JP2009538358A5 - - Google Patents

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Publication number
JP2009538358A5
JP2009538358A5 JP2009513231A JP2009513231A JP2009538358A5 JP 2009538358 A5 JP2009538358 A5 JP 2009538358A5 JP 2009513231 A JP2009513231 A JP 2009513231A JP 2009513231 A JP2009513231 A JP 2009513231A JP 2009538358 A5 JP2009538358 A5 JP 2009538358A5
Authority
JP
Japan
Prior art keywords
oxazol
piperidin
methanone
benzyl
ylmethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2009513231A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009538358A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2007/012631 external-priority patent/WO2007140005A2/en
Publication of JP2009538358A publication Critical patent/JP2009538358A/ja
Publication of JP2009538358A5 publication Critical patent/JP2009538358A5/ja
Withdrawn legal-status Critical Current

Links

JP2009513231A 2006-05-26 2007-05-25 脂肪酸アミド加水分解酵素のオキサゾリルピペリジン・モジュレーター Withdrawn JP2009538358A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80872306P 2006-05-26 2006-05-26
PCT/US2007/012631 WO2007140005A2 (en) 2006-05-26 2007-05-25 Oxazolyl piperidine modulators of fatty acid amide hydrolase

Publications (2)

Publication Number Publication Date
JP2009538358A JP2009538358A (ja) 2009-11-05
JP2009538358A5 true JP2009538358A5 (https=) 2010-07-01

Family

ID=38779275

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009513231A Withdrawn JP2009538358A (ja) 2006-05-26 2007-05-25 脂肪酸アミド加水分解酵素のオキサゾリルピペリジン・モジュレーター

Country Status (4)

Country Link
US (1) US20100292266A1 (https=)
EP (1) EP2023728A4 (https=)
JP (1) JP2009538358A (https=)
WO (1) WO2007140005A2 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
EP2254415B1 (en) 2008-02-19 2013-01-23 Janssen Pharmaceutica, N.V. Aryl-hydroxyethylamino-pyrimidines and triazines as modulators of fatty acid amide hydrolase
AU2009257795A1 (en) * 2008-06-11 2009-12-17 Merck Sharp & Dohme Corp. Pyrazole derivatives useful as inhibitors of FAAH
US8906914B2 (en) 2009-08-18 2014-12-09 Janssen Pharmaceutica Nv Ethylene diamine modulators of fatty acid hydrolase
WO2011085216A2 (en) 2010-01-08 2011-07-14 Ironwood Pharmaceuticals, Inc. Use of faah inhibitors for treating parkinson's disease and restless legs syndrome
US20130224151A1 (en) 2010-03-31 2013-08-29 United States Of America Use of FAAH Inhibitors for Treating Abdominal, Visceral and Pelvic Pain
BR112012023974A2 (pt) * 2010-04-08 2017-09-26 Merck Sharp & Dohme composto, composição farmacêutica, método de tratar uma doença mediada com faah, e, uso de um composto.
EP2670245B1 (en) * 2011-02-04 2015-09-09 The Scripps Research Institute Alpha-ketoheterocycles and methods of making and using
EP2766349B1 (de) 2011-03-08 2016-06-01 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8828994B2 (en) 2011-03-08 2014-09-09 Sanofi Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2683699B1 (de) 2011-03-08 2015-06-24 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120056A1 (de) 2011-03-08 2012-09-13 Sanofi Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683704B1 (de) 2011-03-08 2014-12-17 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
JP2017529401A (ja) * 2014-09-26 2017-10-05 チャーンジョウ インシュヨン ファーマシューティカル カンパニー，リミティド Ｎｓ４ｂ阻害剤としてのベンゾフラン類似体
CN108084130B (zh) * 2017-12-15 2019-09-10 东南大学 一种降糖药达格列净的制备方法
WO2020179859A1 (ja) 2019-03-06 2020-09-10 第一三共株式会社 ピロロピラゾール誘導体
CN110804048A (zh) * 2019-11-08 2020-02-18 暨南大学 恶唑酮类化合物及其应用、faah的正电子药物
EP4329881A4 (en) * 2021-04-30 2025-06-11 Vanqua Bio, Inc. Small molecule modulators of glucocerebrosidase activity and uses thereof
CN115850241B (zh) * 2021-09-24 2025-01-14 中国药科大学 一种含α-酮骨架的取代杂环类化合物及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856537A (en) * 1996-06-26 1999-01-05 The Scripps Research Institute Inhibitors of oleamide hydrolase
US6462054B1 (en) * 2000-03-27 2002-10-08 The Scripps Research Institute Inhibitors of fatty acid amide hydrolase
EA010267B1 (ru) * 2002-10-07 2008-06-30 Те Риджентс Оф Те Юниверсити Оф Калифорния Модуляция тревоги через блокаду гидролиза анандамида
AU2004289303A1 (en) * 2003-11-10 2005-05-26 Synta Pharmaceuticals, Corp. Fused heterocyclic compounds
WO2006044617A1 (en) * 2004-10-15 2006-04-27 The Scripps Research Institute Oxadiazole ketone inhibitors of fatty acid amide hydrolase
NZ590148A (en) * 2004-12-30 2012-04-27 Janssen Pharmaceutica Nv Piperazinyl and piperidinyl ureas as modulators of fatty acid amide hydrolase

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