JP2013542224A5 - - Google Patents

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Publication number
JP2013542224A5
JP2013542224A5 JP2013536813A JP2013536813A JP2013542224A5 JP 2013542224 A5 JP2013542224 A5 JP 2013542224A5 JP 2013536813 A JP2013536813 A JP 2013536813A JP 2013536813 A JP2013536813 A JP 2013536813A JP 2013542224 A5 JP2013542224 A5 JP 2013542224A5
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JP
Japan
Prior art keywords
protein
composition
den
den1
den2
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JP2013536813A
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English (en)
Japanese (ja)
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JP2013542224A (ja
JP6018575B2 (ja
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Priority claimed from PCT/US2011/058026 external-priority patent/WO2012154202A1/en
Publication of JP2013542224A publication Critical patent/JP2013542224A/ja
Publication of JP2013542224A5 publication Critical patent/JP2013542224A5/ja
Application granted granted Critical
Publication of JP6018575B2 publication Critical patent/JP6018575B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013536813A 2010-10-29 2011-10-27 デングウイルス組換えサブユニットスワクチン Expired - Fee Related JP6018575B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40831010P 2010-10-29 2010-10-29
US61/408,310 2010-10-29
PCT/US2011/058026 WO2012154202A1 (en) 2010-10-29 2011-10-27 Recombinant subunit dengue virus vaccine

Publications (3)

Publication Number Publication Date
JP2013542224A JP2013542224A (ja) 2013-11-21
JP2013542224A5 true JP2013542224A5 (https=) 2014-12-18
JP6018575B2 JP6018575B2 (ja) 2016-11-02

Family

ID=47139466

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013536813A Expired - Fee Related JP6018575B2 (ja) 2010-10-29 2011-10-27 デングウイルス組換えサブユニットスワクチン

Country Status (10)

Country Link
US (2) US9198964B2 (https=)
EP (1) EP2632485A4 (https=)
JP (1) JP6018575B2 (https=)
KR (1) KR20130138789A (https=)
AU (1) AU2011367817B2 (https=)
BR (1) BR112013009649A2 (https=)
MX (1) MX344596B (https=)
MY (1) MY166534A (https=)
SG (3) SG10201801947YA (https=)
WO (1) WO2012154202A1 (https=)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011119628A2 (en) 2010-03-23 2011-09-29 The Regents Of The University Of California Compositions and methods for self-adjuvanting vaccines against microbes and tumors
WO2012019168A2 (en) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
RU2013120302A (ru) 2010-10-01 2014-11-20 Модерна Терапьютикс, Инк. Сконструированные нуклеиновые кислоты и способы их применения
KR20130138789A (ko) 2010-10-29 2013-12-19 머크 샤프 앤드 돔 코포레이션 재조합 서브유닛 뎅기 바이러스 백신
EP2691101A2 (en) 2011-03-31 2014-02-05 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
RU2648950C2 (ru) 2011-10-03 2018-04-02 Модерна Терапьютикс, Инк. Модифицированные нуклеозиды, нуклеотиды и нуклеиновые кислоты и их применение
CN104114572A (zh) 2011-12-16 2014-10-22 现代治疗公司 经修饰的核苷、核苷酸和核酸组合物
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
US9254311B2 (en) 2012-04-02 2016-02-09 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
AU2013243948A1 (en) 2012-04-02 2014-10-30 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins associated with human disease
US8895028B2 (en) * 2012-07-20 2014-11-25 Arbovax, Inc. Methods and compositions for dengue virus 3 (DV3) infectious clone
WO2014081507A1 (en) 2012-11-26 2014-05-30 Moderna Therapeutics, Inc. Terminally modified rna
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
BR112015031226A2 (pt) * 2013-06-21 2017-08-29 Merck Sharp & Dohme Composição de vacina, e, uso da composição de vacina
US10023626B2 (en) 2013-09-30 2018-07-17 Modernatx, Inc. Polynucleotides encoding immune modulating polypeptides
JP2016538829A (ja) 2013-10-03 2016-12-15 モデルナ セラピューティクス インコーポレイテッドModerna Therapeutics,Inc. 低密度リポタンパク質受容体をコードするポリヌクレオチド
GB201413086D0 (en) * 2014-07-23 2014-09-03 Imp Innovations Ltd And Inst Pasteur Methods
EP3236997B1 (en) 2014-12-22 2024-05-29 Merck Sharp & Dohme LLC Dengue virus vaccine compositions and methods of use thereof
US11241491B2 (en) 2017-05-23 2022-02-08 The University Of North Carolina At Chapel Hill Methods and compositions for dengue virus serotype 4 epitopes
WO2019112921A1 (en) 2017-12-07 2019-06-13 Merck Sharp & Dohme Corp. Formulations of dengue virus vaccine compositions
US11576962B2 (en) 2017-12-21 2023-02-14 Green Biomed, Inc. Cross-immunizing antigen vaccine and method for preparation thereof
AU2019225972B2 (en) * 2018-02-22 2024-10-17 Sanofi-Aventis Deutschland Gmbh Variants of porcine trypsin
CN112805030A (zh) * 2018-08-14 2021-05-14 默沙东公司 利用成像细胞计数术的病毒中和测定法
KR102301130B1 (ko) * 2018-12-27 2021-09-15 주식회사 이뮨메드 뎅기출혈열 진단 키트
KR20230147098A (ko) * 2021-01-28 2023-10-20 백신벤트 게엠베하 B 세포 매개 면역 반응을 조절하기 위한 방법 및 수단(method and means for modulating b-cell mediated immune responses)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6136561A (en) 1995-05-24 2000-10-24 Hawaii Biotechnology Group, Inc. Methods of preparing carboxy-terminally truncated recombinant flavivirus envelope glycoproteins employing drosophila melanogaster expression systems
WO1996037221A1 (en) * 1995-05-24 1996-11-28 Hawaii Biotechnology Group, Inc. Subunit vaccine against flavivirus infection
JP2001511459A (ja) * 1997-07-31 2001-08-14 ハワイ バイオテクノロジー グループ, インコーポレイテッド フラビウイルス感染に対抗する組換え二量体エンベロープワクチン
US6416763B1 (en) 1998-08-28 2002-07-09 Hawaii Biotechnology Group, Inc. Recombinant nonstructural protein subunit vaccine against flaviviral infection
US6432411B1 (en) * 1999-07-13 2002-08-13 Hawaii Biotechnology Group Recombinant envelope vaccine against flavivirus infection
CU23245A1 (es) 2001-07-16 2007-10-17 Inst De Medicina Tropical Pedr CADENAS QUIMéRICAS CODIFICANTES PARA PROTEINAS INDUCTORAS DE EFECTOS CONTRA VIRUS. PREPARADOS UTILIZANDO PROTEINAS QUIMéRICAS
US20040213808A1 (en) * 2002-12-11 2004-10-28 Michael Lieberman Recombinant vaccine against flavivirus infection
FR2903605A1 (fr) 2006-07-12 2008-01-18 Sanofi Pasteur Sa Methode d'immunisation contre les quatres serotypes de la dengue
US20110262472A1 (en) 2008-04-22 2011-10-27 Cytos Biotechnology Ag Vaccine compositions for the treatment of dengue fever and uses thereof
KR20130138789A (ko) 2010-10-29 2013-12-19 머크 샤프 앤드 돔 코포레이션 재조합 서브유닛 뎅기 바이러스 백신

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