JP2009533097A - 吸入器用薬剤マガジン及び多数回投与型粉末吸入器 - Google Patents

吸入器用薬剤マガジン及び多数回投与型粉末吸入器 Download PDF

Info

Publication number
JP2009533097A
JP2009533097A JP2009504546A JP2009504546A JP2009533097A JP 2009533097 A JP2009533097 A JP 2009533097A JP 2009504546 A JP2009504546 A JP 2009504546A JP 2009504546 A JP2009504546 A JP 2009504546A JP 2009533097 A JP2009533097 A JP 2009533097A
Authority
JP
Japan
Prior art keywords
internal structure
drug
foil
magazine according
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009504546A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009533097A5 (https=
Inventor
ヘルベルト ヴァハテル
ヨハネス ゲゼル
ブルークハルト ペー メッツガー
ミハエル シュパレク
ミハエル クリューガー
フーベルト クンツェ
アーヒム モーゼル
エルマー モック
アントニオ ランチ
アンドレ クロップフェンシュタイン
Original Assignee
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング filed Critical ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
Publication of JP2009533097A publication Critical patent/JP2009533097A/ja
Publication of JP2009533097A5 publication Critical patent/JP2009533097A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0061—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using pre-packed dosages having an insert inside
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
JP2009504546A 2006-04-13 2007-04-13 吸入器用薬剤マガジン及び多数回投与型粉末吸入器 Pending JP2009533097A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06405163A EP1844809A1 (de) 2006-04-13 2006-04-13 Medikamentenmagazin für einen Inhalator, sowie Mehrdosispulverinhalator
PCT/CH2007/000180 WO2007118342A2 (de) 2006-04-13 2007-04-13 Medikamentenmagazin für einen inhalator, sowie mehrdosispulverinhalator

Publications (2)

Publication Number Publication Date
JP2009533097A true JP2009533097A (ja) 2009-09-17
JP2009533097A5 JP2009533097A5 (https=) 2010-05-06

Family

ID=36942292

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009504546A Pending JP2009533097A (ja) 2006-04-13 2007-04-13 吸入器用薬剤マガジン及び多数回投与型粉末吸入器

Country Status (5)

Country Link
US (1) US8267082B2 (https=)
EP (2) EP1844809A1 (https=)
JP (1) JP2009533097A (https=)
CA (1) CA2644013C (https=)
WO (1) WO2007118342A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015523157A (ja) * 2012-07-12 2015-08-13 マンカインド コーポレイション 乾燥粉末薬物送達システムおよび方法

