JP2009531376A5 - - Google Patents
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- Publication number
- JP2009531376A5 JP2009531376A5 JP2009502034A JP2009502034A JP2009531376A5 JP 2009531376 A5 JP2009531376 A5 JP 2009531376A5 JP 2009502034 A JP2009502034 A JP 2009502034A JP 2009502034 A JP2009502034 A JP 2009502034A JP 2009531376 A5 JP2009531376 A5 JP 2009531376A5
- Authority
- JP
- Japan
- Prior art keywords
- ylmethyl
- cyclopropylpiperazin
- benzothiazole
- isopropylpiperazin
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06111820 | 2006-03-28 | ||
| US78747806P | 2006-03-30 | 2006-03-30 | |
| EP06112425 | 2006-04-10 | ||
| US79428806P | 2006-04-21 | 2006-04-21 | |
| EP06026875 | 2006-12-24 | ||
| US90350307P | 2007-02-26 | 2007-02-26 | |
| PCT/EP2007/052751 WO2007110364A1 (en) | 2006-03-28 | 2007-03-22 | Benzothiazoles having histamine h3 receptor activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009531376A JP2009531376A (ja) | 2009-09-03 |
| JP2009531376A5 true JP2009531376A5 (OSRAM) | 2011-12-01 |
Family
ID=43124961
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009502034A Pending JP2009531376A (ja) | 2006-03-28 | 2007-03-22 | ヒスタミンｈ３受容体活性を有するベンゾチアゾール |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8394842B2 (OSRAM) |
| EP (1) | EP1999120B1 (OSRAM) |
| JP (1) | JP2009531376A (OSRAM) |
| KR (1) | KR101280333B1 (OSRAM) |
| CN (1) | CN101410385B (OSRAM) |
| AU (1) | AU2007229492B2 (OSRAM) |
| CA (1) | CA2645581A1 (OSRAM) |
| EA (1) | EA015569B1 (OSRAM) |
| ES (1) | ES2388681T3 (OSRAM) |
| IL (1) | IL193441A0 (OSRAM) |
| MX (1) | MX2008011123A (OSRAM) |
| NZ (1) | NZ570524A (OSRAM) |
| SG (1) | SG170785A1 (OSRAM) |
| WO (1) | WO2007110364A1 (OSRAM) |
| ZA (1) | ZA200806985B (OSRAM) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030236259A1 (en) * | 2002-02-05 | 2003-12-25 | Rolf Hohlweg | Novel aryl- and heteroarylpiperazines |
| BRPI0613564A2 (pt) | 2005-07-04 | 2011-01-18 | Novo Nordisk As | compostos, seus usos na preparação de composições farmacêuticas e composições farmacêuticas compreendendo os mesmos |
| US8318927B2 (en) * | 2006-05-23 | 2012-11-27 | High Point Pharmaceuticals, Llc | 6-(4-cyclopropylpiperazin-1-yl)-2′-methyl-[3, 4′]-bipyridine and its uses as a medicament |
| AU2007267197B2 (en) * | 2006-05-29 | 2011-12-01 | High Point Pharmaceuticals, Llc | 3- (1, 3-Benzodioxol-5-yl) -6- (4-cyclopropylpiperazin-1-yl) -pyridazine, its salts and solvates and its use as histamine H3 receptor antagonist |
| EP2014656A3 (en) * | 2007-06-11 | 2011-08-24 | High Point Pharmaceuticals, LLC | New heteocyclic h3 antagonists |
| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| US8153813B2 (en) * | 2007-12-20 | 2012-04-10 | Abbott Laboratories | Benzothiazole and benzooxazole derivatives and methods of use |
| BRPI0924844A2 (pt) * | 2009-03-24 | 2016-01-26 | Sanofi Sa | derivados de azacarbolinas 9h-pirrol[2,3-b:5,4-c']dipiridina, sua preparação e sua utilização terapêutica. |
| US8481547B2 (en) * | 2009-12-18 | 2013-07-09 | Janssen Pharmaceutica Nv | Substituted benzothiazole and benzoxazole derivatives useful as inhibitors of DPP-1 |
| ES2558531T3 (es) * | 2010-09-02 | 2016-02-05 | Suven Life Sciences Limited | Compuestos de heterociclilo como ligandos de receptores de histamina H3 |
| WO2012120053A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8901114B2 (en) | 2011-03-08 | 2014-12-02 | Sanofi | Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof |
