JP2009533020A5 - - Google Patents
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- JP2009533020A5 JP2009533020A5 JP2009502208A JP2009502208A JP2009533020A5 JP 2009533020 A5 JP2009533020 A5 JP 2009533020A5 JP 2009502208 A JP2009502208 A JP 2009502208A JP 2009502208 A JP2009502208 A JP 2009502208A JP 2009533020 A5 JP2009533020 A5 JP 2009533020A5
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- Japan
- Prior art keywords
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- structural element
- binding structural
- amino acid
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78656906P | 2006-03-27 | 2006-03-27 | |
| US60/786,569 | 2006-03-27 | ||
| PCT/GB2007/001108 WO2007110631A1 (en) | 2006-03-27 | 2007-03-27 | Binding member for gm-csf receptor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013002623A Division JP5665894B2 (ja) | 2006-03-27 | 2013-01-10 | Gm−csf受容体に対する結合構造要素 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009533020A JP2009533020A (ja) | 2009-09-17 |
| JP2009533020A5 true JP2009533020A5 (https=) | 2010-05-13 |
| JP5335662B2 JP5335662B2 (ja) | 2013-11-06 |
Family
ID=38293698
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009502208A Active JP5335662B2 (ja) | 2006-03-27 | 2007-03-27 | Gm−csf受容体に対する結合構造要素 |
| JP2013002623A Active JP5665894B2 (ja) | 2006-03-27 | 2013-01-10 | Gm−csf受容体に対する結合構造要素 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013002623A Active JP5665894B2 (ja) | 2006-03-27 | 2013-01-10 | Gm−csf受容体に対する結合構造要素 |
Country Status (15)
| Country | Link |
|---|---|
| US (8) | US8263075B2 (https=) |
| EP (3) | EP1999152B1 (https=) |
| JP (2) | JP5335662B2 (https=) |
| KR (2) | KR101451546B1 (https=) |
| CN (3) | CN101443360B (https=) |
| BR (1) | BRPI0709259B1 (https=) |
| CA (1) | CA2647449C (https=) |
| DK (3) | DK2423229T3 (https=) |
| ES (3) | ES2424467T3 (https=) |
| MX (2) | MX348827B (https=) |
| PL (3) | PL1999152T3 (https=) |
| PT (3) | PT2423230E (https=) |
| RU (2) | RU2495050C2 (https=) |
| SI (3) | SI1999152T1 (https=) |
| WO (1) | WO2007110631A1 (https=) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2527590B2 (ja) | 1988-02-17 | 1996-08-28 | 三洋電機株式会社 | 空冷式吸収冷凍機 |
| PL1999152T3 (pl) * | 2006-03-27 | 2013-05-31 | Medimmune Ltd | Element wiążący receptor GM-CSF |
| US20080206241A1 (en) | 2006-11-21 | 2008-08-28 | Kalobios Pharmaceuticals Inc. | Methods of Treating Chronic Inflammatory Diseases Using a GM-CSF Antagonist |
| US8075885B2 (en) | 2008-04-07 | 2011-12-13 | Kalobios Pharmaceuticals, Inc. | Methods of treating heart failure using an anti-GM-CSF antibody |
| AU2015224416B2 (en) * | 2008-12-22 | 2017-04-20 | The University Of Melbourne | Osteoarthritis treatment |
| RU2630969C2 (ru) | 2008-12-22 | 2017-09-15 | Де Юниверсити Оф Мельбурн | Лечение боли |
| EP3056217B1 (en) * | 2008-12-22 | 2021-06-30 | The University of Melbourne | Osteoarthritis treatment |
| CN102459340A (zh) * | 2009-04-23 | 2012-05-16 | 特罗科隆科学有限公司 | 粒性白血细胞-巨噬细胞菌落-刺激因子(gm-csf)中和抗体 |
| WO2010128035A1 (en) * | 2009-05-05 | 2010-11-11 | Morphosys Ag | Treatment for multiple sclerosis |
