JP2010100624A5 - - Google Patents
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- Publication number
- JP2010100624A5 JP2010100624A5 JP2009259497A JP2009259497A JP2010100624A5 JP 2010100624 A5 JP2010100624 A5 JP 2010100624A5 JP 2009259497 A JP2009259497 A JP 2009259497A JP 2009259497 A JP2009259497 A JP 2009259497A JP 2010100624 A5 JP2010100624 A5 JP 2010100624A5
- Authority
- JP
- Japan
- Prior art keywords
- angptl3
- antibody
- medicament
- medicament according
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33242901P | 2001-11-16 | 2001-11-16 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003545797A Division JP5105696B2 (ja) | 2001-11-16 | 2002-11-13 | アンジオポエチン様タンパク質３Ａｎｇｐｔｌ３含有組成物とその使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010100624A JP2010100624A (ja) | 2010-05-06 |
| JP2010100624A5 true JP2010100624A5 (https=) | 2011-02-03 |
Family
ID=23298191
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003545797A Expired - Fee Related JP5105696B2 (ja) | 2001-11-16 | 2002-11-13 | アンジオポエチン様タンパク質３Ａｎｇｐｔｌ３含有組成物とその使用方法 |
| JP2009259497A Pending JP2010100624A (ja) | 2001-11-16 | 2009-11-13 | アンジオポエチン様タンパク質３Ａｎｇｐｔｌ３含有組成物とその使用方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003545797A Expired - Fee Related JP5105696B2 (ja) | 2001-11-16 | 2002-11-13 | アンジオポエチン様タンパク質３Ａｎｇｐｔｌ３含有組成物とその使用方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US7267819B2 (https=) |
| EP (1) | EP1451578B1 (https=) |
| JP (2) | JP5105696B2 (https=) |
| KR (2) | KR20100029861A (https=) |
| CN (2) | CN1615440A (https=) |
| AU (1) | AU2002348286B2 (https=) |
| CA (1) | CA2464542C (https=) |
| ES (1) | ES2429034T3 (https=) |
| IL (2) | IL161542A0 (https=) |
| MX (1) | MXPA04004609A (https=) |
| NO (1) | NO336021B1 (https=) |
| NZ (1) | NZ532852A (https=) |
| WO (1) | WO2003044172A2 (https=) |
| ZA (1) | ZA200403070B (https=) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050123925A1 (en) | 2002-11-15 | 2005-06-09 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| JP5105696B2 (ja) | 2001-11-16 | 2012-12-26 | ジェネンテック， インコーポレイテッド | アンジオポエチン様タンパク質３Ａｎｇｐｔｌ３含有組成物とその使用方法 |
| AU2004266043B2 (en) * | 2003-08-21 | 2007-09-20 | Duchesnay Inc. | Micronutrient supplement |
| WO2006014678A2 (en) * | 2004-07-20 | 2006-02-09 | Genentech, Inc. | Compositions and methods of using angiopoietin-like 4 protein |
| WO2006014729A2 (en) | 2004-07-20 | 2006-02-09 | Genentech, Inc. | Inhibitors of angiopoietin-like 4 protein, combinations, and their use |
| US8604185B2 (en) | 2004-07-20 | 2013-12-10 | Genentech, Inc. | Inhibitors of angiopoietin-like 4 protein, combinations, and their use |
| US7807645B2 (en) | 2005-09-23 | 2010-10-05 | The Regents Of The University Of California | Method of treating degenerative disorders of the nervous system by administration of fibrinogen fragment |
| PL2121751T3 (pl) * | 2006-12-08 | 2017-07-31 | Lexicon Pharmaceuticals, Inc. | Przeciwciała monoklonalne przeciwko ANGPTL3 |
| WO2009128077A1 (en) * | 2008-04-14 | 2009-10-22 | Hadasit Medical Research Services And Development Ltd. | Stable cell binding chimeric peptides |
