BRPI0707059A2 - método de formação de uma micela que compreende oxaliplatina, método de encapsulação de oxaliplatina em um lipossomo, micela, lipossomo, lipossomo que compreende uma quantidade eficaz de oxaliplatina, uso de um lipossomo, método de tratamento de cáncer e terapia de combinação - Google Patents
método de formação de uma micela que compreende oxaliplatina, método de encapsulação de oxaliplatina em um lipossomo, micela, lipossomo, lipossomo que compreende uma quantidade eficaz de oxaliplatina, uso de um lipossomo, método de tratamento de cáncer e terapia de combinação Download PDFInfo
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- BRPI0707059A2 BRPI0707059A2 BRPI0707059-4A BRPI0707059A BRPI0707059A2 BR PI0707059 A2 BRPI0707059 A2 BR PI0707059A2 BR PI0707059 A BRPI0707059 A BR PI0707059A BR PI0707059 A2 BRPI0707059 A2 BR PI0707059A2
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- Prior art keywords
- oxaliplatin
- liposome
- cancer
- drug
- cisplatin
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- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
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- A—HUMAN NECESSITIES
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- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
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- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| GR20060100144A GR20060100144A (el) | 2006-03-03 | 2006-03-03 | Θεραπεια του καρκινου με χρηση οξαλιπλατινης εγκλεισμενης μεσα σε λιποσωματα και απο κοινου εγκλεισμος στο λιποσωμιακο μοριο περισσοτερων απο ενος φαρμακευτικου παρασκευασματος h gene |
| GR20060100144 | 2006-03-03 | ||
| PCT/GR2007/000015 WO2007099377A2 (en) | 2006-03-03 | 2007-03-05 | Cancer treatments |
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| US9186322B2 (en) | 2002-08-02 | 2015-11-17 | Insmed Incorporated | Platinum aggregates and process for producing the same |
| US9107824B2 (en) | 2005-11-08 | 2015-08-18 | Insmed Incorporated | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
| KR20080094473A (ko) * | 2007-04-20 | 2008-10-23 | 한국화학연구원 | 음이온성 지질나노입자 및 이의 제조방법 |
| KR101560339B1 (ko) * | 2008-01-28 | 2015-10-14 | 나노캐리어 가부시키가이샤 | 의약 조성물 또는 조합제 |
| TWI468188B (zh) * | 2008-01-30 | 2015-01-11 | Univ Tokushima | Anti-cancer effect enhancers consisting of oxaliplatin liposomal preparations and anticancer agents comprising the formulation |
| WO2009111648A1 (en) * | 2008-03-05 | 2009-09-11 | Vicus Therapeutics, Llc | Compositions and methods for mucositis and oncology therapies |
| EP2123258A1 (en) * | 2008-05-23 | 2009-11-25 | Liplasome Pharma A/S | Liposomes for drug delivery |
| WO2010138550A1 (en) * | 2009-05-27 | 2010-12-02 | Northeastern University | Conjugated nanodelivery vehicles |
| IN2012DN02576A (https=) * | 2009-09-21 | 2015-08-28 | Jw Pharmaceutical Corportion | |
| JP5817053B2 (ja) * | 2010-04-02 | 2015-11-18 | 国立大学法人 千葉大学 | 腫瘍特異性を有するリポソーム |
| CN102133176B (zh) * | 2011-03-22 | 2012-09-05 | 济南宏瑞创博医药科技开发有限公司 | 一种奥沙利铂胶束制剂及其制备方法及应用 |
| JP5378469B2 (ja) | 2011-08-11 | 2013-12-25 | 学校法人 日本歯科大学 | 医療用薬剤 |
| EP2883542B1 (en) | 2012-08-10 | 2019-05-01 | Taiho Pharmaceutical Co., Ltd. | Stable oxaliplatin-encapsulating liposome aqueous dispersion and method for stabilizing same |
| US20150258139A1 (en) * | 2012-08-13 | 2015-09-17 | Regulon, Inc. | Methods for treatment of cancer using lipoplatin |
| MA37931A1 (fr) * | 2012-08-13 | 2016-07-29 | Teni Boulikas | Procédés améliorés permettant de traiter un cancer avec une toxicité rénale réduite |
| DK2892524T3 (da) | 2012-09-04 | 2021-01-25 | Eleison Pharmaceuticals LLC | Forebyggelse af pulmonalt kræfttilbagefald med lipid-komplekseret cisplatin |
| EA023757B1 (ru) * | 2012-12-24 | 2016-07-29 | Общество С Ограниченной Ответственностью "Технология Лекарств" | Способ получения липосомальной формы оксалиплатина |
| CA2903234C (en) * | 2013-03-13 | 2018-08-28 | Mallinckrodt Llc | Liposome oxaliplatin compositions for cancer therapy |
| JP6002835B2 (ja) * | 2013-03-27 | 2016-10-05 | 大鵬薬品工業株式会社 | 低用量イリノテカン塩酸塩水和物を含有する抗腫瘍剤 |
| CN103622912B (zh) * | 2013-12-05 | 2016-02-24 | 常州金远药业制造有限公司 | 盐酸多柔比星-多西他赛或紫杉醇脂质体制剂及其制备方法 |
| AU2016219004A1 (en) * | 2015-02-13 | 2017-09-07 | Op Nano Co., Ltd. | Compositions and methods of tumor treatment utilizing nanoparticles |
