JP2009543825A5 - - Google Patents

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Publication number
JP2009543825A5
JP2009543825A5 JP2009519861A JP2009519861A JP2009543825A5 JP 2009543825 A5 JP2009543825 A5 JP 2009543825A5 JP 2009519861 A JP2009519861 A JP 2009519861A JP 2009519861 A JP2009519861 A JP 2009519861A JP 2009543825 A5 JP2009543825 A5 JP 2009543825A5
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JP
Japan
Prior art keywords
treatment
drug
abuse
anxiety
stress
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009519861A
Other languages
English (en)
Japanese (ja)
Other versions
JP5269784B2 (ja
JP2009543825A (ja
Filing date
Publication date
Priority claimed from DE102006033114A external-priority patent/DE102006033114A1/de
Application filed filed Critical
Publication of JP2009543825A publication Critical patent/JP2009543825A/ja
Publication of JP2009543825A5 publication Critical patent/JP2009543825A5/ja
Application granted granted Critical
Publication of JP5269784B2 publication Critical patent/JP5269784B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2009519861A 2006-07-18 2007-07-17 スピロ環状アザインドール誘導体 Expired - Fee Related JP5269784B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102006033114A DE102006033114A1 (de) 2006-07-18 2006-07-18 Spirocyclische Azaindol-Derivate
DE102006033114.1 2006-07-18
PCT/EP2007/006326 WO2008009416A1 (de) 2006-07-18 2007-07-17 Spirocyclische azaindol-derivate

Publications (3)

Publication Number Publication Date
JP2009543825A JP2009543825A (ja) 2009-12-10
JP2009543825A5 true JP2009543825A5 (https=) 2013-04-11
JP5269784B2 JP5269784B2 (ja) 2013-08-21

Family

ID=38704887

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009519861A Expired - Fee Related JP5269784B2 (ja) 2006-07-18 2007-07-17 スピロ環状アザインドール誘導体

Country Status (21)

