JP2009538358A5 - - Google Patents

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Publication number
JP2009538358A5
JP2009538358A5 JP2009513231A JP2009513231A JP2009538358A5 JP 2009538358 A5 JP2009538358 A5 JP 2009538358A5 JP 2009513231 A JP2009513231 A JP 2009513231A JP 2009513231 A JP2009513231 A JP 2009513231A JP 2009538358 A5 JP2009538358 A5 JP 2009538358A5
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JP
Japan
Prior art keywords
oxazol
piperidin
methanone
benzyl
ylmethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2009513231A
Other languages
English (en)
Japanese (ja)
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JP2009538358A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2007/012631 external-priority patent/WO2007140005A2/en
Publication of JP2009538358A publication Critical patent/JP2009538358A/ja
Publication of JP2009538358A5 publication Critical patent/JP2009538358A5/ja
Withdrawn legal-status Critical Current

Links

JP2009513231A 2006-05-26 2007-05-25 脂肪酸アミド加水分解酵素のオキサゾリルピペリジン・モジュレーター Withdrawn JP2009538358A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80872306P 2006-05-26 2006-05-26
PCT/US2007/012631 WO2007140005A2 (en) 2006-05-26 2007-05-25 Oxazolyl piperidine modulators of fatty acid amide hydrolase

Publications (2)

Publication Number Publication Date
JP2009538358A JP2009538358A (ja) 2009-11-05
JP2009538358A5 true JP2009538358A5 (https=) 2010-07-01

Family

ID=38779275

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009513231A Withdrawn JP2009538358A (ja) 2006-05-26 2007-05-25 脂肪酸アミド加水分解酵素のオキサゾリルピペリジン・モジュレーター

Country Status (4)

Country Link
US (1) US20100292266A1 (https=)
EP (1) EP2023728A4 (https=)
JP (1) JP2009538358A (https=)
WO (1) WO2007140005A2 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
CA2714743C (en) 2008-02-19 2017-01-17 Janssen Pharmaceutica N.V. Aryl-hydroxyethylamino-pyrimidines and triazines as modulators of fatty acid amide hydrolase
EP2299824B1 (en) * 2008-06-11 2013-06-19 Merck Sharp & Dohme Corp. Pyrazole derivatives useful as inhibitors of faah
US8906914B2 (en) 2009-08-18 2014-12-09 Janssen Pharmaceutica Nv Ethylene diamine modulators of fatty acid hydrolase
WO2011085216A2 (en) 2010-01-08 2011-07-14 Ironwood Pharmaceuticals, Inc. Use of faah inhibitors for treating parkinson's disease and restless legs syndrome
WO2011123719A2 (en) 2010-03-31 2011-10-06 Ironwood Pharmaceuticals, Inc. Use of faah inhibitors for treating abdominal, visceral and pelvic pain
JP2013523814A (ja) * 2010-04-08 2013-06-17 メルク・シャープ・エンド・ドーム・コーポレイション Ｆａａｈの調節薬として有用なオキサゾール誘導体
EP2670245B1 (en) * 2011-02-04 2015-09-09 The Scripps Research Institute Alpha-ketoheterocycles and methods of making and using
US8828995B2 (en) 2011-03-08 2014-09-09 Sanofi Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
EP2683705B1 (de) 2011-03-08 2015-04-22 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8871758B2 (en) 2011-03-08 2014-10-28 Sanofi Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
WO2012120052A1 (de) 2011-03-08 2012-09-13 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2683699B1 (de) 2011-03-08 2015-06-24 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2016045587A1 (zh) * 2014-09-26 2016-03-31 常州寅盛药业有限公司 作为ns4b抑制剂的苯并呋喃类似物
CN108084130B (zh) * 2017-12-15 2019-09-10 东南大学 一种降糖药达格列净的制备方法
WO2020179859A1 (ja) 2019-03-06 2020-09-10 第一三共株式会社 ピロロピラゾール誘導体
CN110804048A (zh) * 2019-11-08 2020-02-18 暨南大学 恶唑酮类化合物及其应用、faah的正电子药物
EP4329881A4 (en) * 2021-04-30 2025-06-11 Vanqua Bio, Inc. Small molecule modulators of glucocerebrosidase activity and uses thereof
CN115850241B (zh) * 2021-09-24 2025-01-14 中国药科大学 一种含α-酮骨架的取代杂环类化合物及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856537A (en) * 1996-06-26 1999-01-05 The Scripps Research Institute Inhibitors of oleamide hydrolase
US6462054B1 (en) * 2000-03-27 2002-10-08 The Scripps Research Institute Inhibitors of fatty acid amide hydrolase
EP1558591B1 (en) * 2002-10-07 2014-05-07 The Regents of The University of California Modulation of anxiety through blockade of anandamide hydrolysis
AU2004289303A1 (en) * 2003-11-10 2005-05-26 Synta Pharmaceuticals, Corp. Fused heterocyclic compounds
US7351724B2 (en) * 2004-10-15 2008-04-01 The Scripps Research Institute Oxadiazole ketone inhibitors of fatty acid amide hydrolase
AR055831A1 (es) * 2004-12-30 2007-09-12 Janssen Pharmaceutica Nv Pepirazinilureas y piperidinilureas como moduladores de hidrolasa de amida de acidos grasos

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