JP2009530282A5 - - Google Patents

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Publication number
JP2009530282A5
JP2009530282A5 JP2009500435A JP2009500435A JP2009530282A5 JP 2009530282 A5 JP2009530282 A5 JP 2009530282A5 JP 2009500435 A JP2009500435 A JP 2009500435A JP 2009500435 A JP2009500435 A JP 2009500435A JP 2009530282 A5 JP2009530282 A5 JP 2009530282A5
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JP
Japan
Prior art keywords
carbon
asterisk
enantiomer
indicated
formula
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JP2009500435A
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English (en)
Japanese (ja)
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JP2009530282A (ja
JP5313124B2 (ja
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Application filed filed Critical
Priority claimed from PCT/US2007/006320 external-priority patent/WO2007109023A1/en
Publication of JP2009530282A publication Critical patent/JP2009530282A/ja
Publication of JP2009530282A5 publication Critical patent/JP2009530282A5/ja
Application granted granted Critical
Publication of JP5313124B2 publication Critical patent/JP5313124B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2009500435A 2006-03-16 2007-03-14 立体的化合物を製造するための方法および中間体 Expired - Fee Related JP5313124B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US78297606P 2006-03-16 2006-03-16
US60/782,976 2006-03-16
US84477106P 2006-09-15 2006-09-15
US60/844,771 2006-09-15
PCT/US2007/006320 WO2007109023A1 (en) 2006-03-16 2007-03-14 Processes and intermediates for preparing steric compounds

Publications (3)

Publication Number Publication Date
JP2009530282A JP2009530282A (ja) 2009-08-27
JP2009530282A5 true JP2009530282A5 (OSRAM) 2010-05-06
JP5313124B2 JP5313124B2 (ja) 2013-10-09

Family

ID=38222510

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009500435A Expired - Fee Related JP5313124B2 (ja) 2006-03-16 2007-03-14 立体的化合物を製造するための方法および中間体

Country Status (14)

Country Link
US (3) US20070244334A1 (OSRAM)
EP (3) EP1993993A1 (OSRAM)
JP (1) JP5313124B2 (OSRAM)
KR (1) KR101398259B1 (OSRAM)
AR (1) AR059916A1 (OSRAM)
AU (1) AU2007227580A1 (OSRAM)
BR (1) BRPI0709568A2 (OSRAM)
CA (1) CA2646123A1 (OSRAM)
MX (1) MX2008011869A (OSRAM)
NZ (1) NZ571281A (OSRAM)
RU (1) RU2013105768A (OSRAM)
SG (1) SG170729A1 (OSRAM)
TW (2) TWI466851B (OSRAM)
WO (1) WO2007109023A1 (OSRAM)

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UA79749C2 (en) 1996-10-18 2007-07-25 Vertex Pharma Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease
SV2003000617A (es) 2000-08-31 2003-01-13 Lilly Co Eli Inhibidores de la proteasa peptidomimetica ref. x-14912m
TWI359147B (en) 2003-09-05 2012-03-01 Vertex Pharma Inhibitors of serine proteases, particularly hcv n
US8399615B2 (en) * 2005-08-19 2013-03-19 Vertex Pharmaceuticals Incorporated Processes and intermediates
US7964624B1 (en) 2005-08-26 2011-06-21 Vertex Pharmaceuticals Incorporated Inhibitors of serine proteases
AR055395A1 (es) 2005-08-26 2007-08-22 Vertex Pharma Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
AU2007217355B2 (en) 2006-02-27 2012-06-21 Vertex Pharmaceuticals Incorporated Co-crystals comprising VX-950 and pharmaceutical compositions comprising the same
EP2194039A1 (en) 2006-03-16 2010-06-09 Vertex Pharmceuticals Incorporated Process for preparing optically enriched compounds
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DE102006059317A1 (de) 2006-07-04 2008-01-10 Evonik Degussa Gmbh Verfahren zur Herstellung von β-Amino-α-hydroxy-carbonsäureamiden
DE102006042147A1 (de) * 2006-09-06 2008-03-27 Dynamit Nobel Gmbh Explosivstoff- Und Systemtechnik Hydrochloride von 3-Amino-2-hydroxycarbonsäureamiden
CN101903392A (zh) 2007-02-27 2010-12-01 弗特克斯药品有限公司 丝氨酸蛋白酶的抑制剂
CA2679312A1 (en) 2007-02-27 2008-09-04 Vertex Pharmaceuticals Incorporated Co-crystals and pharmaceutical compositions comprising the same
WO2009032198A1 (en) 2007-08-30 2009-03-12 Vertex Pharmaceuticals Incorporated Co-crystals and pharmaceutical compositions comprising the same
EP2861557A1 (en) 2012-06-13 2015-04-22 Janssen Pharmaceutica, N.V. A method for the preparation of 3-amino-n-cyclopropyl-2-hydroxyl-hexanamide
CN103508918B (zh) * 2012-06-18 2015-09-09 上海医药工业研究院 带有环丁基的α-羟基β-氨基酯类化合物及其制备方法
CN104470914A (zh) 2012-06-20 2015-03-25 桑多斯股份公司 替拉瑞韦和波普瑞韦或者其药学上可接受的盐或溶剂合物和中间产物包括经Mukaiyama羟醛加成制备的β-氨基酸的合成
WO2013189978A1 (en) 2012-06-20 2013-12-27 Sandoz Ag PROCESS FOR PREPARING ß-AMINO ACID DERIVATIVES AND USE OF SAID PROCESS FOR PREPARING TELAPREVIR
WO2014033667A1 (en) 2012-08-30 2014-03-06 Ranbaxy Laboratories Limited Process for the preparation of telaprevir
WO2014083582A2 (en) * 2012-11-29 2014-06-05 Msn Laboratories Limited Novel process for the preparation of (1s,3ar,6as)-2-[(2s)-2-({(2s)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-n-[(3s)-1-(cyclopropylamino)-1,2-dioxohexan-3-yl]-3,3a,4,5,6,6a-hexahydro-1h-cyclopenta[c] pyrrole-1-carboxamide and its intermediates
WO2014203208A1 (en) 2013-06-21 2014-12-24 Ranbaxy Laboratories Limited Process for the preparation of telaprevir and intermediates thereof
WO2014203224A1 (en) 2013-06-21 2014-12-24 Ranbaxy Laboratories Limited Process for the preparation of telaprevir and its intermediates
CN104926831A (zh) * 2014-03-20 2015-09-23 上海医药工业研究院 合成特拉匹韦的中间体及其制备方法
CN110577506B (zh) * 2018-06-07 2023-04-07 中国科学院上海有机化学研究所 (﹣)-三尖杉碱的酯类衍生物的合成方法及其中间体

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