JP2009541354A - 虚血の治療におけるａ２ａアデノシン受容体アゴニストの使用 - Google Patents
虚血の治療におけるａ２ａアデノシン受容体アゴニストの使用 Download PDFInfo
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- JP2009541354A JP2009541354A JP2009516747A JP2009516747A JP2009541354A JP 2009541354 A JP2009541354 A JP 2009541354A JP 2009516747 A JP2009516747 A JP 2009516747A JP 2009516747 A JP2009516747 A JP 2009516747A JP 2009541354 A JP2009541354 A JP 2009541354A
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- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 230000037317 transdermal delivery Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- BSVBQGMMJUBVOD-UHFFFAOYSA-N trisodium borate Chemical compound [Na+].[Na+].[Na+].[O-]B([O-])[O-] BSVBQGMMJUBVOD-UHFFFAOYSA-N 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81575506P | 2006-06-22 | 2006-06-22 | |
| PCT/US2007/071882 WO2008063712A1 (en) | 2006-06-22 | 2007-06-22 | Use of a2a adenosine receptor agonists in the treatment of ischemia |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012228109A Division JP2013010797A (ja) | 2006-06-22 | 2012-10-15 | 虚血の治療におけるａ２ａアデノシン受容体アゴニストの使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009541354A true JP2009541354A (ja) | 2009-11-26 |
| JP2009541354A5 JP2009541354A5 (https=) | 2011-07-14 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009516747A Pending JP2009541354A (ja) | 2006-06-22 | 2007-06-22 | 虚血の治療におけるａ２ａアデノシン受容体アゴニストの使用 |
| JP2012228109A Pending JP2013010797A (ja) | 2006-06-22 | 2012-10-15 | 虚血の治療におけるａ２ａアデノシン受容体アゴニストの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012228109A Pending JP2013010797A (ja) | 2006-06-22 | 2012-10-15 | 虚血の治療におけるａ２ａアデノシン受容体アゴニストの使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20070299089A1 (https=) |
| EP (1) | EP2068850A1 (https=) |
| JP (2) | JP2009541354A (https=) |
| CA (1) | CA2655310A1 (https=) |
| MX (1) | MX2008016254A (https=) |
| WO (1) | WO2008063712A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6403567B1 (en) | 1999-06-22 | 2002-06-11 | Cv Therapeutics, Inc. | N-pyrazole A2A adenosine receptor agonists |
| US6214807B1 (en) * | 1999-06-22 | 2001-04-10 | Cv Therapeutics, Inc. | C-pyrazole 2A A receptor agonists |
| USRE47351E1 (en) | 1999-06-22 | 2019-04-16 | Gilead Sciences, Inc. | 2-(N-pyrazolo)adenosines with application as adenosine A2A receptor agonists |
| CA2671940A1 (en) | 2000-02-23 | 2001-08-30 | Cv Therapeutics, Inc. | Identification of partial agonists of the a2a adenosine receptor |
| NZ537975A (en) * | 2002-07-29 | 2007-08-31 | Cv Therapeutics Inc | Method of producing coronary vasodilation without peripheral vasodilation comprising administering at least 10 mcg of at least one A2A receptor agonist |
| US20050020915A1 (en) * | 2002-07-29 | 2005-01-27 | Cv Therapeutics, Inc. | Myocardial perfusion imaging methods and compositions |
| US8470801B2 (en) | 2002-07-29 | 2013-06-25 | Gilead Sciences, Inc. | Myocardial perfusion imaging methods and compositions |
| KR20070083714A (ko) | 2004-10-20 | 2007-08-24 | 씨브이 쎄러퓨틱스, 인코포레이티드 | Ａ2ａ 아데노신 수용체 작용제의 용도 |
| US7732595B2 (en) | 2006-02-03 | 2010-06-08 | Gilead Palo Alto, Inc. | Process for preparing an A2A-adenosine receptor agonist and its polymorphs |
| US7906518B2 (en) * | 2006-06-27 | 2011-03-15 | Cbt Development Limited | Therapeutic compounds |
| RU2459626C2 (ru) * | 2006-09-01 | 2012-08-27 | Гайлид Сайэнсиз, Инк. | Способы и композиции, повышающие переносимость пациентом методов визуализации миокарда |
