JP2010110329A5 - - Google Patents
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- Publication number
- JP2010110329A5 JP2010110329A5 JP2010000787A JP2010000787A JP2010110329A5 JP 2010110329 A5 JP2010110329 A5 JP 2010110329A5 JP 2010000787 A JP2010000787 A JP 2010000787A JP 2010000787 A JP2010000787 A JP 2010000787A JP 2010110329 A5 JP2010110329 A5 JP 2010110329A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- tumor
- cell
- antibody
- sarcoma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39020302P | 2002-06-19 | 2002-06-19 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004516175A Division JP4488512B2 (ja) | 2002-06-19 | 2003-06-19 | 新規のｒａａｇ１０細胞表面標的および当該標的を認識する抗体ファミリー |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011012411A Division JP5372973B2 (ja) | 2002-06-19 | 2011-01-24 | 新規のｒａａｇ１０細胞表面標的および当該標的を認識する抗体ファミリー |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010110329A JP2010110329A (ja) | 2010-05-20 |
| JP2010110329A5 true JP2010110329A5 (cg-RX-API-DMAC7.html) | 2011-03-10 |
Family
ID=30000526
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004516175A Expired - Lifetime JP4488512B2 (ja) | 2002-06-19 | 2003-06-19 | 新規のｒａａｇ１０細胞表面標的および当該標的を認識する抗体ファミリー |
| JP2010000787A Pending JP2010110329A (ja) | 2002-06-19 | 2010-01-05 | 新規のｒａａｇ１０細胞表面標的および当該標的を認識する抗体ファミリー |
| JP2011012411A Expired - Lifetime JP5372973B2 (ja) | 2002-06-19 | 2011-01-24 | 新規のｒａａｇ１０細胞表面標的および当該標的を認識する抗体ファミリー |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004516175A Expired - Lifetime JP4488512B2 (ja) | 2002-06-19 | 2003-06-19 | 新規のｒａａｇ１０細胞表面標的および当該標的を認識する抗体ファミリー |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011012411A Expired - Lifetime JP5372973B2 (ja) | 2002-06-19 | 2011-01-24 | 新規のｒａａｇ１０細胞表面標的および当該標的を認識する抗体ファミリー |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US7527969B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP1565489B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP4488512B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE488530T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2003243749B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2490399C (cg-RX-API-DMAC7.html) |
| DE (1) | DE60335022D1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK1565489T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2356444T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA04012664A (cg-RX-API-DMAC7.html) |
| PT (1) | PT1565489E (cg-RX-API-DMAC7.html) |
| WO (1) | WO2004001381A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2490399C (en) * | 2002-06-19 | 2015-10-06 | Raven Biotechnologies, Inc. | Novel raag10 cell surface target and a family of antibodies recognizing that target |
| ES2381557T3 (es) | 2004-08-03 | 2012-05-29 | Innate Pharma | Métodos terapéuticos y de diagnóstico y composiciones para determinar 4IG-B7-H3 y su receptor homólogo en las células NK |
| JP2009221164A (ja) | 2008-03-17 | 2009-10-01 | Nitto Denko Corp | 肺線維症処置剤 |
| US20120269886A1 (en) | 2004-12-22 | 2012-10-25 | Nitto Denko Corporation | Therapeutic agent for pulmonary fibrosis |
| WO2006083852A2 (en) * | 2005-01-31 | 2006-08-10 | Raven Biotechnologies, Inc. | Luca2 and antibodies that bind thereto |
| JP5328155B2 (ja) | 2005-02-02 | 2013-10-30 | マクロジェニックス ウエスト， インコーポレイテッド | Ａｄａｍ−９モジュレータ |
| US9963510B2 (en) | 2005-04-15 | 2018-05-08 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
| US9572886B2 (en) | 2005-12-22 | 2017-02-21 | Nitto Denko Corporation | Agent for treating myelofibrosis |
| EP2094307A4 (en) * | 2006-11-08 | 2015-08-26 | Macrogenics West Inc | TES7 AND THEREO BINDING ANTIBODIES |
