RU2441668C2 - Новые визуализирующие агенты - Google Patents

Новые визуализирующие агенты Download PDF

Info

Publication number
RU2441668C2
RU2441668C2 RU2008146031/15A RU2008146031A RU2441668C2 RU 2441668 C2 RU2441668 C2 RU 2441668C2 RU 2008146031/15 A RU2008146031/15 A RU 2008146031/15A RU 2008146031 A RU2008146031 A RU 2008146031A RU 2441668 C2 RU2441668 C2 RU 2441668C2
Authority
RU
Russia
Prior art keywords
imaging
agent
collagen
pharmaceutical composition
cbp
Prior art date
Application number
RU2008146031/15A
Other languages
English (en)
Russian (ru)
Other versions
RU2008146031A (ru
Inventor
Сала ЧЕТТИБИ (GB)
Сала ЧЕТТИБИ
Бен НЬЮТОН (GB)
Бен НЬЮТОН
Метт ХАСБИН (NO)
Метт ХАСБИН
Магне СОЛЬБАККЕН (NO)
Магне СОЛЬБАККЕН
Питер ИВСОН (GB)
Питер ИВСОН
Джейн БРАУН (GB)
Джейн БРАУН
Раджив БХАЛЛА (GB)
Раджив БХАЛЛА
Дэниэл КРАМЕР (US)
Дэниэл КРАМЕР
Original Assignee
Джи-И Хелткер Лимитед
Джи-И Хелткер АС
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Джи-И Хелткер Лимитед, Джи-И Хелткер АС filed Critical Джи-И Хелткер Лимитед
Publication of RU2008146031A publication Critical patent/RU2008146031A/ru
Application granted granted Critical
Publication of RU2441668C2 publication Critical patent/RU2441668C2/ru

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
RU2008146031/15A 2006-05-25 2007-05-25 Новые визуализирующие агенты RU2441668C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0610395.6A GB0610395D0 (en) 2006-05-25 2006-05-25 Novel imaging agents
GB0610395.6 2006-05-25

Publications (2)

Publication Number Publication Date
RU2008146031A RU2008146031A (ru) 2010-06-27
RU2441668C2 true RU2441668C2 (ru) 2012-02-10

Family

ID=36687722

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2008146031/15A RU2441668C2 (ru) 2006-05-25 2007-05-25 Новые визуализирующие агенты

Country Status (8)

Country Link
US (1) US8304388B2 (enExample)
EP (1) EP2026844A2 (enExample)
JP (1) JP2009537624A (enExample)
CN (1) CN101454026B (enExample)
BR (1) BRPI0711937A2 (enExample)
GB (1) GB0610395D0 (enExample)
RU (1) RU2441668C2 (enExample)
WO (1) WO2007138291A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014055253A1 (en) * 2012-10-04 2014-04-10 The General Hospital Corporation Methods of synthesizing and using peg-like fluorochromes

