JP2009537624A - 新規造影剤 - Google Patents
新規造影剤 Download PDFInfo
- Publication number
- JP2009537624A JP2009537624A JP2009511581A JP2009511581A JP2009537624A JP 2009537624 A JP2009537624 A JP 2009537624A JP 2009511581 A JP2009511581 A JP 2009511581A JP 2009511581 A JP2009511581 A JP 2009511581A JP 2009537624 A JP2009537624 A JP 2009537624A
- Authority
- JP
- Japan
- Prior art keywords
- contrast agent
- cbp
- peptide
- minutes
- precursor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 0 CC(C)(C(C)=NO)NCC*(CCN)CCNC(C)(C)C(C)=NO Chemical compound CC(C)(C(C)=NO)NCC*(CCN)CCNC(C)(C)C(C)=NO 0.000 description 1
- URDUFEZAWAZXBF-AABDNZFZSA-N CC(C)C[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](C)C(NCC(NC(CCC(O)=O)C(N)=O)=O)=O)=O)O)NC[C@H](C)C=O Chemical compound CC(C)C[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](C)C(NCC(NC(CCC(O)=O)C(N)=O)=O)=O)=O)O)NC[C@H](C)C=O URDUFEZAWAZXBF-AABDNZFZSA-N 0.000 description 1
- QUVCCGBDRNQLDD-UHFFFAOYSA-N CCC(C(N)=O)NC(C(Cc(cc1)ccc1O)NC(C(C(C)C)NC(C(CC(C)C)NC(C(CC(N)=O)NC(C(CC(C)C)NC(C(CCC(O)=O)NC(C(CCCCN)NNCCN)=O)=O)=O)O)=O)=O)=O Chemical compound CCC(C(N)=O)NC(C(Cc(cc1)ccc1O)NC(C(C(C)C)NC(C(CC(C)C)NC(C(CC(N)=O)NC(C(CC(C)C)NC(C(CCC(O)=O)NC(C(CCCCN)NNCCN)=O)=O)=O)O)=O)=O)=O QUVCCGBDRNQLDD-UHFFFAOYSA-N 0.000 description 1
- HTMOHBDLIMHIHH-BYPYZUCNSA-N C[C@@H](C(N)=O)NC(CCC(N)=O)=O Chemical compound C[C@@H](C(N)=O)NC(CCC(N)=O)=O HTMOHBDLIMHIHH-BYPYZUCNSA-N 0.000 description 1
- YKCAECKMIHVFLN-XMCUXHSSSA-N NCCCC[C@@H](CN[C@@H](CS)C(N)O)C=O Chemical compound NCCCC[C@@H](CN[C@@H](CS)C(N)O)C=O YKCAECKMIHVFLN-XMCUXHSSSA-N 0.000 description 1
- FNXAGGAFJKNNBN-UHFFFAOYSA-N NCCNCC(CC(NC1(CC1)C(N)=O)=O)CNCCN Chemical compound NCCNCC(CC(NC1(CC1)C(N)=O)=O)CNCCN FNXAGGAFJKNNBN-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0610395.6A GB0610395D0 (en) | 2006-05-25 | 2006-05-25 | Novel imaging agents |
| PCT/GB2007/001964 WO2007138291A2 (en) | 2006-05-25 | 2007-05-25 | Novel imaging agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009537624A true JP2009537624A (ja) | 2009-10-29 |
| JP2009537624A5 JP2009537624A5 (enExample) | 2010-06-17 |
Family
ID=36687722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009511581A Ceased JP2009537624A (ja) | 2006-05-25 | 2007-05-25 | 新規造影剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8304388B2 (enExample) |
| EP (1) | EP2026844A2 (enExample) |
| JP (1) | JP2009537624A (enExample) |
| CN (1) | CN101454026B (enExample) |
| BR (1) | BRPI0711937A2 (enExample) |
| GB (1) | GB0610395D0 (enExample) |
| RU (1) | RU2441668C2 (enExample) |
| WO (1) | WO2007138291A2 (enExample) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011128931A1 (ja) * | 2010-04-12 | 2011-10-20 | 財団法人ヒューマンサイエンス振興財団 | 歯髄炎診断マーカー及び歯髄炎診断システム |
