JP2009538276A - 嚢胞性線維症の改良型治療 - Google Patents
嚢胞性線維症の改良型治療 Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Molecular Biology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Epoxy Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
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| US79408806P | 2006-04-24 | 2006-04-24 | |
| PCT/NL2007/050177 WO2007123403A1 (en) | 2006-04-24 | 2007-04-24 | Improved treatment of cystic fibrosis |
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| JP2009538276A true JP2009538276A (ja) | 2009-11-05 |
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| GB0712494D0 (en) | 2007-06-27 | 2007-08-08 | Isis Innovation | Substrate reduction therapy |
| EP2398321B1 (en) | 2009-02-23 | 2015-11-25 | United Therapeutics Corporation | Iminosugars and methods of treating viral diseases |
| CA2753194A1 (en) * | 2009-02-24 | 2010-09-02 | United Therapeutics Corporation | Iminosugars and methods of treating arenaviral infections |
| CN102639133B (zh) | 2009-06-12 | 2015-03-11 | 联合治疗公司 | 亚氨基糖和治疗布尼亚病毒性疾病以及披膜病毒性疾病的方法 |
| JP5752689B2 (ja) * | 2009-09-04 | 2015-07-22 | ユナイテッド セラピューティクス コーポレイション | フィロウイルス疾患を治療するイミノ糖および方法 |
| CA2772807A1 (en) * | 2009-09-04 | 2011-03-10 | The Chancellor, Masters And Scholars Of The University Of Oxford | Methods of treating poxviral infections |
| US20110065752A1 (en) * | 2009-09-04 | 2011-03-17 | United Therapeutics Corporation | Methods of treating orthomyxoviral infections |
| GB201000499D0 (en) | 2010-01-13 | 2010-03-03 | Fleet George W J | Treatment of cystic fibrosis |
| WO2011095772A2 (en) | 2010-02-04 | 2011-08-11 | Summit Corporation Plc | Novel iminosugar therapeutics |
| GB201006434D0 (en) | 2010-04-19 | 2010-06-02 | Summit Corp Plc | Novel iminosugar combinations |
| ES2791760T3 (es) | 2011-09-07 | 2020-11-05 | Sinai School Medicine | Ceramidasa y diferenciación celular |
| HUE051020T2 (hu) * | 2012-06-01 | 2021-01-28 | Icahn School Med Mount Sinai | A ceramid szintjei a fertõzések kezelésében és megelõzésében |
| US20150346185A1 (en) * | 2012-12-05 | 2015-12-03 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Diagnosis of cystic fibrosis |
| JP6832158B2 (ja) | 2013-03-14 | 2021-02-24 | アイカーン スクール オブ メディシン アット マウント サイナイ | 治療用酸性セラミダーゼ組成物ならびにそれを作製および使用する方法 |
| WO2017178499A1 (en) | 2016-04-11 | 2017-10-19 | Spedding Research Solutions | Inhibitors of glucosylceramide degradation in the treatment of diseases of the motor units |
| MA48944A (fr) | 2017-06-01 | 2020-04-08 | Idorsia Pharmaceuticals Ltd | Forme cristalline de n-butyldéoxygalactonojirimycine |
| CA3211755A1 (en) * | 2021-03-12 | 2022-09-15 | Barbara MERTINS | Systems and methods for protein expression |
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| WO2005040118A1 (en) * | 2003-10-29 | 2005-05-06 | Macrozyme B.V. | Deoxynojirimycin analogues and their uses as glucosylceramidase inhibitors |
| WO2005046672A2 (fr) * | 2003-11-07 | 2005-05-26 | Centre National De La Recherche Scientifique | Utilisation d’inhibiteurs de glucosidase pour une therapie de la mucoviscidose |
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| WO1998002161A1 (en) | 1996-07-15 | 1998-01-22 | Universiteit Van Amsterdam | Deoxynojirimycin derivatives and their uses as glucosylceramidase inhibitors |
| WO2001002586A1 (en) | 1999-06-29 | 2001-01-11 | Mcgill University | Human alpha 1,2-mannosidase |
| US20090111812A1 (en) * | 2004-06-14 | 2009-04-30 | Musc Foundation For Research Development | Methods for treating inflammatory disorders |
| US20100004156A1 (en) | 2005-07-27 | 2010-01-07 | Shalesh Kaushal | Small Compounds That Correct Protein Misfolding and Uses Thereof |
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- 2007-04-24 EP EP07747401A patent/EP2010551B1/en not_active Not-in-force
- 2007-04-24 US US12/298,506 patent/US8410081B2/en not_active Expired - Fee Related
- 2007-04-24 WO PCT/NL2007/050177 patent/WO2007123403A1/en not_active Ceased
- 2007-04-24 JP JP2009507606A patent/JP2009538276A/ja not_active Ceased
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- 2007-04-24 AU AU2007241622A patent/AU2007241622A1/en not_active Abandoned
- 2007-04-24 CN CN2007800237886A patent/CN101479288B/zh not_active Expired - Fee Related
- 2007-04-24 BR BRPI0710883-4A patent/BRPI0710883A2/pt not_active IP Right Cessation
- 2007-04-24 CA CA002650311A patent/CA2650311A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005040118A1 (en) * | 2003-10-29 | 2005-05-06 | Macrozyme B.V. | Deoxynojirimycin analogues and their uses as glucosylceramidase inhibitors |
| WO2005046672A2 (fr) * | 2003-11-07 | 2005-05-26 | Centre National De La Recherche Scientifique | Utilisation d’inhibiteurs de glucosidase pour une therapie de la mucoviscidose |
Non-Patent Citations (1)
| Title |
|---|
| JPN6012044955; ＦＥＢＳ Ｌｅｔｔｅｒｓ Ｖｏｌ．５８０, 200603, ｐｐ．２０８１-６ * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101479288B (zh) | 2012-06-27 |
| AU2007241622A8 (en) | 2008-12-04 |
| CA2650311A1 (en) | 2007-11-01 |
| US20090186862A1 (en) | 2009-07-23 |
| AU2007241622A1 (en) | 2007-11-01 |
| US8410081B2 (en) | 2013-04-02 |
| EP2010551B1 (en) | 2010-09-01 |
| WO2007123403A1 (en) | 2007-11-01 |
| CN101479288A (zh) | 2009-07-08 |
| BRPI0710883A2 (pt) | 2011-08-09 |
| EP2010551A1 (en) | 2009-01-07 |
| ATE479696T1 (de) | 2010-09-15 |
| DE602007008870D1 (de) | 2010-10-14 |
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