| WO2012120056A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683699B1 (de) | 2011-03-08 | 2015-06-24 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683705B1 (de) | 2011-03-08 | 2015-04-22 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| AU2012267556B9 (en) | 2011-06-09 | 2017-05-11 | Rhizen Pharmaceuticals Sa | Novel compounds as modulators of GPR-119 |
| IN2014CN03597A (OSRAM) * | 2011-10-14 | 2015-10-09 | Ambit Biosciences Corp | |
| HK1220446A1 (en) * | 2013-06-10 | 2017-05-05 | Astellas Pharma Inc. | Bicyclic nitrogen-containing aromatic heterocyclic amide compound |
| TW201713650A (en) | 2015-06-22 | 2017-04-16 | Actelion Pharmaceuticals Ltd | NADPH oxidase 4 inhibitors |
| BR112018068066B1 (pt) * | 2016-03-11 | 2023-11-28 | Ac Immune Sa | Compostos bicíclicos e seu uso, composição diagnóstica e farmacêutica, misturas, métodos de coleção de dados para diagnóstico, para determinar uma predisposição a, para monitorar transtorno residual e para prever a capacidade de resposta de um paciente sofrendo de transtorno ou anormalidade associado com agregados de alfa-sinucleína, métodos para determinar a quantidade de agregados de alfa-sinucleína e para preparar um composto, kit teste e kit para preparar uma preparação radio farmacêutica |
| CN106588808A (zh) * | 2017-02-26 | 2017-04-26 | 长沙深橙生物科技有限公司 | 一种苯并[d]恶唑衍生物的制备方法 |
| AU2018282154B2 (en) | 2017-06-05 | 2022-04-07 | Ptc Therapeutics, Inc. | Compounds for treating huntington's disease |
| BR112020019373A2 (pt) | 2018-03-27 | 2020-12-29 | Ptc Therapeutics, Inc. | Compostos para o tratamento da doença de hutington |
| WO2020005877A1 (en) * | 2018-06-27 | 2020-01-02 | Ptc Therapeutics, Inc. | Heteroaryl compounds for treating huntington's disease |
| IL279688B2 (en) | 2018-06-27 | 2025-01-01 | Ptc Therapeutics Inc | Heterocyclic and heteroaryl compounds for the treatment of Huntington's disease |
| KR102682408B1 (ko) * | 2021-05-12 | 2024-07-05 | 에이치케이이노엔 주식회사 | 신규한 벤조티아졸 유도체, 이의 제조방법 및 이의 간질환 예방 또는 치료 용도 |
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|---|---|---|---|---|
| NZ187474A (en) * | 1977-06-10 | 1981-03-16 | Science Union & Cie | 4-heterocyclyl-piperazine-i-carbodithioic acids and salts and pharmaceutical compositions thereof |
| NO156497C (no) | 1984-10-18 | 1987-09-30 | Helge Boe | Anordning for sammenfoeyning av to plateformede elementer. |
| DE3511110A1 (de) | 1985-03-27 | 1986-10-02 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue pyridazinone, ihre herstellung und diese verbindungen enthaltende arzneimittel |
| PH25772A (en) | 1985-08-30 | 1991-10-18 | Novo Industri As | Insulin analogues, process for their preparation |
| FI91859C (fi) | 1987-06-17 | 1994-08-25 | Eisai Co Ltd | Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi |
| DE3837825A1 (de) | 1988-11-08 | 1990-05-10 | Hoechst Ag | Neue insulinderivate, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung |
| JP2869561B2 (ja) * | 1989-05-22 | 1999-03-10 | 大塚製薬株式会社 | 血小板粘着抑制剤 |
| JP2637303B2 (ja) * | 1991-04-16 | 1997-08-06 | 明治製菓株式会社 | 新規ベンゾチアゾール誘導体 |
| DE4223589A1 (de) | 1992-07-17 | 1994-01-20 | Fluehs Drehtechnik Gmbh | Ventiloberteil |
| WO1994022846A1 (en) | 1993-03-30 | 1994-10-13 | Pfizer Inc. | Compounds enhancing antitumor activity of other cytotoxic agents |
| JP3193560B2 (ja) | 1993-04-16 | 2001-07-30 | 明治製菓株式会社 | 新規ベンゾオキサゾール誘導体 |
| ATE176482T1 (de) | 1993-06-21 | 1999-02-15 | Novo Nordisk As | Asp-b28-insulinkristalle |