| JP2016515620A (ja) * | 2013-04-02 | 2016-05-30 | プロタゴニスト セラピューティクス, インコーポレイテッド | 新規のα4β7ペプチド拮抗薬 |
| JP2016518351A (ja) * | 2013-04-02 | 2016-06-23 | プロタゴニスト セラピューティクス, インコーポレイテッド | 新規のα4β7ペプチド二量体アンタゴニスト |
| JP2018508492A (ja) * | 2015-01-30 | 2018-03-29 | ユニヴァーシティー オブ ユタ リサーチ ファウンデーション | 二量体のコラーゲンハイブリダイゼーションペプチドと使用方法 |
| WO2019044894A1 (ja) * | 2017-08-31 | 2019-03-07 | 学校法人早稲田大学 | コラーゲンへの結合活性を有する環状ペプチド |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8466258B2 (en) * | 2007-12-13 | 2013-06-18 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Polypeptides, cyclic polypeptides and pharmaceutical comprising thereof for non invasive specific imaging of fibrosis |
| LT2280720T (lt) * | 2008-03-27 | 2019-07-25 | Purdue Research Foundation | Kolageną surišantys sintetiniai peptidoglikanai, jų paruošimas ir naudojimo būdai |
| JP2010215572A (ja) * | 2009-03-17 | 2010-09-30 | Japan Health Science Foundation | 歯髄炎診断マーカー及び歯髄炎診断システム |
| US9173919B2 (en) * | 2011-02-16 | 2015-11-03 | Purdue Research Foundation | Collagen-targeted nanoparticles |
| PT2714718T (pt) | 2011-05-24 | 2017-04-19 | Symic Ip Llc | Preparação e métodos de utilização de peptidoglicanas sintéticas que se ligam a ácido hialurónico |
| WO2014055253A1 (en) * | 2012-10-04 | 2014-04-10 | The General Hospital Corporation | Methods of synthesizing and using peg-like fluorochromes |
| JP6603650B2 (ja) | 2013-03-15 | 2019-11-06 | パーデュー・リサーチ・ファウンデーション | 細胞外マトリックス結合性合成ペプチドグリカン |
| AU2014232954B2 (en) | 2013-03-15 | 2018-08-09 | Protagonist Therapeutics, Inc. | Hepcidin analogues and uses therof |
| US10772931B2 (en) | 2014-04-25 | 2020-09-15 | Purdue Research Foundation | Collagen binding synthetic peptidoglycans for treatment of endothelial dysfunction |
| ES2890600T3 (es) | 2014-05-16 | 2022-01-20 | Protagonist Therapeutics Inc | Péptidos de tioéter antagonistas de integrina alfa4beta7 |
| CN107206254B (zh) | 2014-07-17 | 2021-08-24 | 领导医疗有限公司 | 白细胞介素-23受体的口服肽抑制剂以及其治疗炎症性肠病的用途 |
| CA2962642A1 (en) | 2014-10-01 | 2016-04-07 | Protagonist Therapeutics, Inc. | Novel .alpha.4.beta.7 peptide monomer and dimer antagonists |
| US10301371B2 (en) | 2014-10-01 | 2019-05-28 | Protagonist Therapeutics, Inc. | Cyclic monomer and dimer peptides having integrin antagonist activity |
| US10787490B2 (en) | 2015-07-15 | 2020-09-29 | Protaganist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| US20190002503A1 (en) | 2015-12-30 | 2019-01-03 | Protagonist Therapeutics, Inc. | Analogues of hepcidin mimetics with improved in vivo half lives |
| EP3445402A4 (en) * | 2016-04-21 | 2019-12-11 | The Board Of Regents Of The University Of Texas System | METHOD AND COMPOSITIONS FOR DETECTING ANEURYSMS |
