JP2009540004A5 - - Google Patents
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- Publication number
- JP2009540004A5 JP2009540004A5 JP2009515526A JP2009515526A JP2009540004A5 JP 2009540004 A5 JP2009540004 A5 JP 2009540004A5 JP 2009515526 A JP2009515526 A JP 2009515526A JP 2009515526 A JP2009515526 A JP 2009515526A JP 2009540004 A5 JP2009540004 A5 JP 2009540004A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- alkoxy
- carbamoyl
- alkylamino
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/455,202 US20070293575A1 (en) | 2006-06-15 | 2006-06-15 | Compounds and methods for treatment of cancer-related anemia |
| PCT/US2007/014157 WO2007146438A1 (en) | 2006-06-15 | 2007-06-14 | Hif hydroxylase inhibitors for treatment of anemia of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009540004A JP2009540004A (ja) | 2009-11-19 |
| JP2009540004A5 true JP2009540004A5 (https=) | 2011-03-10 |
Family
ID=38571332
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009515526A Pending JP2009540004A (ja) | 2006-06-15 | 2007-06-14 | 癌の貧血の治療のためのｈｉｆヒドロキシラーゼ阻害剤 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20070293575A1 (https=) |
| EP (1) | EP2035000A1 (https=) |
| JP (1) | JP2009540004A (https=) |
| CN (1) | CN101500569A (https=) |
| AU (1) | AU2007258213A1 (https=) |
| IL (1) | IL195816A0 (https=) |
| WO (1) | WO2007146438A1 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2528232C (en) | 2003-06-06 | 2010-05-25 | Fibrogen, Inc. | Novel nitrogen-containing heteroaryl compounds and their use in increasing endogenous erythropoietin |
| EP2476669A1 (en) * | 2006-01-27 | 2012-07-18 | Fibrogen, Inc. | Cyanoisoquinoline compounds and methods of use thereof |
| CN103497184A (zh) * | 2006-04-04 | 2014-01-08 | 菲布罗根有限公司 | 作为hif调节剂的吡咯并吡啶和噻唑并吡啶化合物 |
| JO2934B1 (en) | 2006-06-23 | 2015-09-15 | سميث كلاين بيتشام كوربوريشن | Prolyl hydroxylase inhibitors |
| TW200845991A (en) | 2007-01-12 | 2008-12-01 | Smithkline Beecham Corp | N-substituted glycine derivatives: hydroxylase inhibitors |
| US8269008B2 (en) * | 2007-12-03 | 2012-09-18 | Fibrogen, Inc. | Oxazolopyridine and isoxazolopyridine derivatives for use in the treatment of HIF-mediated conditions |
| EP2252619B1 (en) | 2008-01-11 | 2013-10-09 | Fibrogen, Inc. | Isothiazole-pyridine derivatives as modulators of hif (hypoxia inducible factor) activity |
| US8324405B2 (en) | 2008-02-05 | 2012-12-04 | Fibrogen, Inc. | Chromene derivatives and use thereof as HIF hydroxylase activity inhibitors |
| EP2334682B1 (en) * | 2008-08-20 | 2017-10-04 | Fibrogen, Inc. | Pyrrolo [ 1, 2 -b] pyridazine derivatives and their use as hif modulators |
| WO2010056767A1 (en) | 2008-11-14 | 2010-05-20 | Fibrogen, Inc. | Thiochromene derivatives as hip hydroxylase inhibitors |
| WO2010059549A1 (en) * | 2008-11-18 | 2010-05-27 | Glaxosmithkline Llc | Prolyl hydroxylase inhibitors |
| WO2011048611A1 (en) | 2009-10-07 | 2011-04-28 | Torrent Pharmaceuticals Limited | Novel fused pyridazine derivatives |
| TWI500623B (zh) | 2009-10-13 | 2015-09-21 | Torrent Pharmaceuticals Ltd | 新穎稠合噻唑及噁唑嘧啶酮 |
