JP2009527484A - （＋）−ｒ−ジロートンの新規結晶形態および医薬組成物 - Google Patents
（＋）−ｒ−ジロートンの新規結晶形態および医薬組成物 Download PDFInfo
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- 229940075582 sorbic acid Drugs 0.000 description 1
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- 238000002560 therapeutic procedure Methods 0.000 description 1
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- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Chemical class OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- JEJAMASKDTUEBZ-UHFFFAOYSA-N tris(1,1,3-tribromo-2,2-dimethylpropyl) phosphate Chemical compound BrCC(C)(C)C(Br)(Br)OP(=O)(OC(Br)(Br)C(C)(C)CBr)OC(Br)(Br)C(C)(C)CBr JEJAMASKDTUEBZ-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
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- A—HUMAN NECESSITIES
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Otolaryngology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77557906P | 2006-02-21 | 2006-02-21 | |
| PCT/US2007/004488 WO2007098189A2 (en) | 2006-02-21 | 2007-02-21 | New crystal forms and pharmaceutical compositions of (+) -r-zileuton |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009527484A true JP2009527484A (ja) | 2009-07-30 |
| JP2009527484A5 JP2009527484A5 (enExample) | 2010-04-08 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008555417A Pending JP2009527484A (ja) | 2006-02-21 | 2007-02-21 | （＋）−ｒ−ジロートンの新規結晶形態および医薬組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8003684B2 (enExample) |
| EP (2) | EP2001861A2 (enExample) |
| JP (1) | JP2009527484A (enExample) |
| AU (1) | AU2007217770B2 (enExample) |
| CA (1) | CA2642216A1 (enExample) |
| WO (1) | WO2007098189A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016534079A (ja) * | 2013-10-30 | 2016-11-04 | クリエント カンパニー， リミテッドＱｕｒｉｅｎｔ Ｃｏ．， Ｌｔｄ． | ジロートンクリーム剤形の局所用抗炎症薬学的組成物 |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8445437B2 (en) * | 2006-07-27 | 2013-05-21 | The Brigham And Women's Hospital, Inc. | Treatment and prevention of cardiovascular disease using mast cell stabilizers |
| JP2010515682A (ja) * | 2007-01-05 | 2010-05-13 | コーナーストーン セラピューティックス インコーポレイテッド | 喘息などの５−リポキシゲナーゼ活性上昇および／またはロイコトリエン活性上昇に関連する状態における使用のためのｒ−ジロートン |
| JP5460600B2 (ja) * | 2007-09-28 | 2014-04-02 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド | 肥満症治療における肥満細胞安定化薬 |
| NZ720946A (en) | 2009-04-29 | 2017-09-29 | Amarin Pharmaceuticals Ie Ltd | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
| PT2959899T (pt) * | 2011-08-23 | 2017-05-18 | Cornerstone Therapeutics Inc | Utilização de zileuton para o tratamento de pólipos nasais em pacientes com fibrose quística |
| US9855243B2 (en) | 2013-10-30 | 2018-01-02 | Qurient Co., Ltd. | Topical anti-inflammatory pharmaceutical composition with zileuton cream formulation |
| US9802926B2 (en) * | 2014-06-20 | 2017-10-31 | Aviragen Therapeutics, Inc. | Anhydrous crystalline free base form of 6-{2-[1 -(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy}-3-ethoxy-1,2-benzisoxazole |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08510252A (ja) * | 1993-05-10 | 1996-10-29 | セプラコール・インコーポレーテッド | 光学的に純粋な（＋）‐ジロイトンを用いた方法および組成 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US279263A (en) * | 1883-06-12 | Eobeet t | ||
| EP0279263B1 (en) * | 1987-02-10 | 1993-08-04 | Abbott Laboratories | Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds |
| US5663368A (en) * | 1993-07-14 | 1997-09-02 | Smithkline Beecham Corporation | Synthesis of acid addition salts of hydroxylamines |
-
2007
- 2007-02-21 JP JP2008555417A patent/JP2009527484A/ja active Pending
- 2007-02-21 EP EP07751259A patent/EP2001861A2/en not_active Ceased
- 2007-02-21 AU AU2007217770A patent/AU2007217770B2/en not_active Ceased
- 2007-02-21 WO PCT/US2007/004488 patent/WO2007098189A2/en not_active Ceased
- 2007-02-21 CA CA002642216A patent/CA2642216A1/en not_active Abandoned
- 2007-02-21 EP EP11176982A patent/EP2409973A1/en not_active Withdrawn
- 2007-02-21 US US11/709,299 patent/US8003684B2/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08510252A (ja) * | 1993-05-10 | 1996-10-29 | セプラコール・インコーポレーテッド | 光学的に純粋な（＋）‐ジロイトンを用いた方法および組成 |
Non-Patent Citations (1)
| Title |
|---|
| JPN6012043935; Ｔｅｔｒａｈｅｄｒｏｎ Ｌｅｔｔｅｒｓ Ｖｏｌ．３５， Ｎｏ．７, 1994, ｐ．１０１１-１０１４ * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016534079A (ja) * | 2013-10-30 | 2016-11-04 | クリエント カンパニー， リミテッドＱｕｒｉｅｎｔ Ｃｏ．， Ｌｔｄ． | ジロートンクリーム剤形の局所用抗炎症薬学的組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| US8003684B2 (en) | 2011-08-23 |
| US20070244185A1 (en) | 2007-10-18 |
| EP2001861A2 (en) | 2008-12-17 |
| AU2007217770A1 (en) | 2007-08-30 |
| CA2642216A1 (en) | 2007-08-30 |
| WO2007098189A3 (en) | 2008-04-03 |
| EP2409973A1 (en) | 2012-01-25 |
| WO2007098189A2 (en) | 2007-08-30 |
| AU2007217770B2 (en) | 2011-09-08 |
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