JP2009533065A5 - - Google Patents
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- Publication number
- JP2009533065A5 JP2009533065A5 JP2009505696A JP2009505696A JP2009533065A5 JP 2009533065 A5 JP2009533065 A5 JP 2009533065A5 JP 2009505696 A JP2009505696 A JP 2009505696A JP 2009505696 A JP2009505696 A JP 2009505696A JP 2009533065 A5 JP2009533065 A5 JP 2009533065A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- receptor
- cell
- sweet receptor
- homomeric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 210000004027 cell Anatomy 0.000 claims 30
- 238000000034 method Methods 0.000 claims 22
- 102000005962 receptors Human genes 0.000 claims 18
- 108020003175 receptors Proteins 0.000 claims 18
- 239000003795 chemical substances by application Substances 0.000 claims 16
- 235000009508 confectionery Nutrition 0.000 claims 16
- 108091006027 G proteins Proteins 0.000 claims 10
- 102000030782 GTP binding Human genes 0.000 claims 10
- 108091000058 GTP-Binding Proteins 0.000 claims 10
- XCOJIVIDDFTHGB-UEUZTHOGSA-N Perillartine Chemical compound CC(=C)[C@H]1CCC(\C=N\O)=CC1 XCOJIVIDDFTHGB-UEUZTHOGSA-N 0.000 claims 5
- 210000004962 mammalian cell Anatomy 0.000 claims 5
- 241000840267 Moma Species 0.000 claims 4
- 230000003834 intracellular effect Effects 0.000 claims 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
- 101000659774 Homo sapiens Taste receptor type 1 member 3 Proteins 0.000 claims 3
- 102100035942 Taste receptor type 1 member 3 Human genes 0.000 claims 3
- 229920001184 polypeptide Polymers 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 2
- 241000238631 Hexapoda Species 0.000 claims 2
- 229910052791 calcium Inorganic materials 0.000 claims 2
- 239000011575 calcium Substances 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 210000003527 eukaryotic cell Anatomy 0.000 claims 2
- 230000005714 functional activity Effects 0.000 claims 2
- 239000001963 growth medium Substances 0.000 claims 2
- 244000000013 helminth Species 0.000 claims 2
- 230000011664 signaling Effects 0.000 claims 2
- 125000000020 sulfo group Chemical group O=S(=O)([*])O[H] 0.000 claims 2
- 235000019605 sweet taste sensations Nutrition 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 210000005253 yeast cell Anatomy 0.000 claims 2
- 239000000556 agonist Substances 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 230000000392 somatic effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79368606P | 2006-04-20 | 2006-04-20 | |
| PCT/CH2007/000185 WO2007121599A1 (en) | 2006-04-20 | 2007-04-19 | Functional method to identify tastants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009533065A JP2009533065A (ja) | 2009-09-17 |
| JP2009533065A5 true JP2009533065A5 (enExample) | 2012-07-12 |
Family
ID=38430537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009505696A Ceased JP2009533065A (ja) | 2006-04-20 | 2007-04-19 | 味覚物質同定のための機能的方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8124360B2 (enExample) |
| EP (1) | EP2008095A1 (enExample) |
| JP (1) | JP2009533065A (enExample) |
| KR (1) | KR101356892B1 (enExample) |
| WO (1) | WO2007121599A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7851005B2 (en) | 2005-05-23 | 2010-12-14 | Cadbury Adams Usa Llc | Taste potentiator compositions and beverages containing same |
| US7851006B2 (en) | 2005-05-23 | 2010-12-14 | Cadbury Adams Usa Llc | Taste potentiator compositions and beverages containing same |
| ES2399059T3 (es) | 2005-05-23 | 2013-03-25 | Kraft Foods Global Brands Llc | Composiciones potenciadoras del dulzor |
| MX365710B (es) | 2011-04-29 | 2019-06-11 | Intercontinental Great Brands Llc | Acido encapsulado, metodo para la preparacion del mismo y goma de mascar que comprende el mismo. |
| WO2013072332A1 (en) | 2011-11-14 | 2013-05-23 | Givaudan Sa | Methods of using antagonists of bitter taste receptors |
| US20140147556A1 (en) * | 2012-11-27 | 2014-05-29 | Elwha Llc | Edible or inhalable compositions having antibodies and methods of use |
| JP6755640B2 (ja) | 2014-03-28 | 2020-09-16 | 味の素株式会社 | 甘味受容体キメラタンパク質及びその利用 |
| CN105504036A (zh) * | 2016-02-16 | 2016-04-20 | 齐鲁工业大学 | 一种具有强热稳定性的甜味蛋白monellin突变体及其制备方法 |
| CN112823011A (zh) | 2018-07-09 | 2021-05-18 | 加利福尼亚大学董事会 | 基于t细胞的免疫疗法的基因靶标 |
| CN112102886B (zh) * | 2020-08-14 | 2024-04-26 | 云南中烟工业有限责任公司 | 一种化合物呈味判别方法 |
| KR20240130158A (ko) | 2021-12-03 | 2024-08-28 | 더 브로드 인스티튜트, 인코퍼레이티드 | 효율적인 생체내 전달을 위한 조성물 및 방법 |
| JP2025519070A (ja) | 2022-05-17 | 2025-06-24 | エンヴェロップ セラピューティクス， インコーポレイテッド | 効率的ｉｎ ｖｉｖｏ送達のための組成物および方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5825980B2 (ja) * | 1976-02-12 | 1983-05-31 | ヤマサ醤油株式会社 | サイクリックヌクレオチドの定量法 |
| WO1990005745A1 (en) * | 1988-11-18 | 1990-05-31 | The General Hospital Corporation | A cAMP-RESPONSIVE TRANSCRIPTIONAL ENHANCER BINDING PROTEIN |
| US5462856A (en) | 1990-07-19 | 1995-10-31 | Bunsen Rush Laboratories, Inc. | Methods for identifying chemicals that act as agonists or antagonists for receptors and other proteins involved in signal transduction via pathways that utilize G-proteins |
| US5401629A (en) * | 1990-08-07 | 1995-03-28 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Assay methods and compositions useful for measuring the transduction of an intracellular signal |
| WO2001018050A2 (en) | 1999-09-10 | 2001-03-15 | The Regents Of The University Of California | T2r taste receptor family |
| TW201022287A (en) | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
| US6955887B2 (en) * | 2001-03-30 | 2005-10-18 | Senomyx, Inc. | Use of T1R hetero-oligomeric taste receptor to screen for compounds that modulate taste signaling |
| WO2004055048A2 (en) | 2002-12-18 | 2004-07-01 | Givaudan Sa | Chimeric alpha q-gustducin g-proteins |
| WO2004069191A2 (en) * | 2003-02-03 | 2004-08-19 | Senomyx Inc. | Identification of t1r and t2r modulators |
| NZ619746A (en) | 2003-08-06 | 2014-05-30 | Senomyx Inc | Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof |
-
2007
- 2007-04-19 JP JP2009505696A patent/JP2009533065A/ja not_active Ceased
- 2007-04-19 KR KR1020087025402A patent/KR101356892B1/ko active Active
- 2007-04-19 EP EP07720082A patent/EP2008095A1/en not_active Withdrawn
- 2007-04-19 WO PCT/CH2007/000185 patent/WO2007121599A1/en not_active Ceased
- 2007-04-19 US US12/297,695 patent/US8124360B2/en not_active Expired - Fee Related
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