| EP3648774A4 (en) | 2017-07-07 | 2021-04-21 | Symic IP, LLC | SYNTHETIC BIOCONJUGATES |
| EP3681900A4 (en) | 2017-09-11 | 2021-09-08 | Protagonist Therapeutics, Inc. | OPIOID AGONIST PEPTIDES AND THEIR USES |
| EP4501952A3 (en) | 2018-02-08 | 2025-04-16 | Protagonist Therapeutics, Inc. | Conjugated hepcidin mimetics |
| CN116082455A (zh) | 2019-07-10 | 2023-05-09 | 领导医疗有限公司 | 白细胞介素-23受体的肽抑制剂及其用于治疗炎症性疾病的用途 |
| MA58373B1 (fr) | 2020-01-15 | 2025-07-31 | Janssen Biotech, Inc. | Inhibiteurs peptidiques du récepteur de l'interleukine-23 et leur utilisation pour traiter des maladies inflammatoires |
| WO2021146454A1 (en) | 2020-01-15 | 2021-07-22 | Janssen Biotech, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| MX2023005994A (es) | 2020-11-20 | 2023-08-11 | Janssen Pharmaceutica Nv | Composiciones de inhibidores peptidicos del receptor de interleucina-23. |
| EP4370146A4 (en) | 2021-07-14 | 2025-05-21 | Janssen Biotech, Inc. | Lipidated peptide inhibitors of the interleukin-23 receptor |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07505881A (ja) * | 1992-04-10 | 1995-06-29 | ザ ジェネラル ホスピタル コーポレイション | 軟骨基質たんぱく質及びその使用方法 |
| WO2005049005A1 (en) * | 2003-11-14 | 2005-06-02 | Ge Healthcare Limited | Inhibitor imaging agents |
| WO2005053752A2 (en) * | 2003-11-26 | 2005-06-16 | Ge Healthcare Limited | Novel imaging agents comprising caspase-3 inhibitors |
| WO2006020743A2 (en) * | 2004-08-13 | 2006-02-23 | General Electric Company | Heat shock protein as a targeting agent for endothelium-specific in vivo transduction |
| WO2006032911A2 (en) * | 2004-09-24 | 2006-03-30 | Ge Healthcare Limited | Metalloproteinase inhibitor imaging agents |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5972890A (en) | 1988-05-02 | 1999-10-26 | New England Deaconess Hospital Corporation | Synthetic peptides for arterial imaging |
| US7488792B2 (en) | 2002-08-28 | 2009-02-10 | Burnham Institute For Medical Research | Collagen-binding molecules that selectively home to tumor vasculature and methods of using same |
| CA2575416A1 (en) | 2004-02-27 | 2005-09-09 | The University Of Western Ontario | Bone sialoprotein collagen-binding peptides |
| RU2007118385A (ru) * | 2004-11-22 | 2008-12-27 | Джи-И Хелткер АС (NO) | Контрастные агенты для направлений доставки во внеклеточный матрикс |
-
2006
- 2006-05-25 GB GBGB0610395.6A patent/GB0610395D0/en not_active Ceased
-
2007
- 2007-05-25 JP JP2009511581A patent/JP2009537624A/ja not_active Ceased
- 2007-05-25 WO PCT/GB2007/001964 patent/WO2007138291A2/en not_active Ceased
- 2007-05-25 BR BRPI0711937-2A patent/BRPI0711937A2/pt not_active IP Right Cessation
- 2007-05-25 RU RU2008146031/15A patent/RU2441668C2/ru not_active IP Right Cessation
- 2007-05-25 US US12/302,290 patent/US8304388B2/en not_active Expired - Fee Related
