CA2644013C - Medicament magazine for an inhaler, and a multi-dose powder inhaler - Google Patents

Medicament magazine for an inhaler, and a multi-dose powder inhaler Download PDF

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Publication number
CA2644013C
CA2644013C CA2644013A CA2644013A CA2644013C CA 2644013 C CA2644013 C CA 2644013C CA 2644013 A CA2644013 A CA 2644013A CA 2644013 A CA2644013 A CA 2644013A CA 2644013 C CA2644013 C CA 2644013C
Authority
CA
Canada
Prior art keywords
internal structure
medicament
foil
magazine
cutting edge
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2644013A
Other languages
English (en)
French (fr)
Other versions
CA2644013A1 (en
Inventor
Herbert Wachtel
Johannes Geser
Burkhard P. Metzger
Michael Spallek
Michael Krueger
Hubert Kunze
Achim Moser
Elmar Mock
Antonino Lanci
Andre Klopfenstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Publication of CA2644013A1 publication Critical patent/CA2644013A1/en
Application granted granted Critical
Publication of CA2644013C publication Critical patent/CA2644013C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0061—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using pre-packed dosages having an insert inside
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
CA2644013A 2006-04-13 2007-04-13 Medicament magazine for an inhaler, and a multi-dose powder inhaler Active CA2644013C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06405163.4 2006-04-13
EP06405163A EP1844809A1 (de) 2006-04-13 2006-04-13 Medikamentenmagazin für einen Inhalator, sowie Mehrdosispulverinhalator
PCT/CH2007/000180 WO2007118342A2 (de) 2006-04-13 2007-04-13 Medikamentenmagazin für einen inhalator, sowie mehrdosispulverinhalator

Publications (2)

Publication Number Publication Date
CA2644013A1 CA2644013A1 (en) 2007-10-25
CA2644013C true CA2644013C (en) 2015-03-17

Family

ID=36942292

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2644013A Active CA2644013C (en) 2006-04-13 2007-04-13 Medicament magazine for an inhaler, and a multi-dose powder inhaler

Country Status (5)

Country Link
US (1) US8267082B2 (https=)
EP (2) EP1844809A1 (https=)
JP (1) JP2009533097A (https=)
CA (1) CA2644013C (https=)
WO (1) WO2007118342A2 (https=)

