JP2009533433A - ピルビン酸アルキルエステルを含む組成物とその使用 - Google Patents
ピルビン酸アルキルエステルを含む組成物とその使用 Download PDFInfo
- Publication number
- JP2009533433A JP2009533433A JP2009505389A JP2009505389A JP2009533433A JP 2009533433 A JP2009533433 A JP 2009533433A JP 2009505389 A JP2009505389 A JP 2009505389A JP 2009505389 A JP2009505389 A JP 2009505389A JP 2009533433 A JP2009533433 A JP 2009533433A
- Authority
- JP
- Japan
- Prior art keywords
- composition
- pyruvate
- effective amount
- ingesting
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Neurology (AREA)
- Mycology (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Neurosurgery (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74473906P | 2006-04-12 | 2006-04-12 | |
| PCT/US2007/008334 WO2007120544A2 (en) | 2006-04-12 | 2007-04-04 | Compositions comprising pyruvate alkyl esters and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009533433A true JP2009533433A (ja) | 2009-09-17 |
| JP2009533433A5 JP2009533433A5 (cg-RX-API-DMAC7.html) | 2010-05-13 |
Family
ID=38610076
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009505389A Pending JP2009533433A (ja) | 2006-04-12 | 2007-04-04 | ピルビン酸アルキルエステルを含む組成物とその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20100047221A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2010218B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2009533433A (cg-RX-API-DMAC7.html) |
| CN (1) | CN101472613A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007238938B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2683664C (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ572649A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2007120544A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120046361A1 (en) * | 2010-08-20 | 2012-02-23 | American Symbolic, Llc | Ethyl pyruvate compositions and methods |
| CN113876014B (zh) * | 2021-09-06 | 2022-10-18 | 湖北中烟工业有限责任公司 | 一种含有烷基化甘油的雾化剂及其制备方法和应用 |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003510357A (ja) * | 1999-10-07 | 2003-03-18 | キサンタス ライフ サイエンシズ,インコーポレイテッド | ピルビン酸エステル組成物ならびに虚血および再灌流の事象後の蘇生のための使用法 |
| JP2004528307A (ja) * | 2001-03-15 | 2004-09-16 | ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション | サイトカインにより媒介される炎症性状態の治療のためのピルベートおよび/またはその誘導体の使用方法 |
| WO2005002563A2 (en) * | 2003-06-13 | 2005-01-13 | University Of Pittsburgh - Of The Commonwealth System Of Higher Eduction | Method for treating alcoholic hepatitis |
| WO2005044299A1 (en) * | 2003-10-27 | 2005-05-19 | University Of Pennsylvania | Cytoprotective effects of ethyl pyruvate |
| JP2005526832A (ja) * | 2002-04-17 | 2005-09-08 | クリティカル セラピューティクス,インコーポレイテッド | α−ケトアルカン酸エステルまたは−アミドおよび乳酸または乳酸塩を含有する医薬組成物 |
| WO2005094236A2 (en) * | 2003-11-07 | 2005-10-13 | Henry M. Jackson Foundation | Activation of hypoxia-inducible gene expression |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4158057A (en) * | 1975-03-28 | 1979-06-12 | Stanko Ronald T | Prevention of the accumulation of fatty deposits in the liver |
| GB1603724A (en) * | 1977-05-25 | 1981-11-25 | Montedison Spa | Components and catalysts for the polymerisation of alpha-olefins |
| US4174742A (en) * | 1978-02-08 | 1979-11-20 | Murphey James D | Method and apparatus for making and dispensing snow cones |
| US4491597A (en) | 1981-01-26 | 1985-01-01 | Scm Corporation | Candy bar |