| WO2011028697A2 (en) * | 2009-09-03 | 2011-03-10 | The Regents Of The University Of Colorado, A Body Corporate | Uses of cd 116 expression level |
| EP2766394B1 (en) * | 2011-10-10 | 2017-11-22 | Medimmune Limited | Treatment for rheumatoid arthritis |
| JP6426001B2 (ja) * | 2011-11-17 | 2018-11-21 | グリア エスピー ゼット.オー.オー. | 神経膠腫を治療するための組成物および方法 |
| EP2602264A1 (en) | 2011-12-05 | 2013-06-12 | Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka mbH | GDF-5 mutant for inducing cartilage formation |
| WO2013090989A1 (en) | 2011-12-22 | 2013-06-27 | Csl Limited | Method of treating inflammatory bowel disease |
| AR093297A1 (es) | 2012-10-31 | 2015-05-27 | Amgen Res Munich Gmbh | Formulacion liquida que comprende un compuesto neutralizante de gm-csf |
| EP2914289B1 (en) | 2012-10-31 | 2019-05-22 | Takeda GmbH | Lyophilized formulation comprising gm-csf neutralizing compound |
| SI2932264T1 (sl) | 2012-12-14 | 2019-05-31 | Biontech Rna Pharmaceuticals Gmbh | Novi MHC-neodvisni, s tumorjem povezani antigeni |
| CN103193882B (zh) * | 2013-03-29 | 2014-11-05 | 浙江大学 | 胚胎干细胞特异性标志物GM-CSFRα及其应用 |
| US10745475B2 (en) | 2013-08-30 | 2020-08-18 | Takeda Gmbh | Antibodies neutralizing GM-CSF for use in the treatment of rheumatoid arthritis or as analgesics |
| EP3139960B1 (en) | 2014-05-07 | 2024-01-17 | Takeda Pharmaceutical Company Limited | Liquid formulation comprising gm-csf neutralizing compound |
| EP3145541A1 (en) * | 2014-05-19 | 2017-03-29 | Medimmune Limited | Treatment for rheumatoid arthritis |
| GB201503139D0 (en) * | 2015-02-25 | 2015-04-08 | Univ Leicester | Diagnostic and therapeutic target |
| GB201519331D0 (en) * | 2015-11-02 | 2015-12-16 | Glaxosmithkline Ip Dev Ltd | Treatment paradigm |
| AU2017270027B2 (en) | 2016-05-24 | 2024-07-11 | Medimmune Limited | Anti-PAD4 autoantibodies as clinical response biomarkers for the treatment of rheumatoid arthritis |
| BR112019018022A2 (pt) | 2017-03-01 | 2020-06-02 | Medimmune Limited | Formulações de anticorpos monoclonais |
| EP3623382A1 (en) | 2018-09-14 | 2020-03-18 | Universität Zürich | Ligands to gm-csf or gm-csf-receptor for use in leukemia in a patient having undergone allo-hct |
| US11655293B2 (en) * | 2018-02-22 | 2023-05-23 | Universitat Zurich | Ligands to GM-CSF or GM-CSF-receptor for use in leukemia in a patient having undergone allo-HCT |
| US11078264B2 (en) | 2018-10-17 | 2021-08-03 | University Of Connecticut | Inhibiting granulocyte macrophage-colony stimulating factor (GM-CSF) prevents preterm birth |
| WO2020096664A1 (en) | 2018-11-09 | 2020-05-14 | Kiniksa Pharmaceuticals, Ltd. | Treatment for giant cell arteritis |
| US20220010007A1 (en) | 2018-11-09 | 2022-01-13 | Kiniksa Pharmaeuticals, Ltd. | Treatment for Giant Cell Arteritis |
| WO2020108423A1 (en) * | 2018-11-27 | 2020-06-04 | Staidson (Beijing) Biopharmaceuticals Co., Ltd. | Antibodies specifically recognizing granulocyte-macrophage colony stimulating factor receptor alpha and uses thereof |
| CN118949031A (zh) | 2019-06-03 | 2024-11-15 | 基尼克萨制药股份有限公司 | 用gm-csf拮抗剂治疗癌症 |
| US20230030680A1 (en) * | 2020-01-07 | 2023-02-02 | St. Jude Children's Research Hospital, Inc | Chimeric gmcsf-il18 receptor |