| CA2669260C (en) * | 2006-11-09 | 2019-01-15 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Differential gene expression in physiological and pathological angiogenesis |
| US8309354B2 (en) | 2007-01-22 | 2012-11-13 | Macrogenics West, Inc. | Human cancer stem cells |
| TWI407971B (zh) | 2007-03-30 | 2013-09-11 | Nitto Denko Corp | Cancer cells and tumor-related fibroblasts |
| MX2010010387A (es) | 2008-04-02 | 2010-10-15 | Macrogenics Inc | Anticuerpos especificos para el complejo de bcr y metodos para el uso de los mismos. |
| MX2011006416A (es) | 2008-12-19 | 2011-07-12 | Macrogenics Inc | Diacuerpos covalentes y sus usos. |
| CA2769822C (en) | 2009-08-13 | 2019-02-19 | The Johns Hopkins University | Methods of modulating immune function |
| PH12012501751A1 (en) | 2010-03-04 | 2012-11-12 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| EP2982380B1 (en) | 2010-03-04 | 2021-09-01 | MacroGenics, Inc. | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| EP2601216B1 (en) | 2010-08-02 | 2018-01-03 | MacroGenics, Inc. | Covalent diabodies and uses thereof |
| JP5950428B2 (ja) | 2010-08-05 | 2016-07-13 | 日東電工株式会社 | 線維化組織から正常組織を再生するための組成物 |
| US8642951B2 (en) | 2011-05-04 | 2014-02-04 | Agilent Technologies, Inc. | Device, system, and method for reflecting ions |
| ES2605784T3 (es) | 2011-05-21 | 2017-03-16 | Macrogenics, Inc. | Dominios de enlazamiento a suero desinmunizados y su uso para extender la vida media en suero |
| ES2708932T3 (es) | 2011-06-21 | 2019-04-12 | Nitto Denko Corp | Agente inductor de apoptosis |
| JP6340162B2 (ja) | 2012-12-20 | 2018-06-06 | 日東電工株式会社 | アポトーシス誘導剤 |
| JP6076076B2 (ja) | 2012-12-21 | 2017-02-08 | 日東電工株式会社 | 組織再生促進剤 |
| US9487587B2 (en) | 2013-03-05 | 2016-11-08 | Macrogenics, Inc. | Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof |
| AU2015217278B2 (en) | 2014-02-14 | 2020-03-19 | Macrogenics, Inc. | Improved methods for the treatment of vascularizing cancers |
| US9976142B2 (en) | 2014-04-02 | 2018-05-22 | Nitto Denko Corporation | Targeting molecule and a use thereof |
| RU2676680C2 (ru) | 2014-04-07 | 2019-01-10 | Нитто Денко Корпорейшн | Новые гидротропы на основе полимера для доставки гидрофобного лекарственного средства |
| US10093931B2 (en) | 2014-06-17 | 2018-10-09 | Nitto Denko Corporation | Apoptosis inducer |
| EP3359192A4 (en) | 2015-10-08 | 2019-05-01 | MacroGenics, Inc. | COMBINATION THERAPY FOR CANCER TREATMENT |
| MA44082A (fr) | 2015-12-14 | 2018-10-24 | Macrogenics Inc | Molécules bispécifiques présentant une immunoréactivité par rapport à pd-1 et à ctla-4 et leurs procédés d'utilisation |
| PE20190353A1 (es) | 2016-04-15 | 2019-03-07 | Macrogenics Inc | Moleculas de union b7-h3 novedosas, conjugados anticuerpo-farmaco de los mismos y metodos de uso de los mismos |
| US20200255524A1 (en) | 2016-06-07 | 2020-08-13 | Macrogenics, Inc. | Combination therapy |
| MY199278A (en) * | 2016-06-08 | 2023-10-24 | Abbvie Inc | Anti-b7-h3 antibodies and antibody drug conjugates |
| CA3053803A1 (en) | 2017-02-24 | 2018-08-30 | Macrogenics, Inc. | Bispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof |
| CA3067380A1 (en) * | 2017-06-15 | 2018-12-20 | Development Center For Biotechnology | Antibody-drug conjugates containing anti-globo h antibodies and uses thereof |
| BR112020011810A2 (pt) | 2017-12-12 | 2020-11-17 | Macrogenics, Inc. | molécula de ligação cd16 x antígeno de doença, composição farmacêutica, uso da composição farmacêutica, e método para o tratamento de uma doença |
| EP3752196A4 (en) | 2018-02-15 | 2022-03-23 | MacroGenics, Inc. | CD3-BINDING DOMAIN VARIANTS AND THEIR USE IN COMBINATION THERAPIES FOR THE TREATMENT OF DISEASES |
| KR20220144821A (ko) | 2020-02-21 | 2022-10-27 | 마크로제닉스, 인크. | Cd137 결합 분자 및 그것의 용도 |
