP1989227A2 (en) * 2006-02-09 2008-11-12 Transtech Pharma, Inc. Rage fusion proteins and methods of use
SG171670A1 (en) * 2006-05-05 2011-06-29 Transtech Pharma Inc Rage fusion proteins, formulations, and methods of use thereof
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KR101595634B1 (ko) * 2007-06-14 2016-02-18 갈락티카 파마슈티칼스, 인크. Ｒａｇｅ 융합 단백질
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WO2011103091A1 (en) 2010-02-18 2011-08-25 Transtech Pharma, Inc. Phenyl-heteroaryl derivatives and methods of use thereof
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US9244074B2 (en) 2011-06-07 2016-01-26 University Of Hawaii Biomarker of asbestos exposure and mesothelioma
WO2012170742A2 (en) 2011-06-07 2012-12-13 University Of Hawaii Treatment and prevention of cancer with hmgb1 antagonists
US9717710B2 (en) 2012-10-05 2017-08-01 Vtv Therapeutics Llc Treatment of mild and moderate Alzheimer's disease
KR101595630B1 (ko) * 2013-01-18 2016-02-18 성균관대학교산학협력단 Rage 단백질-베타아밀로이드 상호작용 억제제, 및 이를 유효성분으로 함유하는 베타아밀로이드 집적 관련 질환의 예방 또는 치료용 약학적 조성물
WO2016018665A1 (en) 2014-07-31 2016-02-04 Uab Research Foundation Apoe mimetic peptides and higher potency to clear plasma cholesterol
WO2019190822A1 (en) 2018-03-28 2019-10-03 Vtv Therapeutics Llc Crystalline forms of [3-(4- {2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine
WO2019190823A1 (en) 2018-03-28 2019-10-03 Vtv Therapeutics Llc Pharmaceutically acceptable salts of [3-(4- {2-butyl-1-[4-(4-chlorophenoxy)-phenyl]-1h-imidazol-4-yl} -phenoxy)-propyl]-diethyl-amine
WO2020076668A1 (en) 2018-10-10 2020-04-16 Vtv Therapeutics Llc Metabolites of [3-(4-{2-butyl-l-[4-(4-chloro-phenoxy)-phenyl]-lh-imidazol-4-yl } -phen ox y)-prop yl] -diethyl-amine

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US6555651B2 (en) * 1997-10-09 2003-04-29 The Trustees Of Columbia University In The City Of New York Ligand binding site of rage and uses thereof

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