| DE69428134T2 (de) | 1993-09-17 | 2002-05-02 | Novo Nordisk A/S, Bagsvaerd | Acyliertes insulin |
| US5504188A (en) | 1994-06-16 | 1996-04-02 | Eli Lilly And Company | Preparation of stable zinc insulin analog crystals |
| US6130217A (en) | 1995-09-20 | 2000-10-10 | Pfizer Inc | Compounds enhancing antitumor activity of other cytotoxic agents |
| IL125071A0 (en) | 1996-01-17 | 1999-01-26 | Novo Nordisk As | Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives their preparation and use |
| JP3520177B2 (ja) | 1996-05-09 | 2004-04-19 | 明治製菓株式会社 | セロトニン５−ｈｔ３受容体部分活性薬 |
| WO1997041120A1 (en) | 1996-07-26 | 1997-11-06 | Dr. Reddy's Research Foundation | Thiazolidinedione compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions thereof |
| ES2283025T3 (es) | 1996-08-30 | 2007-10-16 | Novo Nordisk A/S | Derivados de glp-1.1. |
| JP4339402B2 (ja) | 1996-12-31 | 2009-10-07 | ドクター・レディーズ・ラボラトリーズ・リミテッド | 新規なヘテロ環化合物、これらの製造方法及びこれらを含有する薬学的組成物、並びに糖尿病及び関連疾患の治療におけるこれらの使用 |
| JP2001518069A (ja) | 1997-05-02 | 2001-10-09 | ドクター・レディーズ・リサーチ・ファウンデーション | 低脂質性、抗高血圧性特性を有する新規な抗糖尿病化合物、それらの製造方法及びそれらを含有する薬学的組成物 |
| US6613942B1 (en) | 1997-07-01 | 2003-09-02 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
| WO1999001423A1 (en) | 1997-07-01 | 1999-01-14 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
| CA2294830A1 (en) | 1997-07-16 | 1999-01-28 | John Bondo Hansen | Fused 1,2,4-thiadiazine derivatives, their preparation and use |
| KR20000068568A (ko) | 1997-07-17 | 2000-11-25 | 이데이 노부유끼 | 자기기록매체 및 이것을 이용한 자기기록 재생장치 |
| CA2306082A1 (en) | 1997-10-27 | 1999-05-06 | Agouron Pharmaceuticals, Inc. | Substituted 4-amino-thiazol-2-y compounds as cdks inhibitors |
| WO1999019313A1 (en) | 1997-10-27 | 1999-04-22 | Dr. Reddy's Research Foundation | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them |
| US6440961B1 (en) | 1997-10-27 | 2002-08-27 | Dr. Reddy's Research Foundation | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
| JP4391597B2 (ja) | 1997-12-02 | 2009-12-24 | ドクター・レディーズ・ラボラトリーズ・リミテッド | 抗糖尿病性、低脂質性及び抗高血圧性を有するチアゾリンジオンとオキサゾリジンジオン誘導体 |
| JPH11199573A (ja) * | 1998-01-07 | 1999-07-27 | Yamanouchi Pharmaceut Co Ltd | ５ｈｔ３受容体作動薬及び新規ベンゾチアゾール誘導体 |
| AU6190299A (en) | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
| EP1123292A1 (en) | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
| JP2002527501A (ja) | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | 新規化合物、その製造及び利用 |
| EP1123268A1 (en) | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | New compounds, their preparation and use |
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| JP2002527503A (ja) | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | 新規化合物類、それらの調製及び使用 |
| WO2000029409A1 (de) | 1998-11-17 | 2000-05-25 | Bayer Aktiengesellschaft | Neue heterocyclyl-substituierte oxazolidon-derivate |
| TW520370B (en) * | 1998-11-20 | 2003-02-11 | Meiji Seika Kaisha | Benzooxazole derivatives and a pharmaceutical composition containing the derivatives as an active ingredient |
| ATE242254T1 (de) | 1998-12-18 | 2003-06-15 | Novo Nordisk As | Kondensierte 1,2,4-thiadiazinderivate, ihre herstellung und verwendung |
| WO2000041121A1 (en) | 1999-01-07 | 2000-07-13 | Ccrewards.Com | Method and arrangement for issuance and management of digital coupons and sales offers |
| WO2000042026A1 (en) | 1999-01-15 | 2000-07-20 | Novo Nordisk A/S | Non-peptide glp-1 agonists |
