JP2009537624A - 新規造影剤 - Google Patents

新規造影剤 Download PDF

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Publication number
JP2009537624A
JP2009537624A JP2009511581A JP2009511581A JP2009537624A JP 2009537624 A JP2009537624 A JP 2009537624A JP 2009511581 A JP2009511581 A JP 2009511581A JP 2009511581 A JP2009511581 A JP 2009511581A JP 2009537624 A JP2009537624 A JP 2009537624A
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JP
Japan
Prior art keywords
contrast agent
cbp
peptide
minutes
precursor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2009511581A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009537624A5 (enExample
Inventor
チェティッビ,サラー
ニュートン,ベン
ハスビン,メッテ
ソルバッケン,マグネ
バラ,ラジーヴ
ブラウン,ジェーン
イヴェソン,ピーター
クレイマー,ダニエル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
GE Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Ltd filed Critical GE Healthcare Ltd
Publication of JP2009537624A publication Critical patent/JP2009537624A/ja
Publication of JP2009537624A5 publication Critical patent/JP2009537624A5/ja
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0002General or multifunctional contrast agents, e.g. chelated agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
JP2009511581A 2006-05-25 2007-05-25 新規造影剤 Ceased JP2009537624A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0610395.6A GB0610395D0 (en) 2006-05-25 2006-05-25 Novel imaging agents
PCT/GB2007/001964 WO2007138291A2 (en) 2006-05-25 2007-05-25 Novel imaging agents

Publications (2)

Publication Number Publication Date
JP2009537624A true JP2009537624A (ja) 2009-10-29
JP2009537624A5 JP2009537624A5 (enExample) 2010-06-17

Family

ID=36687722

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009511581A Ceased JP2009537624A (ja) 2006-05-25 2007-05-25 新規造影剤

Country Status (8)

Country Link
US (1) US8304388B2 (enExample)
EP (1) EP2026844A2 (enExample)
JP (1) JP2009537624A (enExample)
CN (1) CN101454026B (enExample)
BR (1) BRPI0711937A2 (enExample)
GB (1) GB0610395D0 (enExample)
RU (1) RU2441668C2 (enExample)
WO (1) WO2007138291A2 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011128931A1 (ja) * 2010-04-12 2011-10-20 財団法人ヒューマンサイエンス振興財団 歯髄炎診断マーカー及び歯髄炎診断システム
JP2016515620A (ja) * 2013-04-02 2016-05-30 プロタゴニスト セラピューティクス, インコーポレイテッド 新規のα4β7ペプチド拮抗薬
JP2016518351A (ja) * 2013-04-02 2016-06-23 プロタゴニスト セラピューティクス, インコーポレイテッド 新規のα4β7ペプチド二量体アンタゴニスト
JP2018508492A (ja) * 2015-01-30 2018-03-29 ユニヴァーシティー オブ ユタ リサーチ ファウンデーション 二量体のコラーゲンハイブリダイゼーションペプチドと使用方法
WO2019044894A1 (ja) * 2017-08-31 2019-03-07 学校法人早稲田大学 コラーゲンへの結合活性を有する環状ペプチド

