CN101522172A - 癌症治疗 - Google Patents

癌症治疗 Download PDF

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Publication number
CN101522172A
CN101522172A CNA2007800139281A CN200780013928A CN101522172A CN 101522172 A CN101522172 A CN 101522172A CN A2007800139281 A CNA2007800139281 A CN A2007800139281A CN 200780013928 A CN200780013928 A CN 200780013928A CN 101522172 A CN101522172 A CN 101522172A
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CN
China
Prior art keywords
oxaliplatin
liposome
cancer
liposomes
drug
Prior art date
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Pending
Application number
CNA2007800139281A
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English (en)
Chinese (zh)
Inventor
帕斯尼奥斯·布利卡斯
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Individual
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Individual
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Publication of CN101522172A publication Critical patent/CN101522172A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNA2007800139281A 2006-03-03 2007-03-05 癌症治疗 Pending CN101522172A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GR20060100144A GR20060100144A (el) 2006-03-03 2006-03-03 Θεραπεια του καρκινου με χρηση οξαλιπλατινης εγκλεισμενης μεσα σε λιποσωματα και απο κοινου εγκλεισμος στο λιποσωμιακο μοριο περισσοτερων απο ενος φαρμακευτικου παρασκευασματος h gene
GR20060100144 2006-03-03

Publications (1)

Publication Number Publication Date
CN101522172A true CN101522172A (zh) 2009-09-02

Family

ID=38325437

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2007800139281A Pending CN101522172A (zh) 2006-03-03 2007-03-05 癌症治疗

Country Status (17)

Country Link
US (1) US20090053302A1 (https=)
EP (1) EP2001441A2 (https=)
JP (1) JP2009528340A (https=)
KR (1) KR20090023548A (https=)
CN (1) CN101522172A (https=)
AU (1) AU2007220263A1 (https=)
BR (1) BRPI0707059A2 (https=)
CA (1) CA2644566A1 (https=)
EA (1) EA200801912A1 (https=)
GR (1) GR20060100144A (https=)
MA (1) MA30314B1 (https=)
MX (1) MX2008011263A (https=)
NO (1) NO20083927L (https=)
RS (1) RS20080388A (https=)
TN (1) TNSN08345A1 (https=)
WO (1) WO2007099377A2 (https=)
ZA (1) ZA200807934B (https=)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102133176A (zh) * 2011-03-22 2011-07-27 济南宏瑞创博医药科技开发有限公司 一种奥沙利铂胶束制剂及其制备方法及应用
CN103622912A (zh) * 2013-12-05 2014-03-12 常州金远药业制造有限公司 盐酸多柔比星-多西他赛或紫杉醇脂质体制剂及其制备方法
CN106074379A (zh) * 2016-07-11 2016-11-09 中国科学院上海药物研究所 聚乙二醇化奥沙利铂前药及其制备方法和用途
CN112656764A (zh) * 2020-12-28 2021-04-16 吉林大学 一种紫杉醇铂类共载靶向长循环脂质体及应用
CN114814023A (zh) * 2022-04-24 2022-07-29 江苏省中医院 脂质分子在作为胃癌化疗药耐药的预测性标志物中的应用