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US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
WO2003080149A2 (en) 2002-03-20 2003-10-02 Mannkind Corporation Inhalation apparatus
US7861712B2 (en) 2004-04-23 2011-01-04 Manta Product Development Sealed capsule including an integrated puncturing mechanism
PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
KR101644250B1 (ko) 2004-08-23 2016-07-29 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
US8763605B2 (en) 2005-07-20 2014-07-01 Manta Devices, Llc Inhalation device
CN104324362B (zh) 2005-09-14 2018-04-24 曼金德公司 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法
IN2015DN00888A (https=) 2006-02-22 2015-07-10 Mannkind Corp
US20070214794A1 (en) * 2006-03-15 2007-09-20 Tweeton Erik H Supercharged subsonic rotary ramjet turbine with vibration free piston air compressor
DE102006014434A1 (de) * 2006-03-27 2007-10-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Packmittel für Mehrdosispulverinhalatoren mit optimierten Entleerungseigenschaften
JP2010515541A (ja) 2007-01-09 2010-05-13 ミスティック ファーマシューティカルズ， インコーポレイテッド 経鼻カートリッジデバイス
US9248076B2 (en) 2007-05-16 2016-02-02 Mystic Pharmaceuticals, Inc. Dose dispensing containers
JP5528336B2 (ja) 2007-07-06 2014-06-25 マンタ デバイシス，エルエルシー デリバリー装置及び関連方法
US11224704B2 (en) 2007-07-06 2022-01-18 Manta Devices, Llc Dose delivery device for inhalation
GB0800708D0 (en) * 2008-01-16 2008-02-20 Dunne Stephen T Atomising device
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
KR101628410B1 (ko) 2008-06-20 2016-06-08 맨카인드 코포레이션 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
WO2010021589A1 (en) * 2008-08-20 2010-02-25 Astrazeneca Ab Inhaler
AU2009312611B2 (en) * 2008-11-06 2014-06-19 Medispray Laboratories Pvt. Ltd Inhaler device
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
WO2010083042A1 (en) * 2009-01-15 2010-07-22 Manta Devices, Llc Delivery device
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
CN104721825B (zh) 2009-06-12 2019-04-12 曼金德公司 具有确定比表面积的二酮哌嗪颗粒
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
WO2011116293A2 (en) 2010-03-19 2011-09-22 Manta Devices, Llc Delivery device and related methods
IL223742A (en) 2010-06-21 2016-06-30 Mannkind Corp A dry powder inhaler and preparation for it
AU2012236150B2 (en) 2011-04-01 2016-03-31 Mannkind Corporation Blister package for pharmaceutical cartridges
US8585659B2 (en) * 2011-05-31 2013-11-19 Mystic Pharmaceuticals, Inc. Piercing device for drug delivery systems
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
US11103659B2 (en) 2011-07-06 2021-08-31 Manta Devices, Llc Delivery device and related methods
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
TW201340893A (zh) * 2011-12-20 2013-10-16 British American Tobacco Co 吸煙物件及其他氣流輸送物件（一）
US9649454B2 (en) 2012-05-03 2017-05-16 Manta Devices, Llc Delivery device and related methods
CN104619369B (zh) 2012-07-12 2018-01-30 曼金德公司 干粉药物输送系统和方法
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
GB201301192D0 (en) * 2013-01-23 2013-03-06 Vectura Delivery Devices Ltd A blister piercing element for a dry powder inhaler
AU2014228415B2 (en) 2013-03-15 2018-08-09 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
MX375448B (es) 2013-07-18 2025-03-06 Mannkind Corp Composiciones farmacéuticas en polvo seco estables al calor y métodos.
US11446127B2 (en) 2013-08-05 2022-09-20 Mannkind Corporation Insufflation apparatus and methods
US10149951B2 (en) 2013-10-15 2018-12-11 Mystic Pharmaceuticals, Inc. Controllable rate turbulating nozzle
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
WO2015168572A2 (en) 2014-05-02 2015-11-05 Manta Devices, Llc Delivery device and related methods
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
JP7376336B2 (ja) * 2019-12-11 2023-11-08 株式会社京都製作所 包装体開封システム
WO2023186758A1 (en) * 2022-03-28 2023-10-05 Astrazeneca Ab Dry powder formulation inhaler and capsule

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IT1230313B (it) * 1989-07-07 1991-10-18 Somova Spa Inalatore per medicamenti in capsule.
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DE69211450T2 (de) * 1991-08-16 1996-12-05 Sandoz Ag Inhalator zur Verabreichung von pulverförmigen Substanzen
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DE4400083C2 (de) * 1994-01-04 1997-07-03 Asta Medica Ag Verpackung für kleine vordosierte Mengen eines fein verteilten Feststoffs
US5642727A (en) * 1995-07-25 1997-07-01 David Sarnoff Research Center, Inc. Inhaler apparatus using a tribo-electric charging technique
FR2738152B1 (fr) * 1995-09-04 1998-01-23 Tebro Dispositif de pre-dosage de produit pulverulent pour un distributeur de produit
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Also Published As

Publication number Publication date
CA2644013A1 (en) 2007-10-25
EP2004262A2 (de) 2008-12-24
EP1844809A1 (de) 2007-10-17
US8267082B2 (en) 2012-09-18
EP2004262B1 (de) 2019-08-14
JP2009533097A (ja) 2009-09-17
US20090250057A1 (en) 2009-10-08
WO2007118342A3 (de) 2008-01-17
WO2007118342A2 (de) 2007-10-25

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