JP2010017185A5 - - Google Patents
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- Publication number
- JP2010017185A5 JP2010017185A5 JP2009192598A JP2009192598A JP2010017185A5 JP 2010017185 A5 JP2010017185 A5 JP 2010017185A5 JP 2009192598 A JP2009192598 A JP 2009192598A JP 2009192598 A JP2009192598 A JP 2009192598A JP 2010017185 A5 JP2010017185 A5 JP 2010017185A5
- Authority
- JP
- Japan
- Prior art keywords
- flavivirus
- virus
- antigen
- subviral particle
- particle according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000002245 particle Substances 0.000 claims 22
- 241000710831 Flavivirus Species 0.000 claims 19
- 239000000427 antigen Substances 0.000 claims 16
- 102000036639 antigens Human genes 0.000 claims 16
- 108091007433 antigens Proteins 0.000 claims 16
- 241000700605 Viruses Species 0.000 claims 12
- 208000001490 Dengue Diseases 0.000 claims 8
- 206010012310 Dengue fever Diseases 0.000 claims 8
- 208000025729 dengue disease Diseases 0.000 claims 8
- 101710204837 Envelope small membrane protein Proteins 0.000 claims 7
- 101710145006 Lysis protein Proteins 0.000 claims 7
- 238000013518 transcription Methods 0.000 claims 6
- 230000035897 transcription Effects 0.000 claims 6
- 230000002163 immunogen Effects 0.000 claims 5
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 4
- 241000710842 Japanese encephalitis virus Species 0.000 claims 3
- 241000710888 St. Louis encephalitis virus Species 0.000 claims 3
- 101710085938 Matrix protein Proteins 0.000 claims 2
- 101710127721 Membrane protein Proteins 0.000 claims 2
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 2
- 241000710772 Yellow fever virus Species 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 230000003053 immunization Effects 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 238000003786 synthesis reaction Methods 0.000 claims 2
- 229940051021 yellow-fever virus Drugs 0.000 claims 2
- 108091035707 Consensus sequence Proteins 0.000 claims 1
- 241000725619 Dengue virus Species 0.000 claims 1
- 101710172711 Structural protein Proteins 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/826,115 US7227011B2 (en) | 1998-06-04 | 2001-04-04 | Nucleic acid vaccines for prevention of flavivirus infection |
| US09/826,115 | 2001-04-04 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002579516A Division JP4448281B2 (ja) | 2001-04-04 | 2002-04-04 | フラビウイルス感染症の予防のための核酸ワクチン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010017185A JP2010017185A (ja) | 2010-01-28 |
| JP2010017185A5 true JP2010017185A5 (https=) | 2010-10-14 |
| JP5236597B2 JP5236597B2 (ja) | 2013-07-17 |
Family
ID=25245753
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002579516A Expired - Lifetime JP4448281B2 (ja) | 2001-04-04 | 2002-04-04 | フラビウイルス感染症の予防のための核酸ワクチン |
| JP2009192598A Expired - Fee Related JP5236597B2 (ja) | 2001-04-04 | 2009-08-21 | フラビウイルス感染症の予防のための核酸ワクチン |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002579516A Expired - Lifetime JP4448281B2 (ja) | 2001-04-04 | 2002-04-04 | フラビウイルス感染症の予防のための核酸ワクチン |
Country Status (11)
| Country | Link |
|---|---|
| US (6) | US7227011B2 (https=) |
| EP (3) | EP1383931A4 (https=) |
| JP (2) | JP4448281B2 (https=) |
| KR (1) | KR100913984B1 (https=) |
| CN (2) | CN1304575C (https=) |
| BR (1) | BRPI0208301B8 (https=) |
| CA (1) | CA2443323C (https=) |
| MX (1) | MXPA03008838A (https=) |
| NZ (1) | NZ529106A (https=) |
| WO (1) | WO2002081754A1 (https=) |
| ZA (1) | ZA200307580B (https=) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7227011B2 (en) * | 1998-06-04 | 2007-06-05 | United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Nucleic acid vaccines for prevention of flavivirus infection |
| US6977245B2 (en) | 1999-04-12 | 2005-12-20 | The United States Of America As Represented By The Department Of Health And Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| EP1322655B1 (en) | 2000-01-14 | 2007-11-14 | The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services | Oligodeoxynucleotide and its use to induce an immune response |