| CN101852805B (zh) * | 2009-03-31 | 2015-04-01 | 浙江大学 | Angptl3作为卵巢癌的诊断标记物的用途 |
| AU2010273570B2 (en) * | 2009-07-14 | 2014-07-03 | Novartis Ag | Mesenchymal stem cell differentiation |
| US8653047B2 (en) | 2010-01-08 | 2014-02-18 | Isis Pharmaceuticals, Inc. | Modulation of angiopoietin-like 3 expression |
| AU2015200969A1 (en) * | 2010-01-08 | 2015-03-19 | Ionis Pharmaceuticals, Inc. | Modulation of angiopoietin-like 3 expression |
| JP5838474B2 (ja) * | 2010-02-02 | 2016-01-06 | アリゾナ ボード オブ リージェンツ オン ビハーフ オブ アリゾナ ステート ユニバーシティ | ポリマーの配列を決定するための制御されたトンネルギャップデバイス |
| WO2012103450A2 (en) * | 2011-01-29 | 2012-08-02 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| AR087329A1 (es) | 2011-06-17 | 2014-03-19 | Regeneron Pharma | Anticuerpos humanos contra proteina 3 de tipo angiopoietina humana |
| US9403877B2 (en) | 2012-01-24 | 2016-08-02 | Inter-K Pty Limited | Peptide agents for cancer therapy |
| JO3564B1 (ar) * | 2013-03-08 | 2020-07-05 | Novartis Ag | ببتيدات وتركيبات لعلاج ضرر المفاصل |
| US9301971B2 (en) | 2013-03-08 | 2016-04-05 | Novartis Ag | Peptides and compositions for treatment of joint damage |
| CN104062432B (zh) * | 2013-03-22 | 2016-01-20 | 中山大学 | ang2在制备ECTC血管类型肝癌诊断试剂及治疗药物中的应用 |
| DK2991656T3 (da) | 2013-05-01 | 2020-03-23 | Ionis Pharmaceuticals Inc | Sammensætninger og fremgangsmåder til modulering af apolipoprotein c-iii-ekspression |
| CN111394355A (zh) | 2013-12-24 | 2020-07-10 | Ionis制药公司 | 促血管生成素样3表达的调节 |
| PT3137605T (pt) | 2014-05-01 | 2020-12-18 | Ionis Pharmaceuticals Inc | Composições e métodos para modulação da expressão de angiopoietina de tipo 3 |
| CN105021827B (zh) * | 2015-07-17 | 2016-09-28 | 北京大学第一医院 | 检测血清血管生成素样蛋白2含量的物质在制备检测肝脏炎症和纤维化程度产品中的应用 |
| AU2016349625B2 (en) | 2015-11-06 | 2022-07-07 | Ionis Pharmaceuticals, Inc. | Modulating apolipoprotein (a) expression |
| MX2018009513A (es) * | 2016-02-04 | 2019-01-31 | Regeneron Pharma | Animales no humanos que tienen un gen angptl8 modificado genéticamente. |
| JP7541810B2 (ja) | 2016-03-03 | 2024-08-29 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Ａｎｇｐｔｌ３阻害剤と組み合わせてｐｃｓｋ９阻害剤を投与することにより高脂血症を有する患者を処置するための方法 |
| MX2020001912A (es) * | 2017-09-14 | 2020-03-24 | Arrowhead Pharmaceuticals Inc | Agentes de iarn y composiciones para inhibir la expresion de la angiopoyetina tipo 3 (angptl3) y metodos de uso. |
| AR116566A1 (es) | 2018-10-03 | 2021-05-19 | Novartis Ag | Administración sostenida de polipéptidos similares a la angiopoyetina 3 |
| WO2020099482A2 (en) * | 2018-11-13 | 2020-05-22 | Lipigon Pharmaceuticals Ab | Angptl 3 oligonucleotides influencing the regulation of the fatty acid metabolism |
| TWI747098B (zh) * | 2018-12-21 | 2021-11-21 | 美商美國禮來大藥廠 | 抗angptl3/8複合物抗體及其使用方法 |
| US12559551B2 (en) | 2019-05-24 | 2026-02-24 | Regeneron Pharmaceuticals, Inc. | Stabilized formulations containing anti-ANGPTL3 antibodies |
| EP3993820A4 (en) * | 2019-07-04 | 2023-08-16 | Cadila Healthcare Limited | VACCINE BASED ON ANGPTL3 FOR THE TREATMENT OF LIVER DISEASES |
| CN111122872B (zh) * | 2019-11-20 | 2023-01-20 | 中山大学附属第一医院 | 血管生成素样蛋白7在心力衰竭预后评估中的应用 |
