JP2009529906A5 - - Google Patents

Info

Publication number

JP2009529906A5

JP2009529906A5 JP2009500939A JP2009500939A JP2009529906A5 JP 2009529906 A5 JP2009529906 A5 JP 2009529906A5 JP 2009500939 A JP2009500939 A JP 2009500939A JP 2009500939 A JP2009500939 A JP 2009500939A JP 2009529906 A5 JP2009529906 A5 JP 2009529906A5

Authority

JP

Japan

Prior art keywords

fusion protein

polypeptide

protein according

receptor

fusion

Prior art date

2007-03-22

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
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• 229920001184 polypeptide Polymers 0.000 claims 22
• 102000004196 processed proteins & peptides Human genes 0.000 claims 22
• 108090000765 processed proteins & peptides Proteins 0.000 claims 22
• 108020001507 fusion proteins Proteins 0.000 claims 18
• 102000037865 fusion proteins Human genes 0.000 claims 18
• 102000009109 Fc receptors Human genes 0.000 claims 8
• 108010087819 Fc receptors Proteins 0.000 claims 8
• 230000000890 antigenic effect Effects 0.000 claims 7
• 230000004927 fusion Effects 0.000 claims 4
• 239000000427 antigen Substances 0.000 claims 3
• 102000036639 antigens Human genes 0.000 claims 3
• 108091007433 antigens Proteins 0.000 claims 3
• 201000010099 disease Diseases 0.000 claims 3
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
• 238000000034 method Methods 0.000 claims 3
• 230000001717 pathogenic effect Effects 0.000 claims 3
• 230000003612 virological effect Effects 0.000 claims 3
• 108060003951 Immunoglobulin Proteins 0.000 claims 2
• 125000003295 alanine group Chemical group N[C@@H](C)C(=O)* 0.000 claims 2
• 125000003275 alpha amino acid group Chemical group 0.000 claims 2
• 230000001580 bacterial effect Effects 0.000 claims 2
• 230000002538 fungal effect Effects 0.000 claims 2
• 230000028993 immune response Effects 0.000 claims 2
• 102000018358 immunoglobulin Human genes 0.000 claims 2
• NFGXHKASABOEEW-UHFFFAOYSA-N 1-methylethyl 11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate Chemical compound COC(C)(C)CCCC(C)CC=CC(C)=CC(=O)OC(C)C NFGXHKASABOEEW-UHFFFAOYSA-N 0.000 claims 1
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 101710166488 6 kDa early secretory antigenic target Proteins 0.000 claims 1
• 208000035143 Bacterial infection Diseases 0.000 claims 1
• 206010017533 Fungal infection Diseases 0.000 claims 1
• 101710154606 Hemagglutinin Proteins 0.000 claims 1
• 241000711549 Hepacivirus C Species 0.000 claims 1
• 241000700721 Hepatitis B virus Species 0.000 claims 1
• 108010070875 Human Immunodeficiency Virus tat Gene Products Proteins 0.000 claims 1
• 241000712431 Influenza A virus Species 0.000 claims 1
• 241000187479 Mycobacterium tuberculosis Species 0.000 claims 1
• 208000031888 Mycoses Diseases 0.000 claims 1
• 108010006232 Neuraminidase Proteins 0.000 claims 1
• 102000005348 Neuraminidase Human genes 0.000 claims 1
• 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 1
• 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 1
• 208000030852 Parasitic disease Diseases 0.000 claims 1
• 101710176177 Protein A56 Proteins 0.000 claims 1
• 241000580858 Simian-Human immunodeficiency virus Species 0.000 claims 1
• 230000005867 T cell response Effects 0.000 claims 1
• 208000036142 Viral infection Diseases 0.000 claims 1
• 125000000613 asparagine group Chemical group N[C@@H](CC(N)=O)C(=O)* 0.000 claims 1
• 208000022362 bacterial infectious disease Diseases 0.000 claims 1
• 230000008827 biological function Effects 0.000 claims 1
• 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 1
• 230000001747 exhibiting effect Effects 0.000 claims 1
• 239000012634 fragment Substances 0.000 claims 1
• 125000000404 glutamine group Chemical group N[C@@H](CCC(N)=O)C(=O)* 0.000 claims 1
• 125000003630 glycyl group Chemical group [H]N([H])C([H])([H])C(*)=O 0.000 claims 1
• 239000000185 hemagglutinin Substances 0.000 claims 1
• 230000001939 inductive effect Effects 0.000 claims 1
• 208000015181 infectious disease Diseases 0.000 claims 1
• 125000005647 linker group Chemical group 0.000 claims 1
• 244000045947 parasite Species 0.000 claims 1
• 244000052769 pathogen Species 0.000 claims 1
• 108091033319 polynucleotide Proteins 0.000 claims 1
• 102000040430 polynucleotide Human genes 0.000 claims 1
• 239000002157 polynucleotide Substances 0.000 claims 1
• 108090000623 proteins and genes Proteins 0.000 claims 1
• 125000003607 serino group Chemical group [H]N([H])[C@]([H])(C(=O)[*])C(O[H])([H])[H] 0.000 claims 1
• 125000006850 spacer group Chemical group 0.000 claims 1
• 241000712461 unidentified influenza virus Species 0.000 claims 1