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8466258B2 (en) * 2007-12-13 2013-06-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Polypeptides, cyclic polypeptides and pharmaceutical comprising thereof for non invasive specific imaging of fibrosis
LT2280720T (lt) * 2008-03-27 2019-07-25 Purdue Research Foundation Kolageną surišantys sintetiniai peptidoglikanai, jų paruošimas ir naudojimo būdai
JP2010215572A (ja) * 2009-03-17 2010-09-30 Japan Health Science Foundation 歯髄炎診断マーカー及び歯髄炎診断システム
US9173919B2 (en) * 2011-02-16 2015-11-03 Purdue Research Foundation Collagen-targeted nanoparticles
PT2714718T (pt) 2011-05-24 2017-04-19 Symic Ip Llc Preparação e métodos de utilização de peptidoglicanas sintéticas que se ligam a ácido hialurónico
WO2014055253A1 (en) * 2012-10-04 2014-04-10 The General Hospital Corporation Methods of synthesizing and using peg-like fluorochromes
JP6603650B2 (ja) 2013-03-15 2019-11-06 パーデュー・リサーチ・ファウンデーション 細胞外マトリックス結合性合成ペプチドグリカン
AU2014232954B2 (en) 2013-03-15 2018-08-09 Protagonist Therapeutics, Inc. Hepcidin analogues and uses therof
US10772931B2 (en) 2014-04-25 2020-09-15 Purdue Research Foundation Collagen binding synthetic peptidoglycans for treatment of endothelial dysfunction
ES2890600T3 (es) 2014-05-16 2022-01-20 Protagonist Therapeutics Inc Péptidos de tioéter antagonistas de integrina alfa4beta7
CN107206254B (zh) 2014-07-17 2021-08-24 领导医疗有限公司 白细胞介素-23受体的口服肽抑制剂以及其治疗炎症性肠病的用途
CA2962642A1 (en) 2014-10-01 2016-04-07 Protagonist Therapeutics, Inc. Novel .alpha.4.beta.7 peptide monomer and dimer antagonists
US10301371B2 (en) 2014-10-01 2019-05-28 Protagonist Therapeutics, Inc. Cyclic monomer and dimer peptides having integrin antagonist activity
US10787490B2 (en) 2015-07-15 2020-09-29 Protaganist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
US20190002503A1 (en) 2015-12-30 2019-01-03 Protagonist Therapeutics, Inc. Analogues of hepcidin mimetics with improved in vivo half lives
EP3445402A4 (en) * 2016-04-21 2019-12-11 The Board Of Regents Of The University Of Texas System METHOD AND COMPOSITIONS FOR DETECTING ANEURYSMS
EP3648774A4 (en) 2017-07-07 2021-04-21 Symic IP, LLC SYNTHETIC BIOCONJUGATES
EP3681900A4 (en) 2017-09-11 2021-09-08 Protagonist Therapeutics, Inc. OPIOID AGONIST PEPTIDES AND THEIR USES
EP4501952A3 (en) 2018-02-08 2025-04-16 Protagonist Therapeutics, Inc. Conjugated hepcidin mimetics
CN116082455A (zh) 2019-07-10 2023-05-09 领导医疗有限公司 白细胞介素-23受体的肽抑制剂及其用于治疗炎症性疾病的用途
MA58373B1 (fr) 2020-01-15 2025-07-31 Janssen Biotech, Inc. Inhibiteurs peptidiques du récepteur de l'interleukine-23 et leur utilisation pour traiter des maladies inflammatoires
WO2021146454A1 (en) 2020-01-15 2021-07-22 Janssen Biotech, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
MX2023005994A (es) 2020-11-20 2023-08-11 Janssen Pharmaceutica Nv Composiciones de inhibidores peptidicos del receptor de interleucina-23.
EP4370146A4 (en) 2021-07-14 2025-05-21 Janssen Biotech, Inc. Lipidated peptide inhibitors of the interleukin-23 receptor

Citations (5)

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Publication number Priority date Publication date Assignee Title
JPH07505881A (ja) * 1992-04-10 1995-06-29 ザ ジェネラル ホスピタル コーポレイション 軟骨基質たんぱく質及びその使用方法
WO2005049005A1 (en) * 2003-11-14 2005-06-02 Ge Healthcare Limited Inhibitor imaging agents
WO2005053752A2 (en) * 2003-11-26 2005-06-16 Ge Healthcare Limited Novel imaging agents comprising caspase-3 inhibitors
WO2006020743A2 (en) * 2004-08-13 2006-02-23 General Electric Company Heat shock protein as a targeting agent for endothelium-specific in vivo transduction
WO2006032911A2 (en) * 2004-09-24 2006-03-30 Ge Healthcare Limited Metalloproteinase inhibitor imaging agents