| US8541430B2 (en) | 2009-11-27 | 2013-09-24 | Torrent Pharmaceuticals Limited | Fused thiazolo and oxazolo pyrimidinones |
| EP2649182A4 (en) * | 2010-12-10 | 2015-05-06 | Alnylam Pharmaceuticals Inc | Compositions and methods for increasing erythropoietin (epo) production |
| WO2012097329A1 (en) * | 2011-01-13 | 2012-07-19 | Fibrogen, Inc. | Methods for increasing mean corpuscular volume |
| WO2012097331A1 (en) * | 2011-01-13 | 2012-07-19 | Fibrogen, Inc. | Methods for increasing reticulocyte hemoglobin content |
| GB201102659D0 (en) | 2011-02-15 | 2011-03-30 | Isis Innovation | Assay |
| US9206134B2 (en) | 2011-07-22 | 2015-12-08 | Beijing Betta Pharmaceuticals Co. Ltd. | Polymorphic forms of compounds as prolyl hydroxylase inhibitor, and uses thereof |
| GB201113101D0 (en) | 2011-07-28 | 2011-09-14 | Isis Innovation | Assay |
| AU2013229922B2 (en) | 2012-03-09 | 2017-09-28 | Kyntra Bio, Inc. | 4 -hydroxy- isoquinoline compounds as HIF hydroxylase inhibitors |
| US8883823B2 (en) | 2012-07-16 | 2014-11-11 | Fibrogen, Inc. | Crystalline forms of a prolyl hydroxylase inhibitor |
| EP2872487B1 (en) | 2012-07-16 | 2017-04-26 | Fibrogen, Inc. | Process for making isoquinoline compounds |
| KR20210130849A (ko) | 2012-07-16 | 2021-11-01 | 피브로겐, 인크. | 프롤릴 하이드록실라제 억제제 [(4-하이드록시-1-메틸-7-페녹시-아이소퀴놀린-3-카보닐)-아미노]-아세트산의 결정형 |
| CA2899024C (en) | 2013-01-24 | 2022-01-04 | Fibrogen, Inc. | Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid |
| KR20210104173A (ko) | 2013-06-06 | 2021-08-24 | 피브로겐, 인크. | Hif 하이드록실라제 억제자의 약학적 제형 |
| AR099354A1 (es) | 2013-11-15 | 2016-07-20 | Akebia Therapeutics Inc | Formas sólidas de ácido {[5-(3-clorofenil)-3-hidroxipiridin-2-carbonil]amino}acético, composiciones, y sus usos |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102552263A (zh) * | 2001-12-06 | 2012-07-11 | 法布罗根股份有限公司 | 提高内源性红细胞生成素(epo)的方法 |
| US8614204B2 (en) * | 2003-06-06 | 2013-12-24 | Fibrogen, Inc. | Enhanced erythropoiesis and iron metabolism |
| CA2528232C (en) * | 2003-06-06 | 2010-05-25 | Fibrogen, Inc. | Novel nitrogen-containing heteroaryl compounds and their use in increasing endogenous erythropoietin |
| US20060183671A1 (en) * | 2003-07-17 | 2006-08-17 | Anne Angelillo-Scherrer | Treatment of anemia |
| US20060276477A1 (en) * | 2005-06-06 | 2006-12-07 | Fibrogen, Inc. | Treatment method for anemia |
| AU2006259352A1 (en) * | 2005-06-15 | 2006-12-28 | Fibrogen, Inc. | Use of HIF 1alfa modulators for treatment of cancer |
-
2006
- 2006-06-15 US US11/455,202 patent/US20070293575A1/en not_active Abandoned
-
2007
- 2007-06-14 AU AU2007258213A patent/AU2007258213A1/en not_active Abandoned
- 2007-06-14 EP EP07796204A patent/EP2035000A1/en not_active Ceased
- 2007-06-14 CN CNA2007800301280A patent/CN101500569A/zh active Pending
- 2007-06-14 JP JP2009515526A patent/JP2009540004A/ja active Pending
- 2007-06-14 WO PCT/US2007/014157 patent/WO2007146438A1/en not_active Ceased
-
2008
- 2008-12-09 IL IL195816A patent/IL195816A0/en unknown
-
2010
- 2010-08-16 US US12/806,589 patent/US20110015223A1/en not_active Abandoned
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