Country Link
US (1) US8399503B2 (https=)
EP (1) EP2041142B1 (https=)
JP (1) JP5269784B2 (https=)
KR (1) KR101421034B1 (https=)
CN (1) CN101490055B (https=)
AR (1) AR062079A1 (https=)
AU (1) AU2007276414B2 (https=)
BR (1) BRPI0714650A2 (https=)
CA (1) CA2658379C (https=)
CL (1) CL2007001917A1 (https=)
DE (1) DE102006033114A1 (https=)
ES (1) ES2434114T3 (https=)
IL (1) IL196525A (https=)
MX (1) MX2009000670A (https=)
NO (1) NO342282B1 (https=)
NZ (1) NZ573688A (https=)
PE (1) PE20080277A1 (https=)
PL (1) PL2041142T3 (https=)
RU (1) RU2468028C2 (https=)
WO (1) WO2008009416A1 (https=)
ZA (1) ZA200901128B (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005016460A1 (de) * 2005-04-11 2006-10-19 Grünenthal GmbH Spriocyclische Cyclohexanderivate zur Behandlung von Substanzabhängigkeit
DE102006033114A1 (de) 2006-07-18 2008-01-24 Grünenthal GmbH Spirocyclische Azaindol-Derivate
AU2009228637B2 (en) * 2008-03-27 2013-12-19 Grunenthal Gmbh (Hetero-)aryl cyclohexane derivatives
CA2719735A1 (en) 2008-03-27 2009-10-01 Gruenenthal Gmbh Substituted 4-aminocyclohexane derivatives
PT2260042E (pt) * 2008-03-27 2011-12-06 Gruenenthal Gmbh Derivados de ciclo-hexano espirocíclicos substituídos
WO2009118174A1 (de) 2008-03-27 2009-10-01 Grünenthal GmbH Substituierte cyclohexyldiamine
ATE537143T1 (de) * 2008-03-27 2011-12-15 Gruenenthal Gmbh Spiro(5.5)undecan derivate
JP5599774B2 (ja) 2008-03-27 2014-10-01 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング ヒドロキシメチルシクロヘキシルアミン類
WO2011153359A1 (en) 2010-06-04 2011-12-08 Albany Molecular Research, Inc. Glycine transporter-1 inhibitors, methods of making them, and uses thereof
TWI582092B (zh) 2010-07-28 2017-05-11 歌林達股份有限公司 順式-四氫-螺旋(環己烷-1,1’-吡啶[3,4-b]吲哚)-4-胺-衍生物
EP2649044B1 (en) 2010-12-08 2017-09-20 Grünenthal GmbH Method for synthesising substituted aminocyclohexanone derivatives
JP6557674B2 (ja) * 2014-03-12 2019-08-07 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク 新規クラスのミュー−オピオイド受容体アゴニスト
HUE040133T2 (hu) 2014-07-15 2019-02-28 Gruenenthal Gmbh Szubsztituált azaspiro(4.5)dekán származékok
TW201607923A (zh) 2014-07-15 2016-03-01 歌林達有限公司 被取代之氮螺環(4.5)癸烷衍生物
CA2998868A1 (en) 2015-09-16 2017-03-23 The Trustees Of Columbia University In The City Of New York Carboxylic diarylthiazepineamines as mu-opioid receptor agonists
CN117447384B (zh) * 2023-10-24 2024-12-27 四川大学 一种螺杂环芳基类化合物及其应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4065573A (en) 1976-06-03 1977-12-27 The Upjohn Company 4-Amino-4-phenylcyclohexanone ketal compositions and process of use
EP0738717A1 (en) * 1990-10-09 1996-10-23 Neurogen Corporation Certain substituted pyrimidines as intermediates for production of cycloalkyl and azacycloalkyl pyrrolopyrimidines
WO2000038720A1 (en) * 1998-12-24 2000-07-06 Meiji Seika Kaisha, Ltd. Remedies for pain
GB9918965D0 (en) * 1999-08-11 1999-10-13 Cerebrus Ltd Chemical compounds xxi
HUP0300413A2 (hu) * 2000-04-10 2003-06-28 Pfizer Products Inc. Amidcsoportot viselő benzolgyűrűs csoporttal helyettesített piperidint tartalmazó és rokonszerkezetű vegyületek, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
DE10123163A1 (de) 2001-05-09 2003-01-16 Gruenenthal Gmbh Substituierte Cyclohexan-1,4-diaminderivate
RU2216737C1 (ru) * 2002-03-19 2003-11-20 Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова Способ оценки течения хронического воспалительного процесса в бронхолегочной системе больного муковисцидозом
DE10252667A1 (de) * 2002-11-11 2004-05-27 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
US7872133B2 (en) * 2003-06-23 2011-01-18 Ono Pharmaceutical Co., Ltd. Tricyclic heterocycle compound
DE10360793A1 (de) * 2003-12-23 2005-07-28 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
DE10360792A1 (de) * 2003-12-23 2005-07-28 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
DE102004039382A1 (de) * 2004-08-13 2006-02-23 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
US7659264B2 (en) * 2004-10-07 2010-02-09 Merck Sharp & Dohme Corp. CGRP receptor antagonists
EP1829874B1 (en) * 2004-12-22 2014-02-12 Ono Pharmaceutical Co., Ltd. Tricyclic compound and use thereof
DE102005016460A1 (de) * 2005-04-11 2006-10-19 Grünenthal GmbH Spriocyclische Cyclohexanderivate zur Behandlung von Substanzabhängigkeit
DE102006019597A1 (de) * 2006-04-27 2007-10-31 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
DE102006033114A1 (de) 2006-07-18 2008-01-24 Grünenthal GmbH Spirocyclische Azaindol-Derivate
DE102007009235A1 (de) * 2007-02-22 2008-09-18 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
DE102007009319A1 (de) * 2007-02-22 2008-08-28 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
PT2260042E (pt) * 2008-03-27 2011-12-06 Gruenenthal Gmbh Derivados de ciclo-hexano espirocíclicos substituídos

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