JP2009528340A5 - - Google Patents
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- Publication number
- JP2009528340A5 JP2009528340A5 JP2008556861A JP2008556861A JP2009528340A5 JP 2009528340 A5 JP2009528340 A5 JP 2009528340A5 JP 2008556861 A JP2008556861 A JP 2008556861A JP 2008556861 A JP2008556861 A JP 2008556861A JP 2009528340 A5 JP2009528340 A5 JP 2009528340A5
- Authority
- JP
- Japan
- Prior art keywords
- oxaliplatin
- liposomes
- effective amount
- negatively charged
- mixing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- DWAFYCQODLXJNR-BNTLRKBRSA-L oxaliplatin Chemical compound O1C(=O)C(=O)O[Pt]11N[C@@H]2CCCC[C@H]2N1 DWAFYCQODLXJNR-BNTLRKBRSA-L 0.000 claims 12
- 229960001756 oxaliplatin Drugs 0.000 claims 12
- 239000002502 liposome Substances 0.000 claims 9
- 238000000034 method Methods 0.000 claims 6
- 239000000693 micelle Substances 0.000 claims 6
- AWUCVROLDVIAJX-UHFFFAOYSA-N alpha-glycerophosphate Natural products OCC(O)COP(O)(O)=O AWUCVROLDVIAJX-UHFFFAOYSA-N 0.000 claims 4
- 150000002632 lipids Chemical class 0.000 claims 3
- ATBOMIWRCZXYSZ-XZBBILGWSA-N [1-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-3-hexadecanoyloxypropan-2-yl] (9e,12e)-octadeca-9,12-dienoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(COP(O)(=O)OCC(O)CO)OC(=O)CCCCCCC\C=C\C\C=C\CCCCC ATBOMIWRCZXYSZ-XZBBILGWSA-N 0.000 claims 2
- -1 phosphatidylglycerol lipid Chemical class 0.000 claims 2
- 239000002904 solvent Substances 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 102000044209 Tumor Suppressor Genes Human genes 0.000 claims 1
- 108700025716 Tumor Suppressor Genes Proteins 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR20060100144A GR20060100144A (el) | 2006-03-03 | 2006-03-03 | Θεραπεια του καρκινου με χρηση οξαλιπλατινης εγκλεισμενης μεσα σε λιποσωματα και απο κοινου εγκλεισμος στο λιποσωμιακο μοριο περισσοτερων απο ενος φαρμακευτικου παρασκευασματος h gene |
| PCT/GR2007/000015 WO2007099377A2 (en) | 2006-03-03 | 2007-03-05 | Cancer treatments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009528340A JP2009528340A (ja) | 2009-08-06 |
| JP2009528340A5 true JP2009528340A5 (https=) | 2010-04-22 |
Family
ID=38325437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008556861A Pending JP2009528340A (ja) | 2006-03-03 | 2007-03-05 | 癌治療 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20090053302A1 (https=) |
| EP (1) | EP2001441A2 (https=) |
| JP (1) | JP2009528340A (https=) |
| KR (1) | KR20090023548A (https=) |
| CN (1) | CN101522172A (https=) |
| AU (1) | AU2007220263A1 (https=) |
| BR (1) | BRPI0707059A2 (https=) |
| CA (1) | CA2644566A1 (https=) |
| EA (1) | EA200801912A1 (https=) |
| GR (1) | GR20060100144A (https=) |
| MA (1) | MA30314B1 (https=) |
| MX (1) | MX2008011263A (https=) |
| NO (1) | NO20083927L (https=) |
| RS (1) | RS20080388A (https=) |
| TN (1) | TNSN08345A1 (https=) |
| WO (1) | WO2007099377A2 (https=) |