| CN110938144B (zh) * | 2019-11-27 | 2022-07-26 | 复旦大学附属儿科医院 | 一种抗angptl3单克隆抗体及其在制备治疗肾病综合征药物中的用途 |
| US20240141029A1 (en) * | 2021-03-05 | 2024-05-02 | Anji Pharmaceuticals Inc. | Methods and compositions for treating sepsis |
| CN114934021B (zh) * | 2022-04-21 | 2023-08-08 | 复旦大学附属儿科医院 | 一种Angptl3敲除的鼠永生化足细胞系及其应用 |
| CN120254294B (zh) * | 2025-06-05 | 2025-09-09 | 南昌大学第一附属医院 | Angptl3在乙肝相关慢加急性肝衰竭预后中的应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6596850B1 (en) * | 1998-01-30 | 2003-07-22 | Ixsys, Incorporated | Anti-αv3β3 recombinant human antibodies, nucleic acids encoding same |
| WO1998037914A1 (en) * | 1997-02-26 | 1998-09-03 | Toray Industries, Inc. | Remedies for hepatitis |
| US5972338A (en) * | 1997-09-19 | 1999-10-26 | Genentech, Inc. | Tie ligands homologues |
| US6030831A (en) * | 1997-09-19 | 2000-02-29 | Genetech, Inc. | Tie ligand homologues |
| WO1999055869A1 (en) * | 1998-04-27 | 1999-11-04 | Zymogenetics, Inc. | Novel polypeptide growth factors and materials and methods for making them |
| EP1078046A4 (en) * | 1998-05-12 | 2005-05-11 | Human Genome Sciences Inc | 97 HUMAN SECRETED PROTEINS |
| AU4643699A (en) * | 1998-06-24 | 2000-01-10 | Compugen Ltd. | Angiopoietin-like growth factor sequences |
| EP1159419A1 (en) * | 1999-03-08 | 2001-12-05 | Genentech, Inc. | Promotion or inhibition of angiogenesis and cardiovascularization |
| JP5105696B2 (ja) | 2001-11-16 | 2012-12-26 | ジェネンテック， インコーポレイテッド | アンジオポエチン様タンパク質３Ａｎｇｐｔｌ３含有組成物とその使用方法 |
-
2002
- 2002-11-13 JP JP2003545797A patent/JP5105696B2/ja not_active Expired - Fee Related
- 2002-11-13 WO PCT/US2002/036865 patent/WO2003044172A2/en not_active Ceased
- 2002-11-13 MX MXPA04004609A patent/MXPA04004609A/es active IP Right Grant
- 2002-11-13 NZ NZ532852A patent/NZ532852A/en not_active IP Right Cessation
- 2002-11-13 CN CNA028271920A patent/CN1615440A/zh active Pending
- 2002-11-13 EP EP02782310.3A patent/EP1451578B1/en not_active Expired - Lifetime
- 2002-11-13 CN CN2010102426068A patent/CN101905024A/zh active Pending
- 2002-11-13 ES ES02782310T patent/ES2429034T3/es not_active Expired - Lifetime
- 2002-11-13 AU AU2002348286A patent/AU2002348286B2/en not_active Ceased
- 2002-11-13 KR KR1020107004734A patent/KR20100029861A/ko not_active Ceased
- 2002-11-13 CA CA2464542A patent/CA2464542C/en not_active Expired - Fee Related
- 2002-11-13 IL IL16154202A patent/IL161542A0/xx not_active IP Right Cessation
- 2002-11-13 KR KR1020047007410A patent/KR101012904B1/ko not_active Expired - Fee Related
- 2002-11-15 US US10/298,461 patent/US7267819B2/en not_active Expired - Lifetime
-
2004
- 2004-04-22 ZA ZA2004/03070A patent/ZA200403070B/en unknown
- 2004-06-09 NO NO20042410A patent/NO336021B1/no not_active IP Right Cessation
-
2006
- 2006-09-29 US US11/537,567 patent/US20070134250A1/en not_active Abandoned
-
2008
- 2008-05-28 US US12/128,545 patent/US8541376B2/en not_active Expired - Fee Related
-
2009
- 2009-11-13 JP JP2009259497A patent/JP2010100624A/ja active Pending
-
2010
- 2010-02-11 IL IL203894A patent/IL203894A/en not_active IP Right Cessation
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