| AU3831300A (en) | 1999-04-16 | 2000-11-02 | Dr. Reddy's Laboratories Limited | Novel polymorphic forms of an antidiabetic agent: process for their preparation and pharmaceutical compositions containing them |
| WO2000063189A1 (en) | 1999-04-16 | 2000-10-26 | Novo Nordisk A/S | Crystalline r- guanidines, arginine or (l) -arginine (2s) -2- ethoxy -3-{4- [2-(10h -phenoxazin -10-yl)ethoxy]phenyl}propanoate |
| WO2000063191A1 (en) | 1999-04-16 | 2000-10-26 | Dr. Reddy's Research Foundation | Novel polymorphic forms of an antidiabetic agent: process for their preparation and a pharmaceutical composition containing them |
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| RU2001131111A (ru) | 1999-04-20 | 2003-08-10 | Ново Нордиск А/С (DK) | Новые соединения, их получение и применение |
| AU3958100A (en) | 1999-04-20 | 2000-11-02 | Novo Nordisk A/S | New compounds, their preparation and use |
| EP1171431A1 (en) | 1999-04-20 | 2002-01-16 | Novo Nordisk A/S | Compounds, their preparation and use |
| GB0003254D0 (en) | 2000-02-11 | 2000-04-05 | Darwin Discovery Ltd | Heterocyclic compounds and their therapeutic use |
| ATE430730T1 (de) | 2000-03-31 | 2009-05-15 | Ortho Mcneil Pharm Inc | Phenyl-substituierte indole als h3 histaminrezeptorantagonisten |
| AU2001251083A1 (en) | 2000-03-31 | 2001-10-15 | Ortho-Mcneil Pharmaceutical, Inc. | Method for using 2-aryloxyalkylaminobenzoxazoles and 2-aryloxyalkylaminobenzothiazoles as h3 antagonists |
| DE60140708D1 (de) | 2000-08-10 | 2010-01-14 | Mitsubishi Tanabe Pharma Corp | Prolinderivative und deren Verwendung als Medikamente |
| US20030073672A1 (en) | 2001-09-05 | 2003-04-17 | Breitenbucher J. Guy | Method for treating allergies using substituted pyrazoles |
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| CN1628109A (zh) * | 2002-02-05 | 2005-06-15 | 诺沃挪第克公司 | 新颖的芳基－与杂芳基－哌嗪 |
| US7449464B2 (en) * | 2003-03-12 | 2008-11-11 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
| EP1620434B1 (en) * | 2003-05-07 | 2011-03-09 | Abbott Laboratories | Fused bicyclic-substituted amines as histamine-3 receptor ligands |
| TW200538433A (en) | 2004-02-24 | 2005-12-01 | Irm Llc | Immunosuppressant compounds and compositiions |
| WO2007038367A1 (en) | 2005-09-23 | 2007-04-05 | Memory Pharmaceuticals Corporation | Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof |
-
2007
- 2007-03-22 KR KR1020087023919A patent/KR101280333B1/ko not_active Expired - Fee Related
- 2007-03-22 CA CA002645581A patent/CA2645581A1/en not_active Abandoned
- 2007-03-22 US US12/294,756 patent/US8394842B2/en not_active Expired - Fee Related
- 2007-03-22 EA EA200870376A patent/EA015569B1/ru not_active IP Right Cessation
- 2007-03-22 AU AU2007229492A patent/AU2007229492B2/en not_active Ceased
- 2007-03-22 ES ES07727226T patent/ES2388681T3/es active Active
- 2007-03-22 NZ NZ570524A patent/NZ570524A/en not_active IP Right Cessation
- 2007-03-22 JP JP2009502034A patent/JP2009531376A/ja active Pending
- 2007-03-22 MX MX2008011123A patent/MX2008011123A/es active IP Right Grant
- 2007-03-22 CN CN2007800109712A patent/CN101410385B/zh not_active Expired - Fee Related
- 2007-03-22 SG SG201102188-8A patent/SG170785A1/en unknown
- 2007-03-22 EP EP07727226A patent/EP1999120B1/en active Active
- 2007-03-22 WO PCT/EP2007/052751 patent/WO2007110364A1/en not_active Ceased
-
2008
- 2008-08-13 ZA ZA2008/06985A patent/ZA200806985B/en unknown
- 2008-08-14 IL IL193441A patent/IL193441A0/en unknown
-
2012
- 2012-10-25 US US13/660,045 patent/US8772285B2/en not_active Expired - Fee Related