JP2009543843A5 - - Google Patents

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Publication number
JP2009543843A5
JP2009543843A5 JP2009519955A JP2009519955A JP2009543843A5 JP 2009543843 A5 JP2009543843 A5 JP 2009543843A5 JP 2009519955 A JP2009519955 A JP 2009519955A JP 2009519955 A JP2009519955 A JP 2009519955A JP 2009543843 A5 JP2009543843 A5 JP 2009543843A5
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JP
Japan
Prior art keywords
disease
compound
pharmaceutical composition
group
diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009519955A
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English (en)
Japanese (ja)
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JP2009543843A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/EP2007/057256 external-priority patent/WO2008009639A2/en
Publication of JP2009543843A publication Critical patent/JP2009543843A/ja
Publication of JP2009543843A5 publication Critical patent/JP2009543843A5/ja
Pending legal-status Critical Current

Links

JP2009519955A 2006-07-17 2007-07-13 直接トロンビン阻害剤に関する新規適応 Pending JP2009543843A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06117345 2006-07-17
EP07102513 2007-02-15
PCT/EP2007/057256 WO2008009639A2 (en) 2006-07-17 2007-07-13 New indications for direct thrombin inhibitors

Publications (2)

Publication Number Publication Date
JP2009543843A JP2009543843A (ja) 2009-12-10
JP2009543843A5 true JP2009543843A5 (https=) 2010-09-24

Family

ID=38819790

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009519955A Pending JP2009543843A (ja) 2006-07-17 2007-07-13 直接トロンビン阻害剤に関する新規適応

Country Status (7)

Country Link
US (2) US20080200514A1 (https=)
EP (1) EP2043632A2 (https=)
JP (1) JP2009543843A (https=)
AR (1) AR062057A1 (https=)
CA (1) CA2657269A1 (https=)
TW (1) TW200813012A (https=)
WO (1) WO2008009639A2 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2271317B1 (de) 2008-03-28 2017-04-19 Boehringer Ingelheim International GmbH Verfahren zur herstellung von säurepellets
US20110129538A1 (en) * 2008-03-28 2011-06-02 Boehringer Ingelheim International Gmbh Process for preparing orally administered dabigatran formulations
JP2011527318A (ja) 2008-07-14 2011-10-27 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ダビガトランを含有する医薬組成物の製造方法
US20110306640A1 (en) * 2008-08-19 2011-12-15 Boehringer Ingelheim International Gmbh Dabigatran in tumour therapy
AU2009315729A1 (en) 2008-11-11 2010-05-20 Boehringer Ingelheim International Gmbh Method for treating or preventing thrombosis using dabigatran etexilate or a salt thereof with improved safety profile over conventional warfarin therapy
EP2391893B1 (en) * 2009-02-02 2014-09-03 Boehringer Ingelheim International GmbH Lyophilised dabigatran
JP2012526767A (ja) * 2009-05-14 2012-11-01 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 癌及び線維性疾患の処置における新規な併用療法
US20120142703A1 (en) * 2009-05-14 2012-06-07 Boehringer Ingelheim International Gmbh New combination therapy in treatment of oncological and fibrotic diseases
EP2322163A1 (en) * 2009-11-03 2011-05-18 Pharnext New therapeutics approaches for treating alzheimer disease
SI2542224T1 (sl) * 2010-03-01 2014-10-30 Ratiopharm Gmbh Oralni farmacevtski sestavek, ki vsebuje dabigatran eteksilat
PL2550966T3 (pl) * 2011-07-25 2017-03-31 Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co. Kg Estry kwasu amidooksymokarboksylowego dabigatranu jako proleki i ich zastosowanie jako lek
WO2014001220A1 (en) 2012-06-25 2014-01-03 Boehringer Ingelheim International Gmbh Method for prevention of stroke
CN105440017B (zh) * 2014-08-19 2018-03-02 天津药物研究院 达比加群酯香草酸盐及其制备方法和应用
CN104628733A (zh) * 2015-03-02 2015-05-20 中国药科大学 四氢苯并[4,5]咪唑并[1,2-a]吡嗪类凝血酶抑制剂
WO2025136810A1 (en) * 2023-12-19 2025-06-26 The Research Institute At Nationwide Children's Hospital Anticoagulants for treating nephrotic syndrome

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000514788A (ja) * 1996-06-25 2000-11-07 イーライ・リリー・アンド・カンパニー 抗凝固剤
US5863292A (en) * 1996-09-26 1999-01-26 Tosic; Aleksandar Articulated external orthopedic fixation system and method of use
PE121699A1 (es) * 1997-02-18 1999-12-08 Boehringer Ingelheim Pharma Heterociclos biciclicos disustituidos como inhibidores de la trombina
GB0014136D0 (en) * 2000-06-10 2000-08-02 Astrazeneca Ab Combination therapy
US20030181488A1 (en) * 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof
DE10235639A1 (de) * 2002-08-02 2004-02-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Prodrugs von 1-Methyl-2-(4-amidinophenylaminomethyl)-benzimidazol-5-yl-carbonsäure-(N-2-pyridyl-N-2-hydroxycarbonylethyl)-amid, ihre Herstellung und ihre Verwendung als Arzneimittel
WO2004026252A2 (en) * 2002-09-23 2004-04-01 The Regents Of The University Of Michigan Glioma treatments
KR20040076203A (ko) * 2003-02-24 2004-08-31 주식회사 엘지생명과학 음식물-약물 상호작용을 방지하기 위한 경구 투여용약제학적 조성물 및 방법
JP2006524203A (ja) * 2003-04-24 2006-10-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング トロンビンの過剰形成及び/又はトロンビンレセプターの発現上昇により生じる血栓塞栓性疾病及び疾患の治療及び予防のためのジピリダモール又はモピダモールの使用
EP1648232A4 (en) * 2003-07-17 2009-12-30 Smithkline Beecham Corp ARGATROBAN TREATMENT METHOD FOR PATIENTS WITH HEPARIN-INDUCED THROMBOCYTOPENIA
US20060222640A1 (en) * 2005-03-29 2006-10-05 Boehringer Ingelheim International Gmbh New pharmaceutical compositions for treatment of thrombosis

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