| ZA (1) | ZA200807934B (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9186322B2 (en) * | 2002-08-02 | 2015-11-17 | Insmed Incorporated | Platinum aggregates and process for producing the same |
| US9107824B2 (en) | 2005-11-08 | 2015-08-18 | Insmed Incorporated | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
| KR20080094473A (ko) * | 2007-04-20 | 2008-10-23 | 한국화학연구원 | 음이온성 지질나노입자 및 이의 제조방법 |
| USRE45471E1 (en) * | 2008-01-28 | 2015-04-14 | Nanocarrier Co., Ltd. | Pharmaceutical composition or combination drug |
| TWI468188B (zh) * | 2008-01-30 | 2015-01-11 | Univ Tokushima | Anti-cancer effect enhancers consisting of oxaliplatin liposomal preparations and anticancer agents comprising the formulation |
| CA2753844A1 (en) * | 2008-03-05 | 2009-09-11 | Vicus Therapeutics, Llc | Compositions and methods for mucositis and oncology therapies |
| EP2123258A1 (en) * | 2008-05-23 | 2009-11-25 | Liplasome Pharma A/S | Liposomes for drug delivery |
| US20120135064A1 (en) * | 2009-05-27 | 2012-05-31 | Northeastern University | Conjugated nanodelivery vehicles |
| EP2481396A4 (en) * | 2009-09-21 | 2014-03-05 | Jw Pharmaceutical Corp | OXALIPLATIN NANOPARTICLES AND MANUFACTURING METHOD THEREFOR |
| JP5817053B2 (ja) * | 2010-04-02 | 2015-11-18 | 国立大学法人 千葉大学 | 腫瘍特異性を有するリポソーム |
| CN102133176B (zh) * | 2011-03-22 | 2012-09-05 | 济南宏瑞创博医药科技开发有限公司 | 一种奥沙利铂胶束制剂及其制备方法及应用 |
| JP5378469B2 (ja) * | 2011-08-11 | 2013-12-25 | 学校法人 日本歯科大学 | 医療用薬剤 |
| EP2883542B1 (en) | 2012-08-10 | 2019-05-01 | Taiho Pharmaceutical Co., Ltd. | Stable oxaliplatin-encapsulating liposome aqueous dispersion and method for stabilizing same |
| MA37931A1 (fr) * | 2012-08-13 | 2016-07-29 | Teni Boulikas | Procédés améliorés permettant de traiter un cancer avec une toxicité rénale réduite |
| SG11201501147WA (en) * | 2012-08-13 | 2015-04-29 | Regulon Inc | Methods for treatment of cancer using lipoplatin |
| CN121606602A (zh) | 2012-09-04 | 2026-03-06 | 埃莱森制药股份有限公司 | 用顺铂脂质复合物预防癌症的肺部复发 |
| EA023757B1 (ru) * | 2012-12-24 | 2016-07-29 | Общество С Ограниченной Ответственностью "Технология Лекарств" | Способ получения липосомальной формы оксалиплатина |
| EP2968144A1 (en) * | 2013-03-13 | 2016-01-20 | Mallinckrodt LLC | Liposome oxaliplatin compositions for cancer therapy |
| RU2668125C2 (ru) * | 2013-03-27 | 2018-09-26 | Тайхо Фармасьютикал Ко., Лтд. | Противоопухолевое лекарственное средство, включающее низкодозированный гидрохлорида иринотекана гидрат |
| CN103622912B (zh) * | 2013-12-05 | 2016-02-24 | 常州金远药业制造有限公司 | 盐酸多柔比星-多西他赛或紫杉醇脂质体制剂及其制备方法 |
| CN107921005A (zh) * | 2015-02-13 | 2018-04-17 | 友杏生技医药股份有限公司 | 利用纳米颗粒治疗肿瘤的组合物和方法 |
| CA2977397A1 (en) | 2015-03-03 | 2016-09-09 | Cureport, Inc. | Dual loaded liposomal pharmaceutical formulations |
| CN107530283A (zh) | 2015-03-03 | 2018-01-02 | 奎尔波特股份有限公司 | 组合脂质体药物制剂 |
| KR101687735B1 (ko) * | 2015-09-18 | 2016-12-19 | 서울대학교 산학협력단 | 신규의 동결건조보조제 및 새로운 인지질 용해용 혼합용매를 이용한 리포좀 동결분체의 제조방법 |
