JP2009531463A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009531463A5 JP2009531463A5 JP2009503253A JP2009503253A JP2009531463A5 JP 2009531463 A5 JP2009531463 A5 JP 2009531463A5 JP 2009503253 A JP2009503253 A JP 2009503253A JP 2009503253 A JP2009503253 A JP 2009503253A JP 2009531463 A5 JP2009531463 A5 JP 2009531463A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- tumor
- cell group
- percentage
- lymphoid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 38
- 206010028980 Neoplasm Diseases 0.000 claims 17
- 102100024222 B-lymphocyte antigen CD19 Human genes 0.000 claims 10
- 101000980825 Homo sapiens B-lymphocyte antigen CD19 Proteins 0.000 claims 10
- 102100022297 Integrin alpha-X Human genes 0.000 claims 10
- 210000004443 dendritic cell Anatomy 0.000 claims 10
- 239000005557 antagonist Substances 0.000 claims 8
- 239000003814 drug Substances 0.000 claims 7
- 229940124597 therapeutic agent Drugs 0.000 claims 7
- 238000000034 method Methods 0.000 claims 6
- 101001046686 Homo sapiens Integrin alpha-M Proteins 0.000 claims 5
- 101000800116 Homo sapiens Thy-1 membrane glycoprotein Proteins 0.000 claims 5
- 102100022338 Integrin alpha-M Human genes 0.000 claims 5
- 102100033523 Thy-1 membrane glycoprotein Human genes 0.000 claims 5
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims 5
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 5
- 210000000952 spleen Anatomy 0.000 claims 4
- 239000002246 antineoplastic agent Substances 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 229940127089 cytotoxic agent Drugs 0.000 claims 2
- 210000000066 myeloid cell Anatomy 0.000 claims 2
- 108700012434 CCL3 Proteins 0.000 claims 1
- 229940078811 CD11b antagonist Drugs 0.000 claims 1
- 229940104228 CD18 antagonist Drugs 0.000 claims 1
- 102000000013 Chemokine CCL3 Human genes 0.000 claims 1
- 229940122858 Elastase inhibitor Drugs 0.000 claims 1
- 229940123313 MCP-1 antagonist Drugs 0.000 claims 1
- 210000001185 bone marrow Anatomy 0.000 claims 1
- 239000003638 chemical reducing agent Substances 0.000 claims 1
- 230000002435 cytoreductive effect Effects 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 238000002405 diagnostic procedure Methods 0.000 claims 1
- 239000003602 elastase inhibitor Substances 0.000 claims 1
- SDUQYLNIPVEERB-QPPQHZFASA-N gemcitabine Chemical compound O=C1N=C(N)C=CN1[C@H]1C(F)(F)[C@H](O)[C@@H](CO)O1 SDUQYLNIPVEERB-QPPQHZFASA-N 0.000 claims 1
- 229960005277 gemcitabine Drugs 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000002792 vascular Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78772006P | 2006-03-29 | 2006-03-29 | |
| PCT/US2007/065377 WO2007115045A2 (en) | 2006-03-29 | 2007-03-28 | Diagnostics and treatments for tumors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009531463A JP2009531463A (ja) | 2009-09-03 |
| JP2009531463A5 true JP2009531463A5 (https=) | 2010-05-20 |
Family
ID=38564192
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009503253A Pending JP2009531463A (ja) | 2006-03-29 | 2007-03-28 | 腫瘍の診断と治療 |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20070264193A1 (https=) |
| EP (1) | EP1999151A2 (https=) |
| JP (1) | JP2009531463A (https=) |
| KR (1) | KR20080106946A (https=) |
| CN (1) | CN101448856A (https=) |
| AR (1) | AR060228A1 (https=) |
| AU (1) | AU2007233237A1 (https=) |
| BR (1) | BRPI0709425A2 (https=) |
| CA (1) | CA2647430A1 (https=) |
| CL (1) | CL2007000876A1 (https=) |
| CR (1) | CR10325A (https=) |
| IL (1) | IL193842A0 (https=) |
| MA (1) | MA30348B1 (https=) |
| MX (1) | MX2008012279A (https=) |
| NO (1) | NO20084546L (https=) |
| RU (1) | RU2008142775A (https=) |
| TW (1) | TW200806322A (https=) |
| WO (1) | WO2007115045A2 (https=) |