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8466258B2 (en) * 2007-12-13 2013-06-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Polypeptides, cyclic polypeptides and pharmaceutical comprising thereof for non invasive specific imaging of fibrosis
LT2280720T (lt) * 2008-03-27 2019-07-25 Purdue Research Foundation Kolageną surišantys sintetiniai peptidoglikanai, jų paruošimas ir naudojimo būdai
JP2010215572A (ja) * 2009-03-17 2010-09-30 Japan Health Science Foundation 歯髄炎診断マーカー及び歯髄炎診断システム
WO2011128931A1 (ja) * 2010-04-12 2011-10-20 財団法人ヒューマンサイエンス振興財団 歯髄炎診断マーカー及び歯髄炎診断システム
US9173919B2 (en) * 2011-02-16 2015-11-03 Purdue Research Foundation Collagen-targeted nanoparticles
PT2714718T (pt) 2011-05-24 2017-04-19 Symic Ip Llc Preparação e métodos de utilização de peptidoglicanas sintéticas que se ligam a ácido hialurónico
JP6603650B2 (ja) 2013-03-15 2019-11-06 パーデュー・リサーチ・ファウンデーション 細胞外マトリックス結合性合成ペプチドグリカン
AU2014232954B2 (en) 2013-03-15 2018-08-09 Protagonist Therapeutics, Inc. Hepcidin analogues and uses therof
US20140294901A1 (en) * 2013-04-02 2014-10-02 Protagonist Therapeutics, Inc. Novel a4b7 peptide dimer antagonists
US20140294902A1 (en) * 2013-04-02 2014-10-02 Protagonist Therapeutics, Inc. Novel a4b7 peptide antagonists
US10772931B2 (en) 2014-04-25 2020-09-15 Purdue Research Foundation Collagen binding synthetic peptidoglycans for treatment of endothelial dysfunction
ES2890600T3 (es) 2014-05-16 2022-01-20 Protagonist Therapeutics Inc Péptidos de tioéter antagonistas de integrina alfa4beta7
CN107206254B (zh) 2014-07-17 2021-08-24 领导医疗有限公司 白细胞介素-23受体的口服肽抑制剂以及其治疗炎症性肠病的用途
CA2962642A1 (en) 2014-10-01 2016-04-07 Protagonist Therapeutics, Inc. Novel .alpha.4.beta.7 peptide monomer and dimer antagonists
US10301371B2 (en) 2014-10-01 2019-05-28 Protagonist Therapeutics, Inc. Cyclic monomer and dimer peptides having integrin antagonist activity
WO2016123570A1 (en) 2015-01-30 2016-08-04 University Of Utah Research Foundation Dimeric collagen hybridizing peptides and methods of using
US10787490B2 (en) 2015-07-15 2020-09-29 Protaganist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
US20190002503A1 (en) 2015-12-30 2019-01-03 Protagonist Therapeutics, Inc. Analogues of hepcidin mimetics with improved in vivo half lives
EP3445402A4 (en) * 2016-04-21 2019-12-11 The Board Of Regents Of The University Of Texas System METHOD AND COMPOSITIONS FOR DETECTING ANEURYSMS
EP3648774A4 (en) 2017-07-07 2021-04-21 Symic IP, LLC SYNTHETIC BIOCONJUGATES
WO2019044894A1 (ja) * 2017-08-31 2019-03-07 学校法人早稲田大学 コラーゲンへの結合活性を有する環状ペプチド
EP3681900A4 (en) 2017-09-11 2021-09-08 Protagonist Therapeutics, Inc. OPIOID AGONIST PEPTIDES AND THEIR USES
EP4501952A3 (en) 2018-02-08 2025-04-16 Protagonist Therapeutics, Inc. Conjugated hepcidin mimetics
CN116082455A (zh) 2019-07-10 2023-05-09 领导医疗有限公司 白细胞介素-23受体的肽抑制剂及其用于治疗炎症性疾病的用途
MA58373B1 (fr) 2020-01-15 2025-07-31 Janssen Biotech, Inc. Inhibiteurs peptidiques du récepteur de l'interleukine-23 et leur utilisation pour traiter des maladies inflammatoires
WO2021146454A1 (en) 2020-01-15 2021-07-22 Janssen Biotech, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
MX2023005994A (es) 2020-11-20 2023-08-11 Janssen Pharmaceutica Nv Composiciones de inhibidores peptidicos del receptor de interleucina-23.
EP4370146A4 (en) 2021-07-14 2025-05-21 Janssen Biotech, Inc. Lipidated peptide inhibitors of the interleukin-23 receptor

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5741670A (en) * 1992-04-10 1998-04-21 The General Hospital Corporation Cartilage matrix protein and methods for use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972890A (en) 1988-05-02 1999-10-26 New England Deaconess Hospital Corporation Synthetic peptides for arterial imaging
US7488792B2 (en) 2002-08-28 2009-02-10 Burnham Institute For Medical Research Collagen-binding molecules that selectively home to tumor vasculature and methods of using same
GB0326546D0 (en) * 2003-11-14 2003-12-17 Amersham Plc Inhibitor imaging agents
GB0327494D0 (en) 2003-11-26 2003-12-31 Amersham Plc Novel imaging agents
CA2575416A1 (en) 2004-02-27 2005-09-09 The University Of Western Ontario Bone sialoprotein collagen-binding peptides
US7575738B2 (en) * 2004-08-13 2009-08-18 General Electric Company Heat shock protein as a targeting agent for endothelium-specific in vivo transduction
GB0421308D0 (en) * 2004-09-24 2004-10-27 Amersham Plc Enzyme inhibitor imaging agents
RU2007118385A (ru) * 2004-11-22 2008-12-27 Джи-И Хелткер АС (NO) Контрастные агенты для направлений доставки во внеклеточный матрикс