| US20190307690A1 (en) * | 2016-05-03 | 2019-10-10 | The American University In Cairo | Liposomal Delivery Systems for Oxaliplatin and in Dual Drug Delivery in Combination with Chemo-sensitizing and Chemo-therapeutic agents |
| WO2017192863A1 (en) | 2016-05-04 | 2017-11-09 | L.E.A.F. Holdings Group Llc | Targeted liposomal gemcitabine compositions and methods thereof |
| CN106074379B (zh) * | 2016-07-11 | 2019-01-25 | 中国科学院上海药物研究所 | 聚乙二醇化奥沙利铂前药及其制备方法和用途 |
| CN112656764B (zh) * | 2020-12-28 | 2022-09-02 | 吉林大学 | 一种紫杉醇铂类共载靶向长循环脂质体及应用 |
| CN114814023B (zh) * | 2022-04-24 | 2024-07-30 | 江苏省中医院 | 脂质分子在作为胃癌化疗药耐药的预测性标志物中的应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6060080A (en) * | 1990-07-16 | 2000-05-09 | Daiichi Pharmaceutical Co., Ltd. | Liposomal products |
| CA2046997C (en) * | 1990-07-16 | 2000-12-12 | Hiroshi Kikuchi | Liposomal products |
| US6511676B1 (en) * | 1999-11-05 | 2003-01-28 | Teni Boulikas | Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes |
| CN1254234C (zh) * | 2000-06-09 | 2006-05-03 | 莱古伦公司 | 质粒dna(lipogenestm)和含细胞核定位信号/促融合肽缀合物的治疗剂包封到定向脂质体复合体中 |
| CA2383259A1 (en) * | 2002-04-23 | 2003-10-23 | Celator Technologies Inc. | Synergistic compositions |
| JP3415131B1 (ja) * | 2002-06-03 | 2003-06-09 | メビオファーム株式会社 | リポソーム製剤 |
| US20040022842A1 (en) * | 2002-06-03 | 2004-02-05 | Mebiopharm Co., Ltd. | Liposome preparations containing oxaliplatin |
| JP2006502233A (ja) * | 2002-08-02 | 2006-01-19 | トランセーブ，インク． | 白金凝集物およびその製造方法 |
| WO2004098524A2 (en) * | 2003-05-02 | 2004-11-18 | Aronex Pharmaceuticals, Inc. | Lipid platinum complexes and methods of use thereof |
| EP1643971A2 (en) * | 2003-05-22 | 2006-04-12 | Neopharm, Inc. | Liposomal formulations comprising a combination of two or more active agents |
-
2006
- 2006-03-03 GR GR20060100144A patent/GR20060100144A/el not_active IP Right Cessation
-
2007
- 2007-03-05 CA CA002644566A patent/CA2644566A1/en not_active Abandoned
- 2007-03-05 EA EA200801912A patent/EA200801912A1/ru unknown
- 2007-03-05 JP JP2008556861A patent/JP2009528340A/ja active Pending
- 2007-03-05 US US12/281,541 patent/US20090053302A1/en not_active Abandoned
- 2007-03-05 KR KR1020087024248A patent/KR20090023548A/ko not_active Ceased
- 2007-03-05 BR BRPI0707059-4A patent/BRPI0707059A2/pt not_active IP Right Cessation
- 2007-03-05 CN CNA2007800139281A patent/CN101522172A/zh active Pending
- 2007-03-05 EP EP07712997A patent/EP2001441A2/en not_active Withdrawn
- 2007-03-05 AU AU2007220263A patent/AU2007220263A1/en not_active Abandoned
- 2007-03-05 MX MX2008011263A patent/MX2008011263A/es not_active Application Discontinuation
- 2007-03-05 RS RSP-2008/0388A patent/RS20080388A/sr unknown
- 2007-03-05 WO PCT/GR2007/000015 patent/WO2007099377A2/en not_active Ceased
-
2008
- 2008-09-02 MA MA31204A patent/MA30314B1/fr unknown
- 2008-09-03 TN TNP2008000345A patent/TNSN08345A1/en unknown
- 2008-09-15 NO NO20083927A patent/NO20083927L/no not_active Application Discontinuation
- 2008-09-16 ZA ZA200807934A patent/ZA200807934B/xx unknown
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