- 2007-05-25 EP EP07732982A patent/EP2026844A2/en not_active Withdrawn
- 2007-05-25 CN CN2007800192052A patent/CN101454026B/zh not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07505881A (ja) * | 1992-04-10 | 1995-06-29 | ザ ジェネラル ホスピタル コーポレイション | 軟骨基質たんぱく質及びその使用方法 |
| WO2005049005A1 (en) * | 2003-11-14 | 2005-06-02 | Ge Healthcare Limited | Inhibitor imaging agents |
| WO2005053752A2 (en) * | 2003-11-26 | 2005-06-16 | Ge Healthcare Limited | Novel imaging agents comprising caspase-3 inhibitors |
| WO2006020743A2 (en) * | 2004-08-13 | 2006-02-23 | General Electric Company | Heat shock protein as a targeting agent for endothelium-specific in vivo transduction |
| WO2006032911A2 (en) * | 2004-09-24 | 2006-03-30 | Ge Healthcare Limited | Metalloproteinase inhibitor imaging agents |
Non-Patent Citations (4)
| Title |
|---|
| JPN5009009192; CHIANG THOMAS M: THE AMERICAN JOURNAL OF THE MEDICAL SCIENCES V320 N6, 200012, P362-367 * |
| JPN6012028752; Analytical Biochemistry Vol.350, No.2, 20060315, p.177-185 * |
| JPN6012028753; The Journal of Clinical Investigation Vol.100, No.8, 1997, p.2079-2084 * |
| JPN6012028755; The Journal of Biological Chemistry Vol.277, No.38, 2002, p.34896-34901 * |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011128931A1 (ja) * | 2010-04-12 | 2011-10-20 | 財団法人ヒューマンサイエンス振興財団 | 歯髄炎診断マーカー及び歯髄炎診断システム |
| JP2016515620A (ja) * | 2013-04-02 | 2016-05-30 | プロタゴニスト セラピューティクス, インコーポレイテッド | 新規のα4β7ペプチド拮抗薬 |
| JP2016518351A (ja) * | 2013-04-02 | 2016-06-23 | プロタゴニスト セラピューティクス, インコーポレイテッド | 新規のα4β7ペプチド二量体アンタゴニスト |
| JP2018508492A (ja) * | 2015-01-30 | 2018-03-29 | ユニヴァーシティー オブ ユタ リサーチ ファウンデーション | 二量体のコラーゲンハイブリダイゼーションペプチドと使用方法 |
| JP2021152004A (ja) * | 2015-01-30 | 2021-09-30 | ユニヴァーシティー オブ ユタ リサーチ ファウンデーション | 二量体のコラーゲンハイブリダイゼーションペプチドと使用方法 |
| US11684675B2 (en) | 2015-01-30 | 2023-06-27 | University Of Utah Research Foundation | Dimeric collagen hybridizing peptides and methods of using |
| WO2019044894A1 (ja) * | 2017-08-31 | 2019-03-07 | 学校法人早稲田大学 | コラーゲンへの結合活性を有する環状ペプチド |
| JPWO2019044894A1 (ja) * | 2017-08-31 | 2020-10-08 | 学校法人早稲田大学 | コラーゲンへの結合活性を有する環状ペプチド |
| JP7174429B2 (ja) | 2017-08-31 | 2022-11-17 | 学校法人早稲田大学 | コラーゲンへの結合活性を有する環状ペプチド |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2026844A2 (en) | 2009-02-25 |
| WO2007138291A3 (en) | 2008-05-29 |
| RU2008146031A (ru) | 2010-06-27 |
| US8304388B2 (en) | 2012-11-06 |
| US20090191123A1 (en) | 2009-07-30 |
| CN101454026A (zh) | 2009-06-10 |
| GB0610395D0 (en) | 2006-07-05 |
| CN101454026B (zh) | 2012-12-12 |
| RU2441668C2 (ru) | 2012-02-10 |
| BRPI0711937A2 (pt) | 2012-07-24 |
| WO2007138291A2 (en) | 2007-12-06 |
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