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5741670A (en) * 1992-04-10 1998-04-21 The General Hospital Corporation Cartilage matrix protein and methods for use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Thomas M. Chiang et al. "A Synthetic Peptide Derived from the Sequence of a Type I Collagen Receptor Inhibits Type I Collagen-mediated Platelet Aggregation", The Journal of Clinical Investigation, Volume 100, number 8, October 1997, 2079-2084. Thomas M. Chiang et al. "Cloning, Characterization, and Functional Studies *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014055253A1 (en) * 2012-10-04 2014-04-10 The General Hospital Corporation Methods of synthesizing and using peg-like fluorochromes

Also Published As

Publication number Publication date
EP2026844A2 (en) 2009-02-25
WO2007138291A3 (en) 2008-05-29
RU2008146031A (ru) 2010-06-27
US8304388B2 (en) 2012-11-06
JP2009537624A (ja) 2009-10-29
US20090191123A1 (en) 2009-07-30
CN101454026A (zh) 2009-06-10
GB0610395D0 (en) 2006-07-05
CN101454026B (zh) 2012-12-12
BRPI0711937A2 (pt) 2012-07-24
WO2007138291A2 (en) 2007-12-06

Similar Documents

Publication Publication Date Title
RU2441668C2 (ru) Новые визуализирующие агенты
BRPI0507684A (pt) agentes de contraste para formação de imagem de perfusão miocárdica
CA2452923A1 (en) Peptide-based compounds for targeting integrin receptors
BRPI0510487A (pt) agentes de contraste para estudo por imagens de perfusão do miocárdio
MA30474B1 (fr) Formulations de molecule peptide(s) -anticorps therapeutique lyophilisee.
EP2305316A3 (en) Diphosphorylated glycopeptide imaging agent for fibrosis
CY1112738T1 (el) Μια συνδυασμενη συνθεση που περιεχει ιβουπροφαινη και παρακεταμολη
WO2011094337A8 (en) Glucagon antagonist - gip agonist conjugates and compositions for the treatment of metabolic disorders and obesity
EP4541418A3 (en) Assays for diagnosing and evaluating treatment options for fabry disease
EA200601524A1 (ru) Альфа-излучающие частицы гидроксиапатита
GT200600288A (es) Composiciones que contienen particulas magneticas de oxido de hierro, y uso de dichas composiciones en metodos de diagnostico por imagenes
PH12013500270A1 (en) Peptide radiotracer compositions
ATE555814T1 (de) Radioaktive mittel für die in vivo pet-bildgebung von ccr5
EP2359864A3 (en) Targeting Vector-Phospholipid Conjugates
DOP2006000153A (es) Composiciones que contienen partículas magnéticas de óxido de hierro, y uso de dichas composiciones en métodos de diagnóstico por imágenes
WO2005053615A8 (en) Novel differential imaging method
JP2010502585A5 (enExample)
GB201103696D0 (en) Technetium labelled peptides
EP1698351A3 (en) Glycopeptide compositions
BRPI0515894A (pt) agente de formação de imagem, composições farmacêutica e radiofarmacêutica, conjugado de um inibidor de metaloproteinase matricial com um ligando, precursor para a preparação da composição radiofarmacêutica, kit para a preparação da composição radiofarmacêutica, e, uso do agente de formação de imagem
WO2007066119A3 (en) Novel imaging agents for fibrosis
BR112013006536A2 (pt) agente de formação de imagem, conjugado quelador, métodos de preparação do agente de formação de imagem, de formar imagem do corpo humano ou de animal e de diagnóstico do corpo humano ou animal, composição radiofarmacêutica, kit para a preparação da composição radiofarmacêutica, e, uso do agente de formação de imagem, da composição ou do kit
GB0403856D0 (en) Composition
TW200744645A (en) Contrast agents for myocardium perfusion imaging
TW200628170A (en) Contrast agents for myocardial perfusion imaging

Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20130526