| US20050031641A1 (en) * | 2001-04-06 | 2005-02-10 | Loosmore Sheena May | Recombinant vaccine against West Nile Virus |
| FR2823222B1 (fr) * | 2001-04-06 | 2004-02-06 | Merial Sas | Vaccin contre le virus de la fievre du nil |
| US20040037848A1 (en) * | 2001-04-06 | 2004-02-26 | Audonnet Jean-Christophe Francis | Recombinant vaccine against West Nile Virus |
| US7740863B2 (en) * | 2001-04-06 | 2010-06-22 | Merial | Recombinant vaccine against West Nile Virus |
| RS53184B (sr) * | 2001-07-27 | 2014-06-30 | Zoetis W Llc | Kompozicija vakcine za primenu u sprečavanju ili ublažavanju encefalitisa zapadnog nila kod ekvida |
| US7666674B2 (en) | 2001-07-27 | 2010-02-23 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of sterically stabilized cationic liposomes to efficiently deliver CPG oligonucleotides in vivo |
| WO2003020884A2 (en) * | 2001-08-14 | 2003-03-13 | The Government Of The United States Of America As Represented By The Secretary Of Health And Human Services | Method for rapid generation of mature dendritic cells |
| US8466116B2 (en) | 2001-12-20 | 2013-06-18 | The Unites States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of CpG oligodeoxynucleotides to induce epithelial cell growth |
| AU2002366710A1 (en) | 2001-12-20 | 2003-07-09 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of | USE OF CpG OLIGODEOXYNUCLEOTIDES TO INDUCE ANGIOGENESIS |
| AU2003263853A1 (en) * | 2002-08-16 | 2004-03-03 | Board Of Regents The University Of Texas System | Compositions and methods related to flavivirus envelope protein domain iii antigens |
| US8263091B2 (en) * | 2002-09-18 | 2012-09-11 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method of treating and preventing infections in immunocompromised subjects with immunostimulatory CpG oligonucleotides |
| EP1601947A2 (en) * | 2002-10-31 | 2005-12-07 | Health Research, Incorporated | Diagnostic test for west nile virus |
| DK1558276T3 (da) * | 2002-11-08 | 2012-10-22 | Univ Tulane | Flavivirus-fusionsinhibitorer |
| CA2432738A1 (en) * | 2003-02-26 | 2004-08-26 | Philippe Despres | New dengue and west nile viruses proteins and genes coding the foregoing, and their use in vaccinal, therapeutic and diagnostic applications |
| WO2004112694A2 (en) | 2003-05-23 | 2004-12-29 | Chiron Corporation | Immunogenic reagents from west nile virus |
| US7060280B2 (en) * | 2003-06-11 | 2006-06-13 | Academia Sinica | Immunization against flavivirus |
| WO2005024427A2 (en) * | 2003-09-09 | 2005-03-17 | Idexx Laboratories, Inc. | Detection of west nile virus infection and vaccination |
| US7074555B2 (en) | 2004-04-28 | 2006-07-11 | Idexx Laboratories, Inc. | Detection of West Nile Virus |
| US20080118528A1 (en) * | 2004-05-04 | 2008-05-22 | Tsanyang Jake Liang | Synthesis and Purification of West Nile Virus Virus-Like Particles |
| JP2008505656A (ja) * | 2004-07-12 | 2008-02-28 | テンジェン バイオメディカル カンパニー | フラビウイルスワクチン |
| ATE521627T1 (de) | 2004-07-27 | 2011-09-15 | Us Gov Health & Human Serv | Identifikation kreuzreaktiver epitope des flavivirus-hüllglykoproteins |
| US7482017B2 (en) * | 2004-09-09 | 2009-01-27 | Research Development Foundation | Flavivirus variants having phenotypic variation and immunogenic compositions thereof |
| JP4993301B2 (ja) * | 2004-10-20 | 2012-08-08 | サノフィ パスツール バイオロジクス リミテッド ライアビリティ カンパニー | 日本脳炎ウイルスおよび西ナイルウイルスに対するワクチン |
| WO2006107655A2 (en) * | 2005-04-01 | 2006-10-12 | Wyeth | Use of wnv dna vaccine in combination with a conventional vaccine to overcome immunogen interference |
| CA2604363C (en) | 2005-04-08 | 2015-06-16 | Wyeth | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| EP1896069B1 (en) * | 2005-06-24 | 2013-03-13 | Intervet International BV | Inactivated chimeric vaccines and related methods of use |