| US4351835A (en) | 1981-04-01 | 1982-09-28 | Montefiore Hospital | Method for preventing body fat deposition in mammals |
| US4415576A (en) * | 1981-04-01 | 1983-11-15 | Montefiore Hospital | Method for preventing body fat deposition in mammals |
| US4548937A (en) | 1981-04-01 | 1985-10-22 | Montefiore Hospital | Method for preventing body fat deposition in mammals |
| US4812479A (en) * | 1981-04-01 | 1989-03-14 | The Montefiore Hospital Society Of Western Pennsylvania, Inc. | Method for preventing body fat deposition in mammals |
| JPS59104326A (ja) * | 1982-12-04 | 1984-06-16 | Toyo Jozo Co Ltd | マクロライド抗生物質の安定な経口用製剤および安定化法 |
| US5389677B1 (en) * | 1986-12-23 | 1997-07-15 | Tristrata Inc | Method of treating wrinkles using glycalic acid |
| US4981687A (en) * | 1988-07-29 | 1991-01-01 | University Of Florida | Compositions and methods for achieving improved physiological response to exercise |
| US5236712A (en) * | 1988-07-29 | 1993-08-17 | University Of Florida | Compositions and methods for achieving improved physiological response to exercise |
| US4874790A (en) * | 1988-08-15 | 1989-10-17 | Montefiore Hospital Association Of Western Pennsylvania | Method for improving the glucose metabolism of an animal having diabetic tendencies |
| US5134162A (en) * | 1990-12-24 | 1992-07-28 | The Montefiore Hospital Association Of Western Pennsylvania | Method for lowering high blood cholesterol levels in hyperlipidemic animals and confections as the ingestion medium |
| US5294641A (en) | 1991-11-27 | 1994-03-15 | Montefiore - University Hospital | Method for treating a medical patient for cardiac trauma |
| US5256597A (en) * | 1992-09-04 | 1993-10-26 | International Business Machines Corporation | Self-aligned conducting etch stop for interconnect patterning |
| SE9303691D0 (sv) * | 1993-11-09 | 1993-11-09 | Gramineer Ab | New beverage |
| US5612374A (en) * | 1994-02-14 | 1997-03-18 | Ronald T. Stanko | Inhibiting growth of mammary adenocarcinoma |
| US5480909A (en) * | 1994-08-08 | 1996-01-02 | University Of Pittsburgh Medical Center | Method for inhibiting generation of free-radicals |
| US5621996A (en) | 1995-06-07 | 1997-04-22 | Pride Cast Metals, Inc. | Combination security and display device for firearms |
| US5801198A (en) | 1995-07-13 | 1998-09-01 | University Of Pittsburgh Medical Center | Retarding neutrophil infiltration ad morphologic reduction in ischemic bowel tissues |
| US5876916A (en) * | 1996-03-18 | 1999-03-02 | Case Western Reserve University | Pyruvate compounds and methods for use thereof |
| US5716926A (en) * | 1996-07-26 | 1998-02-10 | Paxton K. Beale | Composition of pyruvate and protein and method for increasing protein concentration in a mammal |
| US6417231B1 (en) * | 1996-12-23 | 2002-07-09 | Frank L. Greenway | Method and composition for delivering therapeutically effective amounts of pyruvate to a mammal |
| US5973005A (en) * | 1998-02-26 | 1999-10-26 | Bio-Bontanica, Inc. | Aqueous creatine solution and process of producing a stable, bioavailable aqueous creatine solution |
| US5976550A (en) * | 1998-11-20 | 1999-11-02 | Engel; Peter H. | Dietary food supplement |
| US6846842B2 (en) * | 1999-10-07 | 2005-01-25 | Beth Israel Deconess Medical Center, Inc. | Pyruvate ester composition and method of use for resuscitation after events of ischemia and reperfusion |