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US5972890A (en) 1988-05-02 1999-10-26 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging
US7488792B2 (en) 2002-08-28 2009-02-10 Burnham Institute For Medical Research Collagen-binding molecules that selectively home to tumor vasculature and methods of using same
CA2575416A1 (en) 2004-02-27 2005-09-09 The University Of Western Ontario Bone sialoprotein collagen-binding peptides
RU2007118385A (ru) * 2004-11-22 2008-12-27 Джи-И Хелткер АС (NO) Контрастные агенты для направлений доставки во внеклеточный матрикс

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07505881A (ja) * 1992-04-10 1995-06-29 ザ ジェネラル ホスピタル コーポレイション 軟骨基質たんぱく質及びその使用方法
WO2005049005A1 (en) * 2003-11-14 2005-06-02 Ge Healthcare Limited Inhibitor imaging agents
WO2005053752A2 (en) * 2003-11-26 2005-06-16 Ge Healthcare Limited Novel imaging agents comprising caspase-3 inhibitors
WO2006020743A2 (en) * 2004-08-13 2006-02-23 General Electric Company Heat shock protein as a targeting agent for endothelium-specific in vivo transduction
WO2006032911A2 (en) * 2004-09-24 2006-03-30 Ge Healthcare Limited Metalloproteinase inhibitor imaging agents

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JPN5009009192; CHIANG THOMAS M: THE AMERICAN JOURNAL OF THE MEDICAL SCIENCES V320 N6, 200012, P362-367 *
JPN6012028752; Analytical Biochemistry Vol.350, No.2, 20060315, p.177-185 *
JPN6012028753; The Journal of Clinical Investigation Vol.100, No.8, 1997, p.2079-2084 *
JPN6012028755; The Journal of Biological Chemistry Vol.277, No.38, 2002, p.34896-34901 *

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011128931A1 (ja) * 2010-04-12 2011-10-20 財団法人ヒューマンサイエンス振興財団 歯髄炎診断マーカー及び歯髄炎診断システム
JP2016515620A (ja) * 2013-04-02 2016-05-30 プロタゴニスト セラピューティクス, インコーポレイテッド 新規のα4β7ペプチド拮抗薬
JP2016518351A (ja) * 2013-04-02 2016-06-23 プロタゴニスト セラピューティクス, インコーポレイテッド 新規のα4β7ペプチド二量体アンタゴニスト
JP2018508492A (ja) * 2015-01-30 2018-03-29 ユニヴァーシティー オブ ユタ リサーチ ファウンデーション 二量体のコラーゲンハイブリダイゼーションペプチドと使用方法
JP2021152004A (ja) * 2015-01-30 2021-09-30 ユニヴァーシティー オブ ユタ リサーチ ファウンデーション 二量体のコラーゲンハイブリダイゼーションペプチドと使用方法
US11684675B2 (en) 2015-01-30 2023-06-27 University Of Utah Research Foundation Dimeric collagen hybridizing peptides and methods of using
WO2019044894A1 (ja) * 2017-08-31 2019-03-07 学校法人早稲田大学 コラーゲンへの結合活性を有する環状ペプチド
JPWO2019044894A1 (ja) * 2017-08-31 2020-10-08 学校法人早稲田大学 コラーゲンへの結合活性を有する環状ペプチド
JP7174429B2 (ja) 2017-08-31 2022-11-17 学校法人早稲田大学 コラーゲンへの結合活性を有する環状ペプチド

Also Published As

Publication number Publication date
EP2026844A2 (en) 2009-02-25
WO2007138291A3 (en) 2008-05-29
RU2008146031A (ru) 2010-06-27
US8304388B2 (en) 2012-11-06
US20090191123A1 (en) 2009-07-30
CN101454026A (zh) 2009-06-10
GB0610395D0 (en) 2006-07-05
CN101454026B (zh) 2012-12-12
RU2441668C2 (ru) 2012-02-10
BRPI0711937A2 (pt) 2012-07-24
WO2007138291A2 (en) 2007-12-06

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