| US9895313B2 (en) | 2015-03-03 | 2018-02-20 | Cureport, Inc. | Combination liposomal pharmaceutical formulations |
| EP3265063A4 (en) | 2015-03-03 | 2018-11-07 | Cureport, Inc. | Dual loaded liposomal pharmaceutical formulations |
| KR101687735B1 (ko) * | 2015-09-18 | 2016-12-19 | 서울대학교 산학협력단 | 신규의 동결건조보조제 및 새로운 인지질 용해용 혼합용매를 이용한 리포좀 동결분체의 제조방법 |
| WO2017192502A1 (en) * | 2016-05-03 | 2017-11-09 | The American University In Cairo | Liposomal delivery systems for oxaliplatin and in dual drug delivery in combination with chemo-sensitizing and chemo-therapeutic agents |
| WO2017192863A1 (en) * | 2016-05-04 | 2017-11-09 | L.E.A.F. Holdings Group Llc | Targeted liposomal gemcitabine compositions and methods thereof |
| CN106074379B (zh) * | 2016-07-11 | 2019-01-25 | 中国科学院上海药物研究所 | 聚乙二醇化奥沙利铂前药及其制备方法和用途 |
| CN112656764B (zh) * | 2020-12-28 | 2022-09-02 | 吉林大学 | 一种紫杉醇铂类共载靶向长循环脂质体及应用 |
| CN114814023B (zh) * | 2022-04-24 | 2024-07-30 | 江苏省中医院 | 脂质分子在作为胃癌化疗药耐药的预测性标志物中的应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6060080A (en) * | 1990-07-16 | 2000-05-09 | Daiichi Pharmaceutical Co., Ltd. | Liposomal products |
| CA2046997C (en) * | 1990-07-16 | 2000-12-12 | Hiroshi Kikuchi | Liposomal products |
| US6511676B1 (en) * | 1999-11-05 | 2003-01-28 | Teni Boulikas | Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes |
| AU2001275423B2 (en) * | 2000-06-09 | 2007-01-11 | Regulon, Inc. | Encapsulation of polynucleotides and drugs into targeted liposomes |
| CA2383259A1 (en) * | 2002-04-23 | 2003-10-23 | Celator Technologies Inc. | Synergistic compositions |
| US20040022842A1 (en) * | 2002-06-03 | 2004-02-05 | Mebiopharm Co., Ltd. | Liposome preparations containing oxaliplatin |
| JP3415131B1 (ja) * | 2002-06-03 | 2003-06-09 | メビオファーム株式会社 | リポソーム製剤 |
| EP1545459A4 (en) * | 2002-08-02 | 2007-08-22 | Transave Inc | PLATINUM AGGREGATES, AND METHOD FOR MANUFACTURING THE SAME |
| JP2006525368A (ja) * | 2003-05-02 | 2006-11-09 | アロネックス，ファーマシューティカルズ，インコーポレーテッド | 脂質白金錯体およびその使用方法 |
| EP1643971A2 (en) * | 2003-05-22 | 2006-04-12 | Neopharm, Inc. | Liposomal formulations comprising a combination of two or more active agents |
-
2006
- 2006-03-03 GR GR20060100144A patent/GR20060100144A/el not_active IP Right Cessation
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2007
- 2007-03-05 MX MX2008011263A patent/MX2008011263A/es not_active Application Discontinuation
- 2007-03-05 CA CA002644566A patent/CA2644566A1/en not_active Abandoned
- 2007-03-05 WO PCT/GR2007/000015 patent/WO2007099377A2/en not_active Ceased
- 2007-03-05 US US12/281,541 patent/US20090053302A1/en not_active Abandoned
- 2007-03-05 CN CNA2007800139281A patent/CN101522172A/zh active Pending
- 2007-03-05 RS RSP-2008/0388A patent/RS20080388A/sr unknown
- 2007-03-05 EA EA200801912A patent/EA200801912A1/ru unknown
- 2007-03-05 EP EP07712997A patent/EP2001441A2/en not_active Withdrawn
- 2007-03-05 JP JP2008556861A patent/JP2009528340A/ja active Pending
- 2007-03-05 KR KR1020087024248A patent/KR20090023548A/ko not_active Ceased
- 2007-03-05 AU AU2007220263A patent/AU2007220263A1/en not_active Abandoned
- 2007-03-05 BR BRPI0707059-4A patent/BRPI0707059A2/pt not_active IP Right Cessation
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2008
- 2008-09-02 MA MA31204A patent/MA30314B1/fr unknown
- 2008-09-03 TN TNP2008000345A patent/TNSN08345A1/en unknown
- 2008-09-15 NO NO20083927A patent/NO20083927L/no not_active Application Discontinuation
- 2008-09-16 ZA ZA200807934A patent/ZA200807934B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MA30314B1 (fr) | 2009-04-01 |
| RS20080388A (sr) | 2009-07-15 |
| AU2007220263A1 (en) | 2007-09-07 |
| WO2007099377A3 (en) | 2008-04-17 |
| CA2644566A1 (en) | 2007-09-07 |
| MX2008011263A (es) | 2008-12-12 |
| KR20090023548A (ko) | 2009-03-05 |
| WO2007099377A2 (en) | 2007-09-07 |
| EA200801912A1 (ru) | 2009-02-27 |
| EP2001441A2 (en) | 2008-12-17 |
| NO20083927L (no) | 2008-09-15 |
| TNSN08345A1 (en) | 2009-12-29 |
| JP2009528340A (ja) | 2009-08-06 |
| US20090053302A1 (en) | 2009-02-26 |
| GR20060100144A (el) | 2007-10-17 |
| ZA200807934B (en) | 2009-11-25 |
| CN101522172A (zh) | 2009-09-02 |
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