| US20090081120A1 (en) * | 2006-09-01 | 2009-03-26 | Cv Therapeutics, Inc. | Methods and Compositions for Increasing Patient Tolerability During Myocardial Imaging Methods |
| US20080170990A1 (en) * | 2006-09-29 | 2008-07-17 | Cv Therapeutics, Inc. | Methods for Myocardial Imaging in Patients Having a History of Pulmonary Disease |
| JP2010515081A (ja) * | 2007-01-03 | 2010-05-06 | ギリアード・パロ・アルト・インコーポレイテッド | 心筋灌流画像化 |
| AU2009296235A1 (en) * | 2008-09-29 | 2010-04-01 | Gilead Sciences, Inc. | Combinations of a rate control agent and an A-2-alpha receptor antagonist for use in multidetector computed tomography methods |
| EP3506947A4 (en) * | 2016-09-01 | 2020-06-03 | Leiutis Pharmaceuticals Pvt. Ltd. | PHARMACEUTICAL FORMULATIONS OF REGADENOSONE |
| CA3023014C (en) * | 2017-11-06 | 2023-09-26 | Stalicla Sa | Pharmaceutical composition for treatment of autism |
| CN112381780B (zh) * | 2020-11-11 | 2021-04-20 | 上海市第六人民医院 | 一种冠脉微循环状况评估装置及方法 |
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| JP2003506461A (ja) * | 1999-06-22 | 2003-02-18 | スィーヴィー セラピューティクス インコーポレイテッド | Ｎ−ピラゾールａ２ａ受容体アゴニスト |
| JP2005511492A (ja) * | 2001-07-20 | 2005-04-28 | エフ．ホフマン−ラ ロシュ アーゲー | ８−メトキシ−（１，２，４）トリアゾロ（１，５−ａ）ピリジン誘導体及びそのアデノシンレセプターリガンドとしての使用 |
| JP2005516006A (ja) * | 2001-12-10 | 2005-06-02 | エフ．ホフマン−ラ ロシュ アーゲー | アデノシン調節薬としての２−アミノベンゾチアゾールの尿素 |
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| RU2459626C2 (ru) * | 2006-09-01 | 2012-08-27 | Гайлид Сайэнсиз, Инк. | Способы и композиции, повышающие переносимость пациентом методов визуализации миокарда |
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| JP2010515081A (ja) * | 2007-01-03 | 2010-05-06 | ギリアード・パロ・アルト・インコーポレイテッド | 心筋灌流画像化 |
-
2007
- 2007-06-22 CA CA002655310A patent/CA2655310A1/en not_active Abandoned
- 2007-06-22 US US11/766,964 patent/US20070299089A1/en not_active Abandoned
- 2007-06-22 MX MX2008016254A patent/MX2008016254A/es not_active Application Discontinuation
- 2007-06-22 WO PCT/US2007/071882 patent/WO2008063712A1/en not_active Ceased
- 2007-06-22 EP EP07870996A patent/EP2068850A1/en not_active Withdrawn
- 2007-06-22 JP JP2009516747A patent/JP2009541354A/ja active Pending
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2012
- 2012-10-15 JP JP2012228109A patent/JP2013010797A/ja active Pending
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| JP2003506461A (ja) * | 1999-06-22 | 2003-02-18 | スィーヴィー セラピューティクス インコーポレイテッド | Ｎ−ピラゾールａ２ａ受容体アゴニスト |
| JP2005511492A (ja) * | 2001-07-20 | 2005-04-28 | エフ．ホフマン−ラ ロシュ アーゲー | ８−メトキシ−（１，２，４）トリアゾロ（１，５−ａ）ピリジン誘導体及びそのアデノシンレセプターリガンドとしての使用 |
| JP2005516006A (ja) * | 2001-12-10 | 2005-06-02 | エフ．ホフマン−ラ ロシュ アーゲー | アデノシン調節薬としての２−アミノベンゾチアゾールの尿素 |
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| JPN6012036943; ＳＡＭＢＵＣＥＴＩ，Ｇ． ｅｔ ａｌ: 'Ｃｏｒｏｎａｒｙ ｍｉｃｒｏｃｉｒｃｕｌａｔｏｒｙ ｖａｓｏｃｏｎｓｔｒｉｃｔｉｏｎ ｉｓ ｈｅｔｅｒｏｇｅｎｅｏｕｓｌｙ ｄｉｓｔｒｉｂｕｔｅｄ ｉｎ ａｃｕｔｅｌｙ ｉｓｃｈｅｍｉｃ ｍｙｏｃａｒ' Ａｍｅｒｉｃａｎ ｊｏｕｒｎａｌ ｏｆ ｐｈｙｓｉｏｌｏｇｙ． Ｈｅａｒｔ ａｎｄ ｃｉｒｃｕｌａｔｏｒｙ ｐｈｙｓｉｏｌｏｇｙ Ｖｏｌ．２８８， Ｎｏ．５, 2005, ｐ．Ｈ２２９８-Ｈ２３０５ * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2655310A1 (en) | 2008-05-29 |
| US20070299089A1 (en) | 2007-12-27 |
| EP2068850A1 (en) | 2009-06-17 |
| MX2008016254A (es) | 2009-01-15 |
| JP2013010797A (ja) | 2013-01-17 |
| WO2008063712A1 (en) | 2008-05-29 |
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Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20121207 |