| WO2022178218A1 (en) | 2021-02-19 | 2022-08-25 | Mevion Medical Systems, Inc. | Gantry for a particle therapy system |
| EP4373505A1 (en) | 2021-07-19 | 2024-05-29 | Regeneron Pharmaceuticals, Inc. | Combination of checkpoint inhibitors and an oncolytic virus for treating cancer |
| JP2025506696A (ja) | 2022-02-17 | 2025-03-13 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | がんを処置するためのチェックポイント阻害剤と腫瘍溶解性ウイルスの組合せ |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US6054561A (en) * | 1984-02-08 | 2000-04-25 | Chiron Corporation | Antigen-binding sites of antibody molecules specific for cancer antigens |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| US5552391A (en) * | 1990-01-16 | 1996-09-03 | La Jolla Pharmaceutical Company | Chemically-defined non-polymeric valency platform molecules and conjugates thereof |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| DE69233482T2 (de) | 1991-05-17 | 2006-01-12 | Merck & Co., Inc. | Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| GB9115364D0 (en) * | 1991-07-16 | 1991-08-28 | Wellcome Found | Antibody |
| CA2078539C (en) * | 1991-09-18 | 2005-08-02 | Kenya Shitara | Process for producing humanized chimera antibody |
| US5565332A (en) * | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| US5733743A (en) | 1992-03-24 | 1998-03-31 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| US6180377B1 (en) | 1993-06-16 | 2001-01-30 | Celltech Therapeutics Limited | Humanized antibodies |
| US6001359A (en) * | 1993-06-29 | 1999-12-14 | Eli Lilly And Company | Diagnosis of colon carcinoma using monoclonal antibodies to human influx peptide transporter |
| US5532159A (en) | 1994-04-01 | 1996-07-02 | The Ohio State University | Monoclonal antibody to canine placental oncofetal protein for detecting cancer |
| US6265150B1 (en) | 1995-06-07 | 2001-07-24 | Becton Dickinson & Company | Phage antibodies |
| NZ507435A (en) | 1998-03-10 | 2003-12-19 | Genentech Inc | Novel polypeptides and nucleic acids with homology to cornichon |
| WO2000068266A1 (en) | 1999-05-11 | 2000-11-16 | Eli Lilly And Company | Amyloid precursor protein protease and related nucleic acid compounds |
| EP1514933A1 (en) | 1999-07-08 | 2005-03-16 | Research Association for Biotechnology | Secretory protein or membrane protein |
| EP1210428B1 (en) | 1999-08-23 | 2015-03-18 | Dana-Farber Cancer Institute, Inc. | Pd-1, a receptor for b7-4, and uses therefor |
| WO2001014577A1 (en) | 1999-08-24 | 2001-03-01 | Smithkline Beecham Corporation | Molecular cloning of a galanin like 7tm receptor (axor40) |
| US6429303B1 (en) | 1999-09-03 | 2002-08-06 | Curagen Corporation | Nucleic acids encoding members of the human B lymphocyte activation antigen B7 family and methods of using the same |
| JP2003512819A (ja) | 1999-09-03 | 2003-04-08 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | Ｂ７様ポリヌクレオチド、ポリペプチドおよび抗体 |
| US6406840B1 (en) | 1999-12-17 | 2002-06-18 | Biomosaic Systems, Inc. | Cell arrays and the uses thereof |
| US6416999B1 (en) * | 2000-04-07 | 2002-07-09 | Raven Biotechnologies, Inc. | Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof |
| US6987024B1 (en) | 2000-04-10 | 2006-01-17 | Raven Biotechnologies, Inc. | Human ovarian mesothelial cells and methods of isolation and uses thereof |
| US6436704B1 (en) * | 2000-04-10 | 2002-08-20 | Raven Biotechnologies, Inc. | Human pancreatic epithelial progenitor cells and methods of isolation and use thereof |
| US20060154313A1 (en) * | 2000-04-13 | 2006-07-13 | Immunex Corporation | Human B7 polypeptide B7-H3A |