| US20210284744A1 (en) | 2020-03-15 | 2021-09-16 | Kiniksa Pharmaceuticals, Ltd. | Treatment of cytokine release syndrome with gm-csf antagonists |
| WO2021204649A1 (en) | 2020-04-06 | 2021-10-14 | Glaxosmithkline Intellectual Property Development Limited | Gm-csf antagonists for use in the treatment of severe pulmonary covid-19, cytokine release syndrome and/or acute respiratory distress syndrome |
| CN111690063A (zh) * | 2020-05-25 | 2020-09-22 | 北京大学 | 一种抗gm-csf纳米抗体及其制备方法和应用 |
| JP2023546657A (ja) * | 2020-10-26 | 2023-11-07 | キニクサ ファーマシューティカルズ, リミテッド | Gm-csf拮抗薬を用いたがんの治療 |
| JP2024500747A (ja) | 2020-12-18 | 2024-01-10 | キニクサ ファーマシューティカルズ, リミテッド | タンパク質組成物ならびにそれを産生及び使用するための方法 |
| CN116887856A (zh) * | 2022-01-20 | 2023-10-13 | 舒泰神(北京)生物制药股份有限公司 | 一种特异性地识别粒细胞-巨噬细胞集落刺激因子受体的抗体制剂及其应用 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| WO1991002063A1 (en) * | 1989-08-11 | 1991-02-21 | Amrad Corporation Limited | Improvements in granulocyte-macrophage colony-stimulating factor receptor and derivatives thereof |
| US5629283A (en) * | 1989-08-11 | 1997-05-13 | Amrad Corporation Limited | Granulocyte-macrophage colony-stimulating factor receptor and derivatives thereof |
| GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| WO1994009149A1 (en) | 1990-08-10 | 1994-04-28 | Amrad Corporation Limited | Monoclonal antibody |
| ES2136092T3 (es) | 1991-09-23 | 1999-11-16 | Medical Res Council | Procedimientos para la produccion de anticuerpos humanizados. |
| GB9203459D0 (en) | 1992-02-19 | 1992-04-08 | Scotgen Ltd | Antibodies with germ-line variable regions |
| US5639641A (en) | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
| CA2149881A1 (en) * | 1992-11-19 | 1994-05-26 | Paul T. Jubinsky | Antibodies for gm-csf receptor and uses thereof |
| ATE199392T1 (de) | 1992-12-04 | 2001-03-15 | Medical Res Council | Multivalente und multispezifische bindungsproteine, deren herstellung und verwendung |
| AUPN780096A0 (en) * | 1996-01-30 | 1996-02-22 | Medvet Science Pty. Ltd. | Cytokine antagonists and agonists |
| DE69941267D1 (de) | 1998-12-10 | 2009-09-24 | Bristol Myers Squibb Co | Proteingerüste für antikörper-nachahmer und andere bindende proteine |
| BRPI0108923B8 (pt) | 2000-03-03 | 2021-05-25 | Cambridge Antibody Tech Limited | elemento de ligação específico, ácido nucleico isolado, célula hospedeira, métodos para produzir um elemento de ligação específico ou domínio vh ou vl de anticorpo, e, para obter um elemento de ligação específico que liga eotaxina |
| US7108852B2 (en) * | 2000-03-20 | 2006-09-19 | Warner-Lambert Company Llc | Methods of treating inflammation using antibodies to M-CSF |
| MXPA05000511A (es) | 2001-07-12 | 2005-09-30 | Jefferson Foote | Anticuepros super humanizados. |
| KR100453877B1 (ko) * | 2001-07-26 | 2004-10-20 | 메덱스젠 주식회사 | 연쇄체화에 의한 면역 글로블린 융합 단백질의 제조 방법 및 이 방법에 의해 제조된 TNFR/Fc 융합 단백질, 상기 단백질을 코딩하는 DNA, 상기 DNA를 포함하는벡터, 및 상기 벡터에 의한 형질전환체 |
| US7282567B2 (en) * | 2002-06-14 | 2007-10-16 | Immunomedics, Inc. | Monoclonal antibody hPAM4 |
| CN100432105C (zh) * | 2002-12-17 | 2008-11-12 | 默克专利有限公司 | 与gd2结合的小鼠14.18抗体的人源化抗体(h14.18)以及其与il-2的融合 |