| ZA (1) | ZA200807590B (https=) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10254601A1 (de) | 2002-11-22 | 2004-06-03 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| DE102004024617A1 (de) | 2004-05-18 | 2005-12-29 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| US20100196509A1 (en) | 2005-02-28 | 2010-08-05 | Jonathan Braun | Methods for Diagnosis and Treatment of Endometrial Cancer |
| US8318906B2 (en) | 2005-04-15 | 2012-11-27 | The Regents Of The University Of California | EMP2 antibodies and their therapeutic uses |
| EP1790664A1 (en) | 2005-11-24 | 2007-05-30 | Ganymed Pharmaceuticals AG | Monoclonal antibodies against claudin-18 for treatment of cancer |
| EP2121757A2 (en) * | 2007-02-21 | 2009-11-25 | Ablynx N.V. | Amino acid sequences directed against vascular endothelial growth factor and polypeptides comprising the same for the treatment of conditions and diseases characterized by excessive and/or pathological angiogenesis or neovascularization |
| WO2011063161A2 (en) | 2009-11-20 | 2011-05-26 | The Regents Of The University Of California | Epithelial membrane protein-2 (emp2) and proliferative vitreoretinopathy (pvr) |
| EP3115469B1 (en) * | 2007-11-19 | 2020-04-29 | Celera Corporation | Lung cancer markers and uses thereof |
| WO2009075768A2 (en) * | 2007-12-07 | 2009-06-18 | Children's Hospital Of Orange County | Optical device and method for real-time chemosensitivity testing |
| EP2262494A2 (en) * | 2008-02-29 | 2010-12-22 | The Board Of Trustees Of The Leland Stanford Junior University | Inhibition of post-radiation tumor growth by an inhibitor of vasculogenesis |
| WO2010017083A1 (en) * | 2008-08-04 | 2010-02-11 | Wayne State University | Methods of treating cancer with cd11b antibodies |
| CN102137939A (zh) * | 2008-08-29 | 2011-07-27 | 霍夫曼-拉罗奇有限公司 | 不依赖vegf的肿瘤的诊断和治疗 |
| WO2010046889A1 (en) * | 2008-10-23 | 2010-04-29 | Quark Pharmaceuticals, Inc. | Methods for delivery of sirna to bone marrow cells and uses thereof |
| US9498431B2 (en) | 2008-12-10 | 2016-11-22 | Jianjian Xu | Controlled releasing composition |
| BRPI0918211A2 (pt) * | 2008-12-23 | 2015-12-08 | Genentech Inc | métodos de identificação de um paciente, métodos de predição da responsividade de um paciente, métodos de monitoramento, métodos de otimização da eficácia terapêutica e kit para detecção do níveis de expressão de p1gf |
| US7615353B1 (en) | 2009-07-06 | 2009-11-10 | Aveo Pharmaceuticals, Inc. | Tivozanib response prediction |
| NZ597531A (en) * | 2009-07-31 | 2014-05-30 | Genentech Inc | Inhibition of tumor metastasis using bv8- or g-csf-antagonists |
| EP2464744A1 (en) * | 2009-08-14 | 2012-06-20 | F. Hoffmann-La Roche AG | Biological markers for monitoring patient response to vegf antagonists |
| US7736861B1 (en) | 2009-10-19 | 2010-06-15 | Aveo Pharmaceuticals, Inc. | Tivozanib response prediction |
| EP2536432B1 (en) * | 2010-02-19 | 2018-08-08 | Cornell University | Method to treat autoimmune demyelinating diseases and other autoimmune or inflammatory diseases |
| JP5852968B2 (ja) * | 2010-02-19 | 2016-02-03 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 上皮膜タンパク質２（ｅｍｐ２）結合試薬および眼疾患治療におけるその使用 |
| KR101313184B1 (ko) * | 2010-06-24 | 2013-09-30 | 한국표준과학연구원 | 질병 지표 검출 키트 및 질병 지표 검출 방법 |
| KR20140068877A (ko) * | 2011-08-17 | 2014-06-09 | 제넨테크, 인크. | 불응성 종양에서의 혈관신생의 억제 |
| WO2013167153A1 (en) | 2012-05-09 | 2013-11-14 | Ganymed Pharmaceuticals Ag | Antibodies useful in cancer diagnosis |
| RU2502471C9 (ru) * | 2012-08-21 | 2015-04-20 | Федеральное бюджетное учреждение науки "Федеральный научный центр медико-профилактических технологий управления рисками здоровью населения" (ФБУН "ФНЦ медико-профилактических технологий управления рисками здоровью населения") | Способ оценки соответствия размеров селезенки норме или отклонению от нее у детей методом ультразвуковой диагностики |