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6923175B2 (en) 2002-03-20 2005-08-02 Mannkind Corporation Inhalation apparatus
US7861712B2 (en) 2004-04-23 2011-01-04 Manta Product Development Sealed capsule including an integrated puncturing mechanism
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
KR20130066695A (ko) 2004-08-23 2013-06-20 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
US8763605B2 (en) 2005-07-20 2014-07-01 Manta Devices, Llc Inhalation device
MX373000B (es) 2005-09-14 2020-05-21 Mannkind Corp Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas.
EP1986679B1 (en) 2006-02-22 2017-10-25 MannKind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
US20070214794A1 (en) * 2006-03-15 2007-09-20 Tweeton Erik H Supercharged subsonic rotary ramjet turbine with vibration free piston air compressor
DE102006014434A1 (de) * 2006-03-27 2007-10-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Packmittel für Mehrdosispulverinhalatoren mit optimierten Entleerungseigenschaften
WO2008086413A2 (en) 2007-01-09 2008-07-17 Mystic Pharmaceuticals, Inc. Intranasal cartridge devices
US9248076B2 (en) 2007-05-16 2016-02-02 Mystic Pharmaceuticals, Inc. Dose dispensing containers
EP2170444B1 (en) 2007-07-06 2016-09-07 Manta Devices, LLC Inhalation devices for storing and delivering medicament
US11224704B2 (en) 2007-07-06 2022-01-18 Manta Devices, Llc Dose delivery device for inhalation
GB0800708D0 (en) * 2008-01-16 2008-02-20 Dunne Stephen T Atomising device
CN101827626B (zh) 2008-06-13 2015-03-18 曼金德公司 干粉吸入器和用于药物输送的系统
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2421385T3 (es) 2008-06-20 2013-09-02 Mannkind Corp Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
WO2010021589A1 (en) * 2008-08-20 2010-02-25 Astrazeneca Ab Inhaler
US20110271958A1 (en) * 2008-11-06 2011-11-10 Medispray Laboratories Pvt. Ltd Inhaler device
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
WO2010083042A1 (en) * 2009-01-15 2010-07-22 Manta Devices, Llc Delivery device
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
KR102584844B1 (ko) 2009-06-12 2023-10-04 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
WO2011116293A2 (en) 2010-03-19 2011-09-22 Manta Devices, Llc Delivery device and related methods
CN102985125A (zh) 2010-06-21 2013-03-20 曼金德公司 干粉药物输送系统和方法
SG194034A1 (en) 2011-04-01 2013-11-29 Mannkind Corp Blister package for pharmaceutical cartridges
US8585659B2 (en) * 2011-05-31 2013-11-19 Mystic Pharmaceuticals, Inc. Piercing device for drug delivery systems
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
US11103659B2 (en) 2011-07-06 2021-08-31 Manta Devices, Llc Delivery device and related methods
MX2014004983A (es) 2011-10-24 2014-09-22 Mannkid Corp Metodos y composiciones para tratar dolor.
TW201340893A (zh) * 2011-12-20 2013-10-16 British American Tobacco Co 吸煙物件及其他氣流輸送物件（一）
US9649454B2 (en) 2012-05-03 2017-05-16 Manta Devices, Llc Delivery device and related methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
GB201301192D0 (en) * 2013-01-23 2013-03-06 Vectura Delivery Devices Ltd A blister piercing element for a dry powder inhaler
EP3587404B1 (en) 2013-03-15 2022-07-13 MannKind Corporation Microcrystalline diketopiperazine compositions, methods for preparation and use thereof
MX375448B (es) 2013-07-18 2025-03-06 Mannkind Corp Composiciones farmacéuticas en polvo seco estables al calor y métodos.
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
EP3057627B1 (en) 2013-10-15 2018-07-25 Mystic Pharmaceuticals, Inc. Controllable rate turbulating nozzle
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US11147936B2 (en) 2014-05-02 2021-10-19 Manta Devices, Llc Dose delivery device with cover connected to dose chamber seal
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
JP7376336B2 (ja) * 2019-12-11 2023-11-08 株式会社京都製作所 包装体開封システム
WO2023186758A1 (en) * 2022-03-28 2023-10-05 Astrazeneca Ab Dry powder formulation inhaler and capsule

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004538105A (ja) * 2001-08-16 2004-12-24 メリディカ リミテッド 薬剤収容パックおよび投薬装置

