BRPI0710883A2 - uso de um inibidor de gba2, e, composto - Google Patents
uso de um inibidor de gba2, e, composto Download PDFInfo
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- BRPI0710883A2 BRPI0710883A2 BRPI0710883-4A BRPI0710883A BRPI0710883A2 BR PI0710883 A2 BRPI0710883 A2 BR PI0710883A2 BR PI0710883 A BRPI0710883 A BR PI0710883A BR PI0710883 A2 BRPI0710883 A2 BR PI0710883A2
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- BR
- Brazil
- Prior art keywords
- deoxinojirimycin
- group
- carbon atoms
- gba2
- use according
- Prior art date
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- 125000006413 ring segment Chemical group 0.000 description 1
- 201000005404 rubella Diseases 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 description 1
- 235000011888 snacks Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 238000000539 two dimensional gel electrophoresis Methods 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
- 238000001262 western blot Methods 0.000 description 1
- 150000008495 β-glucosides Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Epoxy Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79408806P | 2006-04-24 | 2006-04-24 | |
| US60/794088 | 2006-04-24 | ||
| PCT/NL2007/050177 WO2007123403A1 (en) | 2006-04-24 | 2007-04-24 | Improved treatment of cystic fibrosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0710883A2 true BRPI0710883A2 (pt) | 2011-08-09 |
Family
ID=38283020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0710883-4A BRPI0710883A2 (pt) | 2006-04-24 | 2007-04-24 | uso de um inibidor de gba2, e, composto |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8410081B2 (enExample) |
| EP (1) | EP2010551B1 (enExample) |
| JP (1) | JP2009538276A (enExample) |
| CN (1) | CN101479288B (enExample) |
| AT (1) | ATE479696T1 (enExample) |
| AU (1) | AU2007241622A1 (enExample) |
| BR (1) | BRPI0710883A2 (enExample) |
| CA (1) | CA2650311A1 (enExample) |
| DE (1) | DE602007008870D1 (enExample) |
| WO (1) | WO2007123403A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0712494D0 (en) | 2007-06-27 | 2007-08-08 | Isis Innovation | Substrate reduction therapy |
| JP5600329B2 (ja) | 2009-02-23 | 2014-10-01 | ユナイテッド セラピューティクス コーポレーション | イミノ糖およびウイルス性疾患を治療する方法 |
| KR101787434B1 (ko) * | 2009-02-24 | 2017-11-15 | 유나이티드 세러퓨틱스 코오포레이션 | 이미노슈가 및 아레나바이러스성 감염을 치료하는 방법 |
| JP5634510B2 (ja) | 2009-06-12 | 2014-12-03 | ユナイテッド セラピューティクス コーポレイション | イミノ糖ならびにブニヤウイルスおよびトガウイルス疾患を治療する方法 |
| KR101459530B1 (ko) * | 2009-09-04 | 2014-11-07 | 유나이티드 세러퓨틱스 코오포레이션 | 폭스바이러스 감염의 치료 방법 |
| KR101497194B1 (ko) * | 2009-09-04 | 2015-02-27 | 유나이티드 세러퓨틱스 코오포레이션 | 오르토믹소바이러스 감염의 치료 방법 |
| JP5752689B2 (ja) * | 2009-09-04 | 2015-07-22 | ユナイテッド セラピューティクス コーポレイション | フィロウイルス疾患を治療するイミノ糖および方法 |
| GB201000499D0 (en) | 2010-01-13 | 2010-03-03 | Fleet George W J | Treatment of cystic fibrosis |
| WO2011095772A2 (en) | 2010-02-04 | 2011-08-11 | Summit Corporation Plc | Novel iminosugar therapeutics |
| GB201006434D0 (en) | 2010-04-19 | 2010-06-02 | Summit Corp Plc | Novel iminosugar combinations |
| EP3741384A1 (en) | 2011-09-07 | 2020-11-25 | Mount Sinai School Of Medicine | Ceramidase and cell differentiation |