| US7455842B2 (en) * | 2005-12-05 | 2008-11-25 | University Of Kansas | Chimeric West Nile viruses and uses thereof |
| US20070190617A1 (en) * | 2006-02-13 | 2007-08-16 | Chang-Jer Wu | DNA vaccine for Japanese encephalitis virus |
| US20080044808A1 (en) * | 2006-08-15 | 2008-02-21 | Qian-Li Song | West nile virus antigen and assay |
| ES2517615T3 (es) * | 2006-11-09 | 2014-11-03 | The United States Of America As Represented By The Secretary Of The Navy | Inducción de una respuesta inmunitaria frente al virus del dengue usando un enfoque de sensibilización-refuerzo |
| DK2308514T3 (da) | 2007-03-23 | 2013-09-02 | To Bbb Holding B V | Konjugater til målrettet lægemiddeltransport gennem blod-hjerne barrieren |
| JP2008263964A (ja) * | 2007-03-29 | 2008-11-06 | Yamaguchi Univ | コウモリ由来細胞株 |
| EP2003144A1 (en) * | 2007-06-15 | 2008-12-17 | Institut Pasteur | Method for the diagnosis or the screening of an arbovirus infection, reagents useful in said method and their applications |
| WO2009024534A2 (en) * | 2007-08-17 | 2009-02-26 | Intercell Ag | Japanese encephalitis virus (jev) and tick-borne encephalitis virus (tbev) peptides stimulating human t cell responses |
| US8138318B2 (en) * | 2007-09-13 | 2012-03-20 | Abbott Laboratories | Hepatitis B pre-S2 nucleic acid |
| ES2685435T3 (es) * | 2008-01-11 | 2018-10-09 | Inovio Pharmaceuticals, Inc. | Nuevas vacunas frente a múltiples subtipos del virus del dengue |
| WO2009098277A1 (en) * | 2008-02-08 | 2009-08-13 | Intercell Ag | Flaviviridae mutants comprising a deletion in the capsid protein for use as vaccines |
| US20110262472A1 (en) * | 2008-04-22 | 2011-10-27 | Cytos Biotechnology Ag | Vaccine compositions for the treatment of dengue fever and uses thereof |
| CN101333246B (zh) * | 2008-07-30 | 2011-04-13 | 中国农业科学院哈尔滨兽医研究所 | 乙型脑炎病毒e蛋白中和性b细胞抗原表位多肽及其应用 |
| CA2735164C (en) * | 2008-08-29 | 2021-08-31 | Boehringer Ingelheim Vetmedica, Inc. | West nile virus vaccine |
| CN101607983B (zh) * | 2009-07-29 | 2012-06-13 | 中国农业科学院哈尔滨兽医研究所 | 乙型脑炎病毒PrM/M蛋白B细胞抗原表位多肽及应用 |
| CA3150430A1 (en) | 2009-07-31 | 2011-02-03 | Pnuvax Inc. | High yield yellow fever virus strain with increased propagation in cells |
| US20110182976A1 (en) * | 2010-01-28 | 2011-07-28 | National Taiwan Ocean University | Lipoplex-patch based dna vaccine |
| MX2012012681A (es) | 2010-05-21 | 2012-12-17 | Univ Pittsburgh | Secuencias del virus de dengue universales y metodos de uso. |
| AR079970A1 (es) * | 2010-07-23 | 2012-02-29 | Xcellerex Inc | Cepas de alto rendimiento del virus de la fiebre amarilla con una propagacion incrementada en las celulas |
| US20120294889A1 (en) * | 2010-11-12 | 2012-11-22 | Paxvax, Inc. | Chimeric Flavivirus Vaccines |
| EP2772266B1 (en) | 2011-03-14 | 2019-07-31 | Boehringer Ingelheim Animal Health USA Inc. | Equine Rhinitis vaccine |
| US20140286983A1 (en) | 2011-10-20 | 2014-09-25 | The Government of the USA as represented by the Secretaryof the Dept. of Health and Human Services | Dengue virus e-glycoprotein polypeptides containing mutations that eliminate immunodominant cross-reactive epitopes |
| US8920804B2 (en) | 2011-12-22 | 2014-12-30 | Inbios International, Inc. | Methods and materials for the detection of dengue virus infection |
| KR20150036593A (ko) * | 2012-07-24 | 2015-04-07 | 사노피 파스퇴르 | 뎅기열 바이러스 감염 예방용 백신 조성물 |
| TWI852899B (zh) | 2014-09-02 | 2024-08-21 | 法商賽諾菲巴斯德公司 | 疫苗組合物 |
| EP3031923A1 (en) * | 2014-12-11 | 2016-06-15 | Institut Pasteur | Lentiviral vector-based japanese encephalitis immunogenic composition |
| CN104630160B (zh) * | 2015-01-23 | 2018-04-27 | 中国农业科学院哈尔滨兽医研究所 | 表达西尼罗热病毒PrM/E蛋白的重组新城疫LaSota疫苗株 |
| BR112017028212A2 (pt) | 2015-07-03 | 2018-09-11 | Sanofi Pasteur | vacinação concomitante contra dengue e febre amarela |
| EP3324979B1 (en) * | 2015-07-21 | 2022-10-12 | ModernaTX, Inc. | Infectious disease vaccines |