| GB0011676D0 (en) * | 2000-05-15 | 2000-07-05 | Unilever Plc | Ambient stable beverage |
| GB0011674D0 (en) * | 2000-05-15 | 2000-07-05 | Unilever Plc | Ambient stable beverage |
| GB0011675D0 (en) * | 2000-05-15 | 2000-07-05 | Unilever Plc | Ambient stable beverage |
| US20060025475A1 (en) * | 2004-07-29 | 2006-02-02 | Stanley Antosh | Use of methyl pyruvate for the purpose of increasing muscle energy production. |
| US20100204161A1 (en) | 2005-04-15 | 2010-08-12 | Biomac Privatinstitut Fur Medizinishe Und Zahmediz Forschung, Entwicklung Und Diagnostik Gmbh | Substances and Pharmaceutical Compositions for the Inhibition of Glyoxalases and Their Use Against Bacteria |
| US20080153897A1 (en) * | 2006-09-11 | 2008-06-26 | New Cell Formulations Ltd. | Creatine pyroglutamic acid salts and methods for their production and use in individuals |
-
2007
- 2007-04-04 US US12/296,527 patent/US20100047221A1/en not_active Abandoned
- 2007-04-04 NZ NZ572649A patent/NZ572649A/en not_active IP Right Cessation
- 2007-04-04 AU AU2007238938A patent/AU2007238938B2/en not_active Ceased
- 2007-04-04 EP EP07754798.2A patent/EP2010218B1/en not_active Not-in-force
- 2007-04-04 JP JP2009505389A patent/JP2009533433A/ja active Pending
- 2007-04-04 CN CNA2007800216659A patent/CN101472613A/zh active Pending
- 2007-04-04 WO PCT/US2007/008334 patent/WO2007120544A2/en not_active Ceased
- 2007-04-04 CA CA2683664A patent/CA2683664C/en not_active Expired - Fee Related
-
2015
- 2015-02-18 US US14/624,854 patent/US20150157589A1/en not_active Abandoned
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003510357A (ja) * | 1999-10-07 | 2003-03-18 | キサンタス ライフ サイエンシズ,インコーポレイテッド | ピルビン酸エステル組成物ならびに虚血および再灌流の事象後の蘇生のための使用法 |
| JP2004528307A (ja) * | 2001-03-15 | 2004-09-16 | ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション | サイトカインにより媒介される炎症性状態の治療のためのピルベートおよび/またはその誘導体の使用方法 |
| JP2005526832A (ja) * | 2002-04-17 | 2005-09-08 | クリティカル セラピューティクス,インコーポレイテッド | α−ケトアルカン酸エステルまたは−アミドおよび乳酸または乳酸塩を含有する医薬組成物 |
| JP2005527592A (ja) * | 2002-04-17 | 2005-09-15 | クリティカル セラピューティクス,インコーポレイテッド | α−ケトアルカン酸または−エステルもしくは−アミドを用いる腸閉塞の処置方法 |
| WO2005002563A2 (en) * | 2003-06-13 | 2005-01-13 | University Of Pittsburgh - Of The Commonwealth System Of Higher Eduction | Method for treating alcoholic hepatitis |
| WO2005044299A1 (en) * | 2003-10-27 | 2005-05-19 | University Of Pennsylvania | Cytoprotective effects of ethyl pyruvate |
| WO2005094236A2 (en) * | 2003-11-07 | 2005-10-13 | Henry M. Jackson Foundation | Activation of hypoxia-inducible gene expression |
Non-Patent Citations (1)
| Title |
|---|
| JPN6012041705; MOSCIANO,G.: 'Organoleptic Characteristics of Flavor Materials' Perfum Flavorist Vol.26, No.4, 2001, P.82,84-85 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101472613A (zh) | 2009-07-01 |
| US20150157589A1 (en) | 2015-06-11 |
| NZ572649A (en) | 2011-03-31 |
| AU2007238938A1 (en) | 2007-10-25 |
| EP2010218A4 (en) | 2010-05-12 |
| CA2683664C (en) | 2015-07-07 |
| AU2007238938B2 (en) | 2013-05-23 |
| WO2007120544A2 (en) | 2007-10-25 |
| WO2007120544A3 (en) | 2007-12-21 |
| EP2010218A2 (en) | 2009-01-07 |
| CA2683664A1 (en) | 2007-10-25 |
| EP2010218B1 (en) | 2018-10-10 |
| US20100047221A1 (en) | 2010-02-25 |
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