JP2009543843A - 直接トロンビン阻害剤に関する新規適応 - Google Patents
直接トロンビン阻害剤に関する新規適応 Download PDFInfo
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- JP2009543843A JP2009543843A JP2009519955A JP2009519955A JP2009543843A JP 2009543843 A JP2009543843 A JP 2009543843A JP 2009519955 A JP2009519955 A JP 2009519955A JP 2009519955 A JP2009519955 A JP 2009519955A JP 2009543843 A JP2009543843 A JP 2009543843A
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- dabigatran
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- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| EP06117345 | 2006-07-17 | ||
| EP07102513 | 2007-02-15 | ||
| PCT/EP2007/057256 WO2008009639A2 (en) | 2006-07-17 | 2007-07-13 | New indications for direct thrombin inhibitors |
Publications (2)
| Publication Number | Publication Date |
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| JP2009543843A true JP2009543843A (ja) | 2009-12-10 |
| JP2009543843A5 JP2009543843A5 (https=) | 2010-09-24 |
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| JP2009519955A Pending JP2009543843A (ja) | 2006-07-17 | 2007-07-13 | 直接トロンビン阻害剤に関する新規適応 |
Country Status (7)
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| US (2) | US20080200514A1 (https=) |
| EP (1) | EP2043632A2 (https=) |
| JP (1) | JP2009543843A (https=) |
| AR (1) | AR062057A1 (https=) |
| CA (1) | CA2657269A1 (https=) |
| TW (1) | TW200813012A (https=) |
| WO (1) | WO2008009639A2 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2010143901A (ru) * | 2008-03-28 | 2012-05-10 | Бёрингер Ингельхайм Интернациональ Гмбх (De) | Способ получения композиций дабигатрана для перорального введения |
| JP2011515438A (ja) * | 2008-03-28 | 2011-05-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 酸ペレットの製造方法 |
| BRPI0915942A2 (pt) | 2008-07-14 | 2019-04-09 | Boehringer Ingelheim International Gmbh | método para produção de compostos medicinais contendo dabigatrana |
| CA2734809A1 (en) * | 2008-08-19 | 2010-02-25 | Boehringer Ingelheim International Gmbh | Dabigatran in tumour therapy |
| JP2013510072A (ja) | 2008-11-11 | 2013-03-21 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 従来のワルファリン治療に対して安全性プロフィールが改善されたダビガトランエテキシレートまたはその塩を使用して血栓症を治療または予防するための方法 |
| EP2391893B1 (en) * | 2009-02-02 | 2014-09-03 | Boehringer Ingelheim International GmbH | Lyophilised dabigatran |
| US20120142703A1 (en) * | 2009-05-14 | 2012-06-07 | Boehringer Ingelheim International Gmbh | New combination therapy in treatment of oncological and fibrotic diseases |
| WO2010130758A1 (en) * | 2009-05-14 | 2010-11-18 | Boehringer Ingelheim International Gmbh | New combination therapy in treatment of cancer and fibrotic diseases |
| EP2322163A1 (en) * | 2009-11-03 | 2011-05-18 | Pharnext | New therapeutics approaches for treating alzheimer disease |
| EP2542224B1 (en) * | 2010-03-01 | 2014-08-13 | Ratiopharm GmbH | Dabigatran etexilate-containing oral pharmaceutical composition |
| SI2550966T1 (sl) * | 2011-07-25 | 2017-01-31 | Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co. Kg | Estri amidoksim karboksilne kisline dabigatrana kot predzdravila in njihova uporaba kot zdravila |
| US20130345262A1 (en) | 2012-06-25 | 2013-12-26 | Boehringer Ingelheim International Gmbh | Method for prevention of stroke |
| CN105440017B (zh) * | 2014-08-19 | 2018-03-02 | 天津药物研究院 | 达比加群酯香草酸盐及其制备方法和应用 |
| CN104628733A (zh) * | 2015-03-02 | 2015-05-20 | 中国药科大学 | 四氢苯并[4,5]咪唑并[1,2-a]吡嗪类凝血酶抑制剂 |