| US20040146486A1 (en) * | 2003-01-24 | 2004-07-29 | Juan Sun | Hybrid vector system for use as a vaccine |
| PL1999152T3 (pl) * | 2006-03-27 | 2013-05-31 | Medimmune Ltd | Element wiążący receptor GM-CSF |
| US9209965B2 (en) | 2014-01-14 | 2015-12-08 | Microsemi Semiconductor Ulc | Network interface with clock recovery module on line card |
-
2007
- 2007-03-27 PL PL07712963T patent/PL1999152T3/pl unknown
- 2007-03-27 US US11/692,008 patent/US8263075B2/en active Active
- 2007-03-27 KR KR1020137029959A patent/KR101451546B1/ko active Active
- 2007-03-27 US US12/294,616 patent/US8506960B2/en active Active
- 2007-03-27 PT PT111679239T patent/PT2423230E/pt unknown
- 2007-03-27 EP EP07712963A patent/EP1999152B1/en active Active
- 2007-03-27 PL PL11167912T patent/PL2423229T3/pl unknown
- 2007-03-27 JP JP2009502208A patent/JP5335662B2/ja active Active
- 2007-03-27 PT PT77129633T patent/PT1999152E/pt unknown
- 2007-03-27 MX MX2015007466A patent/MX348827B/es unknown
- 2007-03-27 CA CA2647449A patent/CA2647449C/en active Active
- 2007-03-27 SI SI200731100T patent/SI1999152T1/sl unknown
- 2007-03-27 PL PL11167923T patent/PL2423230T3/pl unknown
- 2007-03-27 ES ES11167912T patent/ES2424467T3/es active Active
- 2007-03-27 DK DK11167912.2T patent/DK2423229T3/da active
- 2007-03-27 DK DK11167923.9T patent/DK2423230T3/da active
- 2007-03-27 CN CN2007800154169A patent/CN101443360B/zh not_active Expired - Fee Related
- 2007-03-27 PT PT111679122T patent/PT2423229E/pt unknown
- 2007-03-27 EP EP11167912.2A patent/EP2423229B1/en active Active
- 2007-03-27 ES ES11167923T patent/ES2424468T3/es active Active
- 2007-03-27 SI SI200731286T patent/SI2423230T1/sl unknown
- 2007-03-27 EP EP11167923.9A patent/EP2423230B1/en active Active
- 2007-03-27 SI SI200731285T patent/SI2423229T1/sl unknown
- 2007-03-27 MX MX2008012291A patent/MX2008012291A/es active IP Right Grant
- 2007-03-27 DK DK07712963.3T patent/DK1999152T3/da active
- 2007-03-27 KR KR20087026232A patent/KR101481844B1/ko active Active
- 2007-03-27 BR BRPI0709259-8A patent/BRPI0709259B1/pt not_active IP Right Cessation
- 2007-03-27 ES ES07712963T patent/ES2395839T3/es active Active
- 2007-03-27 WO PCT/GB2007/001108 patent/WO2007110631A1/en not_active Ceased
- 2007-03-27 RU RU2008137763/10A patent/RU2495050C2/ru active
- 2007-03-27 CN CN201310558011.7A patent/CN103641915B/zh not_active Expired - Fee Related
- 2007-03-27 CN CN201310562197.3A patent/CN103641916A/zh active Pending
-
2012
- 2012-12-26 RU RU2012157042A patent/RU2639546C2/ru active
-
2013
- 2013-01-10 JP JP2013002623A patent/JP5665894B2/ja active Active
- 2013-07-12 US US13/941,409 patent/US9085628B2/en active Active
-
2015
- 2015-06-29 US US14/753,792 patent/US20150376285A1/en not_active Abandoned
-
2018
- 2018-05-15 US US15/980,664 patent/US20190040145A1/en not_active Abandoned
-
2019
- 2019-01-08 US US16/242,850 patent/US20190309077A1/en not_active Abandoned
-
2020
- 2020-10-14 US US17/070,623 patent/US20210147559A1/en not_active Abandoned
-
2023
- 2023-10-31 US US18/499,051 patent/US20240124596A1/en active Pending
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