| CA3026807A1 (en) * | 2016-06-13 | 2017-12-21 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Nucleic acids encoding zika virus-like particles and their use in zika virus vaccines and diagnostic assays |
| US20180028643A1 (en) * | 2016-06-21 | 2018-02-01 | Brock Adam Kingstad-Bakke | Zika virus vaccines using virus-like particles |
| WO2018052549A1 (en) | 2016-09-19 | 2018-03-22 | The Usa, As Represented By The Secretary, Dept. Of Health And Human Services | Zika virus vaccines |
| BE1025121B1 (fr) * | 2016-11-17 | 2018-11-05 | Glaxosmithkline Biologicals Sa | Constructions antigeniques du virus zika |
| WO2018152526A1 (en) | 2017-02-20 | 2018-08-23 | The Usa, As Represented By The Secretary, Dept. Of Health And Human Services | Zika virus vaccines |
| SG11202002933TA (en) | 2017-10-05 | 2020-04-29 | Sanofi Pasteur | Compositions for booster vaccination against dengu |
| WO2019162454A1 (en) * | 2018-02-22 | 2019-08-29 | Euroimmun Medizinische Labordiagnostika Ag | Assay for the diagnosis of viral infections |
| EP3530668A1 (en) * | 2018-02-22 | 2019-08-28 | Euroimmun Medizinische Labordiagnostika AG | A novel assay for the diagnosis of viral infections |
| CN113429479B (zh) * | 2018-04-04 | 2023-03-10 | 中国科学院微生物研究所 | 一种高灵敏度的黄热病毒人源单克隆抗体及其应用 |
| CN108904793B (zh) * | 2018-07-29 | 2021-03-30 | 首都医科大学附属北京友谊医院 | 预防流行性乙型脑炎的dna疫苗及其构建方法 |
| WO2020132418A1 (en) * | 2018-12-20 | 2020-06-25 | The Wistar Institute Of Anatomy And Biology | Vaccines against powassan virus, and methods of using same |
| KR20220149907A (ko) * | 2019-12-18 | 2022-11-09 | 진원생명과학 주식회사 | 환자의 예방접종 및 치료를 위한 포와산(powassan) 바이러스 항원 및 관련 조성물, 및 그의 용도 |
| KR102216078B1 (ko) * | 2020-04-22 | 2021-02-16 | 국방과학연구소 | 유전자 백신으로 사용하기 위한 항원 유전자 전달용 발현 벡터 및 이를 포함하는 유전자 백신 |
| US20230272405A1 (en) * | 2020-06-22 | 2023-08-31 | University Of Connecticut | Flavivirus signal peptides, vaccine constructs, and methods therefor |
| WO2024097725A1 (en) * | 2022-11-02 | 2024-05-10 | Takeda Vaccines, Inc. | A method for determining the infectivity of a virus |
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| FR1601438A (https=) | 1968-10-17 | 1970-08-24 | ||
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| WO2002072036A2 (en) | 2001-03-12 | 2002-09-19 | Yale University | Compositions and methods comprising west nile virus polypeptides |
-
2001
- 2001-04-04 US US09/826,115 patent/US7227011B2/en not_active Expired - Lifetime
-
2002
- 2002-04-04 NZ NZ529106A patent/NZ529106A/en not_active IP Right Cessation
- 2002-04-04 EP EP02763960A patent/EP1383931A4/en not_active Withdrawn
- 2002-04-04 CA CA2443323A patent/CA2443323C/en not_active Expired - Lifetime
- 2002-04-04 WO PCT/US2002/010764 patent/WO2002081754A1/en not_active Ceased
- 2002-04-04 MX MXPA03008838A patent/MXPA03008838A/es active IP Right Grant
- 2002-04-04 EP EP10177282.0A patent/EP2332572B1/en not_active Expired - Lifetime
- 2002-04-04 EP EP08004141A patent/EP1935991B1/en not_active Expired - Lifetime
- 2002-04-04 BR BRPI0208301-9 patent/BRPI0208301B8/pt not_active IP Right Cessation
- 2002-04-04 CN CNB02807758XA patent/CN1304575C/zh not_active Expired - Lifetime
- 2002-04-04 KR KR1020037013021A patent/KR100913984B1/ko not_active Expired - Lifetime
- 2002-04-04 US US10/500,796 patent/US7662394B2/en not_active Expired - Lifetime
- 2002-04-04 CN CNA2007100020999A patent/CN101002936A/zh active Pending
- 2002-04-04 JP JP2002579516A patent/JP4448281B2/ja not_active Expired - Lifetime
-
2003
- 2003-09-29 ZA ZA2003/07580A patent/ZA200307580B/en unknown
-
2006
- 2006-06-14 US US11/424,127 patent/US7521177B2/en not_active Expired - Fee Related
- 2006-06-14 US US11/424,138 patent/US7632510B2/en not_active Expired - Lifetime
-
2009
- 2009-07-24 US US12/508,946 patent/US8232379B2/en not_active Expired - Fee Related
- 2009-08-21 JP JP2009192598A patent/JP5236597B2/ja not_active Expired - Fee Related
- 2009-10-15 US US12/580,080 patent/US8221768B2/en not_active Expired - Fee Related
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