| EP2741086A1 (en) * | 2012-12-06 | 2014-06-11 | Ludwig Boltzmann Gesellschaft | Method for measuring coagulation of blood samples using viscoelastic tests (VET) |
| WO2014127785A1 (en) * | 2013-02-20 | 2014-08-28 | Ganymed Pharmaceuticals Ag | Combination therapy involving antibodies against claudin 18.2 for treatment of cancer |
| US20160030558A1 (en) * | 2013-03-13 | 2016-02-04 | Health Research, Inc. | Enhancement of vaccines |
| RU2546105C1 (ru) * | 2014-04-29 | 2015-04-10 | Федеральное бюджетное учреждение науки "Федеральный научный центр медико-профилактических технологий управления рисками здоровью населения" (ФБУН "ФНЦ медико-профилактических технологий управления рисками здоровью населения") | Способ оценки методом ультразвуковой диагностики соответствия размеров селезенки норме или отклонению от нее у детей от 3 до 15 лет |
| WO2018078158A1 (en) * | 2016-10-31 | 2018-05-03 | Hexal Ag | Antibody preparation |
| EP3826683A4 (en) * | 2018-07-24 | 2022-04-13 | So Young Life Sciences Corporation | USE OF LIPOSOMES TO DELIVERY TO A LIVING CELL A PROTEIN AND A GENE ENCODING THE PROTEIN |
| US20200347449A1 (en) * | 2019-05-01 | 2020-11-05 | The Broad Institute, Inc. | Methods for determining spatial and temporal gene expression dynamics during adult neurogenesis in single cells |
| CN112946291A (zh) * | 2019-12-10 | 2021-06-11 | 上海交通大学医学院附属仁济医院 | Fgf18在制备诊断和预测卵巢癌试剂中的应用及fgf18化学发光检测试剂盒 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4840793A (en) * | 1987-06-11 | 1989-06-20 | Dana-Farber Cancer Institute | Method of reducing tissue damage at an inflammatory site using a monoclonal antibody |
| US20030206899A1 (en) * | 1991-03-29 | 2003-11-06 | Genentech, Inc. | Vascular endothelial cell growth factor antagonists |
| US20020032313A1 (en) * | 1991-03-29 | 2002-03-14 | Genentech, Inc. | Vascular endothelial cell growth factor antagonists |
| US6582959B2 (en) * | 1991-03-29 | 2003-06-24 | Genentech, Inc. | Antibodies to vascular endothelial cell growth factor |
| WO1994004679A1 (en) * | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| DE4422551C1 (de) * | 1994-06-28 | 1995-07-27 | Daimler Benz Ag | Durch Servomotor unterstützte Zahnstangenlenkung |
| US5871697A (en) * | 1995-10-24 | 1999-02-16 | Curagen Corporation | Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing |
| KR100816621B1 (ko) * | 1997-04-07 | 2008-03-24 | 제넨테크, 인크. | 항-ｖｅｇｆ 항체 |
| US20020032315A1 (en) * | 1997-08-06 | 2002-03-14 | Manuel Baca | Anti-vegf antibodies |
| US6884879B1 (en) * | 1997-04-07 | 2005-04-26 | Genentech, Inc. | Anti-VEGF antibodies |
| EP1187633A4 (en) * | 1999-04-08 | 2005-05-11 | Arch Dev Corp | USE OF ANTI-VEGF ANTIBODIES TO ENHANCE RADIATION IN ANTICANCER THERAPY |
| US6703020B1 (en) * | 1999-04-28 | 2004-03-09 | Board Of Regents, The University Of Texas System | Antibody conjugate methods for selectively inhibiting VEGF |
| AU784231B2 (en) * | 2000-06-23 | 2006-02-23 | Schering Aktiengesellschaft | Combinations and compositions which interfere with VEGF/VEGF and angiopoietin/tie receptor function and their use (II) |
| AU2003215163A1 (en) * | 2002-02-12 | 2003-09-04 | Vanderbilt University | Inhibition of vegf receptor signaling reverses tumor resistance to radiotherapy |
| UA101945C2 (uk) * | 2003-05-30 | 2013-05-27 | Дженентек, Инк. | Лікування злоякісного новоутворення за допомогою бевацизумабу |
| WO2005044853A2 (en) * | 2003-11-01 | 2005-05-19 | Genentech, Inc. | Anti-vegf antibodies |
| US20060009360A1 (en) * | 2004-06-25 | 2006-01-12 | Robert Pifer | New adjuvant composition |
-
2007