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK172541B1 (da) * 1982-10-08 1998-12-07 Glaxo Group Ltd Apparat til administrering af medikamenter til patienter og en medikamentpakning til brug i apparatet
IT1230313B (it) * 1989-07-07 1991-10-18 Somova Spa Inalatore per medicamenti in capsule.
DK544589D0 (da) * 1989-11-01 1989-11-01 Novo Nordisk As Manuel betjent apparat til dispensering af en forudbestemt maengde af et pulverformet stof
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
EP0528764B1 (en) * 1991-08-16 1996-06-12 Sandoz Ltd. Inhaler for administration of powdery substances
GB9203761D0 (en) * 1992-02-21 1992-04-08 Innovata Biomed Ltd Inhaler
US5896855A (en) * 1992-12-24 1999-04-27 Rhone-Poulenc Rorer Limited Multi dose inhaler apparatus
DE4400083C2 (de) * 1994-01-04 1997-07-03 Asta Medica Ag Verpackung für kleine vordosierte Mengen eines fein verteilten Feststoffs
US5642727A (en) * 1995-07-25 1997-07-01 David Sarnoff Research Center, Inc. Inhaler apparatus using a tribo-electric charging technique
FR2738152B1 (fr) * 1995-09-04 1998-01-23 Tebro Dispositif de pre-dosage de produit pulverulent pour un distributeur de produit
DE19733651A1 (de) 1997-08-04 1999-02-18 Boehringer Ingelheim Pharma Wässrige Aerosolzubereitungen enthaltend biologisch aktive Markomoleküle und Verfahren zur Erzeugung entsprechender Aerosole
AU2509901A (en) * 1999-12-11 2001-06-18 Glaxo Group Limited Medicament dispenser
US20030034271A1 (en) * 2000-01-25 2003-02-20 Burridge Michael D. Internal ejector punch for blister-pack type containers
US6443307B1 (en) * 2000-01-25 2002-09-03 Michael D. Burridge Medication dispenser with an internal ejector
AR028746A1 (es) * 2000-06-23 2003-05-21 Norton Health Care Ltd Cartucho de dosis previamente medidas para inhalador de polvo seco accionado por la respiracion, el inhalador y un metodo de provision de dosis previamente medidas de polvo seco
US6443367B1 (en) * 2000-09-11 2002-09-03 Joseph Bova Deepwatering device
GB0303870D0 (en) 2003-02-20 2003-03-26 Norton Healthcare Ltd Pre-metered dose magazine for breath-actuated dry powder inhaler
GB0315509D0 (en) 2003-07-02 2003-08-06 Meridica Ltd Dispensing device

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004538105A (ja) * 2001-08-16 2004-12-24 メリディカ リミテッド 薬剤収容パックおよび投薬装置

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015523157A (ja) * 2012-07-12 2015-08-13 マンカインド コーポレイション 乾燥粉末薬物送達システムおよび方法

Also Published As

Publication number Publication date
EP1844809A1 (de) 2007-10-17
CA2644013A1 (en) 2007-10-25
EP2004262A2 (de) 2008-12-24
US8267082B2 (en) 2012-09-18
US20090250057A1 (en) 2009-10-08
CA2644013C (en) 2015-03-17
WO2007118342A3 (de) 2008-01-17
WO2007118342A2 (de) 2007-10-25
EP2004262B1 (de) 2019-08-14

Similar Documents

Publication Publication Date Title
JP2009533097A (ja) 吸入器用薬剤マガジン及び多数回投与型粉末吸入器
JP6160642B2 (ja) 粉末吸入器
JP2009533098A (ja) 薬剤送出装置、このための薬剤キャリヤ及び薬剤コンパートメントから薬剤を取り出す方法
JP5976273B2 (ja) 吸入器
JP4995324B2 (ja) 粉末吸入器
JP5233049B2 (ja) 吸入器用マウスピース
EP2066380B1 (de) Inhalator
JP2009533114A (ja) 吸入器
JP2009538656A (ja) アトマイザ
JP2009517148A (ja) 計量投与器具
JP2011512209A (ja) 粉末吸入器
JP2009533113A (ja) 吸入器
KR20080068924A (ko) 흡입용 분말 캡슐 천공용 니들
JP5504156B2 (ja) 吸入器
JP5812354B2 (ja) 吸入器具
JP5154541B2 (ja) 薬剤マガジン、薬剤マガジンの開放装置及び方法、多数回投与型粉末吸入器
KR20080110866A (ko) 방출 특성이 최적화된 다중-투약 분말 흡입기용 패키지 수단
JP2009533191A (ja) 医薬製剤を収容する粉末吸入器用の２部分構成金属カプセル
HK1128892A (en) Packaging means for multi-dose powder inhalers with optimized discharging properties

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100318

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20100318

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20120202

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120206

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120501

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20120806