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9186322B2 (en) 2002-08-02 2015-11-17 Insmed Incorporated Platinum aggregates and process for producing the same
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
KR20080094473A (ko) * 2007-04-20 2008-10-23 한국화학연구원 음이온성 지질나노입자 및 이의 제조방법
KR101560339B1 (ko) * 2008-01-28 2015-10-14 나노캐리어 가부시키가이샤 의약 조성물 또는 조합제
TWI468188B (zh) * 2008-01-30 2015-01-11 Univ Tokushima Anti-cancer effect enhancers consisting of oxaliplatin liposomal preparations and anticancer agents comprising the formulation
WO2009111648A1 (en) * 2008-03-05 2009-09-11 Vicus Therapeutics, Llc Compositions and methods for mucositis and oncology therapies
EP2123258A1 (en) * 2008-05-23 2009-11-25 Liplasome Pharma A/S Liposomes for drug delivery
WO2010138550A1 (en) * 2009-05-27 2010-12-02 Northeastern University Conjugated nanodelivery vehicles
IN2012DN02576A (https=) * 2009-09-21 2015-08-28 Jw Pharmaceutical Corportion
JP5817053B2 (ja) * 2010-04-02 2015-11-18 国立大学法人 千葉大学 腫瘍特異性を有するリポソーム
JP5378469B2 (ja) 2011-08-11 2013-12-25 学校法人 日本歯科大学 医療用薬剤
EP2883542B1 (en) 2012-08-10 2019-05-01 Taiho Pharmaceutical Co., Ltd. Stable oxaliplatin-encapsulating liposome aqueous dispersion and method for stabilizing same
US20150258139A1 (en) * 2012-08-13 2015-09-17 Regulon, Inc. Methods for treatment of cancer using lipoplatin
MA37931A1 (fr) * 2012-08-13 2016-07-29 Teni Boulikas Procédés améliorés permettant de traiter un cancer avec une toxicité rénale réduite
DK2892524T3 (da) 2012-09-04 2021-01-25 Eleison Pharmaceuticals LLC Forebyggelse af pulmonalt kræfttilbagefald med lipid-komplekseret cisplatin
EA023757B1 (ru) * 2012-12-24 2016-07-29 Общество С Ограниченной Ответственностью "Технология Лекарств" Способ получения липосомальной формы оксалиплатина
CA2903234C (en) * 2013-03-13 2018-08-28 Mallinckrodt Llc Liposome oxaliplatin compositions for cancer therapy
JP6002835B2 (ja) * 2013-03-27 2016-10-05 大鵬薬品工業株式会社 低用量イリノテカン塩酸塩水和物を含有する抗腫瘍剤
AU2016219004A1 (en) * 2015-02-13 2017-09-07 Op Nano Co., Ltd. Compositions and methods of tumor treatment utilizing nanoparticles
US9895313B2 (en) 2015-03-03 2018-02-20 Cureport, Inc. Combination liposomal pharmaceutical formulations
EP3265063A4 (en) 2015-03-03 2018-11-07 Cureport, Inc. Dual loaded liposomal pharmaceutical formulations
KR101687735B1 (ko) * 2015-09-18 2016-12-19 서울대학교 산학협력단 신규의 동결건조보조제 및 새로운 인지질 용해용 혼합용매를 이용한 리포좀 동결분체의 제조방법
WO2017192502A1 (en) * 2016-05-03 2017-11-09 The American University In Cairo Liposomal delivery systems for oxaliplatin and in dual drug delivery in combination with chemo-sensitizing and chemo-therapeutic agents
WO2017192863A1 (en) * 2016-05-04 2017-11-09 L.E.A.F. Holdings Group Llc Targeted liposomal gemcitabine compositions and methods thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6060080A (en) * 1990-07-16 2000-05-09 Daiichi Pharmaceutical Co., Ltd. Liposomal products
CA2046997C (en) * 1990-07-16 2000-12-12 Hiroshi Kikuchi Liposomal products
US6511676B1 (en) * 1999-11-05 2003-01-28 Teni Boulikas Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes
AU2001275423B2 (en) * 2000-06-09 2007-01-11 Regulon, Inc. Encapsulation of polynucleotides and drugs into targeted liposomes
CA2383259A1 (en) * 2002-04-23 2003-10-23 Celator Technologies Inc. Synergistic compositions
US20040022842A1 (en) * 2002-06-03 2004-02-05 Mebiopharm Co., Ltd. Liposome preparations containing oxaliplatin
JP3415131B1 (ja) * 2002-06-03 2003-06-09 メビオファーム株式会社 リポソーム製剤
EP1545459A4 (en) * 2002-08-02 2007-08-22 Transave Inc PLATINUM AGGREGATES, AND METHOD FOR MANUFACTURING THE SAME
JP2006525368A (ja) * 2003-05-02 2006-11-09 アロネックス，ファーマシューティカルズ，インコーポレーテッド 脂質白金錯体およびその使用方法
EP1643971A2 (en) * 2003-05-22 2006-04-12 Neopharm, Inc. Liposomal formulations comprising a combination of two or more active agents

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102133176A (zh) * 2011-03-22 2011-07-27 济南宏瑞创博医药科技开发有限公司 一种奥沙利铂胶束制剂及其制备方法及应用
CN102133176B (zh) * 2011-03-22 2012-09-05 济南宏瑞创博医药科技开发有限公司 一种奥沙利铂胶束制剂及其制备方法及应用
CN103622912A (zh) * 2013-12-05 2014-03-12 常州金远药业制造有限公司 盐酸多柔比星-多西他赛或紫杉醇脂质体制剂及其制备方法
CN103622912B (zh) * 2013-12-05 2016-02-24 常州金远药业制造有限公司 盐酸多柔比星-多西他赛或紫杉醇脂质体制剂及其制备方法
CN106074379A (zh) * 2016-07-11 2016-11-09 中国科学院上海药物研究所 聚乙二醇化奥沙利铂前药及其制备方法和用途
CN106074379B (zh) * 2016-07-11 2019-01-25 中国科学院上海药物研究所 聚乙二醇化奥沙利铂前药及其制备方法和用途
CN112656764A (zh) * 2020-12-28 2021-04-16 吉林大学 一种紫杉醇铂类共载靶向长循环脂质体及应用
CN114814023A (zh) * 2022-04-24 2022-07-29 江苏省中医院 脂质分子在作为胃癌化疗药耐药的预测性标志物中的应用

Also Published As

Publication number Publication date
MA30314B1 (fr) 2009-04-01
RS20080388A (sr) 2009-07-15
AU2007220263A1 (en) 2007-09-07
WO2007099377A3 (en) 2008-04-17
CA2644566A1 (en) 2007-09-07
MX2008011263A (es) 2008-12-12
KR20090023548A (ko) 2009-03-05
WO2007099377A2 (en) 2007-09-07
EA200801912A1 (ru) 2009-02-27
EP2001441A2 (en) 2008-12-17
NO20083927L (no) 2008-09-15
TNSN08345A1 (en) 2009-12-29
JP2009528340A (ja) 2009-08-06
US20090053302A1 (en) 2009-02-26
GR20060100144A (el) 2007-10-17
ZA200807934B (en) 2009-11-25
BRPI0707059A2 (pt) 2011-04-19

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SE01 Entry into force of request for substantive examination
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Application publication date: 20090902