JP2009539912A5 - - Google Patents
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- Publication number
- JP2009539912A5 JP2009539912A5 JP2009514714A JP2009514714A JP2009539912A5 JP 2009539912 A5 JP2009539912 A5 JP 2009539912A5 JP 2009514714 A JP2009514714 A JP 2009514714A JP 2009514714 A JP2009514714 A JP 2009514714A JP 2009539912 A5 JP2009539912 A5 JP 2009539912A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- hydrogen
- molecule
- preferably selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229910052739 hydrogen Inorganic materials 0.000 claims description 8
- 239000001257 hydrogen Substances 0.000 claims description 8
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 4
- 229910052799 carbon Inorganic materials 0.000 claims description 3
- 229910052736 halogen Inorganic materials 0.000 claims description 3
- 150000002367 halogens Chemical class 0.000 claims description 3
- 150000002431 hydrogen Chemical class 0.000 claims 4
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims 2
- 125000006677 (C1-C3) haloalkoxy group Chemical group 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims 1
- 125000001153 fluoro group Chemical group F* 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 claims 1
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 description 3
- SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 description 3
- 125000003118 aryl group Chemical group 0.000 description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 2
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06090108.9 | 2006-06-13 | ||
| EP06090108A EP1867647A1 (en) | 2006-06-13 | 2006-06-13 | Substituted aminopyrazolopyridines and salts thereof, their preparations and pharmaceutical compositions comprising them. |
| EP07090024 | 2007-02-22 | ||
| EP07090024.6 | 2007-02-22 | ||
| PCT/EP2007/005430 WO2007144202A1 (en) | 2006-06-13 | 2007-06-12 | Substituted aminopyrazolopyridines and salts thereof, their preparations and pharmaceutical compositions comprising them |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009539912A JP2009539912A (ja) | 2009-11-19 |
| JP2009539912A5 true JP2009539912A5 (enExample) | 2013-05-16 |
| JP5475441B2 JP5475441B2 (ja) | 2014-04-16 |
Family
ID=38441698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009514714A Expired - Fee Related JP5475441B2 (ja) | 2006-06-13 | 2007-06-12 | 置換されたアミノピラゾロピリン類及びそれらの塩類、それらの調製及びそれらを含んで成る医薬組成物類 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7825114B2 (enExample) |
| EP (1) | EP2032572B1 (enExample) |
| JP (1) | JP5475441B2 (enExample) |
| AR (1) | AR061345A1 (enExample) |
| CA (1) | CA2654987C (enExample) |
| CL (1) | CL2007001710A1 (enExample) |
| ES (1) | ES2467017T3 (enExample) |
| TW (1) | TW200815437A (enExample) |
| UY (1) | UY30410A1 (enExample) |
| WO (1) | WO2007144202A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20061119A1 (es) * | 2005-01-19 | 2006-11-27 | Aventis Pharma Sa | PIRAZOLO PIRIDINAS SUSTITUIDAS COMO INHIBIDORES DE CINASAS FAK, KDR Y Tie |
| EP2452937A1 (en) * | 2007-04-30 | 2012-05-16 | Abbott Laboratories | Inhibitors of diacylglycerol o-acyltransferase type 1 enzyme |
| EP2307456B1 (en) | 2008-06-27 | 2014-10-15 | Amgen Inc. | Ang-2 inhibition to treat multiple sclerosis |
| JP5689069B2 (ja) | 2008-11-20 | 2015-03-25 | ジェネンテック， インコーポレイテッド | ピラゾロピリジンｐｉ３ｋ阻害剤化合物及び使用方法 |
| EP2464647B1 (en) | 2009-08-11 | 2016-09-21 | Bristol-Myers Squibb Company | Azaindazoles as btk kinase modulators and use thereof |
| CN103214479A (zh) * | 2012-01-18 | 2013-07-24 | 武汉东宇生物医药科技有限公司 | 吡唑类萘脲类酪氨酸激酶抑制剂及其应用 |
| CN103923078A (zh) * | 2013-01-15 | 2014-07-16 | 华东理工大学 | 3,4-二取代(1H-吡唑[3,4-b]吡啶)类化合物及其用途 |
| CN103524421B (zh) * | 2013-09-29 | 2015-04-01 | 镇江蓝德特药业科技有限公司 | 新型萘脲类衍生物及其医疗应用 |
| JOP20190024A1 (ar) | 2016-08-26 | 2019-02-19 | Gilead Sciences Inc | مركبات بيروليزين بها استبدال واستخداماتها |
| CA3072362A1 (en) | 2017-10-06 | 2019-04-11 | Forma Therapeutics, Inc. | Inhibiting ubiquitin specific peptidase 30 |
| JP7050165B2 (ja) | 2018-02-26 | 2022-04-07 | ギリアード サイエンシーズ， インコーポレイテッド | Ｈｂｖ複製阻害剤としての置換ピロリジン化合物 |
| SG11202011299PA (en) | 2018-05-17 | 2020-12-30 | Forma Therapeutics Inc | Fused bicyclic compounds useful as ubiquitin-specific peptidase 30 inhibitors |
| MY209034A (en) | 2018-10-05 | 2025-06-17 | Forma Therapeutics Inc | Fused pyrrolines which act as ubiquitin-specific protease 30 (usp30) inhibitors |
| TW202330519A (zh) * | 2021-09-29 | 2023-08-01 | 香港商德琪研發有限公司 | 作為ｔａｍ抑制劑的吡唑并吡啶化合物 |
| KR20240148322A (ko) * | 2021-12-22 | 2024-10-11 | 아낙시스 파마 피티와이 엘티디 | 이작용성 아릴설폰아미드 화합물 |
| AU2022421952A1 (en) * | 2021-12-22 | 2024-07-04 | Anaxis Pharma Pty Ltd | Arylsulphonamide compounds |
| WO2023155886A1 (en) * | 2022-02-17 | 2023-08-24 | Shanghai Antengene Corporation Limited | Pyrazolopyridine compounds as tam inhibitors |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7491400A (en) * | 1999-09-17 | 2001-04-17 | Abbott Gmbh & Co. Kg | Kinase inhibitors as therapeutic agents |
| JP4810427B2 (ja) | 2003-05-22 | 2011-11-09 | アボット・ラボラトリーズ | インダゾール、ベンズイソオキサゾールおよびベンズイソチアゾールキナーゼ阻害剤 |
| MX2007005120A (es) * | 2004-10-29 | 2007-07-16 | Abbott Lab | Nuevos inhibidores de cinasa. |
-
2007
- 2007-06-11 TW TW096120982A patent/TW200815437A/zh unknown
- 2007-06-12 WO PCT/EP2007/005430 patent/WO2007144202A1/en not_active Ceased
- 2007-06-12 JP JP2009514714A patent/JP5475441B2/ja not_active Expired - Fee Related
- 2007-06-12 ES ES07764751.9T patent/ES2467017T3/es active Active
- 2007-06-12 CL CL2007001710A patent/CL2007001710A1/es unknown
- 2007-06-12 CA CA2654987A patent/CA2654987C/en not_active Expired - Fee Related
- 2007-06-12 US US11/761,621 patent/US7825114B2/en not_active Expired - Fee Related
- 2007-06-12 UY UY30410A patent/UY30410A1/es not_active Application Discontinuation
- 2007-06-12 AR ARP070102551A patent/AR061345A1/es unknown
- 2007-06-12 EP EP07764751.9A patent/EP2032572B1/en not_active Not-in-force
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