CN101448854A - 包含结合Fc受体的多肽和抗原性多肽的用于介导免疫应答的融合蛋白 - Google Patents
包含结合Fc受体的多肽和抗原性多肽的用于介导免疫应答的融合蛋白 Download PDFInfo
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- CN101448854A CN101448854A CNA2007800185186A CN200780018518A CN101448854A CN 101448854 A CN101448854 A CN 101448854A CN A2007800185186 A CNA2007800185186 A CN A2007800185186A CN 200780018518 A CN200780018518 A CN 200780018518A CN 101448854 A CN101448854 A CN 101448854A
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0605735.0A GB0605735D0 (en) | 2006-03-22 | 2006-03-22 | Composition and method for mediating an immune response |
| GB0605735.0 | 2006-03-22 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2013102732781A Division CN103396495A (zh) | 2006-03-22 | 2007-03-22 | 包含结合Fc受体的多肽和抗原性多肽的用于介导免疫应答的融合蛋白 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101448854A true CN101448854A (zh) | 2009-06-03 |
Family
ID=36383953
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2013102732781A Pending CN103396495A (zh) | 2006-03-22 | 2007-03-22 | 包含结合Fc受体的多肽和抗原性多肽的用于介导免疫应答的融合蛋白 |
| CNA2007800185186A Pending CN101448854A (zh) | 2006-03-22 | 2007-03-22 | 包含结合Fc受体的多肽和抗原性多肽的用于介导免疫应答的融合蛋白 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2013102732781A Pending CN103396495A (zh) | 2006-03-22 | 2007-03-22 | 包含结合Fc受体的多肽和抗原性多肽的用于介导免疫应答的融合蛋白 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20090186025A1 (enExample) |
| EP (1) | EP2007807A2 (enExample) |
| JP (1) | JP2009529906A (enExample) |
| CN (2) | CN103396495A (enExample) |
| GB (1) | GB0605735D0 (enExample) |
| WO (1) | WO2007107797A2 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106337040A (zh) * | 2016-08-28 | 2017-01-18 | 苏州普罗达生物科技有限公司 | 一种内皮细胞受体蛋白酪氨酸激酶a2免疫原多肽及其用途 |
| CN107207603A (zh) * | 2015-02-03 | 2017-09-26 | 吉安特科技股份有限公司 | 趋化因子‑免疫球蛋白融合多肽,其组合物、制备方法以及用途 |
| CN116916950A (zh) * | 2021-03-04 | 2023-10-20 | 螺旋纳米技术公司 | 包含Sbi佐剂的组合物及其使用方法 |
| CN119841940A (zh) * | 2025-03-19 | 2025-04-18 | 中国人民解放军军事科学院军事医学研究院 | 一种抗基孔肯雅病毒e蛋白的纳米抗体n033及其应用 |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0615266D0 (en) * | 2006-08-01 | 2006-09-06 | Immunobiology Ltd | Composition and method for mediating an immune response |
| KR101722305B1 (ko) | 2007-01-30 | 2017-03-31 | 에피백스, 인크. | 조절 t 세포 에피토프, 그의 조성물 및 용도 |
| TWI422594B (zh) | 2007-02-02 | 2014-01-11 | Baylor Res Inst | 經由樹狀細胞去唾液酸糖蛋白受體(dc-asgpr)接合抗原呈現細胞之藥劑 |
| CN101679949B (zh) * | 2007-02-23 | 2015-08-19 | 贝勒研究院 | 通过dectin-1激活人抗原呈递细胞的治疗性应用 |
| AU2010303568B2 (en) * | 2009-10-09 | 2014-07-31 | New York Blood Center, Inc. | Immunopotentiator-linked oligomeric influenza immunogenic compositions |
| US9962436B2 (en) * | 2012-07-26 | 2018-05-08 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Multimeric fusion protein vaccine and immunotherapeutic |
| IL300029A (en) | 2014-05-16 | 2023-03-01 | Baylor Res Institute | Methods and preparations for the treatment of autoimmune and inflammatory conditions |
| CN106146670B (zh) * | 2015-04-24 | 2019-01-15 | 宜明昂科生物医药技术(上海)有限公司 | 一种新的重组双功能融合蛋白及其制备和应用 |
| CN106366179A (zh) * | 2016-08-28 | 2017-02-01 | 苏州普罗达生物科技有限公司 | 一种跨膜硫酸乙酰肝泰蛋白多糖1免疫激动剂多肽及其用途 |
| CN106366180A (zh) * | 2016-08-28 | 2017-02-01 | 苏州普罗达生物科技有限公司 | 一种上皮生长因子受体免疫原多肽及其用途 |
| CN113412123A (zh) * | 2018-12-28 | 2021-09-17 | 豪夫迈·罗氏有限公司 | 用于免疫应答增强的患者的治疗性用途的肽-mhc-i-抗体融合蛋白 |
| CN110093360B (zh) * | 2019-04-15 | 2021-06-15 | 华南农业大学 | 一种表达Fc片段的狂犬病病毒G蛋白的融合蛋白及其制备方法 |