| WO2001089567A1 (en) | 2000-05-22 | 2001-11-29 | Idec Pharmaceuticals Corporation | Identification of unique binding interactions between certain antibodies and the human b7.1 and b7.2 co-stimulatory antigens |
| ATE385504T1 (de) * | 2000-06-06 | 2008-02-15 | Bristol Myers Squibb Co | Nukleinsäuren und polypeptide, die sich auf b7 beziehen und ihre verwendungen zur immunmodulierung |
| US20030031675A1 (en) | 2000-06-06 | 2003-02-13 | Mikesell Glen E. | B7-related nucleic acids and polypeptides useful for immunomodulation |
| EP1892251A3 (en) | 2000-06-06 | 2008-12-31 | Brystol-Myers Squibb Company | B7-related nucleic acids and polypeptides and their uses for immunomodulation |
| US6635750B1 (en) | 2000-07-20 | 2003-10-21 | Millennium Pharmaceuticals, Inc. | B7-H2 nucleic acids, members of the B7 family |
| US6891030B2 (en) * | 2000-07-27 | 2005-05-10 | Mayo Foundation For Medical Education And Research | T-cell immunoregulatory molecule |
| JPWO2002022683A1 (ja) * | 2000-09-12 | 2004-01-22 | 麒麟麦酒株式会社 | 新規樹状細胞膜分子及びその用途 |
| US20030134283A1 (en) * | 2000-10-03 | 2003-07-17 | Peterson David P. | Genes regulated in dendritic cell differentiation |
| WO2002032375A2 (en) | 2000-10-18 | 2002-04-25 | Sloan-Kettering Institute For Cancer Research | Uses of monoclonal antibody 8h9 |
| EP1390497A2 (en) * | 2001-05-25 | 2004-02-25 | Genset | Human cdnas and proteins and uses thereof |
| US20070015144A9 (en) * | 2001-05-25 | 2007-01-18 | Genset, S.A. | Human cDNAs and proteins and uses thereof |
| WO2002097046A2 (en) * | 2001-05-25 | 2002-12-05 | Amgen, Inc. | B7 related protein-2 molecules and uses thereof |
| US6441163B1 (en) | 2001-05-31 | 2002-08-27 | Immunogen, Inc. | Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents |
| US20040236088A1 (en) * | 2001-08-02 | 2004-11-25 | Heuer Josef Georg | Novel polypeptide analogs and fusions and their methods of use |
| AU2003219764B2 (en) | 2002-02-12 | 2008-02-28 | Macrogenics West, Inc. | Human fetal bladder-derived epithelial cells |
| US20040162236A1 (en) * | 2002-04-01 | 2004-08-19 | John Alsobrook | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| CA2490399C (en) * | 2002-06-19 | 2015-10-06 | Raven Biotechnologies, Inc. | Novel raag10 cell surface target and a family of antibodies recognizing that target |
| EP1534331B1 (en) * | 2002-06-21 | 2014-10-29 | Johns Hopkins University School of Medicine | Membrane associated tumor endothelium markers |
-
2003
- 2003-06-19 CA CA2490399A patent/CA2490399C/en not_active Expired - Lifetime
- 2003-06-19 MX MXPA04012664A patent/MXPA04012664A/es active IP Right Grant
- 2003-06-19 PT PT03761281T patent/PT1565489E/pt unknown
- 2003-06-19 EP EP03761281A patent/EP1565489B1/en not_active Expired - Lifetime
- 2003-06-19 EP EP10180500A patent/EP2277917A3/en not_active Withdrawn
- 2003-06-19 AU AU2003243749A patent/AU2003243749B2/en not_active Expired
- 2003-06-19 DE DE60335022T patent/DE60335022D1/de not_active Expired - Lifetime
- 2003-06-19 WO PCT/US2003/019819 patent/WO2004001381A2/en not_active Ceased
- 2003-06-19 AT AT03761281T patent/ATE488530T1/de active
- 2003-06-19 JP JP2004516175A patent/JP4488512B2/ja not_active Expired - Lifetime
- 2003-06-19 DK DK03761281.9T patent/DK1565489T3/da active
- 2003-06-19 ES ES03761281T patent/ES2356444T3/es not_active Expired - Lifetime
- 2003-06-19 US US10/600,802 patent/US7527969B2/en not_active Expired - Lifetime
-
2009
- 2009-03-27 US US12/413,483 patent/US8779098B2/en not_active Expired - Lifetime
-
2010
- 2010-01-05 JP JP2010000787A patent/JP2010110329A/ja active Pending
-
2011
- 2011-01-24 JP JP2011012411A patent/JP5372973B2/ja not_active Expired - Lifetime
-
2014
- 2014-06-03 US US14/294,935 patent/US9574007B2/en not_active Expired - Fee Related