| WO2025136810A1 (en) * | 2023-12-19 | 2025-06-26 | The Research Institute At Nationwide Children's Hospital | Anticoagulants for treating nephrotic syndrome |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001509815A (ja) * | 1997-02-18 | 2001-07-24 | ベーリンガー インゲルハイム ファルマ コマンディトゲゼルシャフト | 二置換二環式複素環化合物、これらの調製及び医薬組成物としてのこれらの使用 |
| JP2004503508A (ja) * | 2000-06-10 | 2004-02-05 | アストラゼネカ アクチボラグ | メラガトラン及びＸａ因子阻害剤を含んでなる組合せ製品 |
| WO2004026252A2 (en) * | 2002-09-23 | 2004-04-01 | The Regents Of The University Of Michigan | Glioma treatments |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2258915A1 (en) * | 1996-06-25 | 1997-12-31 | Michael Robert Wiley | Anticoagulant agents |
| US5863292A (en) * | 1996-09-26 | 1999-01-26 | Tosic; Aleksandar | Articulated external orthopedic fixation system and method of use |
| US20030181488A1 (en) * | 2002-03-07 | 2003-09-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof |
| DE10235639A1 (de) * | 2002-08-02 | 2004-02-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Prodrugs von 1-Methyl-2-(4-amidinophenylaminomethyl)-benzimidazol-5-yl-carbonsäure-(N-2-pyridyl-N-2-hydroxycarbonylethyl)-amid, ihre Herstellung und ihre Verwendung als Arzneimittel |
| KR20040076203A (ko) * | 2003-02-24 | 2004-08-31 | 주식회사 엘지생명과학 | 음식물-약물 상호작용을 방지하기 위한 경구 투여용약제학적 조성물 및 방법 |
| AU2004231306A1 (en) * | 2003-04-24 | 2004-11-04 | Boehringer Ingelheim International Gmbh | Use of dipyridamole or mopidamole for treatment and prevention of thrombo-embolic diseases and disorders caused by excessive formation of thrombin and/or by elevated expression of thrombin receptors |
| EP1648232A4 (en) * | 2003-07-17 | 2009-12-30 | Smithkline Beecham Corp | ARGATROBAN TREATMENT METHOD FOR PATIENTS WITH HEPARIN-INDUCED THROMBOCYTOPENIA |
| US20060222640A1 (en) * | 2005-03-29 | 2006-10-05 | Boehringer Ingelheim International Gmbh | New pharmaceutical compositions for treatment of thrombosis |
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2007
- 2007-07-13 AR ARP070103124A patent/AR062057A1/es not_active Application Discontinuation
- 2007-07-13 WO PCT/EP2007/057256 patent/WO2008009639A2/en not_active Ceased
- 2007-07-13 JP JP2009519955A patent/JP2009543843A/ja active Pending
- 2007-07-13 CA CA002657269A patent/CA2657269A1/en not_active Abandoned
- 2007-07-13 EP EP07787524A patent/EP2043632A2/en not_active Withdrawn
- 2007-07-16 TW TW096125876A patent/TW200813012A/zh unknown
- 2007-07-17 US US11/778,748 patent/US20080200514A1/en not_active Abandoned
-
2010
- 2010-03-22 US US12/728,732 patent/US20100173947A1/en not_active Abandoned
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2001509815A (ja) * | 1997-02-18 | 2001-07-24 | ベーリンガー インゲルハイム ファルマ コマンディトゲゼルシャフト | 二置換二環式複素環化合物、これらの調製及び医薬組成物としてのこれらの使用 |
| JP2004503508A (ja) * | 2000-06-10 | 2004-02-05 | アストラゼネカ アクチボラグ | メラガトラン及びＸａ因子阻害剤を含んでなる組合せ製品 |
| WO2004026252A2 (en) * | 2002-09-23 | 2004-04-01 | The Regents Of The University Of Michigan | Glioma treatments |
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Also Published As
| Publication number | Publication date |
|---|---|
| CA2657269A1 (en) | 2008-01-24 |
| US20080200514A1 (en) | 2008-08-21 |
| AR062057A1 (es) | 2008-10-15 |
| EP2043632A2 (en) | 2009-04-08 |
| US20100173947A1 (en) | 2010-07-08 |
| WO2008009639A2 (en) | 2008-01-24 |
| WO2008009639A3 (en) | 2008-06-26 |
| TW200813012A (en) | 2008-03-16 |
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