- 2007-03-28 AU AU2007233237A patent/AU2007233237A1/en not_active Abandoned
- 2007-03-28 MX MX2008012279A patent/MX2008012279A/es active IP Right Grant
- 2007-03-28 CN CNA2007800184412A patent/CN101448856A/zh active Pending
- 2007-03-28 KR KR1020087023600A patent/KR20080106946A/ko not_active Withdrawn
- 2007-03-28 WO PCT/US2007/065377 patent/WO2007115045A2/en not_active Ceased
- 2007-03-28 JP JP2009503253A patent/JP2009531463A/ja active Pending
- 2007-03-28 EP EP07759590A patent/EP1999151A2/en not_active Withdrawn
- 2007-03-28 ZA ZA200807590A patent/ZA200807590B/xx unknown
- 2007-03-28 BR BRPI0709425-6A patent/BRPI0709425A2/pt not_active IP Right Cessation
- 2007-03-28 RU RU2008142775/14A patent/RU2008142775A/ru not_active Application Discontinuation
- 2007-03-28 US US11/692,681 patent/US20070264193A1/en not_active Abandoned
- 2007-03-28 CA CA002647430A patent/CA2647430A1/en not_active Abandoned
- 2007-03-29 TW TW096111126A patent/TW200806322A/zh unknown
- 2007-03-29 CL CL200700876A patent/CL2007000876A1/es unknown
- 2007-03-29 AR ARP070101340A patent/AR060228A1/es not_active Application Discontinuation
-
2008
- 2008-09-02 IL IL193842A patent/IL193842A0/en unknown
- 2008-09-29 CR CR10325A patent/CR10325A/es not_active Application Discontinuation
- 2008-10-20 MA MA31315A patent/MA30348B1/fr unknown
- 2008-10-28 NO NO20084546A patent/NO20084546L/no not_active Application Discontinuation
-
2010
- 2010-04-28 US US12/769,004 patent/US20100239568A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2009531463A5 (https=) | ||
| RU2008142775A (ru) | Диагностика и лечение опухолей | |
| US10363252B2 (en) | Treatment of prostate cancer using hedgehog pathway inhibitors | |
| Lee et al. | Prospective early response imaging biomarker for neoadjuvant breast cancer chemotherapy | |
| Qiu et al. | Circulating tumor cells correlate with clinicopathological features and outcomes in differentiated thyroid cancer | |
| Pan et al. | A simple and sensitive method for exosome detection based on steric hindrance-controlled signal amplification | |
| CA2711843A1 (en) | Her-2 diagnostic methods | |
| Migliorini et al. | Serum and urinary levels of IL-18 and its inhibitor IL-18BP in systemic lupus erythematosus | |
| CA2554776A1 (en) | Test strip composition and method to measure cholesterol from low density lipoproteins | |
| Song et al. | Advancements in noninvasive techniques for transplant rejection: from biomarker detection to molecular imaging | |
| WO2010031749A9 (en) | Compositions and methods for detecting tlr3 | |
| WO2021238086A1 (zh) | 构建体外检测肺癌的数学模型的方法和应用 | |
| JP2013527437A5 (https=) | ||
| WO2010099137A3 (en) | In situ methods for monitoring the emt status of tumor cells in vivo | |
| CN103193746B (zh) | 一类儿茶酚-o-甲基转移酶的特异性探针底物及其应用 | |
| CA2798181A1 (en) | Combination therapy and method for assessing resistance to treatment | |
| JP2012523573A5 (https=) | ||
| Ni et al. | Quantitative analysis of the expression of p53 gene in colorectal carcinoma by using real-time PCR | |
| Kiyono et al. | Evaluation of radioiodinated (2S, αS)-2-(α-(2-iodophenoxy) benzyl) morpholine as a radioligand for imaging of norepinephrine transporter in the heart | |
| Zhao et al. | POS-224 The ratio of neutrophils to lymphocytes effectively predicts glucocorticoid response in idiopathic membranous nephropathy | |
| JP2012127879A (ja) | 腎症の進行度の判定方法並びに線維化抑制剤。 | |
| JP2025524379A (ja) | 膵臓がんにおけるバイオマーカー | |
| Hesemans et al. | Development of Optical Imaging Strategies for Detection of EMT and Cancer Stem Cells: Initial in vitro Findings | |
| Dirix et al. | The Effect of Systemic Chemotherapy | |
| WO2025137381A1 (en) | Using extracellular vesicles to assess treatment efficacy of poly (adp-ribose) polymerase inhibitor therapies |