| CN112870344B (zh) * | 2019-11-29 | 2022-07-19 | 北京绿竹生物技术股份有限公司 | 一种重组水痘带状疱疹病毒疫苗 |
| CN110872358B (zh) * | 2019-12-04 | 2021-12-10 | 天康制药(苏州)有限公司 | HA-Fc融合蛋白及其制备方法和疫苗 |
| CN116769014A (zh) * | 2023-06-07 | 2023-09-19 | 河南省农业科学院动物免疫学重点实验室 | 一种牛IgG Fc受体boFcγRI的线性配体结合表位 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5969109A (en) * | 1990-02-28 | 1999-10-19 | Bona; Constantin | Chimeric antibodies comprising antigen binding sites and B and T cell epitopes |
| ATE204300T1 (de) * | 1994-05-13 | 2001-09-15 | Biovation Ltd | Zielzellen-bindende chimäre peptide |
| US6391589B1 (en) * | 1994-08-23 | 2002-05-21 | Human Genome Sciences, Inc. | Human chemokine beta-10 mutant polypeptides |
| EP1093464A2 (en) * | 1998-07-06 | 2001-04-25 | The University Of Tennessee Research Corporation | Compounds, compositions and methods for the endocytic presentation of immunosuppressive factors |
| US7183387B1 (en) * | 1999-01-15 | 2007-02-27 | Genentech, Inc. | Polypeptide variants with altered effector function |
| US7067110B1 (en) * | 1999-07-21 | 2006-06-27 | Emd Lexigen Research Center Corp. | Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens |
| PT1346041E (pt) * | 2000-11-27 | 2007-06-05 | Praecis Pharm Inc | Agentes terapêuticos e métodos para a sua utilização no tratamento de uma doença amiloidogénica. |
| GB0102145D0 (en) * | 2001-01-26 | 2001-03-14 | Scancell Ltd | Substances |
| US20040002587A1 (en) * | 2002-02-20 | 2004-01-01 | Watkins Jeffry D. | Fc region variants |
| US8025873B2 (en) * | 2002-06-20 | 2011-09-27 | Paladin Labs, Inc. | Chimeric antigens for eliciting an immune response |
| US8007805B2 (en) * | 2003-08-08 | 2011-08-30 | Paladin Labs, Inc. | Chimeric antigens for breaking host tolerance to foreign antigens |
-
2006
- 2006-03-22 GB GBGB0605735.0A patent/GB0605735D0/en not_active Ceased
-
2007
- 2007-03-22 CN CN2013102732781A patent/CN103396495A/zh active Pending
- 2007-03-22 JP JP2009500939A patent/JP2009529906A/ja active Pending
- 2007-03-22 US US12/225,454 patent/US20090186025A1/en not_active Abandoned
- 2007-03-22 CN CNA2007800185186A patent/CN101448854A/zh active Pending
- 2007-03-22 WO PCT/GB2007/050143 patent/WO2007107797A2/en not_active Ceased
- 2007-03-22 EP EP07733568A patent/EP2007807A2/en not_active Withdrawn
-
2012
- 2012-05-11 US US13/470,227 patent/US20120225067A1/en not_active Abandoned
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107207603A (zh) * | 2015-02-03 | 2017-09-26 | 吉安特科技股份有限公司 | 趋化因子‑免疫球蛋白融合多肽,其组合物、制备方法以及用途 |
| CN106337040A (zh) * | 2016-08-28 | 2017-01-18 | 苏州普罗达生物科技有限公司 | 一种内皮细胞受体蛋白酪氨酸激酶a2免疫原多肽及其用途 |
| CN116916950A (zh) * | 2021-03-04 | 2023-10-20 | 螺旋纳米技术公司 | 包含Sbi佐剂的组合物及其使用方法 |
| US12343392B2 (en) | 2021-03-04 | 2025-07-01 | Helix Nanotechnologies Inc | Compositions including Sbi adjuvants and methods of use thereof |
| CN119841940A (zh) * | 2025-03-19 | 2025-04-18 | 中国人民解放军军事科学院军事医学研究院 | 一种抗基孔肯雅病毒e蛋白的纳米抗体n033及其应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20090186025A1 (en) | 2009-07-23 |
| US20120225067A1 (en) | 2012-09-06 |
| EP2007807A2 (en) | 2008-12-31 |
| GB0605735D0 (en) | 2006-05-03 |
| WO2007107797A2 (en) | 2007-09-27 |
| JP2009529906A (ja) | 2009-08-27 |
| WO2007107797A3 (en) | 2007-11-08 |
| CN103396495A (zh) | 2013-11-20 |
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Application publication date: 20090603 |
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