| CN109529028A (zh) | 2012-06-01 | 2019-03-29 | 西奈山伊坎医学院 | 在感染的治疗和预防中的神经酰胺水平 |
| US20150346185A1 (en) * | 2012-12-05 | 2015-12-03 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Diagnosis of cystic fibrosis |
| WO2014160390A1 (en) | 2013-03-14 | 2014-10-02 | Icahn School Of Medicine At Mount Sinai | Therapeutic acid ceramidase compositions and methods of making and using them |
| WO2017178499A1 (en) | 2016-04-11 | 2017-10-19 | Spedding Research Solutions | Inhibitors of glucosylceramide degradation in the treatment of diseases of the motor units |
| RS67675B1 (sr) | 2017-06-01 | 2026-02-27 | Idorsia Pharmaceuticals Ltd | Kristalni oblik n‐butildeoksigalaktonojirimicina |
| BR112023018404A2 (pt) * | 2021-03-12 | 2023-11-28 | Excepgen Inc | Sistemas e métodos para expressão de proteína |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998002161A1 (en) | 1996-07-15 | 1998-01-22 | Universiteit Van Amsterdam | Deoxynojirimycin derivatives and their uses as glucosylceramidase inhibitors |
| AU5799500A (en) * | 1999-06-29 | 2001-01-22 | Mcgill University | Human alpha 1,2-mannosidase |
| EP1528056A1 (en) * | 2003-10-29 | 2005-05-04 | Academisch Ziekenhuis bij de Universiteit van Amsterdam | Deoxynojirimycin analogues and their uses as glucosylceramidase inhibitors |
| FR2861991B1 (fr) * | 2003-11-07 | 2008-01-18 | Centre Nat Rech Scient | Utilisation d'inhibiteurs de glucosidase pour une therapie de la mucoviscidose |
| WO2005123055A2 (en) * | 2004-06-14 | 2005-12-29 | Musc Foundation For Research Development | Methods for treating inflammatory disorders |
| CA2616537A1 (en) | 2005-07-27 | 2007-02-01 | University Of Florida Research Foundation, Inc. | Small compounds that correct protein misfolding and uses thereof |
-
2007
- 2007-04-24 AU AU2007241622A patent/AU2007241622A1/en not_active Abandoned
- 2007-04-24 CA CA002650311A patent/CA2650311A1/en not_active Abandoned
- 2007-04-24 JP JP2009507606A patent/JP2009538276A/ja not_active Ceased
- 2007-04-24 EP EP07747401A patent/EP2010551B1/en not_active Not-in-force
- 2007-04-24 AT AT07747401T patent/ATE479696T1/de not_active IP Right Cessation
- 2007-04-24 US US12/298,506 patent/US8410081B2/en not_active Expired - Fee Related
- 2007-04-24 CN CN2007800237886A patent/CN101479288B/zh not_active Expired - Fee Related
- 2007-04-24 BR BRPI0710883-4A patent/BRPI0710883A2/pt not_active IP Right Cessation
- 2007-04-24 WO PCT/NL2007/050177 patent/WO2007123403A1/en not_active Ceased
- 2007-04-24 DE DE602007008870T patent/DE602007008870D1/de active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ATE479696T1 (de) | 2010-09-15 |
| WO2007123403A1 (en) | 2007-11-01 |
| CN101479288B (zh) | 2012-06-27 |
| CN101479288A (zh) | 2009-07-08 |
| CA2650311A1 (en) | 2007-11-01 |
| US8410081B2 (en) | 2013-04-02 |
| AU2007241622A1 (en) | 2007-11-01 |
| DE602007008870D1 (de) | 2010-10-14 |
| EP2010551B1 (en) | 2010-09-01 |
| AU2007241622A8 (en) | 2008-12-04 |
| EP2010551A1 (en) | 2009-01-07 |
| US20090186862A1 (en) | 2009-07-23 |
| JP2009538276A (ja) | 2009-11-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 4A E 5A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE AS 4A E 5A ANUIDADES. |